Clinical trials: Muscular Disorders, Atrophic
Sarcopenia, Osteoporosis
Acetaminophen and Impaired Musculoskeletal Adaptations to Exercise Training
The purpose of this study is to determine if taking the pain reliever acetaminophen (ACET) interferes with some of the benefits of weight lifting on muscles and bone density in older men.
- Conditions
- Sarcopenia, Osteoporosis, Aging
- Trial name
- NCT01083901
- Testing
- Resistance training
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Wheelchair Mobility, Manual Wheelchair Skills Training
Wheelchair Skills Training for People with ARSACS and DM1
Wheelchairs (WC) are often provided to people with ARSACS and MD1 when they are not able to walk anymore. However, giving someone a MWC alone does not guarantee they will use it safely or properly.
- Conditions
- Wheelchair Mobility, Manual Wheelchair Skills Training, ARSACS, Myotonic Dystrophy Type 1
- Trial name
- NCT06596850
- Testing
- Wheelchair Skills Training Program
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Laval University
Obesity
Evaluation of the Healthy Lifestyle Program on Cognitive Outcomes
The goal of this study is to conduct a program of pilot research aimed at evaluating the effect of an intensive lifestyle intervention on cognitive functioning in older adults with obesity and or obesity and sarcopenia.
- Trial name
- NCT03926481
- Testing
- Evaluate Healthy Lifestyle Program on cognitive outcomes
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Sarcopenia
Assessing the Efficacy of a Muscle Strength Training Intervention for Sarcopenia in Middle-aged and Elderly Individuals
Taiwan entered an aging society in 2018 and is projected to become a super-aged society by 2025. With the increasing elderly population, age-related diseases have become an urgent issue in modern society.
- Trial name
- NCT07554274
- Testing
- Resistance exercise
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Osteosarcopenia, Rheumatoid Arthritis (RA)
Rheumatoid Arthritis and Osteosarcopenia: Associated Factors
Our study is a cross-sectional study, and its aim is to compare and analyze the prevalence of sarcopenia and osteoporosis in patients with rheumatoid arthritis (RA) with a control group and to reveal the impact of sarcopenia on…
- Conditions
- Osteosarcopenia, Rheumatoid Arthritis (RA), Sarcopenia
- Trial name
- NCT06889415
- Testing
- Osteosarcopenia in Patients with Rheumatoid Arthritis, Osteosarcopenia in Healthy Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Konya Beyhekim Training and Research Hospital
Sarcopenia
A Study of the Intervention Effect of a Hybrid Exercise Program on Elderly With Sarcopenia
Sarcopenia is a geriatric condition characterized by a progressive decrease in skeletal muscle content and loss of muscle function.
- Trial name
- NCT05694117
- Testing
- self-determine sequence exercise program, resistance training, Taichi exercise and resistance training
- Where
- China
- Volunteers
- 392 people, healthy volunteers welcome
- Sponsor
- Northeast Normal University
Sarcopenia, Osteopenia
Effect of a Ghrelin Receptor Agonist on Muscle and Bone
Adults with low muscle mass also usually have low bone mass, making them vulnerable to falls, fractures and other injuries. This project will determine the effectiveness of treatment with a ghrelin receptor agonist in improving…
- Trial name
- NCT04021706
- Testing
- Anamorelin Hydrochloride
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Tufts University
Muscle Loss
Plyometric Exercises Versus Isometric Exercises With Theraband Elastic Band in Water Polo Players
Introduction: The improvement of strength affects muscle volume, dynamic stability and sports performance in water polo athletes.
- Trial name
- NCT03872076
- Testing
- Experimental, Control
- Where
- Spain
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Investigación en Hemofilia y Fisioterapia
Osteoarthritis of the Knee, Sarcopenia
Identification of Sarcopenia in Knee Osteoarthritis With Ultrasonography and Evaluation of Muscle Architecture Change by Ultrasonography After Isokinetic Exercise Program
The aim of this thesis; To define sarcopenia in knee osteoarthritis with ultrasonography and to evaluate changes in muscle structure in sarcopenia after isokinetic exercise application ultrasonographically.
- Trial name
- NCT05019820
- Testing
- Knee strengthening exercises with isokinetic dynamometer, Strengthening around the knees with home exercise programe
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sema Dağcı
Sarcopenia, Frailty
Implementation of ProMuscle in Daily Practice
Implementation of a previously shown (cost-)effective combined lifestyle intervention for community living older adults, ProMuscle, in at least four of the eight communities of the 'Foodvalley' in the Netherlands.
- Conditions
- Sarcopenia, Frailty, Aging Problems
- Trial name
- PUMP-fit (NCT05672004)
- Testing
- PUMP-fit strategy (implementation toolbox), Implementation as usual
- Where
- Netherlands
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Sarcopenia, Malnutrition
Evaluation of Sarcopenia-Related Malnutrition in Older Adults
Sarcopenia and malnutrition are two geriatric syndromes that are frequently seen in the elderly and have multifactorial etiology and severe clinical effects.
- Trial name
- NCT05122104
- Where
- Turkey (Türkiye)
- Volunteers
- 590 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Sarcopenia
HIF-1α Stabilization As a Novel Therapeutical Approach for Sarcopenia.
Age-related sarcopenia is associated with reduced mobility, functional decline and disability, falls, and mortality in the elderly.
- Trial name
- HIF2 (NCT06736249)
- Testing
- Sarcopenic group, Muscle harvesting
- Where
- Italy
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Sarcopenia in Elderly
Effects of Sarcopenia on Proprioception, Kinesiophobia, and Pressure Pain Threshold
The aim of this observational study is to reveal the effect of sarcopenia on cervical proprioception, kinesiophobia and pressure pain threshold in geriatric individuals living in a nursing home.
- Trial name
- NCT07269600
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Atılım University
Sarcopenia, Dynapenia
Omega-3 Supplementation and Resistance Training
The purpose of this project is to evaluate whether omega-3 fatty acid supplementation (combined eicosapentaenoic acid and docosahexaenoic acid [EPA/DHA] supplement) augments the effects of a 12-week resistance training program in…
- Conditions
- Sarcopenia, Dynapenia, Inflammation
- Trial name
- NCT02617511
- Testing
- Omega-3 Supplementation
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Sarcopenia
Effect of Nutrition Supplementation Combined With Resistance Exercise in Elderly With Sarcopenia.
The purpose of this study was determine whether milk or soy milk supplements combined with resistance exercise improved sarcopenia in the elderly.
- Trial name
- NCT05035121
- Testing
- milk supplement, soy milk supplement, resistance exercise
- Where
- Taiwan
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Aging, Sarcopenia
Effect of Creatine+HMB Supplementation in Physically Active Older Adults
Sarcopenia (SAR) is the loss of muscle strength and mass caused by aging. It is accompanied by a progressive decline in physical and cognitive abilities, increasing the risk of falls.
- Conditions
- Aging, Sarcopenia, Nutrition, Healthy
- Trial name
- CRESHARE (NCT05951439)
- Testing
- CRE + HMB
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad de Burgos
Osteoporosis, Sarcopenia
Comprehensive Risk Assessment and Prevention Plan of Osteoporosis and Sarcopenia for the Elderly Participating in Community-based Long-term Care Services
The purpose of this project is: 1. Provide the epidemiological data of the prevalence, incidence, and risk factors of osteoporosis and sarcopenia among the elderly in rural areas. 2.
- Conditions
- Osteoporosis, Sarcopenia, Frailty
- Trial name
- NCT05104034
- Testing
- Osteoporosis screening and treatment as needed, Sarcopenia, Exercise
- Where
- Taiwan
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Duchenne / Becker Muscular Dystrophy, Dystrophia Myotonica 1
Evaluation of the Role of miR-1 in the Pathogenesis and as a Biomarker in Muscular Dystrophies and Congenital Myopathies
The study aims to find out if a specific blood molecule called miR-1, can be used as a biomarker to track the health of patients with certain muscle diseases.
- Conditions
- Duchenne / Becker Muscular Dystrophy, Dystrophia Myotonica 1, Congenital Myopathies, Healthy Participants
- Trial name
- Dystro-miR1 (NCT07415837)
- Testing
- dosage of blood biomarker miR1
- Where
- France
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Sarcopenia
Insulin and Sarcopenia in the Elderly
Muscle loss with aging is a significant contributor to disability in older people. Our general hypothesis is that loss of muscle with aging, known as sarcopenia, may be due to inability of muscle to grow in response to insulin.
- Trial name
- NCT00690534
- Testing
- Insulin Regular, L-NMMA, Sodium Nitroprusside
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Duchenne Muscular Dystrophy (DMD)
Research of Biomarkers in Duchenne Muscular Dystrophy Patients
The purpose of this study is to identify potential biomarkers for the diagnosis, disease progression assessment and response to treatment in patients with Duchenne Muscular Dystrophy.
- Trial name
- IBISD (NCT01380964)
- Where
- France
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Genethon