Clinical trials: Movement Disorders, Functional
Uterine Prolapse
Combined Effects of Pelvic Floor Retraining and Hypopressive Exercises in Uterine Prolapse Outcomes
One common pelvic floor condition, particularly in postpartum or later life, is uterine prolapse. It is caused by weak pelvic floor muscles and connective tissues and often presents with pain, urinary incontinence, and reduced…
- Trial name
- NCT07642180
- Testing
- Functional Movement Retraining + Hypopressive Exercises, Pelvic Floor Functional Movement Retraining
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Parkinson Disease, Orthostatic Hypotension
Cardiovascular Effects of Exercise in Patients With Parkinson's Disease
Abnormalities in the regulation of cardiovascular system due to autonomic nervous system (ANS) dysfunction may lead to a sudden decline in blood pressure (BP) upon standing, sitting or performing activities/exercises in patients…
- Trial name
- NCT03343574
- Testing
- Abdominal Strengthening Exercise
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- Faizan Ahmed
Parkinson's Disease
Study to Assess Real Life Effectiveness of Foslevodopa/Foscarbidopa in Adult German Participants at Initial Stages of Advanced Parkinson's Disease (EARLY-FOS)
Parkinson's disease (PD) is a neurological condition, which affects the brain. PD gets worse over time, but how quickly it progresses varies a lot from person to person.
- Trial name
- NCT06916507
- Where
- 19 sites in Germany
- Volunteers
- 125 people
- Sponsor
- AbbVie
Parkinson Disease, Parkinson Disease, Secondary
Accelerated Temporal Interference Stimulation on Bilateral Subthalamic Nucleus for Parkinson's Disease and Secondary Parkinson's Syndrome
This clinical trial will evaluate the efficacy of accelerated Temporal Interference Stimulation (TIS) as a therapeutic intervention for individuals diagnosed with Parkinson's disease or secondary Parkinson's syndrome.
- Trial name
- NCT07568067
- Testing
- Temporal Interference Stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Ke Dong, MD
Parkinson Disease, Essential Tremor
Brain Network Activation in Patients With Movement Disorders
The diagnosis and management of movement disorders, such as Parkinson's disease (PD), parkinson-plus syndromes (PPS), dystonia, essential tremor (ET), normal pressure hydrocephalus (NPH) and others is challenging given the lack…
- Conditions
- Parkinson Disease, Essential Tremor, Dystonia, Normal Pressure Hydrocephalus
- Trial name
- BNA-MDi (NCT03269201)
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Sheba Medical Center
Hip Dysplasia, Congenital
Developmental Hip Dysplasia and Physical Therapy
Developmental Hip Displasia (DDH) can cause various degenerations or compensatory adaptations in the spine and knee joint, especially in the hip joint.
- Trial name
- NCT04006574
- Testing
- Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people
- Sponsor
- Hacettepe University
Acupuncture, Parkinson's Disease
The Study of Acupuncture on Vascular and Functional Neuroimaging in Parkinson's Disease Patients With Sleep Disorders
The purpose of the study is to compare vascular and functional neurological changes of acupuncture in patients with Parkinson's Disease and Sleep Disorders.
- Conditions
- Acupuncture, Parkinson's Disease, Sleep Disorders, Neuroimaging
- Trial name
- NCT03501004
- Testing
- Sterile acupuncture needles for single use
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Tsinghua University
Stroke
Comparing Mirror Therapy and CIMT for Hand and Arm Function in Post-Stroke Patients
The goal of this clinical trial is to find out whether Mirror Therapy (MT) combined with Constraint-Induced Movement Therapy (CIMT) improves hand and arm function after a stroke.
- Trial name
- NCT07139015
- Testing
- CONSTRAINT-INDUCED MOVEMENT THERAPY, MIRROR THERAPY
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Scapular Dyskinesis
Effects of Motor Control Retraining and Scapular Stabilization Exercises in Females With Scapular Dyskinesia.
To evaluate the combined effects of motor control retraining and scapular stabilization exercises on pain reduction, muscle strength improvement, and functional enhancement in breastfeeding females diagnosed with scapular…
- Trial name
- NCT07576426
- Testing
- motor control retraining, scapular stabilization exercises
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Parkinson's Disease (PD)
A Phase 2 Study to Assess the Effects of SUL-238 on High Energy Phosphates With ³¹P-MRS in Patients With Early, Untreated Parkinson's Disease
The main goal of the study is to investigate how well the new drug SUL-238 works in Parkinson's Disease (PD). This is done by means of an MRS scan. An MRS scan is similar to a regular MRI scan.
- Trial name
- SHEPHERD (NCT07322887)
- Testing
- SUL-238 (1500 mg t.i.d.) film-coated tablets, SUL-238 (500 mg t.i.d.) film-coated tablets
- Where
- Netherlands
- Volunteers
- 45 people
- Sponsor
- GEN İlaç ve Sağlık Ürünleri A.Ş.
Accidental Fall, Postural Balance
The Relation Between Movement Patterns, Balance Performance, Function of the Inner Ear and Falls
Falls are one of the most common reasons for immobilisation and death in elderly population. This study aims at studying falls among a group of older people.
- Conditions
- Accidental Fall, Postural Balance, Movement Disorders in Old Age
- Trial name
- NCT03503916
- Where
- Sweden
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Lund University
Parkinson Disease
Neural Correlates of Impulsivity in Idiopathic REM Sleep Behavior Disorder
This study aims to investigate the neural correlates (structural changes, functional connectivity, and structural connectivity of brain structures in prefrontal cortex and basal ganglia) of impulsivity by measuring structures and…
- Trial name
- NCT05353855
- Testing
- No intervention
- Where
- Hong Kong
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
PARKINSON DISEASE (Disorder)
taVNS on Functional Mobility in People With DP
Parkinson's disease (PD) is characterized by motor impairments such as bradykinesia accompanied by resting tremor and/or rigidity.
- Trial name
- NCT07366411
- Testing
- Active taVNS
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Universidade Federal de Pernambuco
Functional Movement Disorders
Chinese FMDs Registry
The purpose of the Chinese Functional Movement Disorders Registry (FMDs-China) is to develop a database of patients with Functional Movement Disorders (FMDs) in China.
- Trial name
- NCT05201521
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Ruijin Hospital
Conversion Disorder
Contribution of Inflammation and Neuronal Integrity Markers in Patients With First-episode Conversive Motor Disorder
Conversion disorders, also called "dissociative disorders" (ICD-10), or "functional neurological disorders" (DSM-5), are a common condition, with a prevalence of 1-10% in medical and surgical inpatients (Toone 1990), and 10-30%…
- Trial name
- HYCOIN (NCT05305014)
- Testing
- blood inflammatory markers (TNF-α, IL1ra, RsIL-2, IL-6, IL-10, IL-18, IFNγ, MCP-1/CCL2 GFAP)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Parkinson Disease
Application of Transcranial Direct Current Stimulation (tDCS) for Gait Function Improvement of Parkinson's Disease Patient
The purpose of this study was to investigate the effect of simultaneous application of transcranial direct current stimulation (tDCS) and treadmill gait training for gait function recovery in Parkinson's disease patients with…
- Trial name
- NCT04591236
- Testing
- Brain stimulation, Treadmill gait training
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Samsung Medical Center
Dementia, Lewy Body
ANeED Joint Effort 21: eHealth and a PPI Program in Dementia With Lewybodies (DLB)
The goal of the study is to develop predictive algorithms and digital biomarkers to capture disease fluctuations in (prodromal) dementia with lewybodies (DLB) patients and to improve treatment, diagnosis and prognosis of the…
- Trial name
- JointEffort21 (NCT05773443)
- Testing
- Digital biomarkers
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- University of Bergen
Stroke, Parkinson Disease
Feasibility of Two New Software Modules for the Rehabilitation of Patients With Neuromuscular Upper Limb Impairments
Introduction: In the recent past, medical training systems using virtual reality (VR) have been introduced to neurorehabilitation to train motor function deficits in patients.
- Conditions
- Stroke, Parkinson Disease, Traumatic Brain Injury, Guillain-Barre Syndrome
- Trial name
- NCT03268304
- Testing
- VR-based training including AO and MI
- Sponsor
- Reha Rheinfelden
Hemiplegia, Cerebral Palsy
Bimanual Training in Children With Hemiplegia
A randomized control trial of bimanual training in children with hemiplegia. The protocols have been developed at Columbia University to be child friendly and draws upon our experience since 1997 with constraint-induced movement…
- Conditions
- Hemiplegia, Cerebral Palsy, Children
- Trial name
- HABIT (NCT01413594)
- Testing
- HABIT
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Teachers College, Columbia University
Hospital Mobility, Mobility Limitation
An INtervention TO Improve MOBility of Older Hospitalized Patients
Low mobility during an acute care hospitalization is very frequent, particularly among older patients, and associated with adverse outcomes, such as persistent functional decline, institutionalization and death.
- Conditions
- Hospital Mobility, Mobility Limitation, Life-Space, Functional Status
- Trial name
- INTOMOB (NCT05639231)
- Testing
- INTOMOB intervention
- Where
- 4 sites in Switzerland
- Volunteers
- 383 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern