Clinical trials: Muscle Hypertrophy
Proteomics, Exercise
Dynamic Proteomics and Integrated Rates of Muscle Protein Synthesis During an Acute Period of Loading and Unloading
Skeletal muscle plays several different roles in the promotion and maintenance of health and well-being. The loss of muscle mass that occurs with aging, chronic muscle wasting diseases, and physical inactivity puts people at an…
- Conditions
- Proteomics, Exercise, Atrophy, Disuse, Hypertrophy
- Trial name
- HYPAT (NCT04514744)
- Testing
- Knee bracing, Unilateral Resistance Exercise Training
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- McMaster University
Muscle Hypertrophy in Healthy Young Men
Effects of Deloading Periods in Resistance Training on Muscular Strength and Hypertrophy
This study investigates the effects of deloading periods (short breaks or reductions in training volume) in a 8-week resistance training program on muscle strength and hypertrophy in young, untrained individuals.
- Trial name
- DPRT (NCT06825052)
- Testing
- Resistance Training with Deloading Periods, Continuous Resistance Training
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Gaziantep
Aging, Muscular Atrophy
Maximizing Mechanisms of Muscle Hypertrophy to Combat Sarcopenia in Older Adults
Resistance training has shown the most promise among interventions aimed to combat aging muscle atrophy as it enhances strength, power, and mobility function, but induces varying degrees of skeletal muscle hypertrophy as the…
- Trial name
- NCT02442479
- Testing
- resistance training
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Healthy
Plant-based Dietary Protein and Resistance-training Adaptations
Dietary protein consumption maximizes the anabolic response during resistance training (RT) by triggering muscle protein synthesis and providing the indispensable amino acids for a net positive protein balance.
- Trial name
- NCT03907059
- Testing
- whey protein, soy protein
- Where
- Brazil
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Sarcopenia, Cardiovascular Disease
Egg Cholesterol Consumption, Blood Cholesterol and Skeletal Muscle Hypertrophy
The purpose of this study is to examine the effect of dietary cholesterol administered as whole egg or egg white (control)on muscle mass gain with resistance training in a young old population of men and women (age 50-69).
- Trial name
- NCT00260442
- Testing
- Resistance Training, Sedentary
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Muscle Hypertrophy, Muscular Strength
Determining the Effect of Shoulder Flexion Angle on Latissimus Dorsi and Forearm Flexor Hypertrophy
The goal of this clinical trial is to learn the effect of training a muscle at a longer or shorter muscle length during resistance exercise in young and healthy adults.
- Trial name
- LPDLR (NCT07360236)
- Testing
- LAT PULLDOWN and LAT ROW training sessions, Maximal isotonic strength testing (1RM), Isokinetic strength testing (1080 Quantum)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Muscle Atrophy, Disuse Atrophy (Muscle) of Lower Leg
The Regulation of Human Skeletal Muscle Mass by Contractile Perturbation
It is well known that periods of weight training lead to increases in skeletal muscle size and strength. In contrast, periods of inactivity such as bed rest or immobilization result in losses of skeletal muscle size and strength.
- Trial name
- HYPAT (NCT03046095)
- Testing
- Unilateral Resistance Exercise, Immobilization
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- McMaster University
Obesity, Overfeeding
Overeating Different Fats and Influence on Muscle Mass and Body Fat Accumulation
To investigate metabolic and molecular response to fatty acid-specific overfeeding in overweight subjects, in relation to changes in ectopic fat, lean tissue mass and insulin sensitivity
- Conditions
- Obesity, Overfeeding, Muscle Mass, Body Composition
- Trial name
- LIPOGAIN-2 (NCT02211612)
- Testing
- PUFA-group, SFA-group
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Exercise, Nutrition Therapy
Effects of Whey Protein and Collagen Supplementation
The present project aims to investigate the effects of high-quality protein (whey protein) vs. low-quality protein (collagen) on muscle mass and function (e.g., strength and power) during a 10-wk resistance training program in…
- Conditions
- Exercise, Nutrition Therapy, Resistance Training, Muscle Strength
- Trial name
- NCT04213586
- Testing
- Whey protein supplementation, Collagen supplementation
- Where
- Brazil
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Universidade Norte do Paraná
Coronary Disease, Healthy
Study of Blood Flow in Heart Muscle
Blood flows to areas of the heart providing oxygen and fuel to the pumping muscle. Occasionally the arteries providing the fuel can become blocked. This occurs in coronary artery disease.
- Conditions
- Coronary Disease, Healthy, Hypertrophic Cardiomyopathy, Myocardial Ischemia
- Trial name
- NCT00001631
- Testing
- Magnetic resonance imaging
- Where
- United States
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Hypertrophy, Muscle Strength
Reliability and Performance Analysis of the Use of Tissue Flossing for Blood Flow Restriction.
Blood flow restriction (RFS) is a widely studied technique that combines low-intensity exercise with vascular occlusion, resulting in muscular benefits.
- Trial name
- NCT06075901
- Testing
- Tissue Flossing, Blood Flow Restriction Cuff, Training Protocol
- Where
- Brazil
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Paulista University
Hypertrophy, Muscle Strength
Applicability of Tissue Flossing for Blood Flow Restriction in the Upper Limb: Reliability and Performance Analysis
Blood flow restriction (BFR) is a widely studied technique that combines low-intensity exercise with vascular occlusion, resulting in muscular benefits.
- Trial name
- NCT06512961
- Testing
- Tissue Flossing, Blood Flow Restriction Cuff, Training Protocol
- Where
- Brazil
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Paulista University
Sarcopenia, Muscular Atrophy
Exercise and Nutrition Interventions in Age-related Sarcopenia
This project will investigate the synergistic effects of Aerobic and Resistance type Exercise, in combination with Protein Supplementation, on; Body Composition, Musculoskeletal Functioning, Nutritional Status and Quality of Life…
- Trial name
- NCT02912130
- Testing
- Protein Supplementation, Aerobic Exercise, Resistance Exercise
- Where
- United Kingdom
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Liverpool Hope University
Resistance Training, Muscle Hypertrophy
High- and Low-Load Resistance Training
The goal of this clinical trial is to learn whether low-load resistance training performed to muscle failure can produce similar increases in muscle size and strength as high-load resistance training in healthy untrained young…
- Trial name
- NCT07412600
- Testing
- Low-load resistance training (30% 1RM), High-load resistance training (75% 1RM)
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Hypertrophy
Egg Consumption and Muscular Adaptations
Eggs may be a viable alternative to various types of supplemental proteins given its similar ratings on various measures of dietary protein quality.
- Trial name
- NCT04381390
- Testing
- Whole egg and resistance training, Egg whites and resistance training
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alexei Wong
Core Muscle Weakness, Postural Control Deficit
"CORE Training for Musculoskeletal Health: A Study on Adaptive Exercise Protocols"
This study aims to evaluate the effects of an adaptive core training protocol that integrates core stability, core strength, and high-intensity core power exercises on muscle activation, hypertrophy, balance, and quality of life.
- Conditions
- Core Muscle Weakness, Postural Control Deficit, Trunk Stability Impairment, Functional Performance Limitation
- Trial name
- RCT-EMG-US-QoL (NCT07025395)
- Testing
- - Core Training Protocol, Control Group Core Routine
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ioannis Tsartsapakis
Menopause Related Conditions, Exercise Training
Effects of Estrogen on Muscle Gain During 12-weeks of Exercise in Post-menopausal Women
As females age and transition through menopause, the decline in oestrogen level profoundly affects skeletal muscle mass and function.
- Trial name
- HER-MUSCLE (NCT07617454)
- Testing
- Estrogel, Physical exercise
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mette Hansen
Muscular Hypertrophy
Resistance Training and Milk Supplementation
Post-resistance training high protein milk supplementation may be a viable method to elicit muscular gains. The investigators hypothesis is that high protein milk supplementation would improve skeletal regulatory markers…
- Trial name
- NCT04509297
- Testing
- high protein milk
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Marymount University
Healthy Adult, Athlete
Comparison Between Eccentric Hamstring Training and Sprint-Specific Training
The purpose of this study is to compare the effects of an intensity-, volume-, and time under tension-matched eccentric hamstring exercise intervention with the Romanian deadlift (RDL) and the Nordic hamstring exercise (NHE) to a…
- Conditions
- Healthy Adult, Athlete, Exercise Training, Sport
- Trial name
- NCT07716319
- Testing
- RDL, NHE, Sprint testing
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Hypertrophy, Body Weight Changes
Examining Changes in Muscle Size and Body Composition Between Two Hypertrophy Resistance Training Programs in Males
This study aims to investigate if a less physically and psychologically taxing approach to resistance training can generate equal or greater outcomes when compared to a more physically and psychologically taxing approach.
- Conditions
- Hypertrophy, Body Weight Changes, Muscle Size
- Trial name
- NCT05667233
- Testing
- Resistance Training Program
- Where
- Canada
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Dalhousie University