Clinical trials: Muscle Dysfunction
Pelvic Floor Dysfunction, Pelvic Floor Muscle Weakness
Ultrasound and Electromyography Biofeedback for Pelvic Floor Muscle Training
This study aims to investigate the factors influencing adherence to pelvic floor muscle training (PFMT) devices among patients with pelvic floor dysfunction (PFD) through structured questionnaires, while simultaneously comparing…
- Trial name
- NCT07243028
- Testing
- Ultrasound Biofeedback Device, Manometer Biofeedback Device
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- National Cheng-Kung University Hospital
Sex Disorders
The Effect of 5-Alpha Reductase on Testosterone in Men
The enzyme 5-alpha reductase is present in small amounts in muscle and converts testosterone to dihydrotestosterone (DHT). Testosterone affects lean body tissue, muscle size, muscle strength, and sexual function in men.
- Trial name
- NCT00070733
- Testing
- testosterone enanthate, duastride
- Where
- United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Myotonic Dystrophy Type 2, Myotonic Dystrophy Type 1
Brain Structure and Clinical Endpoints in Myotonic Dystrophy Type 2
Nearly two-third of patients with myotonic dystrophy type 2 (DM2) report that impaired cognition is among the most disabling symptoms and deeply affects their quality of life.
- Trial name
- BraCE-DM2 (NCT05854433)
- Testing
- Non-interventional study
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Mild Cognitive Impairment (MCI), Sarcopenia
Project Gnosis: the Neurophysical and Psychosocial Health Outcomes of Tai Chi for Older Adults with Cognitive Concerns or Mild Cognitive Impairment
Mild Cognitive Impairment (MCI) in older adults is linked to muscle loss (sarcopenia) and can lead to dementia, with pain further impacting cognitive and physical performance.
- Trial name
- NCT06828926
- Testing
- Tai Chi
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ohio University
Patient Fall, Muscle Balance
Home Based Exercise in Preventing Fall and Improving Balance in Older People
Prior studies have shown multifaceted falls prevention program with home-based exercise reduced falls significantly in the community setting.
- Conditions
- Patient Fall, Muscle Balance, Fear of Falling, Quality of Life
- Trial name
- NCT02089815
- Testing
- Home based exercise, fall prevention education and counseling
- Where
- Thailand
- Volunteers
- 439 people
- Sponsor
- Mahidol University
Spinal Cord Injury, Bladder Dysfunction
Quantitative and Qualitative Changes in Neural Efferent Receptors
OBJECTIVE: 1. To study tissues from spinal cord injured patients with noncompliant bladders as well as neurologically intact patients with normal bladder compliance, analyzing both quantitative and qualitative neural efferent…
- Trial name
- NCT00472784
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Musculoskeletal Injury
Effects of Kinesio-Taping and Muscle Energy Technique on Chronic Sacroiliac Joint Dysfunction
Pregnancy is the main occasion of every woman's life in which numerous episodes of physiological and anatomical adjustments takes place within woman's body to become a mother.
- Trial name
- NCT05442476
- Testing
- Kinesiotaping, Muscle Energy Technique, conventional physiotherapy
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Ziauddin University
Sacroiliac Joint Dysfunction
Muscle Energy Techniques and Sacral Manipulation on Pain, Functional Disability and Quality of Life
The study will be randomized clinical trial. This study will be conducted in University of Lahore Teaching Hospital, Lahore, Pakistan.
- Trial name
- NCT05018780
- Testing
- Muscle Energy Technique, Sacral Manipulation
- Where
- Pakistan
- Volunteers
- 76 people
- Sponsor
- University of Lahore
Temporomandibular Joint Disorder
The Effect of Cervical Stabilization Exercises in Temporomandibular Joint
The purpose of this study is; to determine the efficacy of cervical stabilization exercises in the treatment of patients with temporomandibular joint disfunction
- Trial name
- NCT07232303
- Testing
- Cervical stabilization, Home exercises, Patient educating
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Bahçeşehir University
TMD/Orofacial Pain, Muscle Spasm
Dry Needling for Temporomandibular Disorder
This randomized controlled trial investigates the clinical effectiveness of dry needling in individuals with myofascial temporomandibular disorder (TMD).
- Trial name
- DN-TMD (NCT07123883)
- Testing
- Dry Needling
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Atlas University
Heart Failure
The Effects of Sacubitril/Valsartan on Cardiac Oxygen Consumption and Efficiency of Cardiac Work in Heart Failure Patients
This is a phase IV, prospective, randomized, double-blind, double-dummy, parallel-group study. The study assessed the effects of 6 weeks of stable sacubitril/valsartan therapy, as compared with valsartan therapy, on the…
- Trial name
- TurkuPET (NCT03300427)
- Testing
- sacubitril/valsatran, valsartan
- Where
- Finland
- Volunteers
- 55 people
- Sponsor
- Novartis Pharmaceuticals
Temporomandibular Joint Dysfunction; Myofascial Pain Syndrome; Orofacial Pain; Musculoskeletal Disorders
Reflex Therapy of Temporomandibular Dysfunctions
This study aims to evaluate the effectiveness of dry needling in patients with functional temporomandibular pain syndrome by comparing standard rehabilitation therapy alone with therapy combined with dry needling to reduce pain…
- Trial name
- NCT07321483
- Testing
- Dry needling, Standard rehabilitation
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- Palacky University
Physiology
Physiopathology of Lower Cortical Activation in COPD Patients: Contribution of Cortical Neuromodulation
Patients with COPD have lower cortical activation and higher cortical inhibitory levels. The purpose of this study is to test the reversibility the lower cortical activation by counterbalancing the increased cortical inhibitory…
- Trial name
- NCT03368703
- Testing
- Anodal transcranial direct-current-stimulation
- Where
- France
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- 5 Santé
Chronic Pelvic Pain Syndrome
Vaginal Baclofen Suppositories in Chronic Pelvic Pain
The purpose of this study is to evaluate if baclofen vaginal suppositories improve symptoms of Chronic Pelvic Pain (CPP). Participants in this study will take four short questionnaires prior to being randomized.
- Trial name
- NCT05968937
- Testing
- 20 mg baclofen vaginal suppository daily per vagina
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Cricopharyngeal Achalasia
Ultrasound-guided Botulinum Toxin Injection on Cricopharyngeal Muscle Dysfunction
Ultrasound-guided injection is a visual, convenient, and radiation-free technique that allows real-time observation of the needle insertion process and drug injection location.
- Trial name
- NCT06271395
- Testing
- Injectable Type A Botulinum Toxin
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Zeng Changhao
Lower Urinary Tract Dysfunction
Video Game-Based Balance Training in Children With Lower Urinary Tract Dysfunction
This study aims to investigate the effects of video game-based balance exercises, in addition to standard treatment, in children aged 5-12 years with lower urinary tract dysfunction (LUTD).
- Trial name
- NCT07126977
- Testing
- Urotherapy training, Diaphragmatic Breathing Exercise, Biofeedback-Assisted Pelvic Floor Muscle Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Bahçeşehir University
Ventilator-induced Diaphragm Dysfunction, VIDD
Evaluation of heepSync, a Novel Algorithm for Transcutaneous Electrical Stimulation of Respiratory Muscles in Mechanically Ventilated Patients.
Up to 76% of ICU patients on mechanical ventilation develop significant respiratory muscle atrophy within the first 24 hours, contributing to prolonged ventilation, increased morbidity, and higher healthcare costs.
- Conditions
- Ventilator-induced Diaphragm Dysfunction, VIDD, Weaning Failure
- Trial name
- NCT07363902
- Testing
- Heecap
- Where
- 3 sites in Spain
- Volunteers
- 20 people
- Sponsor
- Tesai Care SL
Myofascial Pain Dysfunction Syndrome, Trigger Point Pain, Myofascial
Validity, Reliability of Neck Disability Index in Albanian
To translate and validate the Cervical Disability Index (NDI) into Albanian for use in the Albanian-speaking population
- Trial name
- NDI (NCT06833359)
- Testing
- Observation
- Where
- Spain
- Volunteers
- 582 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Musculoskeletal Pain, TMJ Pain
Association of Jaw Dysfunction With Neck Disability in Subjects With Chronic Cervical Spine Disorders
Since TMJ and cervical pain incidence are rising and both structures are highly interrelated anatomically and functionally. And yet no standard protocol for TMD therapy The objective of this study is to state if there is a…
- Conditions
- Musculoskeletal Pain, TMJ Pain, Cervical Pain
- Trial name
- NCT04849442
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Horus University
Constipation, Constipation - Functional
The Impact of Respiratory Muscle Training and Patient Education on Chronic Constipation Outcomes
The primary aim of this study will be to determine if a respiratory muscle training program that includes both inspiratory muscle training (IMT) and expiratory muscle training (EMT), targeted at improving respiratory muscle…
- Conditions
- Constipation, Constipation - Functional, Dyssynergia
- Trial name
- NCT05823259
- Testing
- Hybrid Telehealth Program: Respiratory Muscle Training and Patient Education, Standard Physical Therapy Care
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Miami