Clinical trials: Muscle Dysfunction
Pain, Chronic, Obstructive Pulmonary Disease
Comparison of Respiratory Muscle, Pain, Functional Performance and Cognitive Status in Obstructive Lung Diseases
In the literature, there are a limited number of studies evaluating postural awareness, cognitive status, respiratory muscle strength and endurance, functional capacity, and pain in people with obstructive pulmonary disease, and…
- Conditions
- Pain, Chronic, Obstructive Pulmonary Disease, Cognitive Impairment, Functional Disturbance
- Trial name
- NCT04048408
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Ageing, Frailty
Physiotherapy Interventions on Functional Capacity, Balance and Mental Domains in Community-Dwelling Older Adults: A Randomized Clinical Trial With Two Parallel Groups
This study will investigate whether two different physiotherapy exercise programs can improve physical function, balance and mental well-being in older adults living in the community in Angola.
- Conditions
- Ageing, Frailty, Sarcopenia, Decline, Cognitive
- Trial name
- NCT07424274
- Testing
- Multicomponent Physiotherapy Exercise Program, Reduced Functional Physiotherapy Exercise Program
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Aveiro University
Type2 Diabetes, Obesity
PGC-1 & MUSCLE MITOCHONDRIAL DYSFUNCTION IN DIABETES: AIMS 1-4
We are trying to understand how insulin (a type of hormone in the body that regulates how the body regulates how one metabolizes protein and carbohydrates) and exercise alter proteins involved in energy production and metabolism…
- Trial name
- NCT03323788
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- University of Arizona
Levator Ani Syndrome
A Study Examining the Use of Vaginal Nifedipine With Pelvic Floor Physical Therapy for Levator Myalgia and Pelvic Pain
The objective of this study is to perform a randomized controlled trial among female patients with a diagnosis of pelvic floor hypertonus (extreme muscle tension) with associated pain, dysfunctional voiding, dyspareunia, and/ or…
- Trial name
- NCT01586286
- Testing
- Nifedipine
- Where
- United States
- Sponsor
- Vanderbilt University
Temporomandibular Joint Dysfunction, Pain
Efficacy of Arthrocentesis by Injection of Ringer With or Without Corticosteroid in Treatment of Internal Derangement
The study aims to evaluate effectiveness of ringer injection with or without corticosteroid during arthrocentesis of the temporomandibular joint in the treatment of internal derangement of the temporomandibular joint (TMJ).
- Conditions
- Temporomandibular Joint Dysfunction, Pain, Arthrocentesis
- Trial name
- NCT01958879
- Testing
- ringer with corticosteroid, ringer without corticosteroid
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Shiraz University of Medical Sciences
Temporomandibular Disorder, Temporomandibular Joint Dysfunction
Trauma Exposure and Childhood Trauma in Temporomandibular Joint Disorders
Temporomandibular disorder is a multifactorial condition that involves the temporomandibular joint, masticatory muscles, and surrounding structures and is influenced by biological, psychological, and social factors.
- Conditions
- Temporomandibular Disorder, Temporomandibular Joint Dysfunction, Trauma Exposure, Childhood Traumas
- Trial name
- NCT07292103
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Gulseren Demir Karakilic
Cardiac Implantable Electronic Device (CIED), Shoulder Dysfunction
Long-term Effects of Early Shoulder Exercise After CIED Implantation
Shoulder dysfunction frequently occurs after cardiac implantable electronic device (CIED) implantation, adversely affecting quality of life.
- Trial name
- NCT07496554
- Testing
- Structured Stretching and Strengthening Program, Standard Post-operative Care, Pendulum Exercise Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 89 people
- Sponsor
- Erzincan Binali Yildirim Universitesi
Musculoskeletal Pain, Musculoskeletal Strain
Surgeon Ergonomics in Robotic-assisted Laparoscopic Vs Standard Laparoscopic Surgery
Musculoskeletal injuries amongst surgeons are prevalent. This project will determine whether Robotic-assisted Laparoscopic surgery (RALS) offers superior benefits to surgeon's musculoskeletal health than standard laparoscopic…
- Conditions
- Musculoskeletal Pain, Musculoskeletal Strain, Fatigue; Muscle, Heart, Cognitive Impairment
- Trial name
- MURALS (NCT04477746)
- Where
- 2 sites in United Kingdom
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Lancaster University
Amyotrophic Lateral Sclerosis (ALS), Myasthenia Gravis
Innovative Measures of Speech and Swallowing Dysfunction in Neurological Disorders
This study is evaluating the use of two painless, non-invasive technologies in the assessment of muscle health over time in both healthy volunteers and patients who have diseases that affect the nervous system.
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Myasthenia Gravis, Myopathies, Stroke
- Trial name
- QUESST (NCT02118805)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Spasticity as Sequela of Stroke, Spastic Hemiplegia
Modulation of Upper Limb Spasticity Post-Stroke
Stroke is one of the commonest causes of severe disability in adults. Stroke often results in spasticity and motor impairments in the upper limb.
- Conditions
- Spasticity as Sequela of Stroke, Spastic Hemiplegia, Upper Extremity Dysfunction
- Trial name
- NCT05069480
- Testing
- Virtual reality-based training equipment., Traditional physical therapy program
- Where
- Saudi Arabia
- Volunteers
- 38 people
- Sponsor
- Umm Al-Qura University
Frailty Syndrome, Cognitive Impairment
Successful Aging and Frailty
Frailty is the term commonly utilized to describe the geriatric syndrome that exposes the elderly to increased risk of negative health-related events.
- Conditions
- Frailty Syndrome, Cognitive Impairment, Sarcopenia
- Trial name
- SAFe (NCT03963050)
- Testing
- Exercise Training, Exercise Training + Cognitive Training, Control
- Where
- Italy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Facial Pain, Temporomandibular Disorder
Physical Exercises for Temporomandibular Disorders
Temporomandibular Disorders are a common clinical picture that appear in particular in people between the age of 20 and 40 years. About 33% of the total population shows symptoms and signs of TMD.
- Conditions
- Facial Pain, Temporomandibular Disorder, Temporomandibular Joint Disorders, Temporomandibular; Functional Disturbance
- Trial name
- NCT04819763
- Testing
- Physical therapy, Appliance therapy
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University Medicine Greifswald
Acute Kidney Injury, Rhabdomyolysis
Myoglobin Removal With CytoSorb in Rhabdomyolysis
The aim of this observational study is to assess whether myoglobin removal with CytoSorb® ameliorates endothelial damage in severe rhabdomyolysis patients who are admitted to the intensive care unit.
- Conditions
- Acute Kidney Injury, Rhabdomyolysis, Endothelial Dysfunction
- Trial name
- NCT06503289
- Testing
- Cytosorb therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 17 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Urinary Incontinence, Urinary Incontinence, Stress
Pelvic Floor Rehabilitation Programme for Women With Urinary Incontinence in a Peruvian Public Hospital
This study evaluates whether a 12-week pelvic floor rehabilitation programme improves urinary incontinence symptoms in adult women treated at Hospital Nacional Edgardo Rebagliati Martins, a public tertiary hospital in Lima, Peru.
- Conditions
- Urinary Incontinence, Urinary Incontinence, Stress, Urinary Incontinence, Urge, Mixed Urinary Incontinence
- Trial name
- NCT07858968
- Testing
- Supervised group pelvic floor muscle training, Individual physiatrist-led pelvic floor sessions
- Where
- Peru
- Volunteers
- 89 people
- Sponsor
- Hospital Nacional Edgardo Rebagliati Martins
Pelvic Floor Disorders, Lower Urinary Tract Symptoms
Respiratory and Pelvic Floor Muscle Functions of Children With Lower Urinary Tract Dysfunction
Lower urinary tract dysfunctions (LUTD) are disorders that can occur in the storage and voiding stages of bladder function other than neurological disease or lower urinary tract obstruction.
- Conditions
- Pelvic Floor Disorders, Lower Urinary Tract Symptoms, Physical Activity
- Trial name
- NCT06728540
- Testing
- Investigation of Physical Activity Levels, Respiratory and Pelvic Floor Muscle Function
- Where
- Turkey (Türkiye)
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Seda Yakit Yesilyurt
Hepatitis C, Chronic, Cognition Disorders
Study of Cerebral Function in Patients With Chronic Hepatitis C Infection (HCV/CNS)
Patients with HCV infection often suffer from chronic fatigue, depression and reduced cognition, even before evolving severe liver fibrosis, liver cirrhosis and hepatic encephalopathy.
- Conditions
- Hepatitis C, Chronic, Cognition Disorders, Fatigue Syndrome, Chronic, Major Depressive Disorder
- Trial name
- NCT00788918
- Testing
- Interferon and ribavirin
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Fibromyalgia, Cognitive Dysfunction
Relationship Between Central Sensitization Symptoms and Cognitive Dysfunction in Fibromyalgia
The aim of the study is to investigate the relationship between central sensitization parameters and cognitive dysfunction in patients with fibromyalgia.The main questions it aims to answer are: Do central sensitization symptoms…
- Conditions
- Fibromyalgia, Cognitive Dysfunction, Central Sensitisation
- Trial name
- NCT06948903
- Testing
- Central Sensitization Inventory, The Montreal Cognitive Assessment, Cognitive Symptom Severity Scale-Extended
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Temporomandibular Joint Dysfunction Syndrome
Analysis of Clinical Data of Patients With Temporomandibular Joint Disorder
According to our previous research and clinical observation results, the motor function of the oral, maxillofacial and cervical body is closely related to the occlusal contact.
- Trial name
- NCT05780827
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Air Force Military Medical University, China
Temporal Mandibular Joint Dysfunction
Effect of Rocabado Exercises With Strain Counter-Strain Technique on Muscles of Mastication for Pain, Jaw Function, and Quality of Life in Patients With Temporomandibular Joint Dysfunction
Temporomandibular joint dysfunction (TMD) is a common musculoskeletal disorder affecting the jaw joint and masticatory muscles, leading to pain, limited jaw function, and reduced quality of life.
- Trial name
- NCT07703059
- Testing
- Rocabado Exercise, Strain Counterstrain Technique
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Interstitial Lung Disease, Idiopathic Pulmonary Fibrosis
Skeletal Muscle Function in Interstitial Lung Disease
Dyspnea (i.e. breathlessness) and exercise intolerance are common symptoms for patients with interstitial lung disease (ILD), yet it is not known why.
- Conditions
- Interstitial Lung Disease, Idiopathic Pulmonary Fibrosis, Hypersensitivity Pneumonitis, Scleroderma
- Trial name
- NCT03800017
- Testing
- Hyperoxia
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of British Columbia