Clinical trials: Muscle Protein Synthesis
Healthy Adult Participants
Yeast Protein for Muscle Mass
Protein supplementation is said to be one of the cost-efficient and practical strategies to meet protein needs for growth and exercise, and can help maximize muscle gain from resistance exercise.
- Trial name
- NCT07561619
- Testing
- Yeast Protein, Resistance Training Exercises, Whey Protein
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Injuries, Musculoskeletal Pain
Translation and Psychometric Validation of an Italian Version of the Dance Functional Outcome Survey DFOS-IT
Study Design: Evaluation of the psychometric properties of a translated, culturally adapted questionnaire. Objective: Translating, culturally adapting, and validating the Italian version of the Dance Functional Outcome Survey…
- Conditions
- Injuries, Musculoskeletal Pain, Low Back Pain, Lower Limb Injury
- Trial name
- DFOS-IT (NCT03918876)
- Where
- Italy
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- Angela Contri
Age-related Degenerated Disease
Relationships Between Quality of Ageing and Age-related Degenerated Disease (Compalimage)
This project aims to assess the impact of chronic micro-inflammation on age-related loss of muscle (sarcopenia) and bone (osteopenia).
- Trial name
- Compalimage (NCT00862615)
- Testing
- Measurement of muscle protein synthesis using stable isotopes and muscle biopsies.
- Where
- France
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Muscle Atrophy, Aging
The Impact of Energy Intake and Short-term Disuse on Muscle Protein Synthesis Rates and Skeletal Muscle Mass in Middle-aged Adults.
In healthy middle-aged men and women, what is the effect of dietary energy restriction and energy surplus on daily muscle protein synthesis rates and muscle morphology, compared to energy balance, during free-living and…
- Conditions
- Muscle Atrophy, Aging, Energy Malnutrition Protein
- Trial name
- PIE (NCT04900701)
- Testing
- Energy status
- Where
- 2 sites in United Kingdom
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Cancer
Effects of Nutritional Supplementation (Product 4808) on Acute Skeletal Muscle Protein Synthesis in Cancer Patients
The purpose of the study is to compare two different nutritional supplements with respect to their effect on building muscle, and to determine the factors that control the rate at which muscle tissue can be produced in subjects…
- Trial name
- NCT00446888
- Testing
- Standardized Meals for Diet Stabilization, Forticare, Product 4808
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Arkansas
Sarcopenia, Muscle Hypotrophy
Systemic Hormones and Muscle Protein Synthesis
This study evaluates the effect of increase in testosterone levels in older males and the effects of decrease in testosterone levels in young males on muscle protein synthesis.
- Conditions
- Sarcopenia, Muscle Hypotrophy, Muscle Atrophy
- Trial name
- NCT03054168
- Testing
- Sustanon 250, Zoladex
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Obesity & Overweight, Women
Effect Of Whole or Skimmed Milk Greek Yogurt on Integrated Muscle Protein Synthesis, Glucose Homeostasis, and Cognition in Post-Menopausal Women
The study will examine the impact of adding two servings per day of skimmed or whole milk Greek yogurt on integrated muscle protein synthesis (iMPS), blood sugar control, and cognition in post-menopausal women with overweight and…
- Conditions
- Obesity & Overweight, Women, Menopause
- Trial name
- NCT07705724
- Testing
- Skimmed vs Whole Milk Greek Yogurt
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Muscle Metabolism
The Effect of a Plant-blend Protein Isolate on Post-exercise Myofibrillar Protein Synthesis
Dietary protein ingestion is required to maximise the anabolic response during the recovery from resistance exercise. Whey protein is considered the optimal dietary strategy to maximise post-exercise muscle protein synthesis, but…
- Trial name
- NCT06129513
- Testing
- Bilateral resistance exercise, Whey protein, Plant-blend protein
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Inflammaging, Sarcopenia
Inflammaging and Muscle Protein Metabolism
The development of a low-grade, chronic, systemic inflammation observed in the elderly (inflammaing) has been associated with increased risk for skeletal muscle wasting, strength loss and functional impairments.
- Trial name
- NCT03308747
- Testing
- Instantized Whey Protein Isolate
- Where
- Greece
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Myofascial Pain Dysfunction Syndrome, Trigger Point Pain, Myofascial
Validity, Reliability of Neck Disability Index in Albanian
To translate and validate the Cervical Disability Index (NDI) into Albanian for use in the Albanian-speaking population
- Trial name
- NDI (NCT06833359)
- Testing
- Observation
- Where
- Spain
- Volunteers
- 582 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Healthy Volunteers, Female
Progesterone and Muscle Protein Synthesis in Premenopausal Women (MP4-MPS)
The goal of this clinical trial is to learn if micronized progesterone (PROMETRIUM®) influences the muscle-building response to resistance exercise in healthy premenopausal women aged 18-30 years.
- Conditions
- Healthy Volunteers, Female, Progesterone, Premenopausal
- Trial name
- MP4 MPS (NCT07173361)
- Testing
- Micronized progesterone (oral capsules)
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- McMaster University
Muscle Soreness
Vegan Whey Protein for Muscle Anabolism and Post-exercise Recovery
This study will be a randomised, double-blind trial where participants will be randomly assigned to consume either a i) vegan whey protein; ii) a whey protein; or iii) a non-protein carbohydrate control supplement for 3 days…
- Trial name
- NCT07119749
- Testing
- Stable isotope tracer consumption, DXA scan, Controlled diet
- Where
- United Kingdom
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Diet, Healthy, Protein Deficiency
Protein and Performance (PROPER) in Endurance Athletes
The present study is a parallel group design with randomised allocation to either a 1) reduced protein diet (RP) or a 2) normal protein diet (NP).
- Trial name
- PROPER (NCT05426447)
- Testing
- Dietary intervention of reduced protein intake, Dietary intervention of normal protein intake
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Effect of Food
Nutrient Profile and Muscle Protein Synthesis in Response to Corn Bread Made From Refined Versus Whole Grain Maize Flour
The purpose of the study is to quantify and compare the serum nutrient and hormonal profile, and muscle protein synthesis rates, in response to consuming isonitrogenous amounts of a traditional East African meal, mung bean stew…
- Trial name
- PRO-CORN (NCT06662214)
- Testing
- Refined maize flour, Whole grain flour
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Muscle Atrophy
Beta-lactoglobulin, Immobilisation and Muscle Protein Synthesis
The objectives of this study are to: 1. Establish whether combined β-lactoglobulin supplementation and resistance training for 1 week prior to 5 days of limb immobilisation will attenuate the decrease in integrated free-living…
- Trial name
- NCT05496452
- Testing
- Beta-lactoglobulin, Carbohydrate
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- King's College London
Muscle Protein Synthesis
The Anabolic Properties of a Lipid-rich Pork Matrix
The amount and quality of skeletal muscle mass determines physical performance, but also a significant contributor to metabolic health.
- Trial name
- NCT05876299
- Testing
- 95.1% Lean Pork, 81.16% Lean Pork, Carbohydrate Beverage
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Sarcopenia
Assessing the Impact of "Super-whey" vs. Isonitrogenous Whey on Muscle Protein Synthesis
Skeletal muscle accounts for approximately 45-55% of total body mass in healthy adults and plays a pivotal role in whole-body metabolic health, locomotion and physical independence.
- Trial name
- ARLA-WHEY (NCT05701202)
- Testing
- Super-Whey protein, Isonitrogenous whey protein
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Menstrual Cycle Phase, Muscle Protein Synthesis
The Effect of Menstrual Cycle Phase on Muscle Protein Synthesis
The combination of dietary protein ingestion and resistance exercise are essential to increase muscle protein synthesis. The vast majority of studies assessing protein intake following resistance exercise in young adults has been…
- Trial name
- NCT06268678
- Testing
- Phase of the menstrual cycle
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Muscle Protein Synthesis, Whole-body Protein Balance
Essential Amino Acids and Protein Kinetics During Caloric Deprivation
The amount of essential amino acids (EAA) necessary to maximally stimulate muscle protein synthesis and optimize whole-body net protein balance during caloric deprivation has not been determined.
- Trial name
- NCT03372928
- Testing
- Standard EAA, High EAA
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Spinal Muscular Atrophy
Motor Function and Activity of Daily Life in Spinal Muscular Atrophy
This study will incorporate patients/ caregivers' perspectives to investigate the performance in daily activities of individuals with SMA and how it relates to their motor function abilities.
- Trial name
- NCT05931211
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital