Clinical trials: Muscle Weakness
Sarcopenia, Covid19
Sarcopenia and Related Factors in Coronavirus Disease 2019 (COVID-19) Following Intensive Care
The primary aim of this study is to evaluate the patients who had pneumonia or severe acute respiratory distress syndrome (ARDS) due to COVID-19 in terms of sarcopenia and related factors following Intensive Care Unit (ICU).
- Conditions
- Sarcopenia, Covid19, Intensive Care Unit Acquired Weakness
- Trial name
- NCT05474157
- Testing
- Standard care treatment for COVID-19 in Intensive Care Unit
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Koç University
Chronic Kidney Disease, Renal Insufficiency, Chronic
Reliability of Muscle Strength and Activation Assessment Tools and Effects of an Online Therapeutic Exercise Program in Patients With Chronic Kidney Disease
This research aims to evaluate the reliability and reproducibility of muscle strength and activation measurement tools, including isokinetic dynamometry and surface electromyography, in patients with chronic kidney disease (CKD).
- Conditions
- Chronic Kidney Disease, Renal Insufficiency, Chronic, Muscle Weakness, Sarcopenia
- Trial name
- NCT07292311
- Testing
- Reliability Assessment, Online Therapeutic Exercise
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Extremadura
Smoking Cessation, Body Composition, Beneficial
The Effect of Cigarette Smoking / Smoking Cessation on Skeletal Muscle Mass, Strength and Functional Capabilities
Tobacco smoke is probably the single most significant source of toxic chemicals that humans are exposed to. Smoking is associated with a variety of pathological conditions such as cardiovascular and pulmonary diseases.
- Conditions
- Smoking Cessation, Body Composition, Beneficial, Muscle Weakness
- Trial name
- NCT02128048
- Testing
- Assessment of body composition and muscle function
- Where
- Israel
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Pelvic Floor Muscle Weakness, Stroke
Multimodal Pelvic Floor Rehabilitation in Chronic Stroke Survivors: Long-Term Efficacy, Optimal Protocols, and Adjunctive Therapies for Comprehensive Pelvic Floor Dysfunction.
Evaluate long-term efficacy of multimodal PFMT in chronic stroke survivors with PFD.
- Trial name
- RCT (NCT07420569)
- Testing
- Core PFMT: 8-12 contractions (6-10s hold), 3 sets/day, progressed over 16 weeks. • Group A (Standard PFMT): 3 supervised/week (weeks 1-8), 1/week (9-16) + home. • Group B (Intensified PFMT): 5/week, Core PFMT: 8-12 contractions (6-10s hold), 3 sets/day, progressed over 16 weeks.
- Where
- Uganda
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Iqra National University
Obesity, Overweight
Abdominal and Core Exercises on Respiratory Functions in Obese and Overweight Women (COREBREATH)
This study aims to examine the effects of an 8-week Pilates-based exercise program on breathing functions in overweight and obese women (BMI ≥ 25).
- Conditions
- Obesity, Overweight, Pulmonary Disease, Muscle Weakness
- Trial name
- COREBREATH (NCT07103499)
- Testing
- Pilates-Based Core and Breathing Exercise Program
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Muscle Weakness, Myalgia
Coenzyme Q10 in Older Athletes Treated With Statin Medications
The purpose of this study is to evaluate the effect of coenzyme Q10 administration in improving mitochondrial function as measured by anaerobic threshold in older athletes on a stable dose of statin medication.
- Conditions
- Muscle Weakness, Myalgia, Side Effects of Statins
- Trial name
- NCT01026311
- Testing
- Coenzyme q 10
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Richard Deichmann, MD
Quadriceps Muscle Weakness, Adductor Muscle Weakness
Ultrasound Guided Adductor Canal Block Versus Femoral Nerve Block for Quadriceps Strength and Fall-risk
Our objective was to determine if an ultrasound guided ACB can preserve quadriceps strength, thus minimizing weakness of knee extension compared with ultrasound guided femoral nerve block.
- Conditions
- Quadriceps Muscle Weakness, Adductor Muscle Weakness, Fall Risk
- Trial name
- NCT01655277
- Testing
- Ultrasound Guided Adductor Canal Block, Ultrasound Guided Femoral Nerve Block
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Skeletal Muscle Hypertrophy, Muscle Weakness
The Effects of Lifting Light or Heavy Weights on Muscle Growth and Strength in Trained Young Men
When practicing weightlifting regularly the body makes new proteins within the muscle. These new proteins can increase the size of the cells within the muscle to make them larger, a process called hypertrophy.
- Trial name
- NCT02139865
- Testing
- 30% 1RM, 80% 1RM
- Where
- 2 sites in Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- McMaster University
Poor Performance Status, Muscle Weakness
SR-WBV Training for Frail Elderly in the Skilling up Stage
This randomized controlled study aims to examine long term effects in the skilling up phase over 4 weeks on physical functional performance and strength of mechanical SR-WBV and dance therapy intervention in a frail elderly…
- Trial name
- NCT01704976
- Testing
- SR-WBV
- Where
- Switzerland
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Bern University of Applied Sciences
Cerebral Palsy, Muscle Hypertonia
Hypertonia in Patients With Cerebral Palsy
This study will classify types of hypertonia in patients with cerebral palsy and determine if the classifications are reasonable in relation to the functional task of walking. Hypertonia is an abnormal increase in muscle tension.
- Trial name
- NCT00123708
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Pelvic Floor Muscle Weakness, Sexuality
Effect of Pelvic Floor Muscle Exercise on Sexual Function
The goal of this evaluate the effect of pelvic floor muscle exercises on sexual function in women of reproductive age. A randomized controlled trial was conducted in a sample of women of reproductive age, 77 women were randomly…
- Trial name
- NCT06338371
- Testing
- Pelvic Floor exercise training
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Serap Tekbas
Dynapenia, Muscle Weakness
Effect Of The Presence Of Dynapenia On Posture, Spine Muscle Elasticity, Strength And Endurance In Young Adults
The aim of the present study was to determine the effect of dynapenia on posture, spinal muscle elasticity, strength and endurance in young adults.
- Conditions
- Dynapenia, Muscle Weakness, Sarcopenia
- Trial name
- NCT06621875
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aynur Ayazzade
Muscle Weakness
Effect of Forward Head and Rounded Shoulder Posture on Hand Grip Strength in Asymptomatic Young Adults
see if there is significant difference between subjects with forward head rounded shoulder posture and subjects with normal posture in hand grip strength in asymptomatic young adults see if there is significant difference between…
- Trial name
- FHRSP-RS-FHP (NCT03586440)
- Where
- Egypt
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Cairo University
Obesity, Insulin Sensitivity
Effect of Weight Loss on Intermuscular Adipose Tissue (IMAT) Signaling
The goal of this intervention study is to learn about how weight loss impacts molecular signaling of intermuscular adipose tissue (IMAT) in individuals with obesity.
- Conditions
- Obesity, Insulin Sensitivity, Muscle Weakness, Adiposity
- Trial name
- NCT06129110
- Testing
- Diet Weight Loss
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Spastic Paresis, Stroke
GOAT (Gait Observation of Achilles Tendon)
The purpose of this study is to evaluate the mechanical properties of the Achilles tendon (stiffness, length, volume) and the force production capacities of the gastrocnemius medialis muscle in patients with spastic paresis…
- Conditions
- Spastic Paresis, Stroke, Spinal Cord Injury
- Trial name
- GOAT (NCT07467382)
- Testing
- 3D Gait Analysis, Ultrasound, Dynamometry
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Hemiparesis, Ischemic Stroke
Functional Magnetic Resonance Imaging (fMRI) and Robot-Assisted Practice of Activities of Daily Living
The investigators will study motor recovery after robot-assisted therapy after stroke. A small clinical trial will be conducted to quantify the central nervous system changes associated with robotic or standard training, and…
- Conditions
- Hemiparesis, Ischemic Stroke, Chronic
- Trial name
- NCT00878085
- Testing
- Robot Therapy Device, Occupational Therapy
- Where
- 2 sites in United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Stroke
Stroke Rehabilitation Program Based on a Powered Lower Extremity Exoskeleton in Chile
This research will study the effects of a rehabilitation program assisted by a powered lower extremity exoskeleton in patients after stroke.
- Trial name
- NCT04228224
- Testing
- Robot-assisted training with a lower extremity powered exoskeleton (H3 Exoskeleton, Spain), Conventional gait rehabilitation
- Where
- Chile
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Corporación de Rehabilitación Club de Leones Cruz del Sur
Stroke
Instrumental Gait Analysis on People With Stroke After Rehabilitation With a Synchronized FES and Cycle Ergometer System
Functional electrical stimulation is a modality of motor rehabilitation that consists of the programmed application of bursts of electrical current to the affected neuromuscular region that aims to improve muscle strength…
- Trial name
- NCT04473391
- Testing
- Cycle-ergometer training assisted by FES for lower extremities
- Where
- Chile
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Corporación de Rehabilitación Club de Leones Cruz del Sur
Knee Osteoarthritis, Knee Arthritis
Rate of Torque Development and Voluntary Quadriceps Activation in Patients With Knee Osteoarthritis: A Quantitative Analysis Before and After a Single Session of Manual Physical Therapy
This is a randomized control trial to determine if there is a measurable change in voluntary quadriceps activation, RTD, pain, and function before and after a single session of manual physical therapy.
- Conditions
- Knee Osteoarthritis, Knee Arthritis, Knee Pain Chronic, Knee Deformity
- Trial name
- NCT04234282
- Testing
- Manual Physical Therapy
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jennifer Moreno Clinic
Frailty, Muscle Weakness
Effectiveness of Protein Supplementation on Frailty Improvement, Muscle Strength and Physical Performance Among Pre-Frail Elderly People
The goal of this randomized clinical trial is to study the effectiveness of protein supplements in frailty improvement, muscle strength, physical performance, energy intake and body composition of pre-frail elderly people.
- Conditions
- Frailty, Muscle Weakness, Physical Dependence, Weight Loss
- Trial name
- NCT05648617
- Testing
- SUSTINEX Hydrolyzed Whey Protein
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia