Clinical trials: Muscle Weakness | Patient
Stroke
Study of Neurophysiological Markers of Motor Recovery in Post-stroke Patients.
The aim of the study was to explore potential pathways for recovery and adaptation of neural pathways after stroke by examining electrical activity of the brain cortex and cortico-spinal excitability using transcranial magnetic…
- Trial name
- NCT06386627
- Testing
- Stimulus response task, Transcranial magnetic stimulation
- Where
- Russia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Skolkovo Institute of Science and Technology
Chronic Obstructive Pulmonary Disease, Muscle Weakness
Cholecalciferol Supplementation in Strengthening Inspiratory Muscles in Cholecalciferol-Deficient Patients With Chronic Obstructive Pulmonary Disease
This phase IIb randomized trial studies how well cholecalciferol (vitamin D3) supplementation works in strengthening inspiratory muscles in cholecalciferol-deficient patients with chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT02877641
- Testing
- Cholecalciferol, Laboratory Biomarker Analysis, Multivitamin
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Roswell Park Cancer Institute
Knee Osteoarthritis, Muscle Weakness
Knee Pressure Stimuli on Quadriceps Strength in Knee Osteoarthritis
The study aims at investigating the effects of a periarticular knee pressure stimulation on quadriceps strength and neuromuscular activity in subjects with knee ostearthritis.
- Trial name
- NCT05826236
- Testing
- Periarticular compression
- Volunteers
- 50 people
- Sponsor
- Istituto Clinico Humanitas
Muscle Weakness
Effect of EPA and HMB on Strength in ICU Patients
The investigators will determine if administration of HMB (hydroxymethylbutyrate) or EPA (eicosapentaenoic acid) will increase diaphragm and limb muscle strength for patients on breathing machines in an intensive care unit.
- Trial name
- NCT01270516
- Testing
- HMB, hydroxymethylbutyrate, EPA, eicosapentaenoic acid, Saline
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Gerald Supinski
Hemiparesis
Blood Flow Restriction Training on Upper Limb Performance
Background; Blood flow restriction training (BFRT) is a physical intervention that promotes many beneficial muscular activities and functions when low load/intensity is used in healthy and clinical populations.
- Trial name
- NCT06859905
- Testing
- blood flow restriction training, regular exercises
- Where
- Saudi Arabia
- Volunteers
- 70 people
- Sponsor
- University of Hail
Ankle Contracture, Critically Ill Intensive Care Unit Patients
Continuous Passive Motion to Prevent Ankle Contracture and Muscle Atrophy in Ventilated Patients
This clinical trial aims to evaluate whether continuous passive motion (CPM) can prevent ankle joint contracture and muscle atrophy in critically ill patients receiving mechanical ventilation in the ICU.
- Conditions
- Ankle Contracture, Critically Ill Intensive Care Unit Patients, Muscle Atrophy
- Trial name
- CPM-ICU (NCT07032051)
- Testing
- Continuous Passive Motion
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
ICU Acquired Weakness
Diagnosing Intensive Care Unit (ICU) Acquired Weakness
The goal of this study is to develop a non-invasive test to diagnose intensive care unit (ICU) acquired weakness that can be administered to both responsive and non-responsive patients.
- Trial name
- NCT04166630
- Testing
- Clinical Electrical Stimulator
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Emory University
Muscle Weakness, Critical Illness
Systematic Team Approach to Guide Early Mobilization in Surgical Intensive Care Unit Patients
The investigators hypothesize that by applying a validated algorithm to accomplish early mobilization in surgical intensive care unit (ICU) patients, these patients will achieve a higher level of mobility which translates to…
- Conditions
- Muscle Weakness, Critical Illness, Respiratory Insufficiency
- Trial name
- mSOMS (NCT01363102)
- Testing
- SOMS
- Where
- 5 sites in United States, Austria and 1 more
- Volunteers
- 200 people
- Sponsor
- Massachusetts General Hospital
Stroke Rehabilitation
Self-modulated Functional Electrical Stimulation in Chronic Stroke Patients With Severe and Moderate Upper Limb Paresis
The study aims at demonstrating the efficacy of self-modulated functional electrical stimulation (SM-FES) in promoting upper-limb (UL) motor recovery in chronic stroke patients with severe and severe-moderate paralysis.
- Trial name
- SM-FES (NCT04014270)
- Testing
- Self-modulated functional electrical stimulation (SM-FES), Standard Care
- Where
- 4 sites in Switzerland
- Volunteers
- 29 people
- Sponsor
- Intento SA
COVID-19, ICU Acquired Weakness
One-Year Quality of Life and Functional Prognosis of COVID-19 Patients in Post-ICU Setting
The COVID-19 disease has been subject to numerous publications since its emergence. Almost 20% of people suffering from COVID-19 develop severe to critical symptoms and require hospitalization, often in Intensive Care Unit (ICU).
- Conditions
- COVID-19, ICU Acquired Weakness, Weaning Failure
- Trial name
- COVENTRY (NCT04373811)
- Testing
- Lung ultrasound, Muscle ultrasound
- Where
- 3 sites in France
- Volunteers
- 65 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Stroke, Hemiparesis of the Upper Limb Following Stroke
Neurophysiological and Behavioral Effects of Combining Transcranial Direct Current Stimulation (tDCS) and Modified-Constraint Induced Movement Therapy (mCIMT)
This clinical trial aims to evaluate the effect of different types of tDCS modulation with mCIMT in improving affected upper-limb motor function for stroke patients.
- Conditions
- Stroke, Hemiparesis of the Upper Limb Following Stroke, Stroke Rehabilitatiom
- Trial name
- tDCS and mCIMT (NCT06786000)
- Testing
- Anodal tDCS combined with mCIMT, Cathodal tDCS combined with mCIMT, Bihemispheric tDCS combined with mCIMT
- Where
- Saudi Arabia
- Volunteers
- 300 people
- Sponsor
- King Saud University
Stroke, Hemiparesis
Proprioceptive Stimulation With Manual Bilateral Rhythmic Exercise in Post-stroke Patients
The purpose of this study is to evaluate the effect of the repetitive proprioceptive bilateral stimulation for the early recovery of the voluntary muscle contraction in stroke patients.
- Trial name
- BAT (NCT03155399)
- Testing
- Proprioceptive based training (PBT), Conventional neuromotor treatment (CNT).
- Where
- Italy
- Volunteers
- 34 people
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Stroke, Chronic Stroke
Comparison of EEG-Timed vs. Repetitive Robot Therapy for Chronic Stroke
This clinical trial compares two types of robotic hand rehabilitation-brain wave (EEG)-timed therapy versus simple repetitive therapy-to see which is more effective for recovering hand function in patients with chronic stroke.
- Conditions
- Stroke, Chronic Stroke, Hemiparesis
- Trial name
- NCT07459725
- Testing
- EEG-Timed Robot Operation, Repetitive Robotic System
- Volunteers
- 20 people
- Sponsor
- Seoul National University Bundang Hospital
Covid19
Evaluation of Muscle Strength, Functional Independence, Myalgia, Fatigue and Dyspnea in COVID-19 Infection
Coronavirus disease 2019 (COVID-19) is a serious, acute infectious disease caused by Serious Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). COVID-19 can manifest itself in a wide variety of clinical scenarios.
- Trial name
- NCT04784546
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Gazi University
ACL Reconstruction, ACL Surgery
Post Operative Use of Neuromuscular Electrical Stimulation (NMES) Device for ACLR Patients
This study is being conducted to learn about how neuromuscular electrical stimulation (NMES) in addition to standard of care aids in the recovery of muscle strength in patients undergoing ACLR procedure.
- Conditions
- ACL Reconstruction, ACL Surgery, ACL Injury, Electrotherapy
- Trial name
- NCT07171346
- Testing
- Zynex NexWave Electrotherapy Device
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Kansas Medical Center
Muscle Weakness, Gait, Unsteady
High Intensity Interval Training in Geriatrics
This is a pilot study for evaluating the feasibility of using High Intensity Interval Training in geriatric hospitalized patients compared to the standard current rehabilitation practice.
- Trial name
- HIITERGY (NCT02318459)
- Testing
- high intensity interval training-HIIT, Traditionnal group rehabilitation
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University Hospital, Geneva
Stroke, Upper Extremity Paresis
Rhythmic Initiation vs Isometric Training for Arm Recovery After Stroke
Stroke is a leading cause of long-term disability worldwide. Many stroke survivors experience persistent weakness, loss of motor control, and poor coordination in their upper limb, which limits their ability to perform daily…
- Trial name
- RIITSTROKE (NCT07598435)
- Testing
- Rhythmic Initiation (PNF technique), Isometric Resistance Training
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- University of Faisalabad
CVA (Cerebrovascular Accident), Paresis
Robotic Enhanced Error Training of Upper Limb Function in Post-stroke Patients
Background: Stroke is a common cause of morbidity, including paresis, and stroke survivors often have reduced function in their paretic arm.
- Trial name
- NCT05174676
- Testing
- Dextreme
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Reuth Rehabilitation Hospital
Telemedicine, Muscular Dystrophies
Telerehabilitation in Proximal Muscle Weakness
The aim of our study is to investigate the effectiveness of two exercise programs supervised by a physiotherapist, performed in the hospital or at their home via electronic connection in a group of LGMD and SMA patients.
- Conditions
- Telemedicine, Muscular Dystrophies, Proximal Myopathy
- Trial name
- NCT04392518
- Testing
- exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people
- Sponsor
- Koç University
Copd, Muscle Weakness
Mechanical Muscle Proprieties in Patient with COPD
This study aims to determine if patients with Chronic Obstructive Pulmonary Disease (COPD) exhibit altered muscle properties (specifically changes in tone and stiffness) in both their respiratory muscles and skeletal muscles when…
- Conditions
- Copd, Muscle Weakness, Muscle Weakness Condition
- Trial name
- NCT06410950
- Testing
- MyotonPRO Assessment of Muscle Biomechanical Properties
- Where
- Romania
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Spitalul Clinic de Boli Infecțioase și Pneumoftiziologie Dr. Victor Babeș Timișoara