Clinical trials: Muscle Physiology
Fibromyalgia
Combined Effects of Progressive Relaxation Exercises and Aquatic Therapy in Fibromyalgia.
Fibromyalgia, a chronic pain disorder, presents a significant challenge in healthcare due to its widespread musculoskeletal pain, tenderness, and a spectrum of associated symptoms.
- Trial name
- NCT06460636
- Testing
- progressive muscle relaxation therapy, aquatic therapy
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Arthroplasty
Preoperative Pain, Function, and Activity for Total Hip and Knee Arthroplasty Patients
This study wish to show if the preoperative level of pain, function or activity for hip and knee arthroplasty patients has any predictive value of the time it takes to fulfill the well-defined discharge criteria.
- Trial name
- NCT01248039
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Hvidovre University Hospital
Caloric Restriction, Body Composition
Long-Term Effects of Semaglutide on Body Composition and Performance in Running
Semaglutide, a GLP-1 receptor agonist, has demonstrated significant weight-loss effects in people with obesity and/or type 2 diabetes, but its impact on exercise performance among lean, fit athletes remains unknown.
- Conditions
- Caloric Restriction, Body Composition, Performance
- Trial name
- NCT07874932
- Testing
- Semaglutide (SEMA)
- Where
- Denmark
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Morten Hostrup, PhD
Pelvic Floor, Functional Constipation
The Effect of Pelvic Floor Muscle Training in Functional Constipation
The aim of this study is to examine the effect of individualized pelvic floor muscle training on symptoms, core muscle function, and quality of life in patients with functional constipation.The research is being conducted at the…
- Conditions
- Pelvic Floor, Functional Constipation, Biofeedback, Chronic Constipation
- Trial name
- NCT07603414
- Testing
- Lifestyle change training, Diaphragmatic Breathing Exercise, Pelvic Floor Muscle Training
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Selin Koşan
Stem Cell Transplantation
Physical Functions in Allogeneic-HSCT Candidates
Physical inactivity and impairments in physical functions have been observed in patients due to hematological malignancy itself and treatments of chemotherapy, radiotherapy, corticosteroids.
- Trial name
- NCT03915249
- Volunteers
- 49 people
- Sponsor
- Gazi University
Muscle Weakness, Muscle Atrophy
Effect of Neuromuscular Electrical Stimulation Combined With Blood Flow Restriction on Muscular and Cardiovascular Function
Neuromuscular electrical stimulation (NMES) has recently been combined with blood flow restriction (BFR) in controlled trials and has shown increased muscular strength and size compared with NMES and BFR on their own.
- Trial name
- NCT03662555
- Testing
- Neuromuscular electrical stimulation
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- St. Mary's University, Twickenham
Muscular Atrophy, Spinal
A Study Evaluating the Effectiveness and Safety of Risdiplam Administered in Pediatric Patients With Spinal Muscular Atrophy Who Experienced a Plateau or Decline in Function After Gene Therapy
This is an open-label, single-arm, multicenter clinical study to evaluate the effectiveness and safety of risdiplam administered in pediatric participants with SMA and 2 SMN2 copies who previously received onasemnogene…
- Trial name
- HINALEA 2 (NCT05861999)
- Testing
- Risdiplam
- Where
- 17 sites in United States, Germany and 4 more
- Volunteers
- 19 people
- Sponsor
- Hoffmann-La Roche
Vitamin D Deficiency, Sarcopenia
Impact of Vitamin D on 25-hydroxyvitamin D Levels and Physical Function
This one-year study will test the hypothesis that supplementation with vitamin D will improve lower extremity muscle performance in older men and women with vitamin D insufficiency.
- Trial name
- NCT02293187
- Testing
- vitamin D3
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tufts University
Subacromial Impingement Syndrome
Effects of KT and Scapular Stabilization Exercises.
The distance between the acromion bone and the head of the humerus narrows in subacromial impingement syndrome. This narrowing leads to the compression of sensitive structures and results in pain and decreased functional…
- Trial name
- NCT06688214
- Testing
- Kinesio Taping treatment, Scapular Stabilization Exercises
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Sehat Medical Complex
INSTRUMENT ASSISTED SOFT TISSUE MOBILIZATION
Role of Soft Tissue Therapy in Plantar Fasciitis
Plantar Fasciitis (PF) is a frequently and commonly reported heel pain present in every age with multifactorial etiology. It is the most common reason for constant heel pain in adults affecting both young active and older…
- Trial name
- NCT05256433
- Testing
- Group-A, Group-B
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Ziauddin University
Lower Urinary Tract Symptoms, Sexual Function
Pelvic Floor Muscle Exercise During Pregnancy
This study was conducted to evaluate the effects of pelvic floor muscle exercises during pregnancy on sexual function, lower urinary tract symptoms and birth process.
- Trial name
- NCT06279455
- Testing
- Pelvic Floor Muscle Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Hyponatremia
Impact of Hyponatremia on Muscle Strength, Gait and Cognitive Function
In this study patients with hyponatremia, defined as a serum sodium < 126 mmol/L on admission to the hospital will be tested for muscular power by use of a hand grip dynamometer, for cognitive function by use of the…
- Trial name
- NCT04020926
- Where
- Switzerland
- Volunteers
- 8 people
- Sponsor
- Bürgerspital Solothurn
Stroke, Spasticity, Muscle
Analysis of the Correlation Between Ultrasound Imaging and Functional Parameters in the Medial Gastrocnemius Muscle in Post-stroke Patients With Spasticity in the Lower Limb
The goal of this observational study is to understand the impact of spasticity on muscle changes and functional performance in stroke patients with lower limb spasticity in comparison to non-stroke individuals.
- Trial name
- US-function (NCT06411587)
- Testing
- Ultrasound imaging and functional assessment
- Where
- Spain
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Muscle Fatigue, Muscle Strength
Short Term Omega-3 Supplementation on Performance
Nerves are the rate limiting factor that control muscle function. However, it is unknown if a nutritional supplement can change the nerve-muscle interaction, and therefore alter human performance.
- Trial name
- NCT02014233
- Testing
- Omega-3, Olive oil
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Torticollis Congenital
TAMO Therapy Versus Postural Control Exercise in Children With Congenital Muscular Torticollis
A randomized control trial was conducted through convenient sampling. 18 subjects were randomly allocated into two groups, group A received postural control exercises in addition to conventional therapy, while Group B received…
- Trial name
- NCT06015555
- Testing
- TAMO, Postural Control exercises
- Where
- Pakistan
- Volunteers
- 18 people
- Sponsor
- khadija liaquat
Spinal Muscular Atrophy Type 3
Whole Body Vibration Therapy in Children With Spinal Muscular Atrophy
Spinal muscular atrophy (SMA) are one of the common physical disabilities in childhood. For SMA, progressive muscle weakness and early fatigue hamper the mobility of the sufferers.
- Trial name
- NCT03056144
- Testing
- whole body vibration therapy
- Where
- Hong Kong
- Volunteers
- 1 people
- Sponsor
- The Hong Kong Polytechnic University
Multiple Sclerosis, Urinary Incontinence
Effects of Spinal Stabilization on the Pelvic Floor in Women With Multiple Sclerosis
The purpose of this study was to investigate the effects of spinal stabilization exercises focusing on the pelvic floor on core stability, urinary symptoms and pelvic floor muscle function in women with Multiple Sclerosis and…
- Conditions
- Multiple Sclerosis, Urinary Incontinence, Lower Urinary Tract Symptoms
- Trial name
- NCT07074587
- Testing
- Pelvic floor muscle exercises, Spinal stabilization exercises focusing on the pelvic floor + Pelvic floor muscle exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people
- Sponsor
- Abant Izzet Baysal University
Duchene Muscular Dystrophy
Home-Based Tele-Rehabilitation for Respiratory Function in Children With Duchenne Muscular Dystrophy
This study evaluates the feasibility and preliminary clinical effects of a home-based tele-rehabilitation program aimed at improving respiratory function in children with Duchenne Muscular Dystrophy (DMD).
- Trial name
- NCT07629284
- Testing
- Home-Based Respiratory Telerehabilitation Program
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- Samsung Medical Center
Fibromyalgia
Development of Treatments Aiming at Improvement of Function in Patients With Chronic Widespread Pain
The study aims to evaluate the effects of adding supervised exercise in supplement to an educational self-management program, and to determine which subgroups would gain effects of the treatment.
- Trial name
- NCT00545649
- Testing
- Exercise and education, Education
- Where
- 3 sites in Sweden
- Volunteers
- 164 people
- Sponsor
- Göteborg University
Sarcopenic Obesity, Sarcopenia
Lifestyle Modifications for the Treatment of Sarcopenic Obesity
This study evaluates the addition of a high-protein energy-restricted diet to exercise in the treatment of sarcopenic obesity in people aged 65 and over.
- Conditions
- Sarcopenic Obesity, Sarcopenia, Obesity
- Trial name
- NCT02379026
- Testing
- Protein Drink/Diet, Exercise, Vitamin D3
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Queen Margaret University
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