Clinical trials: Muscle; Fatigue
Healthy
Respiratory Muscle Fatigue at Different Breathing Modes
The study aims at investigating if time to respiratory muscle fatigue and metabolism are influenced by the pressure wave form mode applied during resistive breathing.
- Trial name
- NCT05393115
- Testing
- Square wave breathing
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Mental Fatigue, Fatigue
Effect of Ginko and Cistanche Against Fatigue Symptoms
To evaluate the efficacy of Nutrilite® ginkgo biloba cistanche tablets in relieving the symptoms of chronic fatigue syndrome(CFS), the investigators randomly recruit189 subjects with CFS, aged 35-60 yrs.
- Conditions
- Mental Fatigue, Fatigue, Chronic Fatigue Syndrome
- Trial name
- GkoCist (NCT02807649)
- Testing
- Experimental: Nutrilite® Low dose, Experimental: Nutrilite® High dose
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Access Business Group
Muscle Fatigue, Trapezius Muscle Strain
Short Interventions to Prevent Trapezius Muscle Fatigue in Computer Work
This study is expected to demonstrate that during experimental days of seated computer work sustained and focalized low-level muscle activity contributes to the development of long-lasting fatigue effects (and thus possible…
- Trial name
- NCT03863340
- Testing
- interruptions of work tasks
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Exercise-Induced Fatigue
Muscle Oxygenation and Autonomic Recovery After Repeated Sprint in Competitive Soccer Players
This study evaluates the acute and short-term recovery responses to repeated sprint exercise in competitive male soccer players.
- Trial name
- NCT07742163
- Testing
- 8 x 30 m Repeated Sprint Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Acute Muscle Damage Following Resistance Exercise
Acute Muscle Damage After Eccentric Quasi-Isometric Exercise of the Elbow Flexors
This study compared the acute muscle damage responses of the elbow flexor muscles following two types of resistance exercise: eccentric quasi-isometric (EQI) exercise and traditional eccentric (ECC) exercise.
- Trial name
- NCT07431879
- Testing
- Eccentric Quasi-Isometric Exercise, Traditional Eccentric Exercise
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chinese Culture University
Fibromyalgia
The Altered Immune Response to Exercise in Patients With Fibromyalgia Before and After a Mind-body Intervention
The purpose of this study is to compare two different exercise programs to see if there are differences after exercise in fibromyalgia (FM) symptoms and responses from the immune system.
- Trial name
- NCT03441997
- Testing
- Mind-body exercise, Light mobility exercises
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Post-COVID-19, Healthy Participants
Effects of Post-COVID-19 on Quadriceps Femoral Muscle-tendon Unit
The physiological/biomechanical characteristics related to muscle and tendon architecture and their possible relationship with the loss of muscle strength and fatigue in patients who were infected with COVID-19 are totally…
- Trial name
- NCT04961255
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Brasilia
Fatigue
BioSteel Supplementation and Performance
BioSteel Sports Drink (BSD), a proprietary blend of branched chain amino acids, taurine, and B vitamins, has increased its popularity among professional and amateur athletes.
- Trial name
- NCT02019316
- Testing
- BioSteel Sports Drink, Isoenergetic Control
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Western Ontario, Canada
Muscle Damage
Recovery Kinetics Following Eccentric Exercise
The aim of this study will be to investigate the recovery kinetics of neuromuscular fatigue, muscle microtrauma indicators, performance and oxidative stress factors after three different exercise induced muscle damage (EIMD)…
- Trial name
- NCT04733911
- Testing
- 75 eccentric contractions, 150 eccentric contractions, 300 eccentric contractions
- Where
- Greece
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Fatigue, Muscle
Feasibility Study of a Neuromuscular Fatigue Test and Associated Hemodynamic Responses: Application in Healthy Volunteers for Use in Patients with Chemotherapy-treated Breast Cancer
This cross-sectional and single-center study aims to progressively induce an increase in peripheral fatigue during successive efforts in healthy subjects.
- Conditions
- Fatigue, Muscle, Heart
- Trial name
- PROTECT-08A (NCT06775119)
- Testing
- Test of neuromuscular fatigue and associated hemodynamic responses
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Institut de cancérologie Strasbourg Europe
Primary Hyperparathyroidism
Gait and Balance Parameters Before and After Parathyroidectomy in Patients With Primary Hyperparathyroidism
This study will evaluate how Quadriceps Femoris muscle fatigue protocol affect the spatio-temporal gait parameters, gait symmetry and balance in individuals with primary hyperparathyroidism before and after parathyroidectomy.
- Trial name
- NCT03713671
- Testing
- gait analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Health Adult Subjects
Dose-response Effects of Dietary Nitrate on Running Time-to-exhaustion and Neuromuscular Fatigue: a Randomized Crossover Exploratory Pilot Study
Background: Dietary nitrate is a natural compound found in vegetables such as beetroot and leafy greens. Previous research suggests that consuming nitrate before exercise may improve endurance and physical performance.
- Trial name
- Nitrate TTE (NCT07735455)
- Testing
- Dietary Nitrate
- Where
- Spain
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Madrid
Fatigue
Role of Artificial Intelligence in Predicting Muscle Fatigue Using Virtual Reality Training
The goal of this observational predicted study is to predict muscle fatigue using a specific AI algorithm in healthy vs post Covid-19 infected individuals.
- Trial name
- NCT05813613
- Testing
- Squatting with the aid of Kynapsis Virtual Training apparatus.
- Where
- Lebanon
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Beirut Arab University
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
The Effect of Acupuncture Therapy on Cognitive Function in Post-COVID-19 Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Background of study: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a common sequela after SARS-CoV-2 infection(COVID-19). Cognitive dysfunction is one of the most common debilitating symptoms in ME/CFS.
- Trial name
- NCT07357688
- Testing
- Acupuncture
- Where
- 2 sites in China
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Xi Wu
Chronic Fatigue Syndrome, Myalgic Encephalomyelitis
The Norwegian Study of Chronic Fatigue Syndrome in Adolescents: Pathophysiology and Intervention Trial
The purpose of this study IS to explore the underlying pathophysiology of chronic fatigue syndrome (CFS) in adolescents, particularly focusing on genetics, infections/immunology, endocrinology, autonomic control and cognitions to…
- Trial name
- NorCAPITAL (NCT01040429)
- Testing
- Clonidine, Lactose capsula
- Where
- Norway
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Multiple Sclerosis, Remitting-Relapsing Multiple Sclerosis
Cognitive Performance, Sleep Disturbances and Fatigue in Multiple Sclerosis
Fatigue is a prevalent symptom in patients with multiple sclerosis (MS) and is associated with considerable impairment in quality of life as well as loss of occupational capacity.
- Conditions
- Multiple Sclerosis, Remitting-Relapsing Multiple Sclerosis, Primary Progressive Multiple Sclerosis, Secondary Progress Multiple Sclerosis
- Trial name
- NCT07426991
- Testing
- No Intervention: Observational Cohort
- Where
- 2 sites in Germany
- Volunteers
- 837 people, healthy volunteers welcome
- Sponsor
- Heinrich-Heine University, Duesseldorf
Heart Failure
Exercise Capacity and Fatigue in Heart Failure Patients With and Without Inspiratory Muscle Weakness
In patients with heart failure, diaphragm dysfunction contributes to decreased quality of life while simultaneously increasing morbidity and mortality.
- Trial name
- NCT06428227
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Gazi University
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Chronic Infections and Inflammation in ME/CFS: An Observational Study
CHIIME is a study of people who have myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). People who do not have this condition will also be enrolled.
- Trial name
- CHIIME (NCT07227441)
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Efficacy, Self, Fatigue; Muscle, Heart
Neuromodulation of the Autonomic Nervous System in Athletes
There are few studies in the literature that have evaluated the effects of using percutaneous stimulation of the auricular branch of the vagus nerve for sports purposes (to accelerate recovery after physical exertion).
- Conditions
- Efficacy, Self, Fatigue; Muscle, Heart, Fatigue, Mental, Fatigue; Combat
- Trial name
- NANSA (NCT06281795)
- Testing
- tVNS
- Where
- Russia
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Bakulev Scientific Center of Cardiovascular Surgery
Fibromyalgia, Force Measurement
Evaluation of Fingertip Precision Pinch Force in Fibromyalgia Patients
This study aims to evaluate the force used by fibromyalgia patients during a task compared to healthy volunteers and to evaluate its relationship with fatigue seen in these patients.
- Conditions
- Fibromyalgia, Force Measurement, Isokinetic, Muscle Strength
- Trial name
- NCT06825195
- Testing
- isokinetic muscle strength measurement, Minimum pinch force measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Dilara Ekici Zincirci