Clinical trials: Muscle Adaptation, open to volunteers
Collagen Supplementation
Influence of Specific Collagen Peptides on Training-Induced Metabolic and Biomechanical Adaptations of Skeletal Muscle
This study investigates whether taking daily collagen peptides, combined with long-term endurance or concurrent training can enhance running economy through muscle and/or tendon adaptations.
- Trial name
- NCT06689761
- Testing
- ColCT, ColET, PlaCT
- Where
- Austria
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Vienna
Fibromyalgia (FM)
Between Paws and Affections - Impact of Dog-Assisted Therapy in Fibromyalgia Patients
The purpose of this study is to evaluate the effectiveness and medium-term maintenance of a structured dog-assisted therapy (DAT) protocol, "Entre Patas e Afetos" (Between Paws and Affections), in reducing pain, anxiety and…
- Trial name
- IDAT26 (NCT07356206)
- Testing
- Behavioral: Dog Assisted Therapy (DAT - "Between Paws and Affections"), Behavioral: Psychoeducation and Relaxation without Dogs (Control)
- Where
- Portugal
- Volunteers
- 60 people
- Sponsor
- University of Minho
Athletic Performance, Soccer
The Effect of a Training Programme in the Variation of Fitness Parameters, Physiological, Hematological and Biochemical Indicators of Soccer Players During the Preseason Period
The goal of this study is to investigate the effects of varying friendly match-play exposure during the late pre-season on physiological, biochemical, and performance adaptations in soccer players.
- Conditions
- Athletic Performance, Soccer, Muscle Damage, Inflammation
- Trial name
- NCT07170930
- Testing
- Friendly Match-Play Exposure: extended vs. limited
- Where
- Greece
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Emmanouil D. Zacharakis
Fibromyalgia Syndrome
Validity, Reliability, and Clinical Correlates of Immersive Virtual Reality Adaptation of the Five Times Sit-to-stand Test and Timed up and go Tests in Women With Fibromyalgia Syndrome
Fibromyalgia syndrome (FMS) is a chronic rheumatic condition characterized by widespread pain, fatigue, and functional impairments that negatively affect physical activity levels, muscle strength, balance, and functional…
- Trial name
- NCT07381244
- Volunteers
- 51 people
- Sponsor
- Selcuk University
Sarcopenia
Morphological and Functional Biomarkers of Skeletal Muscle Adaptations in Sarcopenia
Sarcopenia is an age-related condition characterized by progressive loss of skeletal muscle mass, muscle strength, and physical performance.
- Trial name
- EXEDOS (NCT07692308)
- Testing
- Digitally delivered home-based exercise intervention, General physical activity recommendations
- Where
- Italy
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Hormone, Cardiovascular
Cardiometabolic and Hormonal Adaptations to 4-Month Zumba Training in Overweight/Obese Women
This study aims to evaluate the effects of a 4 month Zumba training program on cardiometabolic, hormonal, inflammatory, hepatic, renal, and functional parameters in overweight and obese women.
- Conditions
- Hormone, Cardiovascular, Obesity & Overweight
- Trial name
- NCT07264348
- Testing
- Zumba training
- Volunteers
- 73 people
- Sponsor
- High Institute of Sports and Physical Education of Kef
Stroke
Sensory Feedback and Hand Motor Adaptation
The following experiment will be conducted with 15 chronic stroke survivors and 15 control subjects. Subjects will perform hand movements in the virtual reality environment using a head-mounted display.
- Trial name
- NCT07598695
- Testing
- Visual ROM augmentation, Visual ROM reduction
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Catholic University of America
Obesity & Overweight
Long-term Adaptations of Skeletal Muscle After Hybrid Training
Obesity is a major challenge for public health and renders it imperative to reduce its prevalence. High intensity interval training (HIIT) is a form of exercise training that can efficiently induce weight loss in adults with…
- Trial name
- NCT07341711
- Testing
- Exercise training, Control group
- Where
- Greece
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
HFrEF - Heart Failure With Reduced Ejection Fraction, Cardiac Rehabilitation
Predictive Factors of Response to Phase II Cardiac Rehabilitation in Heart Failure With Reduced Ejection Fraction
Exercise intolerance, measured as peak oxygen consumption (VO₂peak) during exercise in patients with heart failure with reduced ejection fraction (HFrEF).
- Conditions
- HFrEF - Heart Failure With Reduced Ejection Fraction, Cardiac Rehabilitation, Exercise Training, Exercise Adaptations
- Trial name
- PrédicRéa (NCT07164911)
- Where
- France
- Volunteers
- 62 people
- Sponsor
- Centre Hospitalier de Corbie
Temporomandibular Disorders (TMDs), Kinesiophobia
The Italian Version of the Tampa Scale for Kinesiophobia for Temporomandibular Disorders (TSK-TMD)
This observational, cross-sectional study aims to translate, culturally adapt, and psychometrically validate the Italian version of the Tampa Scale for Kinesiophobia for Temporomandibular Disorders (TSK-TMD-ITA).
- Trial name
- TSK-TMD-ITA (NCT07750509)
- Volunteers
- 250 people
- Sponsor
- Alessandro Aquino
Muscle Inhibition, Knee Injury Simulation
Quadriceps Motor Unit Adaptation to Simulated Knee Injury
This study investigates how simulated knee injury-via artificial joint effusion or deafferentation-affects quadriceps motor unit behavior in healthy young adults.
- Trial name
- NCT06999057
- Testing
- Joint Effusion via 60 mL Sterile Saline, Intra-articular Lidocaine
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Prolonged Mechanical Ventilation, Ventilator Weaning
Effects of Mobilization Using a Powered Lower-limb Exoskeleton With Prolonged Mechanical Ventilation
This study aims to evaluate the effects of powered lower-limb exoskeleton-assisted training on lower limb strength, respiratory parameters, 28-day ventilator-free days, and length of hospital stay in patients with prolonged…
- Conditions
- Prolonged Mechanical Ventilation, Ventilator Weaning, Ventilator Dependent, Exoskeleton Device
- Trial name
- NCT07445035
- Testing
- lower-limb exoskeleton, Standard medical treatment
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Fu Jen Catholic University
Strength Training Adaptations
Effects of Traditional and Cluster Set Resistance Training on Muscle Strength, Hypertrophy, and Power
This study aims to compare the effects of traditional resistance training and two different cluster set configurations on muscle strength, muscle hypertrophy, and explosive performance.
- Trial name
- NCT07910188
- Testing
- Traditional Set Resistance Training, Three-Repetition Cluster Set Training, Six-Repetition Cluster Set Training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- GÜRKAN DİKER
Postpartum, Neuromuscular Adaptations
Postpartum Exercise Intervention
The postpartum period is associated with decreases in physical activity levels, muscular strength, muscular endurance, and pelvic floor muscle function, but little scientific evidence exists on how best to initiate and progress…
- Conditions
- Postpartum, Neuromuscular Adaptations, Abdominal Muscles, Pelvic Floor Dysfunctions
- Trial name
- NCT07613333
- Testing
- Progressive exercise, Active Straight Leg Raise Test, Active Straight Leg Raise Fatigue Task
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Carroll University
Obesity & Overweight, Childhood Obesity
Combined Inspiratory Muscle Training and Functional High-Intensity Interval Training in Boys With Obesity
Childhood obesity is associated with reduced cardiorespiratory fitness, impaired exercise tolerance, and altered respiratory mechanics.
- Trial name
- IMT and HIIT (NCT07810361)
- Testing
- Inspiratory Muscle Training, Functional High-Intensity Interval Training
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Gümüşhane Universıty
Dyslipidemia, Long-Distance Running
The Effects of Rosuvastatin on Running Training Adaptation and Safety
Statins lower low-density lipoprotein cholesterol (LDL-C) and help prevent atherosclerotic cardiovascular disease, but some users develop statin-associated muscle symptoms (SAMS) such as soreness, stiffness, weakness, or elevated…
- Conditions
- Dyslipidemia, Long-Distance Running, Endurance Training, Statin-Associated Muscle Symptoms
- Trial name
- NCT07401017
- Testing
- Rosuvastatin
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University WanFang Hospital
Resistance Exercise, Neuromuscular Adaptations
Comparison of the Effects of Free Weight and Machine-Based Exercises on Muscular Parameters
The aim of our study is to compare and investigate the effects of resistance exercises performed with free weights and those performed using machine systems on muscular parameters and neuromuscular control.
- Conditions
- Resistance Exercise, Neuromuscular Adaptations, Muscle, Adult
- Trial name
- NCT07495540
- Testing
- Machine-Based Resistance Exercise Group, Free Weight-Based Resistance Training Group
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Biruni University
Type 2 Diabetes Mellitus (T2DM), Sarcopenia
HMB Plus Vitamin D to Preserve Muscle in Older Adults Starting Semaglutide
This randomized, double-blind, placebo-controlled trial will evaluate whether daily calcium beta-hydroxy-beta-methylbutyrate (calcium-HMB) plus vitamin D3 preserves muscle mass, physical function, and resting metabolism in adults…
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Sarcopenia, Obesity, Muscle Loss
- Trial name
- PRESERVE-HMB (NCT07760948)
- Testing
- Calcium-HMB Plus Vitamin D3
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Vanderbilt University Medical Center