Clinical trials: Muscle Fiber Type
Neuromuscular Disease, Malignant Hyperthermia
The Prevalence of RYR1-related Disease
The skeletal muscle ryanodine receptor (RYR1) gene encodes an important calcium channel in skeletal muscle, with an important role in muscle contraction. Mutations (i.e.
- Conditions
- Neuromuscular Disease, Malignant Hyperthermia, Congenital Myopathy, Multiminicore Disease
- Trial name
- NCT06791369
- Where
- United Kingdom
- Volunteers
- 2,000 people
- Sponsor
- King's College London
Elite Cyclists
Predicting the Efficacy of Resistance Exercise Training for Improving Endurance Performance
The overall objective of the study is to identify molecular determinants of the efficacy of resistance training for improving endruance performance in elite cyclists
- Trial name
- IDperform (NCT04637178)
- Testing
- Resistance training, Endurance training (habitual)
- Where
- Norway
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Inland Norway University of Applied Sciences
Type 2 Diabetes
Exercise Resistance in Type 2 Diabetes
The purpose of this study is to collect data to help researchers identify factors that prevent certain individuals from receiving the beneficial effects of exercise.
- Trial name
- RESIST (NCT01911104)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Central Core Disease, Centronuclear Myopathy
Molecular and Genetic Studies of Congenital Myopathies
In the Congenital Myopathy Research Program at Boston Children's Hospital and Harvard Medical School, the researchers are studying the congenital myopathies (neuromuscular diseases present from birth), including central core…
- Conditions
- Central Core Disease, Centronuclear Myopathy, Congenital Fiber Type Disproportion, Multiminicore Disease
- Trial name
- NCT00272883
- Where
- United States
- Volunteers
- 4,000 people
- Sponsor
- Boston Children's Hospital
Muscle Fiber Type, Exercise
Muscle Typology and Strength Training Adaptations
The overall aim of this project is to investigate if the responsiveness to chronic resistance training is dependent on the muscle typology.
- Conditions
- Muscle Fiber Type, Exercise, Training Frequency
- Trial name
- MT-ST (NCT05108181)
- Testing
- Muscle typology + exercise training, Muscle typology + training frequency
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Ghent
Insulin Resistance, Insulin Resistance and Type 2 Diabetes
The Muscle Monitor: Early Skeletal Muscle Indicators of Insulin Resistance and Cardiometabolic Risk
Insulin resistance is an early etiological factor in the development of type-2 diabetes (T2D), which constitutes a large societal health burden with an expected additional rise in the years to come.
- Conditions
- Insulin Resistance, Insulin Resistance and Type 2 Diabetes, Cardiometabolic Risk Factors, Physical Activity
- Trial name
- MUSCLE MONITOR (NCT07678736)
- Where
- Belgium
- Volunteers
- 250 people
- Sponsor
- University Ghent
Low Back Pain, Back Pain Lower Back Chronic
The Forgotten Role of Back Muscle Characteristics to Tailor Exercise Therapy for Recurrent Non-specific Low Back Pain
Patients with non-specific low back pain will be compared to healthy, age- and sex-matched controls to determine the most discriminating back muscle characteristics and to delineate possible phenotypes of patients with…
- Trial name
- Back-to-Back (NCT05851196)
- Testing
- Proprioceptive training
- Where
- 2 sites in Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Muscle Fiber Atrophy, Type II
The Effect of Neuromuscular Electrical Stimulation (NMES)
The purpose of this project is to test the effectiveness of neuromuscular electrical stimulation (NMES) that produces 40 % of maximum voluntary contraction (MVC) in increasing muscle size and improvement in muscle force output…
- Trial name
- NMES (NCT00765739)
- Testing
- Neuromuscular electrical stimulation, voluntary strengthening exercise
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Cerebral Palsy (CP)
Spastic Myopathy in Adults With Cerebral Palsy
Cerebral palsy (CP) is indeed the result of a central neurological lesion, but it also involves a lesser-known muscular condition that we refer to as spastic myopathy.
- Trial name
- MYOSPAS-IMC (NCT07293988)
- Testing
- Guided Self-rehabilitation Contract, Conventional therapy group
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Neuroloco