Clinical trials: Muscle Soreness
Systemic Lupus Erythematosus, Muscle Pain
Laser Therapy for Patients With Systemic Lupus Erythematosus
Systemic lupus erythematosus (SLE) is a chronic, autoimmune disease that has detrimental effects on connective tissue and other organs.
- Conditions
- Systemic Lupus Erythematosus, Muscle Pain, Chewing Function
- Trial name
- NCT04453215
- Testing
- GaAlAs semiconductor diode laser device
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Dr. Merve Benli
Pain, Acute
Exploration of Gait Biomechanics and Muscle Pain of the Lower Extremity
This interventional study aims to test gait biomechanics in healthy individuals with and without experimental muscle pain in the lower extremities.
- Trial name
- NCT06411197
- Testing
- Hypertonic saline injection, Isotonic saline injection
- Where
- Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Kristian Kjær Petersen
Strength, Body Composition
Omega-3 Fatty Acid Supplementation to Enhance Performance
The goal of this intervention study is to determine if omega-3 fatty acid supplementation as compared to placebo improves performance in track and field athletes. The main questions it aims to answer are: 1.
- Conditions
- Strength, Body Composition, Muscle Soreness
- Trial name
- FO n-3 (NCT05924139)
- Testing
- Omega-3 fatty acid
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Baylor University
Human Immune Response
Effects of Palmar Cooling on the Human Immune System
This is a research study on human exercise that will investigate the immune system response post-exercise and how it relates to Delayed Onset Muscle Soreness (DOMS), and possible causes for DOMS.
- Trial name
- NCT07215338
- Testing
- Muscle Temperature Control
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Stanford University
Migraine, Pain, Shoulder
Effects of MTRPs Therapy in Migraine.
Case series, repeated-measures design, pilot study. Adult, female, migraine patients underwent seven Ischemic Compression Myofascial Trigger Points (IC-MTrPs) therapy sessions.
- Conditions
- Migraine, Pain, Shoulder, Trapezius Muscle Strain Left, Trapezius Muscle Strain Right
- Trial name
- MTRPs (NCT05646160)
- Testing
- Ischemic Compression of Myofascial Trigger Points (IC-MTRPs)
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Józef Piłsudski University of Physical Education
Muscle Fatigue, Trapezius Muscle Strain
Short Interventions to Prevent Trapezius Muscle Fatigue in Computer Work
This study is expected to demonstrate that during experimental days of seated computer work sustained and focalized low-level muscle activity contributes to the development of long-lasting fatigue effects (and thus possible…
- Trial name
- NCT03863340
- Testing
- interruptions of work tasks
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Migraine Disorders, Muscle Tenderness
Muscle Tenderness and Hardness in Migraine Patients
The aim of the study is to examine symptomatology, quantitative sensory test (QST) parameters, muscle tenderness and muscle hardness in migraine patients interictally and compare with healthy controls
- Conditions
- Migraine Disorders, Muscle Tenderness, Headache Disorders, Primary, Nervous System Diseases
- Trial name
- NCT03626805
- Where
- Denmark
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
PRP, Temporomandibular Disorder
The Platelet-Rich Plasma in the Therapy of Temporomandibular Disorders
The Platelet-Rich Plasma intramuscular injections into the masseter and temporalis muscle were performed to reduce painful temporomandibular disorder symptoms,such as myalgia, myofascial pain and myofascial pain with referrals.
- Conditions
- PRP, Temporomandibular Disorder, Myalgia, Bruxism
- Trial name
- PRP/TMD (NCT03371888)
- Testing
- Platelet-Rich Plasma intramuscular injections
- Where
- Poland
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Medical University of Silesia
Shoulder Pain, Healthy Volunteers
Sensory Processing and Musculoskeletal Shoulder Pain
The development of chronic pain is a common complication in shoulder pain conditions. Half of these type of patients exhibit persistent pain even after a period of six to twelve months from the start of their pain treatment.
- Trial name
- NCT05368649
- Testing
- Short-wave diathermy
- Where
- Argentina
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Gran Rosario
Delayed Onset Muscle Soreness
Dosing Interval Study of SST-0225 Topical Ibuprofen Cream in the Treatment of Delayed Onset Muscle Soreness
This is a Phase 2, prospective, randomized, dual-center, double-blind, placebo-controlled, parallel-group study designed to determine the dosing interval, efficacy and safety of SST-0225 (5.4 grams, applied up to 6 times in 24…
- Trial name
- DIS DOMS (NCT02339129)
- Testing
- SST-0225
- Where
- 2 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Strategic Science & Technologies, LLC
Acute Pain
A Study to Evaluate the Efficacy and Safety of K-285 Compared With Menthol Gel for the Treatment of Delayed Onset Muscle Soreness (DOMS) in the Lower Extremity
The purpose of this study to evaluate the efficacy and safety of K-285 compared with menthol gel for the treatment of delayed onset muscle soreness (DOMS) in the lower extremity.
- Trial name
- NCT04484428
- Testing
- K-285, Menthol
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Kowa Research Institute, Inc.
Ergonomics
Effect of Postural Correction Exercises on Shoulder Muscles Tenderness and Performance in Subjects Addicting Smartphones
smartphones have replaced most of the keypad phone products due to their small size and easy of portability. As a result, smartphone users experience an increase in musculoskeletal problems in the neck and shoulder.
- Trial name
- NCT05305807
- Testing
- Postural exercises
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Muscle Soreness, Muscle Weakness
Lumbosacral Muscle Sensitivity & Pressure Pain Threshold After Kettlebell Swings
The primary purpose of the study is to assess the muscle contractility and sensitivity of lumbar erector spinae, biceps femoris, and gluteus maximus short-term response to Tabata kettlebell swing protocol.
- Conditions
- Muscle Soreness, Muscle Weakness, Muscle Tenderness
- Trial name
- NCT05607212
- Testing
- Kettlebell Swing, Isometric Hold, Control
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Muscle Damage, Muscle Soreness
The Effects of Whey Protein Supplements on Markers of Exercise-induced Muscle Damage in Resistance-trained Individuals
Intense exercise can bring about various side effects to one's body. Less range of motion, increased pain sensitivity, increased muscle swelling, and decreased muscle strength can occur immediately after exercise.
- Trial name
- WheyProtein (NCT05100459)
- Testing
- Pasture-raised whey protein, Conventional whey protein
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Indiana University
Statin Myopathy
CoEnzyme Q10 in Statin Myopathy
Statins (such as simvastatin or Zocor) are the most effective and widely prescribed medications to lower cholesterol levels and reduce the frequency of heart attacks, cardiac deaths and strokes.
- Trial name
- NCT01140308
- Testing
- CoEnzyme Q10
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Hartford Hospital
Signs and Symptoms, Fever
Biomedical Signal Extraction From Symptom Descriptions: An Observational Registry Using the OpenGenome Platform
This registry prospectively collects anonymized free-text symptom descriptions submitted voluntarily by adults through the OpenGenome platform at opengenome.bio.
- Conditions
- Signs and Symptoms, Fever, Myalgia, Skin Diseases
- Trial name
- OGNOME-REG (NCT07578610)
- Testing
- OpenGenome AI Platform
- Where
- Germany
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- OpenGenome
Pain
Mirthful Laughter and Muscle Soreness / Pain
The purpose of this study is first to investigate the effect of a controlled intervention with a comedy video on pain tolerance in a social setting while quantitatively measuring laughter in a young healthy population…
- Trial name
- NCT02896075
- Testing
- 30 Minute Comedy Video, 30 Minute Documentary Video
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Muscle Soreness
A Study to Evaluate the Analgesic Properties of Topically Applied Menthol in Marathon Participants
The purpose of the research study is to better understand the factors that impact pain experience in adult (18+ years) marathon runners participating in the 2026 Chicago Marathon and to better understand if topically applied…
- Trial name
- NCT07873242
- Testing
- Observational, Non-Interventional Study
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
Oxidative Stress, Healthy
A Randomized, Double-Blind Study to Assess the Effect of a Postbiotic on Oxidative Stress and Exercise Performance
This is a prospective, randomized, placebo controlled, double-blind study to assess the effects of a postbiotic blend on exercise induced oxidative stress markers and exercise performance in healthy adult.
- Conditions
- Oxidative Stress, Healthy, Exercise-induced Muscle Damage, Exercise-induced Muscle Soreness
- Trial name
- PBE (NCT06795425)
- Testing
- Postbiotic Active Lifestyle Blend
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Myalgic Encephalomyelitis, Post-acute COVID-19 Syndrome
Inspiratory Muscle Training in ME/CFS and COVID-19 Survivors
Coronavirus-2019 (COVID-19) is a viral disease leading to respiratory dysfunction, but it may also affect the brain and result in the development of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).
- Trial name
- Inspire ME (NCT05196529)
- Testing
- Inspiratory muscle training
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- York University