Clinical trials: Muscle Mass and Strength
Sarcopenia
Integrated Physical Training With Protein Diet in Older Adults With Sarcopenia Symptoms.
Sarcopenia is the major health concern and common consequence of COVID-19 in the aging population. Moreover, this clinical condition has not been considered in usual physical rehabilitation practice, and its optimal protein…
- Trial name
- NCT05224453
- Testing
- Physical training and high protein diet, Physical training and low protein diet
- Where
- Saudi Arabia
- Volunteers
- 76 people
- Sponsor
- Prince Sattam Bin Abdulaziz University
Muscle Composition, Obesity
The Effects of Strength Training on Muscle Mass and Mental Health in Adults Taking Obesity Medication
The purpose of this study is to examine the effects of resistance exercise, such as weightlifting, on retention of muscle mass and mental health in individuals taking GLP-1 RAs (an obesity medication).
- Conditions
- Muscle Composition, Obesity, Quality of Life (QOL)
- Trial name
- STRONG (NCT07652333)
- Testing
- Resistance Exercise, GLP-1 RAs
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Pittsburgh
Skeletal Disorder
Bone and Muscle Health in Kids
Vitamin D deficiency in childhood leads to poor bone growth and muscle weakness, yet it is unknown if the amount of vitamin D a woman consumes during her pregnancy affects her child's bone and muscle development.
- Trial name
- BONUSKids (NCT03537443)
- Testing
- Cholecalciferol (vitamin D3)
- Where
- Bangladesh
- Volunteers
- 642 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Head and Neck Neoplasms
Exercise After Radiation for Head & Neck Cancer
People who receive radiation therapy for head and neck cancer (HNC) can experience side-effects which include a significant loss in body mass and a loss of muscle mass (cancer cachexia).
- Trial name
- NCT04013178
- Testing
- Accentuated eccentric loading + electromyostimulation, Conventional resistance training
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- University of Calgary
Heart Failure
High-Protein Diet and HMB Supplementation in Patients With Heart Failure
The goal of this clinical trial is to evaluate the effects of a high-protein diet with or without HMB supplementation compared with a normoprotein diet on clinical, nutritional, and functional outcomes in patients with heart…
- Trial name
- NCT07731048
- Testing
- β-Hydroxy-β-Methylbutyrate (HMB), Individualized Dietary Counseling
- Where
- Brazil
- Volunteers
- 84 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Sarcopenic Obesity
Effectiveness of a Care Model for Sarcopenic Obesity in Older Adults on Fat Mass, Muscle Mass, Muscle Strength, and Physical Performance
Older adults
- Trial name
- NCT07523672
- Testing
- sarcopenic obesity modification programe
- Where
- Thailand
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Srinakharinwirot University
Breast Cancer Survivors, Postmenopause
Resistance-type Exercise Training in Postmenopausal Women Survivors of Breast Cancer
Background: In postmenopausal women, an alteration in body composition occurs as a consequence of the secretion of low levels of serum estrogens by the ovaries.
- Conditions
- Breast Cancer Survivors, Postmenopause, Resistance Training
- Trial name
- MUSCLE-CLIM (NCT05690295)
- Testing
- Prolonged resistance-type exercise training
- Where
- Chile
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Universidad de La Frontera
Hypertrophy
Neuromuscular Characteristics of Strict Vegetarians and Non-Vegetarians Women
A strict vegetarian diet includes only foods of plant-based origin and, despite being able to meet the nutritional needs of individuals of different ages, when correctly planned, it commonly offers a lower protein intake than a…
- Trial name
- NCT05576337
- Testing
- 16 weeks of strength training protocol
- Where
- Brazil
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Blood Flow Restriction Exercise, Resistance Training
Low Load With Blood Flow Restriction for Improving Strength, Balance, and Cognition in Older Adults
This study aims to examine the effects of low load resistance exercise with a blood flow restriction cuff on muscle strength, balance, physical performance, depression, and cognitive function in community-dwelling older adults.
- Conditions
- Blood Flow Restriction Exercise, Resistance Training, Elderly (People Aged 65 or More), Muscle Strength
- Trial name
- BFRT (NCT06962514)
- Testing
- Blood flow restriction cuff, Exercise without BFR cuff
- Where
- South Korea
- Volunteers
- 26 people
- Sponsor
- Sahmyook University
Type 2 Diabetes Mellitus
Muscle Strength Training for Older Adults With Type II Diabetes
This randomised controlled trial aims to investigate a resistance training program for improving glycemic control, muscle mass, strength and functional performance in older patients with Type II Diabetes (T2 DM).
- Trial name
- NCT03280758
- Testing
- Muscle Strengthening exercises
- Volunteers
- 60 people
- Sponsor
- The University of Hong Kong
Sarcopenia
Magnesium Supplementation as a Nutritional Intervention in Sarcopenia
Sarcopenia is a progressive condition common in older adults and is characterized by loss of muscle strength, muscle mass, and physical performance.
- Trial name
- SARCOMAG (NCT07567963)
- Testing
- Citrate Magnesium Supplementation
- Where
- Portugal
- Volunteers
- 352 people, healthy volunteers welcome
- Sponsor
- Escola Superior de Saúde - Universidade do Algarve
Spinal Cord Injury, Spinal Cord Injuries
Testosterone Plus Finasteride Treatment After Spinal Cord Injury
The purpose of this study is to determine whether testosterone plus finasteride treatment will improve musculoskeletal health, neuromuscular function, body composition, and metabolic health in hypogonadal men who have experienced…
- Conditions
- Spinal Cord Injury, Spinal Cord Injuries, Trauma, Nervous System, Wounds and Injuries
- Trial name
- NCT02248701
- Testing
- Testosterone Enanthate, Finasteride
- Where
- 2 sites in United States
- Volunteers
- 33 people
- Sponsor
- VA Office of Research and Development
Sarcopenia in Elderly, Sarcopenia
Effect of the Consumption of Cookies Enriched With Plant Proteins and of a Vitamin D Supplement on the Progression of Sarcopenia in the Elderly
The ageing population makes it necessary to find effective strategies for the prevention of sarcopenia (the progressive loss of muscle mass and strength and a decline in physical performance) that can be counteracted with foods…
- Conditions
- Sarcopenia in Elderly, Sarcopenia, Nutritional Intervention, Microbiome Analysis
- Trial name
- SARC-PEA (NCT07356440)
- Testing
- Vitamin D3 supplement, Protein-enriched biscuits, Control biscuit
- Where
- 3 sites in Italy
- Volunteers
- 74 people
- Sponsor
- University of Udine
Liver Cirrhosis
Treatment of Sarcopenia Improves the Muscle Mass and Muscle Strength of Patients With Liver Cirrhosis-Child C
Sarcopenia is defined as loss of skeletal muscle mass. In cirrhosis, due to impaired urea genesis and decreased hepatic ammonia disposal, the skeletal muscle functions as a metabolic partner for the liver.
- Trial name
- NCT03633279
- Testing
- Branched chain amino acid
- Where
- India
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Dayanand Medical College and Hospital
Prostate Cancer
Use of β-hydroxy-β-methylbutyrate to Counteract Muscle Loss in Men With Prostate Cancer on Androgen Ablation
This is a study of HMB plus amino acids in older men with prostate cancer starting androgen deprivation therapy (ADT). The investigators hypothesize that the use of this nutritional supplementation will decrease the loss of…
- Trial name
- NCT01607879
- Testing
- Standard of care ADT + (HMB + arginine + glutamine), Standard of care ADT
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Medical College of Wisconsin
Sarcopenia, Grip Strength
Multicomponent Intervention in Women at Risk of Sarcopenia
The goal of this quasi-experimental pilot study is to evaluate the effect of a multi-component intervention in women between 55 and 75 years old at risk of sarcopenia.
- Conditions
- Sarcopenia, Grip Strength, Gait Speed, Body Composition
- Trial name
- NCT06038500
- Testing
- Multicomponent intervention of resistance exercises, dancing sessions and nutritional education
- Where
- Mexico
- Volunteers
- 14 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Lean Body Mass, Chronic Kidney Diseases
Novel Equations for Estimating Lean Body Mass in Patients With Chronic Kidney Disease
Simplified methods to estimate lean body mass (LBM), an important nutritional measure representing muscle mass and somatic protein, are lacking in non-dialyzed patients with chronic kidney disease (CKD).
- Trial name
- NCT04074278
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking University First Hospital
Secondary Osteoporosis, Sarcopenia
The Effect of Exoskeletal-assisted Walking Combined With Transcutaneous Spinal Cord Stimulation on Bone Strength.
Immobilization following spinal cord injury (SCI) results in muscle and bone loss below the level of injury, which ultimately predisposes to fracture at several sites throughout the legs and can lead to several medical…
- Trial name
- NCT07325149
- Testing
- Exoskeleton-Assisted Walking (EAW) + active Transcutaneous Spinal Cord Stimulation (tSCS)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Bronx VA Medical Center
SARS-CoV 2
Muscle Mass and Strength as Predictors of Time to Discharge in Patients With COVID-19
The severe acute respiratory syndrome induced by the new coronavirus (SARS-CoV-2) has been declared a worldwide pandemic. Identifying common characteristics of the disease is crucial to promote a better prognosis for patients and…
- Trial name
- NCT04406233
- Where
- Brazil
- Volunteers
- 176 people
- Sponsor
- University of Sao Paulo
Oxidative Stress, Muscle Strength
The Short Term Effects of Oceanix Supplementation on Recovery
The purpose of this study will be to examine the effects of Oceanix supplementation on isometric mid-thigh pull force kinetics and salivary immunoglobulin A (indice of immune function) following a one-week intense resistance…
- Conditions
- Oxidative Stress, Muscle Strength, Resistance Training, Muscle Damage
- Trial name
- NCT04315077
- Testing
- Oceanix®, Resistance Training
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Applied Science & Performance Institute