Clinical trials: Muscle Dysfunction
Amyotrophic Lateral Sclerosis (ALS), Myasthenia Gravis
Innovative Measures of Speech and Swallowing Dysfunction in Neurological Disorders
This study is evaluating the use of two painless, non-invasive technologies in the assessment of muscle health over time in both healthy volunteers and patients who have diseases that affect the nervous system.
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Myasthenia Gravis, Myopathies, Stroke
- Trial name
- QUESST (NCT02118805)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Exercise-induced Myocardial Damage, Right Ventricular Diastolic Dysfunction
Effects of Exogenous Ketones on Acute Changes and Recovery of the Heart Muscle After Intense Exercise.
It is well known that scar tissue on the heart muscle can cause (life-threatening) arrhythmias. However, the exact cause of this scar tissue is not entirely clear.
- Trial name
- NCT06715748
- Testing
- Ketone Monoester (KE)
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Jessa Hospital
Healthy Volunteers, Skeletal Muscle
Device Evaluating the Muscular Functional Age
The CHRONOS project aims to provide a device to detect earlier the motor decline, by developing a precise quantitative device measuring "Motor Functional Age" (MFA) of young, middle-aged and old people, thus preventing future…
- Trial name
- CHRONOS (NCT03560648)
- Testing
- High definition surface electromyography combined with accelerometer
- Where
- France
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Neck Pain, Low Back Pain
Study to Demonstrate That Muscle Pattern Recognition (MPR) is an Effective Evaluation Tool for Musculoskeletal Neck or Back Pain
The investigators hypothesize that non able-bodied participants with reported acute, sub-acute, or chronic symptoms of neck or back pain of a musculoskeletal origin will have magnetic resonance imaging (MRI), X-ray and blood…
- Trial name
- NCT00134225
- Testing
- Muscle Pattern Recognition (MPR)
- Where
- 4 sites in United States, Canada
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- iTech Medical, Inc.
Abdominal Hypertension, Abdominal Compartment Syndrome
Updated Abdominal Compartment Society Consensus Definitions
An international team of experts is working on a project called updated WSACS consensus definitions. The goals of this study are to: 1. To generate expert consensus on the definitions and classification of IAH and ACS. 2.
- Trial name
- WSACS (NCT07563842)
- Testing
- Delphi study
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical University of Lublin
Hypertension, Atherosclerosis
Age-Related Changes in Body Composition
Background: Advancing age is associated with greater risk of heart disease. High blood pressure and hardening of the arteries also have more complications with age.
- Trial name
- NCT01517113
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Abnormally Decreased Muscle Contraction
Abdominal Wall Evaluation in Low Back Pain
The purpose of this study was to evaluate feed-forward contraction of the transversus abdominis and thickness of the transversus abdominis, obliquus internus, and obliquus externus during calm and standardized respiration in low…
- Trial name
- NCT01488760
- Where
- Brazil
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Mild Cognitive Impairment
Effects of Alpha-lactalbumin Intake on Metabolic and Cognitive Functions in Elderly
Aging modifies the metabolic pathway of the neurotransmitter serotonin by reducing the synthesis rate and increasing the breakdown rate of serotonin, possibly related to the observed enhanced sensitivity of the serotonergic…
- Trial name
- NCT02082418
- Testing
- Alpha-lactalbumin, Whey, Casein
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Upper Cross Syndrome, Temporomandibular Disorder (TMD)
Upper Cross Syndrome and Temporomandibular Dysfunction in University Students
This cross-sectional observational study aims to investigate the relationship between Upper Cross Syndrome (UCS), a postural imbalance characterized by forward head posture and rounded shoulders, and Temporomandibular Disorder…
- Trial name
- UCS-TMD (NCT07456748)
- Testing
- No Intervention: Observational Cohort
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Sacroiliac Dysfunction
Global Changes Associated With Sacroiliac Joint Dysfunction
Summary Sacroiliac joint dysfunction (ASI) is an alteration in the normal biomechanics of the joint, which leads to hypomobility or hypermobility of that joint.
- Trial name
- GCASID (NCT06687148)
- Testing
- Manual manipulation
- Where
- Portugal
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Aveiro University
Autism Spectrum Disorder, Temporomandibular Joint Disorders
Balance, TMJ, Social Adaptive Assessment in Individuals With Autism Spectrum Disorder
The aim of our study is to evaluate temporomandibular joint (TMJ), cervical posture, balance, dual-task performance, and social adaptation skills in individuals with autism.
- Conditions
- Autism Spectrum Disorder, Temporomandibular Joint Disorders, Postural; Defect
- Trial name
- NCT06721104
- Testing
- Dual Task, Functional Balance, Social Adaptation Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Rheumatoid Arthritis, Insulin Resistance
Skeletal Muscle Dysfunction in Rheumatoid Arthritis (RA)
Muscle strength helps determine a person's quality of life and functional independence. Patients with rheumatoid arthritis often suffer from muscle weakness and a pre-diabetic condition called insulin resistance.
- Trial name
- NCT02535832
- Testing
- Pioglitazone
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Massage, Inflammatory Response
Comparison of Different Forms of Recovery on the Functionality After Physical Exercise
Delayed onset muscle soreness (DOMS) and decrease of musculoskeletal function are due to high intensity training and / or sports activities. These occur due to micro lesions of muscle tissue resulting in nociceptor sensitization.
- Conditions
- Massage, Inflammatory Response, Muscle, Skeletal, Cryotherapy Effect
- Trial name
- NCT04201977
- Testing
- Foam Roller Recovery, Active recovery, Immersion in cold water
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Santa Maria
Sexual Dysfunction, Postmenopausal Symptoms
Examination of the Effects of Pelvic Floor Exercises on Vaginal and Sexual Health in Postmenopausal Women.
The purpose of this study; To investigate the effects of pelvic floor muscle exercises on vaginal and sexual health in postmenopausal women.
- Conditions
- Sexual Dysfunction, Postmenopausal Symptoms, Pelvic Floor Muscle Weakness
- Trial name
- NCT06294197
- Testing
- Pelvic Floor Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hatice Gulsah Kurne
Temporomandibular Joint Dysfunction Syndrome
Respiratory Functions and Respiratory Muscle Strength in Patients With Temporomandibular Joint Dysfunction
In our study, it was aimed to evaluate respiratory functions and respiratory muscle strength in patients diagnosed with temporomandibular dysfunction (TMD) and to compare them with healthy individuals.
- Trial name
- NCT05271396
- Testing
- Clinical Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Halic University
Sex Disorders
The Effect of 5-Alpha Reductase on Testosterone in Men
The enzyme 5-alpha reductase is present in small amounts in muscle and converts testosterone to dihydrotestosterone (DHT). Testosterone affects lean body tissue, muscle size, muscle strength, and sexual function in men.
- Trial name
- NCT00070733
- Testing
- testosterone enanthate, duastride
- Where
- United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Musculoskeletal Pain, Musculoskeletal Strain
Surgeon Ergonomics in Robotic-assisted Laparoscopic Vs Standard Laparoscopic Surgery
Musculoskeletal injuries amongst surgeons are prevalent. This project will determine whether Robotic-assisted Laparoscopic surgery (RALS) offers superior benefits to surgeon's musculoskeletal health than standard laparoscopic…
- Conditions
- Musculoskeletal Pain, Musculoskeletal Strain, Fatigue; Muscle, Heart, Cognitive Impairment
- Trial name
- MURALS (NCT04477746)
- Where
- 2 sites in United Kingdom
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Lancaster University
Sacroiliac Disorder
Muscle Energy Technique on Sacroiliac Dysfunction
Sacroiliac pain is a huge problem in women during pregnancy and postpartum period. Muscle energy technique has potential effect in decreasing the pain and disability
- Trial name
- NCT05088837
- Testing
- muscle energy technique, ice and heat packs
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Temporomandibular Joint Disorders, Temporomandibular Sprain
Intra-articular Magnesium Sulfate for Tmj Dysfunction
mixing the magnesium sulfate with dextrose for management of tmj pain will be studied using intra-articular injection of the solution
- Trial name
- NCT03675659
- Testing
- intra-articular injection
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Myofascial Dysfunction
Immediate Effects of Upper Thoracic Manipulation on Skin Surface Temperature of T3 Vertebral Region and Biceps Brachii Muscle
The aim of the present study was to assess the immediate effects of upper thoracic manipulation on skin surface temperature in the region of the T3 vertebra and biceps brachii muscle in healthy women.
- Trial name
- NCT01872676
- Testing
- Spine manipulation
- Where
- Brazil
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Universidade Metodista de Piracicaba