Clinical trials: Movement Disorders, Functional
Essential Tremor
Functional Outcomes of Awake vs. Asleep Deep Brain Stimulation (DBS) for Essential Tremor
Recently, there has been increasing interest in performing DBS under general anesthesia, where the stimulated targets are located anatomically (i.e.
- Trial name
- NCT02418858
- Testing
- Deep Brain Stimulation surgery
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
Parkinson Disease
BIG for Life: a Pilot Study
This research study will aim to evaluate BIG for LIFE as a group exercise program, and determine whether three time a week exercise sessions with heart rate monitoring is beneficial to maintain or improve physical function…
- Trial name
- NCT04090476
- Testing
- Exercise
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Brain Injury, Vascular, Sequelae
The Effectiveness of Core Stability Exercises
This study assess the effectiveness of core stability exercises performed in subacute phase of stroke. Half of participants will receive conventional physiotherapy, while the other half will receive core stability exercises and…
- Conditions
- Brain Injury, Vascular, Sequelae, Stroke Syndrome, Movement; Disorder, Treatment-Induced
- Trial name
- CORE (NCT03975985)
- Testing
- Core stability exercises (CSE), Conventional Physiotherapy
- Where
- Spain
- Volunteers
- 87 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Healthy Older Adults, Parkinson Disease
Brain Activity, Cognitive Function, and Walking Ability in Parkinson's Disease
The dual-task automated walking performance in people with Parkinson\'s disease (PD) is affected by their gait disturbances and impaired executive functions.
- Trial name
- NCT06588920
- Testing
- Cognitive function, gait, and electroencephalogram
- Where
- 2 sites in Taiwan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Parkinson Disease
Sleep Quality, Cognition, and Disease Severity in Parkinson's Disease
The goal of this observational study is to investigate the relationship between sleep quality, cognitive functions, and disease severity in individuals with Parkinson's disease.
- Trial name
- NCT07536490
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Ankara University
Parkinson's Disease
The Effect of Rasagiline on Cognition in Parkinson's Disease
While Parkinson's disease has historically been defined in terms of its motor symptomatology, studies have shown that non-motor deficits form an important part of the syndrome.
- Trial name
- NCT01382342
- Testing
- Rasagiline
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Brown University
Functional Neurological Symptom Disorder
Eye MOvement DesensItisation and Reprocessing Therapy (EMDR) for FunctIonal Neurological Disorder (FND)
Functional Neurological Disorder (FND) is a problem with the functioning of the nervous system and how the brain and body send and receive signals, rather than due to neurological disease or injury.
- Trial name
- MODIFI (NCT05455450)
- Testing
- Eye movement desensitisation and reprocessing therapy, Neuropsychiatric care
- Where
- 2 sites in United Kingdom
- Volunteers
- 50 people
- Sponsor
- South West London and St George's Mental Health NHS Trust
Parkinson's Disease, Exercise Therapy
Partnered Dance Aerobic Exercise as a Neuroprotective, Motor and Cognitive Intervention in Parkinson's Disease
Parkinson's disease (PD) is a difficult to treat condition that impairs mobility and thinking. It is not fully treated by drugs and surgery. Two priority issues for most people with PD are "OFF-time" and Cognitive impairment.
- Conditions
- Parkinson's Disease, Exercise Therapy, Cognition
- Trial name
- PDAE in PD (NCT04122690)
- Testing
- PDAE, WAE
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- VA Office of Research and Development
Executive Dysfunction, Parkinson Disease
High-Speed Yoga and Executive Function
The purpose of this research study is to establish if a novel high-speed yoga program which incorporates visual cues can make a positive change in the participant's ability to make decisions and move as measured by several…
- Conditions
- Executive Dysfunction, Parkinson Disease, Quality of Life
- Trial name
- NCT04215900
- Testing
- High-speed yoga multi-directional yoga
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Miami
Kinesiophobia (Fear of Movement), Rhematoid Arthritis
Kinesiophobia in Rheumatoid Arthritis: Associations With Functional Disability, Disease Activity, and Related Clinical Factors
Objectives: Impairment of physical function is a core feature of RA, particularly in patients with high disease activity where pain and inflammation directly limit movement.
- Conditions
- Kinesiophobia (Fear of Movement), Rhematoid Arthritis, Rheumatoid Arthritis (RA), Rheumatoid
- Trial name
- NCT07435272
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Minia University
Psychogenic Non-Epileptic Seizure
TMS vs Conventional Therapy for the Treatment of Functional Neurological Non Epileptic Seizure Disorder
The aim of the study is to compare the effect of Transcranial Magnetic Stimulation (TMS) versus treatment with selective serotonin reuptake inhibitors (SSRIs), in patients with diagnosis of Functional Neurological Non Epileptic…
- Trial name
- NCT05241366
- Testing
- Transcranial Magnetic Stimulation
- Where
- Mexico
- Volunteers
- 28 people
- Sponsor
- El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez
Parkinson Disease, Balance
Non-motor Symptoms, Balance, Muscle Strength, and Functional Mobility in Patients With Parkinson's Disease
The purposes of this study is to examine balance, muscle strength, and mobility in relation with non-motor symptoms (NMSs) in patients with Parkinsosn's Disease (PD).
- Conditions
- Parkinson Disease, Balance, Muscle Strength, Mobility
- Trial name
- NCT04420910
- Testing
- Non-Motor Symptoms, Balance, Lower Limb Strength
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Patellofemoral Pain Syndrome
The Movement Control Training Associated With Conventional Physical Therapy is More Effective Than Conventional Physical Therapy Alone in Pain and Functional Performance?
Assess pain, performance function, hip and knee strength and kinematics of trunk and lower limbs during single leg hop test after movement control training associated to hip and knee muscle strengthening.
- Trial name
- MCTACPTMECPTA (NCT02624245)
- Testing
- Conventional Physical Therapy
- Where
- Brazil
- Volunteers
- 34 people
- Sponsor
- University of Nove de Julho
Parkinson's Disease
Galantamine Executive Function in Parkinson's Disease
The aim of the study is to determine whether galantamine stabilizes or improves thinking abilities in individuals with Parkinson's disease.
- Trial name
- NCT00211588
- Testing
- galantamine
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Memorial Hospital of Rhode Island
Stroke, Hemiparesis
Constraint-Induced Movement Therapy (CIMT) with Motor Relearning Program (MRP) and Bobath Approach to Augment Functional Motor Recovery of Chronic Hemiparetic Arm
Hemiparesis is a condition characterized by weakness or the inability to move on one side of the body, making it difficult to perform everyday activities like eating or dressing (Iswatun et al., 2022).
- Conditions
- Stroke, Hemiparesis, Hemiparesis After Stroke, Motor Function
- Trial name
- CIMT-MRP (NCT06806553)
- Testing
- Constraint-Induced Movement Therapy (CIMT) With Motor Relearning Program (MRP), Bobath Therapy
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- University of Lahore
Dysphagia, Gastroesophageal Reflux
Stimulation of Sensation and Improvement in Swallowing Using Oral Capsaicin
This is a research study to learn more about whether capsaicin, a natural ingredient of chili peppers that makes them taste "hot", can improve swallowing function.
- Trial name
- NCT01053286
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Parkinson Disease, Huntington Disease
Group Drum-Based Music Therapy Intervention for Parkinson's Disease/Huntington's Disease
Participants in this study (18-89 years) with Parkinson's disease or Huntington's disease receive drum classes twice a week for 12 weeks (24 lessons).
- Trial name
- NCT05157074
- Testing
- Group Drumming Music Therapy
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Globus
The Effect of Laryngeal Manual Therapy as a Management of Globus
The purpose of this study is to assess the effect of laryngeal manual therapies in the treatment of globus (sensation of a lump in the throat).
- Trial name
- NCT04436146
- Testing
- laryngeal manual therapies
- Where
- Israel
- Volunteers
- 70 people
- Sponsor
- HaEmek Medical Center, Israel
Parkinson Disease
Multiple Practice Contexts to Reduce Context-dependent Learning in PD
Context-dependent learning (CDL) is a phenomenon that an individual demonstrates superior motor performance in the environmental context in which a task was originally learned and practiced, while the performance may decrease if…
- Trial name
- NCT03368443
- Testing
- treadmill training and overground gait training
- Where
- Taiwan
- Volunteers
- 58 people
- Sponsor
- National Taiwan University Hospital
Huntington Disease
Impact of Deutetrabenazine on Functional Speech and Gait Dynamics in Huntington Disease
Examine the effects of deutetrabenazine on functional speech and gait impairment
- Trial name
- NCT04713982
- Testing
- Deutetrabenazine
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Vanderbilt University Medical Center