Clinical trials: Muscle Disorders
Chronic Pain, Musculoskeletal Pain
Equipping Patients Using Interventions for Pain and Depression
This project is part of the NIH Helping to End Addiction Long-term (HEAL) initiative (https://heal.nih.gov/). This randomized controlled trial (RCT) is phase 2 of a two-phase, 5-year project with the overarching goal of testing a…
- Conditions
- Chronic Pain, Musculoskeletal Pain, Depression, Health Equity
- Trial name
- EQUIPD (NCT06500780)
- Testing
- Coaching and Decision Aid
- Where
- United States
- Volunteers
- 304 people
- Sponsor
- Indiana University
Osteoarthitis, Fibromyalgia
Screening Anxiety and Depression Among Patients with Chronic Musculoskeletal Pain Within Physiotherapy Practices
This study will investigate whether physiotherapists can accurately identify symptoms of anxiety and of depression in patients with chronic musculoskeletal pain (primary aim).
- Conditions
- Osteoarthitis, Fibromyalgia, Rheumatoid Arthritis (RA, Low Back Pain
- Trial name
- NCT06785883
- Where
- Belgium
- Volunteers
- 750 people
- Sponsor
- KU Leuven
Parkinson Disease
Respiratory Functions in Parkinson's Disease
The aim is to examine respiratory functions, inspiratory muscle strength, respiratory function, physical fitness and aerobic capacity in Parkinson's disease patients.
- Trial name
- NCT07010783
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ankara University
Temporomandibular Disorder, Adolescent Behavior
Parafunctional Habits and Temporomandibular Disorder in Adolescents
The disorders that affect the temporomandibular joint (TMJ) are responsible for the diverse symptoms. Objective: To evaluate whether or not the relationship between signs or symptoms of TMD and presence of harmful habits.
- Trial name
- NCT01331031
- Where
- Brazil
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Aging, Healthy Aging
Biological Effects in Consumers of Resveratrol-enriched Wine
The objective of this clinical trial is to compare the health conditions of the participating population before and after an intervention with Resveratrol enriched wine. The main questions it aims to answer are: 1.
- Conditions
- Aging, Healthy Aging, Sarcopenia, Obesity
- Trial name
- NCT05981053
- Testing
- Wine enriched with Resveratrol
- Where
- Argentina
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- PINER Pastor Manfredi Winery
Stroke, Urinary Incontinence
Effect of Pelvic Floor Muscle Training in Stroke
Aim: To evaluate the long term effect of pelvic floor muscle training in women with urinary incontinence after ischemic stroke measured by quality of life paramters.
- Trial name
- NCT00258037
- Testing
- Pelvic Floor Muscle training
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Glostrup University Hospital, Copenhagen
Myofascial Pain Syndromes, Low Back Pain
Radial Extracorporeal Shock Wave Treatment (rESWT) of Myofascial Pain Syndrome in Low Back Pain
The purpose of this study is to evaluate the efficacy of treatment of radial shockwave in myofascial pain syndrome in the lumbar region compared to placebo through questionnaires and imaging exams.
- Conditions
- Myofascial Pain Syndromes, Low Back Pain, Lumbago
- Trial name
- NCT01835795
- Testing
- Swiss DolorClast® CLASSIC applicator
- Where
- Brazil
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Musculoskeletal Pain
Transcultural Adaptation and Validation to Spanish of the OSPRO Questionnaires
Clinical guidelines for managing musculoskeletal pain recommend first, assessing and identifying any signs of severe physical conditions (i.e."red flags") and then, asessing the psychosocial prognostic factors of poor outcomes…
- Trial name
- SpanishOSPRO (NCT05869695)
- Testing
- OSPRO-ROS Questionnaire, OSPRO-YF Questionnaire
- Where
- 2 sites in Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Distal Urethral Cancer, Proximal Urethral Cancer
Gemcitabine Hydrochloride and Cisplatin Before Surgery in Treating Patients With Muscle Invasive Bladder Cancer
The purpose of this research study is to find out what effects, good and/or bad, dose-dense (every 14 days) chemotherapy with gemcitabine (gemcitabine hydrochloride) and cisplatin given before surgery have on patients and their…
- Conditions
- Distal Urethral Cancer, Proximal Urethral Cancer, Squamous Cell Carcinoma of the Bladder, Stage II Bladder Cancer
- Trial name
- NCT01611662
- Testing
- gemcitabine hydrochloride, cisplatin, therapeutic conventional surgery
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- Fox Chase Cancer Center
Chronic Fatigue Syndrome
Pacing Activity Self-management for Patients With Chronic Fatigue Syndrome
Given the lack of evidence in support of pacing self-management for patients with chronic fatigue syndrome (CFS), it is examined whether physical behavior and health status of patients with CFS improve in response to a pacing…
- Trial name
- NCT01512342
- Testing
- Pacing, relaxation therapy
- Where
- Belgium
- Volunteers
- 33 people
- Sponsor
- Vrije Universiteit Brussel
Temporomandibular Joint Disorders
Effect of Mask Use on Jaw Functionality
Due to COVID-19 pandemic the use of masks has been made mandatory to prevent contagion. Individuals concluded that the use of masks has a negative effect on temporomandibular joint functions.
- Trial name
- NCT06103851
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Severe Sepsis, Respiratory Failure
Muscle Atrophy in Patients With Severe Sepsis
This study is being done to help determine whether patients with severe sepsis (overwhelming inflammation in the body as a result of an infection) lose muscle and become weak more rapidly than patients with other severe…
- Trial name
- NCT01717651
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Ohio State University
Fibromyalgia Syndrome
Effectiveness of Group Psychotherapy in Patients With Fibromyalgia Syndrome
The hypothesis of the study is that group therapy in fibromyalgia patients can provide significant improvement in pain, fatigue, anxiety and depression levels and emotional expressions.
- Trial name
- NCT04517929
- Testing
- Group Psychotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Ege University
Congenital Myotonic Dystrophy
Safety and Efficacy of Tideglusib in Congenital or Childhood Onset Myotonic Dystrophy
This is an open-label phase 2/3 study for individuals with Congenital Myotonic Dystrophy (Congenital DM1) who participated in the preceding AMO-02-MD-2-003 study or individuals with either Congenital or Childhood Onset DM1 who…
- Trial name
- REACH CDM X (NCT05004129)
- Testing
- Tideglusib
- Where
- 14 sites in United States, Australia and 2 more
- Volunteers
- 76 people
- Sponsor
- AMO Pharma Limited
Stroke
Effects of Whole Body Vibration in People With Chronic Stroke
The overall aim of the proposed study is to determine whether whole body vibration is beneficial in promoting bone health, physical fitness and neuromotor performance in patients with chronic stroke.
- Trial name
- NCT00937339
- Testing
- Whole body vibration therapy, Exercise on the vibration platform with the device turned off
- Where
- China
- Volunteers
- 82 people
- Sponsor
- The Hong Kong Polytechnic University
Spinal Muscular Atrophy (SMA)
A Study of the Safety and Preliminary Efficacy of NKG001 in Pediatric Patients With Type 1 or Type 2 Spinal Muscular Atrophy
This study is a single-center, open-label, single-arm, non-randomized, single-dose, dose-escalation investigator-initiated trial (IIT) designed to evaluate the safety, tolerability, and preliminary efficacy of NKG001 Injection…
- Trial name
- NCT07617779
- Testing
- NKG001
- Where
- China
- Volunteers
- 21 people
- Sponsor
- Nikegen Pharmaceutical (Hangzhou) Company Limited
Locally Advanced Rectal Cancer (LARC)
AI-Based Prediction of Pathological Response in Rectal Cancer Patients Receiving Total Neoadjuvant Therapy
This study aims to better understand how body composition, inflammation, and nutrition affect how rectal cancer responds to treatment.
- Trial name
- CINR-AI (NCT07049627)
- Testing
- Total Neoadjuvant Therapy (TNT)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Ankara Etlik City Hospital
Mild Cognitive Impairment (MCI)
Effect of Inspiratory Muscle Training in Cognition
The goal of this clinical trial is to examine the effect of a respiratory muscle strengthening program on the cognitive and physical functioning of patients with neurocognitive disorders (Mild Cognitive Impairment) or those…
- Trial name
- NCT07146373
- Testing
- Inspiratoty Muscle training, Usual Care
- Where
- Greece
- Volunteers
- 76 people
- Sponsor
- University of West Attica
Spasticity, Muscle, Cerebral Palsy
Effect of Session Frequency of rESWT on Gastrocnemius Muscle Spasticity in Children With Spastic Type Cerebral Palsy
Spasticity, defined as a velocity dependent increase in tonic stretch reflexes, is one of the most prominent motor problems that occur in patients with cerebral palsy (CP).
- Conditions
- Spasticity, Muscle, Cerebral Palsy, Child; Spastic
- Trial name
- NCT04574622
- Testing
- radial Extracorporeal Shockwave Therapy
- Where
- Indonesia
- Volunteers
- 14 people
- Sponsor
- Rizky Kusuma Wardhani
Ankle Contracture, Critically Ill Intensive Care Unit Patients
Continuous Passive Motion to Prevent Ankle Contracture and Muscle Atrophy in Ventilated Patients
This clinical trial aims to evaluate whether continuous passive motion (CPM) can prevent ankle joint contracture and muscle atrophy in critically ill patients receiving mechanical ventilation in the ICU.
- Conditions
- Ankle Contracture, Critically Ill Intensive Care Unit Patients, Muscle Atrophy
- Trial name
- CPM-ICU (NCT07032051)
- Testing
- Continuous Passive Motion
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
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