Clinical trials: Muscular Hypertrophy
Skeletal Muscle
Leucine or Protein Supplementation and Resistance Training
The purpose of this study was to determine the effects of L-leucine (LEU) or different protein supplements standardized to LEU (~3.0 g/serving) on changes in body composition, strength, and histological attributes in skeletal…
- Trial name
- MPS (NCT03501628)
- Testing
- L-leucine + maltodextrin, Whey protein concentrate, Hydrolyzed whey protein concentrate
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Auburn University
Spinal Cord Injuries
Novel Intervention to Influence Muscle Plasticity in Veterans
The loss of muscle contraction (paralysis) removes an important stimulus for maintenance of overall health for individuals with complete spinal cord injury (SCI).
- Trial name
- NCT01093014
- Testing
- Low-force muscle stimulation, High-force muscle stimulation, Sequential low-force and high-force muscle stimulation
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- VA Office of Research and Development
Muscle Composition, Sarcopenia
Effects of Increased, Egg-Based Protein Intake on Muscle Composition,
This study is designed to assess the effect of a diet-controlled nutrition program utilizing an egg-based higher protein diet on muscle composition and size, and indices of metabolic health and markers of systemic inflammation in…
- Conditions
- Muscle Composition, Sarcopenia, Hypertrophy, Inflammation
- Trial name
- S25 (NCT01396915)
- Testing
- Dietary Protein Intake
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Purdue University
Resistance Exercise, Muscle Hypertrophy
Muscle Adaptations in Children and Adults Following Twelve Weeks of Flywheel or Weight Stack Resistance Exercise
The goal of this trial is to compare resistance exercise using traditional techniques and flywheel training to controls in healthy children ages nine to 13 and adults ages 18 to 50.
- Conditions
- Resistance Exercise, Muscle Hypertrophy, Skeletal Muscle, EMG
- Trial name
- KidREx (NCT06698055)
- Testing
- Flywheel Resistance Exercise, Weight Stack Resistance Exercise
- Where
- Sweden
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Björn Alkner
Skeletal Muscle Hypertrophy
Effects of a Multi-ingredient Supplement Study: a Randomized Controlled Trial in Men and Women
Resistance exercise training is a known stimulant for muscle protein synthesis (MPS) to occur, however the consumption of protein is also necessary to induce a shift towards a positive net protein balance.
- Trial name
- SRCT (NCT03525197)
- Testing
- Whey protein-based supplement, Collagen protein-based supplement
- Where
- 2 sites in Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- McMaster University
Resistance Training
Training-induced Muscle Strength and Its Role in Interface Pressure in Inelastic Compression
The present study will answer the following question: what are the effects of strength gain and muscle hypertrophy on interface pressure, static stiffness index, and working pressure amplitude in the elderly using inelastic…
- Trial name
- NCT05023642
- Testing
- resistance training
- Where
- 2 sites in Brazil
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Pró Circulação®
Hypertrophy
Mycoprotein, Resistance Training, and Hypertrophy
Protein is vital for the preservation of health and optimal adaptation to training. However, animal proteins come with economic and environmental issues.
- Trial name
- HAM (NCT03572127)
- Testing
- Diet
- Where
- United Kingdom
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Hypertrophic Cardiomyopathy, Heart Diseases
Comparison of the Effects of Inspiratory Muscle Training and Baduanjin Exercises in Hypertrophic Cardiomyopathy Patients
The study aims to compare the effects of inspiratory muscle training and Baduanjin exercises on pulmonary function, exercise capacity, and quality of life in patients with hypertrophic cardiomyopathy.
- Trial name
- NCT06490250
- Testing
- Inspiratory Muscle Training, Baduanjin Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Istanbul University - Cerrahpasa
Menstrual Cycle, Resistance Exercise
Menstrual Cycle Phase Based Training
The primary purpose of this study is to employ state-of-the-art methods to fill current knowledge gaps on the effects of the menstrual cycle on resistance exercise training adaptations.
- Trial name
- MCPBT (NCT05936424)
- Testing
- Unilateral Resistance Exercise Leg, Non-Exercise Control Leg
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- McMaster University
Menopause Related Conditions, Exercise Training
Effects of Estrogen on Muscle Gain During 12-weeks of Exercise in Post-menopausal Women
As females age and transition through menopause, the decline in oestrogen level profoundly affects skeletal muscle mass and function.
- Trial name
- HER-MUSCLE (NCT07617454)
- Testing
- Estrogel, Physical exercise
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mette Hansen
Exercise Training, Healthy
Why do People Respond Differently to Resistance Training?
It is well known that regular resistance training (RT) can have health benefits. However, considerable heterogeneity in RT responses has been observed.
- Conditions
- Exercise Training, Healthy, Skeletal Muscle Hypertrophy
- Trial name
- PreEx (NCT05874986)
- Testing
- Resistance training
- Where
- Finland
- Volunteers
- 393 people, healthy volunteers welcome
- Sponsor
- University of Jyvaskyla
Athletic Performance, Muscle Strength
Comparison of Velocity-Based and Traditional Strength Training in Youth Soccer Players
This study compared the effects of velocity-based strength training and traditional strength training on physical performance and muscle adaptations in youth soccer players.
- Conditions
- Athletic Performance, Muscle Strength, Resistance Training
- Trial name
- NCT07447258
- Testing
- Velocity-Based Training (10% Velocity Loss), Velocity-Based Training (20% Velocity Loss), Traditional Strength Training
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Engin Güneş Atabaş
Hypertrophy, Resistance Training
Quantification of Internal Training Load
The aim of this study is to determine whether the distribution of internal load predicts the distribution of muscle hypertrophy among hamstring heads after a 10-week resistance exercise program.
- Conditions
- Hypertrophy, Resistance Training, Muscle
- Trial name
- QUADRATURE (NCT06164249)
- Testing
- strength training
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Université de Nantes
Muscle Hypertrophy, Muscle Strength
Hip Thrust Versus Back Squat Training in Untrained Adults
This study compared the effects of two lower-body resistance training exercises - the barbell back squat and the barbell hip thrust - on muscle growth and strength in untrained young adults.
- Trial name
- HTS (NCT07760220)
- Testing
- Resistance training
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Auburn University
Bruxism, Sleep Bruxism, Adult
Comparison of Dry Needling and Two Botulinum Toxins for Bruxism
1. Aim: The aim of this study is to prospectively compare the clinical efficacy of Dry Needling (DN), Nabota (PrabotulinumtoxinA), and Dysport (AbobotulinumtoxinA) treatments on the thickness of masseter and anterior temporal…
- Conditions
- Bruxism, Sleep Bruxism, Adult, Awake Bruxism, Masseter Muscle Hypertrophy
- Trial name
- NCT07452510
- Testing
- Dry Needling (DN), PrabotulinumtoxinA, Abobotulinumtoxina
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Recep Tayyip Erdogan University
Resistance Training, Blood Flow Restriction (BFR) Training Effects
Strength Training With and Without Blood Flow Restriction on Shoulder Muscle Strength in Healthy Adults
The goal of this clinical trial is to compare two types of shoulder strength training: low-load training with blood-flow restriction (BFR) and high-load training without BFR. The study includes healthy adults.
- Trial name
- NCT07186231
- Testing
- Low-load resistance training with Blood flow Restriction, High-load resistance training.
- Where
- Portugal
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Alice Maria da Costa Carvalhais
Muscle Hypertrophy, Muscle Fibre Activation
Lower and Higher Load Resistance Exercise Protocols: Acute Muscle Activation and Skeletal Muscle Hypertrophy
How much weight an individual lifts per workout does not dictate the relative increase in muscle size the individual gains following weeks of training, which is contrary to current strength training dogma.
- Trial name
- NCT03991117
- Testing
- resistance exercise
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- McMaster University
Muscle Hypertrophy, Bone Mineral Density Loss
Combined Whey Protein and Collagen Supplementation in Resistance-Trained Men
This study tested whether taking whey protein together with collagen peptides would provide greater benefits for muscle and bone health compared to whey protein alone, collagen alone, or a placebo.
- Conditions
- Muscle Hypertrophy, Bone Mineral Density Loss, Resistance Training Adaptation
- Trial name
- NCT07171411
- Testing
- Whey Protein + Collagen, Whey Protein, Collagen Peptides
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Masseter Muscle Hypertrophy
Xeomin Cosmetic in the Management of Masseter
The goal of this study was to evaluate the efficacy and safety of two injection techniques in the management of masseteric hypertrophy using Xeomin Cosmetic.
- Trial name
- NCT03376464
- Testing
- Xeomin Cosmetic
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Erevna Innovations Inc.
Hypertrophy
Egg Consumption and Muscular Adaptations
Eggs may be a viable alternative to various types of supplemental proteins given its similar ratings on various measures of dietary protein quality.
- Trial name
- NCT04381390
- Testing
- Whole egg and resistance training, Egg whites and resistance training
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alexei Wong