Clinical trials: Muscle Performance
Health Behavior
SWAP-MEAT With Athletes for MC-URC: Three Diets on Athletic Performance
This study aims to investigate the impact of two plant-based diets-whole food plant-based (WFPB) and plant-based meat alternatives (PBMA)-vs. an omnivorous diet (Animal) on endurance and muscular strength in recreational athletes.
- Trial name
- NCT06014307
- Testing
- Diet order: PBMA, Animal, Diet order: Animal, PBMA
- Where
- 5 sites in United States, United Kingdom
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Stanford University
Strength, Body Composition
Omega-3 Fatty Acid Supplementation to Enhance Performance
The goal of this intervention study is to determine if omega-3 fatty acid supplementation as compared to placebo improves performance in track and field athletes. The main questions it aims to answer are: 1.
- Conditions
- Strength, Body Composition, Muscle Soreness
- Trial name
- FO n-3 (NCT05924139)
- Testing
- Omega-3 fatty acid
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Baylor University
Spinal Muscular Atrophy, Spine Deformity
Study of an Intrathecal Port and Catheter System for Subjects With Spinal Muscular Atrophy
The primary objective of the clinical investigation is to demonstrate successful clinical use of the ThecaFlex DRx™ System in delivering nusinersen in subjects with spinal muscular atrophy (SMA).
- Conditions
- Spinal Muscular Atrophy, Spine Deformity, Scoliosis
- Trial name
- PIERRE (NCT05866419)
- Testing
- ThecaFlex DRx System
- Where
- 21 sites in United States, Germany and 3 more
- Volunteers
- 90 people
- Sponsor
- Alcyone Therapeutics, Inc
Stroke, Inspiratory Muscle Training
Effects of Inspiratory Muscle Training on the Functional Gait Performance of Individuals After Stroke
The most commonly observed sequel after stroke is muscle weakness, which can also be identified in respiratory muscles, in the acute and chronic phases, and may compromise the lung function of these individuals.
- Conditions
- Stroke, Inspiratory Muscle Training, Quality of Life, Gait
- Trial name
- NCT03171272
- Testing
- Inspiratory Muscle Training
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Lorena de Oliveira Vaz Miranda
Chronic Obstructive Pulmonary Disease (COPD), Asthma
Predicting Dynamic Inspiratory Muscle Strength in COPD and Asthma Patients
This observational study evaluates whether dynamic inspiratory muscle strength can be estimated in patients with chronic obstructive pulmonary disease (COPD) and asthma using simple clinical and performance-based measurements.
- Trial name
- DIMS-PRED (NCT07598292)
- Where
- Turkey (Türkiye)
- Volunteers
- 123 people
- Sponsor
- Hitit University
Myasthenia Gravis
Benefits and Tolerance of Exercise in Patients With Generalized and Stabilized Myasthenia Gravis
The purpose of this study is to demonstrate that a 3 months physical exercise programme improves the Quality of Life of patients with generalized Myasthenia Gravis (MG) stabilized since at least 6 months under prednisone and/or…
- Trial name
- MGEX (NCT02066519)
- Testing
- Physical exercise programme using a rowing machine
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Duchenne Muscular Dystrophy, Performance
Regression of Hamstring Flexibility and Performance in Children With Duchenne Muscular Dystrophy
Investigator investigated that regression of hamstring flexibility and performance in children with Duchenne Muscular Dystrophy.
- Conditions
- Duchenne Muscular Dystrophy, Performance, Flexibility
- Trial name
- NCT03589612
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Hacettepe University
Athletic Performance, Physical Fitness
Trunk Muscle Endurance and Flexibility as Determinants of Athletic Performance in Elite Adolescent Tennis Players
This study aims to examine how trunk (core) muscle endurance and flexibility relate to athletic performance in elite adolescent tennis players aged 11-18 years.
- Conditions
- Athletic Performance, Physical Fitness, Sports Performance, Trunk Muscle Function
- Trial name
- NCT07447765
- Testing
- Physical Performance Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Rehabilitation, Training
The Effect of Modified Stepping Trainings in Frailty Elderly With Physical Performance- a Prospective Randomized Controlled Trial
This single-blind, randomized controlled trial compared the effects of modifiled stepping exercise training on flat step and unstable step on the functional outcomes in community-dwelling older adults.
- Conditions
- Rehabilitation, Training, Respiratory Muscle Strength
- Trial name
- NCT06505083
- Testing
- modified stepping trainings
- Where
- Thailand
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Chonticha Kaewjoho
Healthy Aging, Exercise Therapy
Land vs. Water Exercises on Performance and Swimming Behavior in Older Adults
This study aims to investigate the effects of an 8-week combined land and aquatic exercise program (conducted 3 days per week) on physical performance, recreational swimming behaviors, and water-related risk perceptions in older…
- Conditions
- Healthy Aging, Exercise Therapy, Resistance Training, Hydrotherapy
- Trial name
- NCT07784205
- Testing
- 8-Week Beach and Aquatic Exercise Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Eskisehir Technical University
Muscle Architecture
Effect of Eccentric Exercise on Musculus Triceps Surae Muscle Architecture, Muscle Strength, and Performance
This study investigates the architecture, muscle strength, and performance of skeletal muscles. Skeletal muscles constitute a mass of muscle fascicles connected to bones via tendons.
- Trial name
- NCT06573879
- Testing
- Eccentric Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medipol University
Oxidative Stress, Muscle Strength
The Effects of Antioxidant Supplementation on Multiple Endurance Race Performance, Physiology, and Recovery.
Thirty active male and female athletes will be recruited for the study. Subjects will be examined at baseline for VO2max performance.
- Conditions
- Oxidative Stress, Muscle Strength, Resistance Training, Body Composition
- Trial name
- NCT04314596
- Testing
- Cross Training Course, Oceanix
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Applied Science & Performance Institute
Healthy Volunteers, Neuromuscular Function
Eco-guided Neuromodulation of the Femoral Nerve on the Performance of Amateur Athletes.
This randomized crossover study aims to evaluate whether different percutaneous electrical nerve stimulation (PENS) protocols produce changes in neuromuscular performance in healthy adults.
- Trial name
- NCT07719179
- Testing
- Theta Burst Protocol, 10-10-10 Protocol, 5-55 Protocol
- Where
- Spain
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Psychological Phenomena: Central Fatigue
Impact of Varying Doses of Amino Acids on Exercise, Muscular and Mental Performance
A number of studies have shown that ingestion of crystalline amino acids, in particular branched chain amino acids (BCAA) can affect endurance performance, markers of muscle damage, and possibly mental focus.
- Trial name
- NCT01215396
- Testing
- AminoVital Amino Acid formulation, Amino Vital Amino Acid formulation
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- McMaster University
Exercise Performance, Supplementation
The Effect of Acute Beetroot Juice Supplementation on Anaerobic Performance in Football Players
The aim of this clinical trial is to examine the effects of two different natural fruit-vegetable blend beverages on short-duration, high-intensity exercise performance and muscle oxygenation in young male football players.
- Trial name
- NCT07048912
- Testing
- Beetroot Juice (BJ)
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Melike Nur Eroğlu
Healhty
Grape Seed Extract Supplementation on Cycling Time-to-Exhaustion Performance.
To address the physical fatigue and muscle recovery demands in endurance exercise, this study evaluates Grape Seed Extract (GSE) as a potential ergogenic aid.
- Trial name
- NCT07867977
- Testing
- Grape seed extract
- Where
- Taiwan
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Phototherapy
Effects of Light Emitting Diodes (LED) Therapy in Rugby Athletes
Therapy with light emitting diodes (LED) is a good resource to accelerate the recovery of the athlete and reduce muscle damage caused by exercise.
- Trial name
- NCT03728439
- Testing
- LED before, LED interval, LED after
- Where
- Brazil
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual de Londrina
Limb Girdle Muscular Dystrophy
A Gene Transfer Single Dose Study to Evaluate the Safety, Tolerability and Efficacy of SRP-9003 in Non-Ambulatory and Ambulatory Participants With Limb Girdle Muscular Dystrophy, Type 2E/R4 (Beta-Sarcoglycan [β-SG] Deficiency)
The primary purpose of this study is to evaluate the safety of SRP-9003 and to quantify expression of β-SG in the skeletal muscle of participants with limb-girdle muscular dystrophy, type 2E/R4 (LGMD2E/R4).
- Trial name
- NCT05876780
- Testing
- SRP-9003
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Sarepta Therapeutics, Inc.
High-intensity Strenght Training in Normoxia (H-N), Low-intensity Strenght Training in Normoxia (L-N)
Normobaric Hypoxia as a Strength Training Intensity Amplifier in Ice Hockey Players: Effects on Anaerobic Performance and Muscle Contraction Properties
The goal of this research study is to investigate the effects of resistance training performed under normobaric hypoxia (simulated altitude conditions) on anaerobic performance, lactate clearance, and muscle contractility in…
- Conditions
- High-intensity Strenght Training in Normoxia (H-N), Low-intensity Strenght Training in Normoxia (L-N), High-intensity Strenght Training in Normobaric Hypoxia (H-H), Low-intensity Strenght Training in Normobaric Hypoxia (L-H)
- Trial name
- NCT06930027
- Testing
- Resistance Training (High-Intensity), Resistance Training (Low-Intensity), Normobaric Hypoxia
- Where
- Poland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Jerzy Kukuczka Academy of Physical Education in Katowice
Sports Nutritional Physiological Phenomena
Blood, Muscle and Exercise Responses to Sodium Bicarbonate Supplementation
The aim of this study is to evaluate the changes in activity of transporters of H+ (monocarboxylate transporters; MCT1, MCT4, NHE) following sodium bicarbonate supplementation and subsequent exercise performance.
- Trial name
- NCT03505970
- Testing
- Sodium bicarbonate, Maltodextrin
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo