Clinical trials: Muscle Contracture
CLIFAHDD, Congenital Contractures of the Limbs and Face, Hypotonia, and Developmental Delay
Aprepitant for the Treatment of CLIFAHDD
There are no drug treatments for individuals with Congenital Contractures of the Limb and Face, Hypotonia, and Developmental Delay (CLIFAHDD), an ultra-rare and severe neurodevelopmental disease.
- Conditions
- CLIFAHDD, Congenital Contractures of the Limbs and Face, Hypotonia, and Developmental Delay, NALCN Channelopathy, Ataxia - Other
- Trial name
- NCT07845825
- Testing
- Aprepitant Powder for Oral Suspension
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Hamstring Contractures, Muscle Relaxation
Dynamic Stretching vs. Foam Rolling: Effects on Hamstring Flexibility and Muscle Oxygenation in Tight Hamstrings
Hamstring muscle flexibility plays a vital role in functional movement and in the prevention of injuries. Reduced flexibility of the hamstring muscles is common and can lead to biomechanical dysfunctions, a limited range of…
- Conditions
- Hamstring Contractures, Muscle Relaxation, Muscle Tightness
- Trial name
- NCT07024017
- Testing
- Foam roller, dynamic stretch
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Pelin Pişirici
Ankle Contracture, Critically Ill Intensive Care Unit Patients
Continuous Passive Motion to Prevent Ankle Contracture and Muscle Atrophy in Ventilated Patients
This clinical trial aims to evaluate whether continuous passive motion (CPM) can prevent ankle joint contracture and muscle atrophy in critically ill patients receiving mechanical ventilation in the ICU.
- Conditions
- Ankle Contracture, Critically Ill Intensive Care Unit Patients, Muscle Atrophy
- Trial name
- CPM-ICU (NCT07032051)
- Testing
- Continuous Passive Motion
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Joint Contracture, Mechanical Ventilation
Using Continuous Passive Motion to Prevent Ankle Problems in ICU Patients
The goal of this clinical trial is to learn if continuous passive motion (CPM) helps prevent ankle joint contracture and muscle loss in critically ill, mechanically ventilated ICU patients.
- Conditions
- Joint Contracture, Mechanical Ventilation, ICU-acquired Weakness, Critical Illness
- Trial name
- NCT06944431
- Testing
- Continuous Passive Motion (CPM)
- Where
- Taiwan
- Volunteers
- 12 people
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Upper Extremity Paresis, Muscle Contracture Upper Arm
Use of Surface Electromyography as a Tools to Predict Upper Extremity Recovery Function After Stroke
Hypothesis : Based on the framework and premises above, the hypothesis is formulated as follows: H0 : surface electromyography parameters cannot predicts upper extremity motor function recovery in stroke patients H1: surface…
- Conditions
- Upper Extremity Paresis, Muscle Contracture Upper Arm, Stroke
- Trial name
- NCT06574737
- Where
- Indonesia
- Volunteers
- 30 people
- Sponsor
- Universitas Padjadjaran
Contracture, Spasticity, Muscle
Effect of Cryoneurolysis on Pain in Patients With Hand Contracture.
Contracture which is defined as a limitation of the maximum passive range of motion due to changes in periarticular soft tissue can contributes to severe pain and increased disabilities.
- Trial name
- NCT06051656
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Vancouver Island Health Authority
Hamstring Contractures, Muscle Tightness
Immediate and 24-hour Effects of HyperVolt, Body Tempering, and Cupping Compared to Stretching on Hamstring Flexibility
The purpose of this study is to compare the effects of the HyperVolt percussive massage device, body tempering, and dry cupping to static stretching of the hamstrings of healthy adults aged 18-39 years on the active knee…
- Trial name
- NCT05793242
- Testing
- Hypervolt, Body Tempering, Dry cupping
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Cerebral Palsy, Muscle Contracture
The Muscle in Cerebral Palsy; Sarcomere Length in Vivo and Microscopic Characterization of Biopsies.
Cerebral palsy (CP) is a motor impairment due to a brain malformation or a brain lesion before the age of two. Spasticity, hypertonus in flexor muscles, dyscoordination and an impaired sensorimotor control are cardinal symptoms.
- Conditions
- Cerebral Palsy, Muscle Contracture, Spasticity, Muscle
- Trial name
- CPMuscleSL (NCT05518565)
- Testing
- No intervention
- Where
- 3 sites in Sweden
- Volunteers
- 150 people
- Sponsor
- Eva Ponten
Cerebral Palsy, Muscle
How Are the Muscles Affected in Cerebral Palsy? A Study of Muscle Biopsies Taken During Orthopaedic Surgery.
Cerebral palsy (CP) is a motor disorder caused by an injury to the immature brain. Even though the brain damage does not change, children with CP will have progressively weaker, shorter and stiffer muscles that will lead to…
- Conditions
- Cerebral Palsy, Muscle, Muscle Contracture, Muscle Spasticity
- Trial name
- CPTDBiopsy (NCT05506228)
- Testing
- No intervention
- Where
- Sweden
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Eva Ponten
Neck Muscle Issue, Sternocleidomastoid; Contracture
Functional and Morphological Characteristics of Neck Muscles in Acrobatic Skydivers
An observational cohort study, following the Strengthening the Reporting of Observational Studies in Epidemiology(STROBE) guidelines.
- Conditions
- Neck Muscle Issue, Sternocleidomastoid; Contracture, Deltoid Muscle Strain
- Trial name
- NCT04784195
- Testing
- Observation
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Skin Laxity, Muscle Contracture
Evaluation of the Immediate Effect and Safety of DMA™ Novel Muscle Stimulation Technology
A total of at least 15 and up to 17 healthy subjects at a single site, aged 25-45 years old, who wish to receive a lifting effect and improved muscle definition, will be included in the study.
- Trial name
- NCT04296201
- Testing
- DMA treatment
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Lumenis Be Ltd.
Ankle Osteoarthritis, Knee Osteoarthritis
Gait Asymmetry Assessed Using Portable Gait Analysis System
To date, detailed analysis of movement patterns in orthopaedic conditions are mainly performed in research projects. Because these tests are time consuming, they are not feasible in clinical routine or in standard examinations.
- Conditions
- Ankle Osteoarthritis, Knee Osteoarthritis, Hip Osteoarthritis, Lumbar Spine Stenosis
- Trial name
- Asymmetry (NCT02489188)
- Testing
- arthroplasty, manual therapy, lumbar spinal stenosis decompression
- Where
- Switzerland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Duchenne Muscular Dystrophy, Muscle Strength
Effect of Muscle Strength on Hamstring Flexibility in Children With Duchenne Muscular Dystrophy
Investigator researched that the effect of trunk and lower extremity muscle strength on hamstring flexibility in children with Duchenne Muscular Dystrophy.
- Conditions
- Duchenne Muscular Dystrophy, Muscle Strength, Lower Extremity, Hamstring Contractures
- Trial name
- NCT03589573
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hacettepe University
Contracture of Muscle, Thigh, Muscle Rigidity
Differents Intensities of Passive Stretching on ROM, Neuromuscular and Performance in Soccer Players: A Blinded RCT
Intensity is a "qualitative" variable of a muscle stretching protocol, which is very little studied due to its inherent characteristic of the individual being stretched.
- Conditions
- Contracture of Muscle, Thigh, Muscle Rigidity, Strain of Hamstring Muscle (Disorder)
- Trial name
- NCT03150563
- Testing
- Passive static stretch
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio Grande do Norte
Contracture of Muscle, Thigh
The Effect of Reducing Soreness in Marathon Runners
Delayed onset muscle soreness is defined as the sensition of pain and discomfort in skeletal muscles that occurs after eccentric muscle actions or strenuous exercise like a marathon.
- Trial name
- NCT01512082
- Testing
- Pulsed electromagnetic field devices
- Where
- Denmark
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Northern Orthopaedic Division, Denmark
Stroke, Muscle Spasticity
Early Use of Botulinum Toxin in Spasticity Post Stroke.
Patients who survive a stroke are often left with an arm that cannot be used. One reason for this is that the muscles affected by the stroke become overactive. This is known as spasticity.
- Conditions
- Stroke, Muscle Spasticity, Contracture
- Trial name
- EUBoSS (NCT01882556)
- Testing
- onabotulinumtoxinA
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- Sandwell & West Birmingham Hospitals NHS Trust