Clinical trials: Muscle Disorders
SCI - Spinal Cord Injury, Spastic
"Validated Language Transfer of the Spinal Cord Injury-Spasticity Evaluation Tool to German Language"
To better depict the full range of spasticity after Spinal Cord Injury (SCI) there is a need to take into account the patients perspective and their experiences during daily life.
- Trial name
- SCI-SETde (NCT05022095)
- Testing
- Questionnaires
- Where
- Switzerland
- Volunteers
- 65 people
- Sponsor
- Swiss Paraplegic Research, Nottwil
Type 1 Diabetes (Juvenile Onset), Type 1 Diabetes
Type 1 Diabetes Autonomic and Vascular Function
The goal of this clinical trial is to investigate the autonomic and vascular function in men and women with Type 1 diabetes. The main questions it aims to answer are: 1.
- Conditions
- Type 1 Diabetes (Juvenile Onset), Type 1 Diabetes, Diabetes, Autoimmune
- Trial name
- NCT06786546
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Hip Pain Chronic, Impingement Syndrome
Correlation of Ultrasound and MRI Measurements of Quadratus Femoris Thickness and Ischiofemoral Distance in Clinically and Radiologically Diagnosed Ischiofemoral Impingement
The goal of this observational study is to evaluate the correlation between ultrasound measurements of quadratus femoris muscle thickness and ischiofemoral distance, as well as clinical parameters, with MRI measurements in…
- Trial name
- MRI USG (NCT07198646)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Kutay Can ÇAMLICA
Generalized Anxiety Disorder (GAD)
Inspiratory Muscle Training and Diaphragmatic Breathing in GAD
This study will compare inspiratory muscle training and diaphragmatic breathing exercises in individuals with generalized anxiety disorder (GAD).
- Trial name
- NCT07913503
- Testing
- Inspiratory Muscle Training, Diaphragmatic Breathing Exercises, Progressive Muscle Relaxation
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Saglik Bilimleri Universitesi
Glucose Intolerance
Effect of Feeding Frequency on Glucose and Insulin Metabolism and Substrate Partitioning in Impaired Glucose Tolerant (IGT) Men
The purpose of this study is to determine the effect of feeding frequency on glucose and insulin metabolism and substrate partitioning in impaired glucose tolerant (IGT) men.
- Trial name
- NCT01456754
- Testing
- low feeding frequency (3x), High feeding frequency (14x)
- Where
- Netherlands
- Volunteers
- 11 people
- Sponsor
- Maastricht University Medical Center
Fibromyalgia, Vestibular Disease
Effectiveness of Vestibular Rehabilitation for Improving Health Status in Patients With Fibromyalgia
The purpose of this study is to analyze the effectiveness of Vestibular Rehabilitation for improving balance and quality of life of patients with Fibromyalgia Syndrome (SFM).
- Conditions
- Fibromyalgia, Vestibular Disease, Postural Balance, Vestibular Rehabilitation
- Trial name
- NCT05300529
- Testing
- Vestibular Rehabilitation Exercises, Conventional Rehabilitation exercises
- Where
- Spain
- Volunteers
- 35 people
- Sponsor
- University of Jaén
Piriformis Syndrome
Effects of MET and MFR on Piriformis Syndrome
The aim of this study is to comparatively evaluate the effects of two different manual therapy approaches, Muscle Energy Technique (MET) and Myofascial Release Technique (MFR), on pain threshold, muscle activation patterns, and…
- Trial name
- NCT07769203
- Testing
- Muscle Energy Technique, Myofascial Release Technique, Conventional Physical Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Igdir University
Muscular Dystrophy, Facioscapulohumeral
Study of SRP-1001 in Adult and Adolescent Participants With Facioscapulohumeral Muscular Dystrophy Type 1
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics of SRP-1001 in participants with facioscapulohumeral muscular dystrophy Type 1 (FSHD1).
- Trial name
- NCT06131983
- Testing
- SRP-1001 for Injection
- Where
- 16 sites in Australia, Canada and 5 more
- Volunteers
- 60 people
- Sponsor
- Sarepta Therapeutics, Inc.
Mild Cognitive Impairment
The Impact of Physical Exercise on Working Memory in Elderly People With Mild Cognitive Impairment
Age-related cognitive decline has evolved into a global public health concern, with deteriorated executive function serving as its predominant manifestation.
- Trial name
- NCT07644156
- Testing
- Resistance band exercise intervention, Brisk walking intervention, Eight-Section brocade exercise intervention
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Shanghai University of Sport
Major Depression, Fibromyalgia
A Pilot Study of TMS Effects on Pain and Depression in Patients With Fibromyalgia
In this pilot study, the PI proposes to include 20 African American participants with Fibromyalgia to explore the effect of r TMS on pain and depressive symptoms.
- Trial name
- TMS (NCT00523302)
- Testing
- Active TMS
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical University of South Carolina
Urinary Incontinence, Pelvic Floor Muscle Weakness
The Effects of Pelvic Floor Muscle Training Combined With Otago Exercises in Elderly People With Incontinence
Pelvic floor muscle weakness is one of the most important causes of incontinence. There are many studies supporting that pelvic floor muscle training prevents incontinence and reduces symptom severity, and with A level of…
- Conditions
- Urinary Incontinence, Pelvic Floor Muscle Weakness, Muscle Weakness
- Trial name
- NCT06331039
- Testing
- PFMT, PFMT+Otago
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
Obesity (BMI > 35)
Preserving Muscle Mass During Incretin-Induced Weight Loss
Treatment with incretin-based obesity medications leads to clinically meaningful weight loss and reduced cardiometabolic risk. However, the weight lost includes not only adipose tissue but also skeletal muscle, which may impair…
- Trial name
- INCRETraIN (NCT07761923)
- Testing
- Unilateral Resistance Training
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Karolinska Institutet
Sarcopenia, Sarcopenic Obesity
Effects of Sarcopenia on General Health Status in Elderly: a Population-based Study
This is a observational study, that aimed to determine the prevalence of sarcopenia using European Wording Group on Sarcopenia in Older People (EWGSOP) algorithm in a general elderly population in Algarve region (Portugal).
- Conditions
- Sarcopenia, Sarcopenic Obesity, Frailty
- Trial name
- NCT05918159
- Testing
- Sarcopenia Assessment
- Where
- Portugal
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Universidade do Algarve
Obesity, Compensated Cirrhosis
OPTIMIzing muScle Preservation in paTients wIth Cirrhosis
Patients with obesity and cirrhosis benefit from weight loss but are prone to sarcopenia (loss of muscle mass, strength, and function).
- Conditions
- Obesity, Compensated Cirrhosis, Sarcopenia
- Trial name
- OPTIMISTIC (NCT05367596)
- Testing
- Continuous Energy Restriction (CER), Alternate Day Modified Fasting (ADMF), Group Health Education Sessions
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Kansas Medical Center
Temporomandibular Joint Disorders
The Effect of Piroxicam Addition During Arthrocentesis on Mouth Opening and Postoperative Pain
TMDs is an ancient condition discovered thousands of years ago. Historians state that the ancient Egyptians were the first who managed TMDs. They manually treated joint dislocation by away similar to ours nowadays.
- Trial name
- NCT06508203
- Testing
- arthrocentesis with lactate ringer only, arthrocentesis with lactate ringer followed by injection with piroxicam 2 ml (40mg)
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Chronic Pain, Pain, Chronic
Virtual Reality - A New Vision on Pain
The purpose of the project is to investigate if the use of virtual reality (VR) technology with pre-programmed proprietary software can provide better treatment for patients with long-term pain conditions.
- Conditions
- Chronic Pain, Pain, Chronic, Musculoskeletal Disorder, Musculoskeletal Pain
- Trial name
- VROP (NCT06045741)
- Where
- Norway
- Volunteers
- 33 people
- Sponsor
- Sykehuset i Vestfold HF
Insulin Sensitivity, Glucose Metabolism Disorders
Bisphenol A and Muscle Insulin Sensitivity
This study examine oral bisphenol A consumption on muscle insulin sensitivity and hepatic glucose suppression. Half of the participants will receive a diet plus BPA and the other half will receive a diet plus no bisphenol A.
- Conditions
- Insulin Sensitivity, Glucose Metabolism Disorders, Microtia
- Trial name
- NCT03771066
- Testing
- bisphenol A
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- California Polytechnic State University-San Luis Obispo
Chronic Shoulder Pain
Adduction and Infraspinatus Activity in Shoulder Pain
The goal of this randomized crossover trial is to determine whether different levels of shoulder adduction pressure during an external rotation exercise change shoulder muscle activity in adults with chronic shoulder pain and…
- Trial name
- ISADER (NCT07765056)
- Testing
- Shoulder External Rotation With 0 mmHg Adduction Pressure, Shoulder External Rotation With 5 mmHg Adduction Pressure, Shoulder External Rotation With 10 mmHg Adduction Pressure
- Where
- Chile
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Universidad de La Frontera
Cervicogenic Headache
Deep Neck Flexors Training Versus Muscle Energy Technique on Cervicogenic Headache
Aim of this study is to compare the effects of deep neck flexors stretching versus muscles energy technique on pain, cervical range of motion, sleep disturbance and cervical spine posture in patients with Cervicogenic headache…
- Trial name
- NCT05754931
- Testing
- Deep neck flexors training + Conventional therapy, Muscles energy techniques + conventional therapy
- Where
- Pakistan
- Volunteers
- 28 people
- Sponsor
- Riphah International University
Chronic Fatigue Syndrome/ Myalgic Encephalitis (CFS/ME)
B-lymphocyte Depletion Using Rituximab in Chronic Fatigue Syndrome/ Myalgic Encephalopathy (CFS/ME). A Randomized Phase-III Study.
The hypothesis is that a subgroup of patients with Chronic Fatigue Syndrome/ Myalgic Encephalopathy (CFS/ME) have a chronically activated immune system and may benefit from B-lymphocyte treatment using the monoclonal anti-CD20…
- Trial name
- RituxME (NCT02229942)
- Testing
- Rituximab
- Where
- 5 sites in Norway
- Volunteers
- 151 people
- Sponsor
- Haukeland University Hospital
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