Clinical trials: Mucosal Erosion
Mucosal Wound, Mucosal Erosion
The Effect of Changes in the Frequency of Endotracheal Tube Repositioning in Intensive Care Units on the Prevention of Oral Mucosal Pressure Injuries
Intensive care units (ICUs) are care centers equipped with a wide range of technological tools and devices used to provide the highest level of care to individuals whose lives are at risk, requiring a multidisciplinary team…
- Conditions
- Mucosal Wound, Mucosal Erosion, Mucosal Irritation, Endotracheal Intubation Fixation
- Trial name
- PreventionMMPI (NCT07390162)
- Testing
- Changes in the frequency of endotracheal tube repositioning
- Volunteers
- 230 people
- Sponsor
- Hacettepe University
Gastrointestinal Ulcer (Peptic) or Erosion, Anti-Platelet Therapy
Proton Pump Inhibitor Preventing Upper Gastrointestinal Injury In Patients On Dual Antiplatelet Therapy After CABG
The purpose of this study is to compare the efficacy and safety for 12- vs. 1-month of pantoprazole treatment in preventing dual antiplatelet therapy (DAPT)-related upper gastrointestinal mucosal injury after coronary artery…
- Conditions
- Gastrointestinal Ulcer (Peptic) or Erosion, Anti-Platelet Therapy, Coronary Artery Bypass
- Trial name
- DACAB-GI-2 (NCT03908593)
- Testing
- Pantoprazole
- Where
- China
- Volunteers
- 232 people
- Sponsor
- Ruijin Hospital
Mucosal Erosion
Pre-medication With N-acetylcysteine and Simethicone to Improve Mucosal Visibility During Gastroduodenoscopy
In this study, we aimed to compare combined premedication with simethicone or N-acetylcysteine (NAC) for mucosal visualisation during esophagogastroduodenoscopy (EGD).
- Trial name
- SIMETHICONE (NCT05951712)
- Testing
- Simethicone 150mg, N Acetyl cysteine 600mg, Simethicone 150mg plus N Acetyl cysteine 600 mg
- Where
- India
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Mucosal Erosion
Risk Factors of Cat Scratch Colon Developing.
This study was designed to: estimate the incidence of cat scratch colon in the investigators environment; explore the diseases associated to its development; identify the factors related to its development; and assess its…
- Trial name
- CSC (NCT01574547)
- Volunteers
- 10,715 people
- Sponsor
- University Hospital of the Nuestra Señora de Candelaria
Gastroduodenal Ulcerations, Erosion
Clinical Trial Evaluating Gastrointestinal Damage Following Administration PL3100 or Naproxen in At-Risk Adults
The purpose of this study is to determine the subchronic gastrointestinal (GI) safety of PL3100 versus Naproxen in normal healthy volunteers.
- Trial name
- NCT01139190
- Testing
- PL3100, Naproxen
- Where
- 2 sites in United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- PLx Pharma
Oral Mucositis, Nausea
ZeroTolerance Mucositis: Managing Oral and Alimentary Mucositis With High Potency Sucralfate - ProThelial
RATIONALE: Polymerized (cross-linked) sucralfate malate paste (ProThelial) may be an effective single therapy approach for the management of chemoradiation mucositis, treating and preventing its occurrence in the oral cavity…
- Conditions
- Oral Mucositis, Nausea, Vomiting, Diarrhea
- Trial name
- NCT02016807
- Testing
- ProThelial
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Ashley Downs Bioscience
Mucosal Erosion, Gingival Recession
Patient-reported Outcomes of Donor Site Healing Using Different Palatal Protection Techniques
This study has been initiated to evaluate the question, "What is the best way to protect the palate after a gum graft is removed?" The overall objective is to determine if there is a difference in PROMs of donor site healing…
- Trial name
- NCT06892496
- Testing
- Visual Analog scale (VAS) questionnaire, Vacuum-formed retainer (VFR) technique, 3-D printed acrylic resin stent (3DS) technique
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Virginia Commonwealth University
Normal Subjects
Rabeprazole Protection of Aspirin Induced Gastric Damage.
To determine the effectiveness of rabeprazole in preventing or decreasing acute gastroduodenal injury caused by therapeutic doses of aspirin in a placebo-controlled, randomized, double-blind parallel group study.
- Trial name
- NCT00220857
- Testing
- Rabeprazole
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Temple University
GERD
Biology in Patients With Reflux Esophagitis
GERD is a common condition in the western world. In most cases, the diagnostic is established by good response to empiric proton pump inhibitor (PPI) therapy.
- Trial name
- BENCH (NCT01194323)
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Vanderbilt University Medical Center