Clinical trials: Muscle Dysfunction
Pelvic Floor Muscle Weakness, Stroke
Multimodal Pelvic Floor Rehabilitation in Chronic Stroke Survivors: Long-Term Efficacy, Optimal Protocols, and Adjunctive Therapies for Comprehensive Pelvic Floor Dysfunction.
Evaluate long-term efficacy of multimodal PFMT in chronic stroke survivors with PFD.
- Trial name
- RCT (NCT07420569)
- Testing
- Core PFMT: 8-12 contractions (6-10s hold), 3 sets/day, progressed over 16 weeks. • Group A (Standard PFMT): 3 supervised/week (weeks 1-8), 1/week (9-16) + home. • Group B (Intensified PFMT): 5/week, Core PFMT: 8-12 contractions (6-10s hold), 3 sets/day, progressed over 16 weeks.
- Where
- Uganda
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Iqra National University
Sepsis
Project 4A: Inspiratory Muscle Training and Diaphragm Strength
Investigators will assess the effect of exercise on markers of inflammation and protein catabolism. This research study will further our understanding of how treating Chronic Critical illness (CCI) - related respiratory muscle…
- Trial name
- NCT02367170
- Testing
- Bilateral phrenic nerve stimulation and measurement of transdiaphragmatic pressure, Midazolam, Volitional Measurement of Maximal Inspiratory Pressure (MIP)
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Florida
Temporomandibular Dysfunction
Bruxism and Severity of Temporomandibular Dsyfunction
The aim of the study was to investigate the effect of bruxism on Temporomanbular joint functionality and dysfunction severity in individuals with Temporomandibular Dysfunction (TMD).
- Trial name
- NCT06053723
- Testing
- Fonseca's Anamnestic Questionnaire, Numeric Pain Scale, Jaw Functionality Limitation Scale-20
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people
- Sponsor
- Bandırma Onyedi Eylül University
Frailty, Aging
Vivifrail Exercise Program in Nonagenarians: Effects on Function, Muscle, and Cognition
This randomized clinical trial investigates the effects of a home-based multicomponent exercise program (Vivifrail) on physical function, muscle morphology, and cognition in community-dwelling adults aged 90 years and older.
- Conditions
- Frailty, Aging, Cognitive Decline
- Trial name
- Vivifrail (NCT07731529)
- Testing
- Vivifrail multicomponent exercise program
- Where
- 2 sites in Brazil
- Volunteers
- 54 people
- Sponsor
- Federal University of Rio Grande do Sul
Chronic Pain, Low Back Pain
Research Protocol for Karuna Labs Inc.: Safety and Efficacy of Virtual Reality Graded Motor Imagery for Chronic Pain
The purpose of this study is to investigate, in two phases: (1) the feasibility and safety of Virtual Embodiment Therapy in treating chronic pain of lower back and upper limbs and (2) the efficacy of Virtual Embodiment Therapy on…
- Conditions
- Chronic Pain, Low Back Pain, Fibromyalgia, Upper Extremity Dysfunction
- Trial name
- NCT04060875
- Testing
- Karuna Labs Virtual Reality Software
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Karuna Labs Inc.
Bruxism, Pelvic Pain
Bruxism, Pelvic Pain, Erectile Dysfunction, and Anxiety in Young Adult Men
Bruxism is a parafunctional activity characterized by clenching or grinding of the teeth during wakefulness or sleep. Increasing evidence suggests that bruxism is not only related to orofacial structures but may also be…
- Conditions
- Bruxism, Pelvic Pain, Myofascial Pain - Dysfunction Syndrome of TMJ, Myofascial Pain Dysfunction Syndrome
- Trial name
- NCT07469345
- Testing
- Questionnaire and Physical Exam
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Temporomandibular Joint Disorders
Treatment of Temporomandibular Dysfunction With Hypertonic Dextrose Injection
Dysfunction of the jaw, associated with pain in the jaw or about the jaw in the face can be quite long lasting and debilitating.
- Trial name
- NCT01706172
- Testing
- Injection of 20% dextrose/ 0.2% lidocaine, Injection of 1 ml of 0.8 Sterile water /0.2% lidocaine
- Where
- Canada
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Chisel Peak Medical Clinic
Temporomandibular Joint Dysfunction
Effect of Intra-articular Injection on Temporomandibular Joint Dysfunction
The goal of this clinical trial is to study about the clinical effect of Intra-articular Injection on Temporomandibular Joint Dysfunction The main question it aims to answer is: Can Intra-articular Injection help improve the…
- Trial name
- NCT06213675
- Testing
- Routine rehabilitation treatment, Intra-articular Injection
- Where
- China
- Sponsor
- Zeng Changhao
Temporomandibular Joint Dysfunction Syndrome
Effectiveness of Cervical Treatment in Wind Musicians With Temporomandibular Dysfunction
Temporomandibular dysfunction (TMD) consists of a series of multifactorial signs and symptoms that occur in the orofacial region, with pain being the most common symptom.
- Trial name
- ANAISATM (NCT05893251)
- Testing
- Manual therapy, Postural exercises
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad de Murcia
Temporomandibular Joint Dysfunction Syndrome
Immediate Effect of Ultrasound Therapy on Bilateral Masseter Myalgia
This study will compare ultrasound 0.4 W/cm^2 and 100% duty cycle versus no ultrasound (placebo) for bilateral masseter myalgia in up to 38 adult women. The dose will be applied for 5 minutes on each side.
- Trial name
- NCT02892994
- Testing
- ultrasound
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- State University of New York at Buffalo
Low Back Pain
Sequential Core Stability Corrective Exercise Approach in Lower Crossed Syndrome
The objective of the study will be to determine the effects of Sequential Core Stability Corrective Exercise Approach for Alignment and Muscle Function in Lower Crossed Syndrome.
- Trial name
- SCSCRLCS (NCT05505851)
- Testing
- Control, Sequential Core Stability Corrective Exercise Approach
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Primary Dysmenorrhea (PD)
Muscle Energy Technique and Myofascial Chain Training for Menstrual Pain in Primary Dysmenorrhea (METPD-25)
This prospective clinical trial evaluates the effects of a non-pharmacological intervention combining muscle energy technique (MET) and myofascial chain (MFC)-based pelvic stabilization training in women with primary dysmenorrhea…
- Trial name
- METPD-25 (NCT07058480)
- Testing
- Combined MET and MFC-Based Pelvic Stabilization Training, Interferential current therapy (ICT), Deep Friction Massage (DFM)
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shanjiao Luo
Temporomandibular Joint Syndrome
Temporomandibular Joint (TMJ) Positioning Accuracy and Efficiency Using a Dental Compass.
This study is being performed to determine if the use of the Dental Compass Articular and its software will produce therapeutic splints for TMD accurately and successfully, compare favorably with a cohort treated without the…
- Trial name
- NCT06619574
- Testing
- 3D Analysis Group, Manual Analysis Cohort
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Dr. Dean Reeves Clinic
Temporomandibular Disorder
Effectiveness of a Home Based Exercise Program on Temporomandibular Dysfunction Syndrome
patients with chronic refractory temporomandibular dysfunction were prescribed home exercise and were followed for 6 months. Pain , mouth opening and Fonseca's were done at day 1 and after 6 months of the study.
- Trial name
- NCT04374682
- Testing
- exercises
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Assiut University
Neck Pain, Central Nervous System Sensitization
Central Sensitization and Clinical Parameters in Chronic Neck Pain
This study is a retrospective, cross-sectional observational study that assesses the correlations among central sensitization, pain, psychosocial factors, and temporomandibular function in patients with chronic neck pain.
- Conditions
- Neck Pain, Central Nervous System Sensitization, Temporomandibular Joint Dysfunction Syndrome, Chronic Pain
- Trial name
- NCT07462416
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Turkoglu Dr. Kemal Beyazit State Hospital
SEPTIC SHOCK, SEPSIS SYNDROME
Early Physical Therapy in Patients With Sepsis
It is clearly shown that patients in the Intensive care Unit (ICU) with severe sepsis or multi organic failure are very susceptible to develop neuromuscular complications.
- Conditions
- SEPTIC SHOCK, SEPSIS SYNDROME, Multiple Organ Dysfunction Syndrome
- Trial name
- EARTH-ICU (NCT01787045)
- Testing
- Early and Active Physical Therapy, Passive Range of Motion
- Where
- Belgium
- Volunteers
- 29 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Posterior Tibial Tendon Dysfunction
Bracing and Strengthening for Posterior Tibial Tendon Dysfunction
Posterior tibial tendon dysfunction (PTTD) is a problem with the tendon connecting one of the lower leg muscles to the foot bone. PTTD can cause pain, swelling, and a flattened foot and may require surgery if left untreated.
- Trial name
- NCT00756457
- Testing
- Bracing, Strengthening exercises, Stretching exercises
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Ithaca College
Temporomandibular Joint Disorders, Facial Pain
Device for Alleviating Temporomandibular Joint (TMJ) Pain
The goal of this clinical trial is to evaluate the safety and effectiveness of the investigational BTL-043 device in alleviating Temporomandibular Joint (TMJ) pain in adults aged 22 years and older.
- Conditions
- Temporomandibular Joint Disorders, Facial Pain, Temporomandibular Joint Dysfunction Syndrome
- Trial name
- NCT07624539
- Testing
- Treatment with BTL-043
- Where
- 3 sites in United States
- Volunteers
- 31 people
- Sponsor
- BTL Industries Ltd.
Massage, Inflammatory Response
Comparison of Different Forms of Recovery on the Functionality After Physical Exercise
Delayed onset muscle soreness (DOMS) and decrease of musculoskeletal function are due to high intensity training and / or sports activities. These occur due to micro lesions of muscle tissue resulting in nociceptor sensitization.
- Conditions
- Massage, Inflammatory Response, Muscle, Skeletal, Cryotherapy Effect
- Trial name
- NCT04201977
- Testing
- Foam Roller Recovery, Active recovery, Immersion in cold water
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Santa Maria
Muscle Atrophy or Weakness, Ventilator-associated Lung Injury
Serial Daily Diaphragm Ultrasounds in Ventilated Patients
When a person is put on a breathing machine the investigators think that the breathing muscles can get weaker. The investigators are not sure how quickly this happens but in some people this leads to problems when they try to…
- Trial name
- NCT02174029
- Testing
- Ventilation- mandatory, Ventilation- voluntary mode only, Voluntary with preceding mandatory
- Where
- Canada
- Volunteers
- 61 people
- Sponsor
- Steve Reynolds