Clinical trials: Multiple Sclerosis Fatigue
Rehabilitation
Changes in Physical Activity in All Day Life in People With MS Before and After Rehabilitation
The primary objective is to observe the impact of in-patient rehabilitation on physical activity in daily life using miniature, wearable sensors, fixed on the shoes. These sensors record data about various aspects of walking.
- Trial name
- NCT03769636
- Testing
- GaitUp Physilog 5
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Klinik Valens
Multiple Sclerosis
Acupressure in MS Patients
This study aims to evaluate the effects of acupressure therapy on patients with Multiple Sclerosis (MS). MS is a chronic autoimmune disease affecting the central nervous system, characterized by inflammation, demyelination, and…
- Trial name
- APEX-MS (NCT06755463)
- Testing
- Self-acupressure education
- Volunteers
- 82 people
- Sponsor
- Abant Izzet Baysal University
Multiple Sclerosis
Endurance and Walking Training by Nordic Walking in Multiple Sclerosis
Walking capacity is one of the most valuable body functions among persons with multiple sclerosis (MS) and it is one of the most frequently affected, even in early stages of the disease.
- Trial name
- NCT03976128
- Testing
- Nordic Walking Training, Conventional endurance training
- Where
- Spain
- Volunteers
- 66 people
- Sponsor
- Multiple Sclerosis Center of Catalonia
Multiple Sclerosis, Fatigue
Ketamine for Treatment of MS Fatigue
Multiple sclerosis (MS) is an inflammatory, demyelinating and degenerative disease of the central nervous system and, after trauma, is the most common cause of disability in young adults, affecting more than 400,000 individuals…
- Trial name
- NCT03500289
- Testing
- Ketamine, Midazolam
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Johns Hopkins University
Multiple Sclerosis, Fatigue
The Effect of the Nurses Support Program on Fatigue in MS Patient
The research will be carried out as a randomized controlled experimental study to examine the effect of a nursing support program supported by a Web-based education program on the management of fatigue symptoms of patients who…
- Conditions
- Multiple Sclerosis, Fatigue, Sleep Hygiene, Quality of Life
- Trial name
- NCT06166043
- Testing
- NURSE FOLLOW-UP PROGRAM SUPPORTED WITH WEB-BASED EDUCATION
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul University - Cerrahpasa
Multiple Sclerosis, Chronic Pain
MS Symptom Management Study
People with Multiple Sclerosis (MS) often have pain and/or fatigue. Unfortunately, available treatments provide inadequate relief for the majority of these individuals.
- Conditions
- Multiple Sclerosis, Chronic Pain, Fatigue
- Trial name
- ENHANCE (NCT02474940)
- Testing
- Intervention #1, Intervention #2, Intervention #3
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- University of Washington
Multiple Sclerosis, MS, Multiple Sclerosis
Transcranial Direct Current Stimulation for Fatigue, Mood, and Cognition in Multiple Sclerosis
Multiple sclerosis (MS) is a chronic, inflammatory and disabling disease of the Cnetral Nervous System characterized by relapsing and / or progressive somatosensory, motor and vestibular clinical manifestations.
- Conditions
- Multiple Sclerosis, MS, Multiple Sclerosis, Multiple Sclerosis (MS) - Relapsing-remitting, Multiple Sclerosis (MS) Primary Progressive
- Trial name
- NCT07680738
- Testing
- Transcranial Direct Current Stimulation
- Where
- Mexico
- Volunteers
- 38 people
- Sponsor
- Universidad de Almeria
All Multiple Sclerosis Patients
Fatigue Treatment Using Provigil
To determine whether therapy with Modafinal(Provigil) is safe and effective in fatigue in MS Patients
- Trial name
- NCT00220506
- Testing
- Provigil
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Sheba Medical Center
Multiple Sclerosis, Balance
Vestibular Rehabilitation for Persons With Multiple Sclerosis: Who Benefits the Most? (MSVR3trial)
Impaired standing balance, fatigue and abnormal eye movements are common problems in persons with MS. These complaints are related to advanced disability and decreased quality of life for persons with MS.
- Conditions
- Multiple Sclerosis, Balance, Fatigue, Eye Movement
- Trial name
- NCT01698086
- Testing
- Vestibular rehabilitation: balance and eye movement exercises
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- University of Colorado, Denver
Multiple Sclerosis, Remitting-Relapsing Multiple Sclerosis
Cognitive Performance, Sleep Disturbances and Fatigue in Multiple Sclerosis
Fatigue is a prevalent symptom in patients with multiple sclerosis (MS) and is associated with considerable impairment in quality of life as well as loss of occupational capacity.
- Conditions
- Multiple Sclerosis, Remitting-Relapsing Multiple Sclerosis, Primary Progressive Multiple Sclerosis, Secondary Progress Multiple Sclerosis
- Trial name
- NCT07426991
- Testing
- No Intervention: Observational Cohort
- Where
- 2 sites in Germany
- Volunteers
- 837 people, healthy volunteers welcome
- Sponsor
- Heinrich-Heine University, Duesseldorf
Multiple Sclerosis, Relapsing-Remitting
Examining Effects of Ocrevus on Cognitive Fatigue Using fMRI
The purpose of this research study is to investigate the effectiveness of MS Disease modifying medications on cognitive fatigue in persons with relapsing remitting multiple sclerosis (RRMS).
- Trial name
- NCT04448977
- Testing
- Ocrevus
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Multiple Sclerosis, Fatigue
Bright Light Therapy as Possible Treatment Option for MS-Fatigue
This study aims to investigate the effect of a 2-week trial of bright light therapy (BLT, 10.000 lx) on fatigue in multiple sclerosis (MS) patients.
- Trial name
- NCT04681586
- Testing
- bright light therapy, dim red light
- Where
- Austria
- Volunteers
- 36 people
- Sponsor
- Medical University of Vienna
Multiple Sclerosis, Heat Tolerance
Cooling During Inpatient Rehabilitation in Persons With MS
The goal of this clinical trial is to shed light on the use of cooling during intensive active training sessions during a three-week multidisciplinary inpatient rehabilitation stay in persons with Multiple Sclerosis.
- Conditions
- Multiple Sclerosis, Heat Tolerance, Fatigue Symptom
- Trial name
- CoolEx (NCT07852156)
- Testing
- Wearing a cooling vest during intensive, active training sessions, Control
- Where
- Switzerland
- Volunteers
- 42 people
- Sponsor
- Klinik Valens
Multiple Sclerosis, Multiple Sclerosis (MS) - Relapsing-remitting
The Effect of Virtual Reality on Fatigue and Functional Capacity in Patients With MS
This clinical trial aims to evaluate the effectiveness of virtual reality (VR) as a complementary intervention to traditional physical therapy for individuals diagnosed with Multiple Sclerosis (MS).
- Conditions
- Multiple Sclerosis, Multiple Sclerosis (MS) - Relapsing-remitting, Virtual Reality
- Trial name
- VRMS (NCT06987994)
- Testing
- control group( physical therapy), Experemental group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istinye University
Multiple Sclerosis
Effect of Cooling Vest in Multiple Sclerosis Patients
This study is prospective, randomized controlled trail that will be conducted to investigate the effect of cooling therapy on fatigue and gait in patient with multiple sclerosis(MS).
- Trial name
- NCT07064239
- Testing
- cooling vest, Aerobic exercises
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Multiple Sclerosis
Neurorehabilitation on Upper Limb and on Fatigue in Multiple Sclerosis
In Multiple Sclerosis the multiplicity of physical and psychological dysfunctions have been shown to exhibit a number of life-altering problems such as fatigue, limb weakness, alteration of upper extremity fine motor…
- Trial name
- NCT02960984
- Testing
- Task Oriented rehabilitation and aerobic training
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Fatigue, Multiple Sclerosis
Observational Study of the Effect of Ozanimod on Fatigue in Multiple Sclerosis Patients
Multi-center observational study to assess the short-term response of multiple sclerosis (MS) patients initiated on Ozanimod with respect to fatigue.
- Trial name
- NCT05319093
- Testing
- Ozanimod
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Brigham and Women's Hospital
Multiple Sclerosis
Waking Hypnosis in the Treatment of MS-related Fatigue
The proposed study is a single-center, single-blind three-group randomized (1:1:1) controlled trial (RCT) comparing two hypnosis interventions to waitlist control efficacy for MS-related fatigue.
- Trial name
- POWER-UP (NCT04429789)
- Testing
- Active-Alert Hypnosis, Traditional Hypnosis
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Washington
Multiple Sclerosis (MS) - Relapsing-remitting, Mediterranean Diet
Effect of Low Histamine-Based Modified Mediterranean Diet in Multiple Sclerosis
This randomized controlled trial will evaluate the effects of a low histamine-based modified Mediterranean diet in adults with relapsing-remitting multiple sclerosis (RRMS).
- Trial name
- HistaMed-MS (NCT07501520)
- Testing
- Low Histamine-Based Modified Mediterranean Diet, Traditional Mediterranean Diet
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Firat University
Sclerosis, Fatigue
Effects of Individualized Training to Reduce Fatigue in Patients With Newly and Advanced Diagnosed Multiple Sclerosis
Multiple sclerosis (MS) is a chronic autoimmune inflammatory disease of the central nervous system. It is characterized by complex and heterogeneous symptoms. Chronic fatigue is the most reported symptom in MS patients (80%).
- Trial name
- MovelySEP (NCT06201026)
- Testing
- Traditional exercise, Individualized exercise
- Where
- France
- Volunteers
- 96 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne