Clinical trials: Mucosal Inflammation
Peri-implant Mucositis
Efficacy of an Oral Hygiene Implant Protocol
This study is designed to evaluate the effectiveness of cleaning around implants that hold a full denture in the mouth. Different oral hygiene protocols will be compared.
- Trial name
- NCT04462341
- Testing
- Water Flosser, Manual Toothbrush
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Water Pik, Inc.
Peri-Implantitis, Peri-implant Mucositis
Peri-implantitis Implantoplasty Treatment
This double arm, split-mouth, single centre, controlled, randomised clinical study is designed to examine the effect of implantoplasty in treatment of peri-implantitis.
- Trial name
- NCT04052373
- Testing
- Implantoplasty, Open flap debridement alone
- Where
- 2 sites in Norway
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Edentulous Alveolar Ridge, Peri-Implantitis
Soft Tissue Response to Different Restorative Materials Used in Implant Dentistry
The goal of this clinical trial is to learn how different materials used in dental implants affect the surrounding gum tissue in adults who need dental implants.
- Conditions
- Edentulous Alveolar Ridge, Peri-Implantitis, Peri-implant Mucositis, Prosthetic Infection
- Trial name
- NCT06554041
- Testing
- Dental Crown with Titanium-Abutment, Dental Crown with PEEK (Polyetheretherketone)-Abutment, Dental Crown with Zirconia-Abutment
- Where
- Lithuania
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Harvard Medical School (HMS and HSDM)
Colonoscopy
Tolerability, Efficacy and Mucosal Inflammation Associated With Orally Administered Colon Cleansing for Colonoscopy
Colonoscopy is the gold standard investigation for assessing the lining of the colon. Colon cleansing preparations are required to be taken prior to colonoscopy to provide effective visualisation and identification of any…
- Trial name
- NCT00750763
- Testing
- Colonlytely, Picolax/Picoprep, Fleet
- Where
- Australia
- Volunteers
- 676 people, healthy volunteers welcome
- Sponsor
- Fremantle Hospital and Health Service
Oral Mucositis
Hexetidine and Chlorobutanol for Lesions Due to Prostheses
Objectives: The study aimed at assessing the efficacy of a new mouthwash in treating oral lesions due to removable prostheses. Methods: The present prospective randomized clinical trial was performed on 44 patients.
- Trial name
- NCT01115049
- Testing
- chlorobutanol, hexetidine, Chlorhexidine
- Where
- Italy
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Federico II University
Mouth Diseases
Optical Sensor for Photodynamic Detection of Oral Pathology
Overall objective of this work is to develop better ways of detecting, diagnosing and measuring oral diseases and structures using light and optical approaches.
- Trial name
- NCT00540774
- Testing
- detection of oral pathology
- Where
- United States
- Volunteers
- 1,004 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Peri-Implantitis, Peri-implant Mucositis
Evaluation of the Patient's Risk Profile Using the Peri-implantitis Risk Diagram
Various risk factors defined in the literature should be eliminated in order for the patient to be able to use implant-supported prostheses for a longer period of time.
- Conditions
- Peri-Implantitis, Peri-implant Mucositis, Dental Implant Failed
- Trial name
- NCT05618171
- Testing
- Evaluation of the patient's pre- and post-treatment risk profile using the peri-implantitis risk diagram
- Where
- Turkey (Türkiye)
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Berceste Guler
Peri-implant Mucositis, Peri-Implantitis
Monitoring of Non-Surgical Treatment of Peri-implantitis
This study aimed to investigate the response to non-surgical treatment of peri-implantitis diseases during the maintenance phase.
- Trial name
- NCT06408467
- Testing
- aMMP-8 diagnostic test
- Where
- Finland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lahanna oy
Dental Implant Failed, Peri-implant Mucositis
Erythritol vs Ultrasonic Scaler Prophylaxis Systems on Dental Implants With Crowns Made by Different Materials
The aim of the study is to assess which prophylaxis methods is the most suitable for peri-implant hygiene between erythritol and ultrasonic scaler with peek inserts. A randomized clinical trial will be conducted on the patient.
- Conditions
- Dental Implant Failed, Peri-implant Mucositis, Peri-Implantitis
- Trial name
- NCT06288919
- Testing
- Erythritol prophylactic powders, Ultrasonic scaler with peek inserts
- Where
- Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Peri-Implant Health, Peri-Implantitis and Peri-implant Mucositis
Monitoring of Implant Diseases: Diagnosis and Monitoring With aMMP-8 Test Technology
68 patients underwent the aMMP-8 chair-side test as well as clinical traditional measurement methods. Those who had one or more implants in their mouth were selected as patients.
- Trial name
- IMP_TRE (NCT06761521)
- Testing
- Peri-Implantitis and Peri-implant mucositis
- Where
- Finland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hanna Lahteenmaki
Peri-Implant Mucositis
Short Versus Standard Dental Implants: Clinical and Biomarker Outcomes
This study compares two types of dental implants, short implants (6 millimeters or less in length) and standard implants (longer than 8 millimeters), to evaluate their effect on the health of the gum and bone tissue surrounding…
- Trial name
- NCT07828067
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Inonu University
Dental Implants, Cigarette Smoking
Triclosan Toothpaste as a Preventive Strategy of Mucositis in Smokers
The purpose of this trial was to determine the effect of a triclosan-containing toothpaste in the clinical parameters and in the profile of osteo-immunoinflammatory mediators in the peri-implant crevicular fluid (PICF) as a…
- Trial name
- NCT03241407
- Testing
- triclosan/copolymer/fluoride toothpaste
- Where
- Brazil
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Paulista University
Peri-Implantitis, Mucositis
Exploring the Relationship Among Dental Caries, Nutritional Habits and Peri-implantitis
Aim: A study was made of the prevalence, co-occurrence and association among caries, nutritional habits and peri-implant disease, with an analysis of the influence of other patient and implant factors upon peri-implant disease.
- Conditions
- Peri-Implantitis, Mucositis, Caries,Dental, Nutrition
- Trial name
- NCT04439877
- Testing
- Peri-implant disease diagnosis
- Where
- Spain
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Peri-Implantitis and Peri-implant Mucositis
Risk Assessment of Proximal Contact Loss Between Implant-supported Prostheses and Adjacent Teeth.
In this study, we collected and analysed the review results of 100 patients over 18 years of age who received implant fixed restorations in the Department of Stomatology of the First Hospital of Nanjing, China.
- Trial name
- NCT06475313
- Testing
- plaque index assessment, periodontal probing, Bleeding on probing (BOP), Prosthetic adjacency check, initial occlusal contact, maximum occlusal contact, and filling of the cusps.
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Mucositis
Use of Probiotics in Oral Health of Patients With Dental Implants
The aim of this study was evaluate the effects of the oral probiotic Lactobacillus reuteri Prodentis upon the peri-implant health of edentulous patients with dental implants and peri-implant mucositis, establishing comparisons…
- Trial name
- NCT01974596
- Testing
- Probiotic tablets of Lactobacillus reuteri
- Where
- Spain
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Vaginal Inflammation, Vaginal Infections
Identification of Novel Biomarkers of Cervicovaginal Mucosal Inflammation
This study investigates the response of vaginal and cervical tissue after exposure to three vaginal products: hydroxyethyl cellulose (HEC) placebo, nonoxynol-9 (N9) and imiquimod (IMQ) cream.
- Trial name
- Biomarkers (NCT01593124)
- Testing
- Imiquimod, Nonoxynol-9
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- CONRAD
Septic Shock
Barrier Function and Production of Inflammatory Cytokines in the Rectal Mucosa in Patients With Septic Shock
Life-threatening infection impairs bloodflow to the gut, thereby causing less delivery of oxygen. This leads to increased formation of different inflammatory and infectious markers.
- Trial name
- NCT00378586
- Testing
- Rectal biopsy, Measurement of inflammatory markers in the rectal mucosa, Measurement of rectal lactic acid
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Vaginitis, Radiotherapy Induced Mucositis
Clinical Study on the Prevention and Treatment of Radiation Vaginitis With Triethanolamine Cream
The objective of this clinical trial is to understand whether triethanolamine cream can prevent and treat acute radiation vaginitis. It will also learn about the safety of triethanolamine cream.
- Trial name
- NCT07492654
- Testing
- Trolamine (Biafine)
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Fujian Cancer Hospital
Peri-implant Mucositis, Implant Complication
Influence of Soft Tissue Thickness Upon Dental Implant Esthetics
Since the beginning of the implant dentistry, a large variety of materials have been used for restoring single or multiple implants, such as gold, titanium, alumina (Al2O3), and zirconia (ZrO2).
- Trial name
- NCT04805138
- Testing
- Spectrophotometer
- Where
- Spain
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Asthma; Eosinophilic, Asthma
Nasal Inflammation Following Endotoxin Challenge in Patients With Asthma
A phase I clinical research study aimed at determining mechanisms that regulate airway mucosal inflammation in asthma endotypes using intranasal administration of endotoxin (lipopolysaccharide from E.
- Trial name
- Nasal-LPS (NCT06270576)
- Testing
- Lipopolysaccharides
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Jewish Health