Clinical trials: Musculoskeletal Injury Trauma
Chronic Pain
Study to Evaluate the Long-Term Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) in Patients Who Require Opioid Treatment for an Extended Period of Time
The primary objective of this study is to evaluate the safety of hydrocodone extended-release tablets when used over a 12-month period in patients with chronic pain, as assessed by adverse events, clinical laboratory results…
- Trial name
- NCT01223365
- Testing
- Hydrocodone ER
- Where
- 54 sites in United States
- Volunteers
- 330 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Shoulder Injury
Blood Flow Restriction Therapy Following Acute Shoulder Injury Patients
Atrophy and weakness of the shoulder are a common problem following treatment of a number of shoulder and elbow pathologies. Even with relatively short periods of reduced activity, the magnitude of muscle loss can be quite…
- Trial name
- BFR (NCT06223373)
- Testing
- Blood Flow Restriction
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Wake Forest University Health Sciences
Abdominal Trauma, Abdominal Injury
A Non-Traumatic Binder for Temporary Abdominal Wall Closure
At the end of most abdominal operations, the fascial layer is closed by stitching edges of the wound together. However, because of logistic and/or technical reasons or the patient's critical condition, the surgeon is forced to…
- Conditions
- Abdominal Trauma, Abdominal Injury, Abdominal Infection, Abdominal Sepsis
- Trial name
- ABRO (NCT03815370)
- Testing
- Experimental: ABRO™ Binder Arm
- Where
- 4 sites in Canada
- Volunteers
- 140 people
- Sponsor
- Unity Health Toronto
Brain Injury, Muscle Weakness
A Pilot Study of Rehabilitation Among Intensive Care Unit (ICU) Survivors: the RETURN Trial
Intensive care unit (ICU) hospitalization saves lives but often does so at a high personal cost to ICU survivors who frequently experience significant cognitive impairment and an array of physical and functional disabilities that…
- Trial name
- RETURN (NCT00715494)
- Testing
- Cognitive, physical, and functional rehabilitation
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Vanderbilt University
Osteoporosis, Postmenopausal, Osteoporosis
Quality of the Detection & Treatment of Osteoporotic Fractures in a Swiss Trauma Center
As a tertiary hospital the Traumatology department at the Kantonsspital Aarau looks after about 500 fracture patients hospitalized with an age over 50 years a year.
- Trial name
- NCT02157753
- Where
- Switzerland
- Volunteers
- 478 people
- Sponsor
- Kantonsspital Aarau
Burn Injury
The Effect of Acute Phase Treatment Approaches on Creatine Kinase and the Musculoskeletal System in Different Types of Burns
There are very few studies indicating the effect of acute phase treatment approaches on creatine kinase and the musculoskeletal system in the physiotherapy and rehabilitation process.
- Trial name
- NCT04417439
- Testing
- universal goniometer. evaluate the circumference measurement. The biochemical examination of CK (creatine kinase)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 37 people
- Sponsor
- Inonu University
Sarcoma, Muscle Tumor
Functional Muscle Transfers in Lower Limb Sarcoma: 3D Gait Analysis and Environmental Simulation
The purpose of this study is to assess patient's function after functional limb restoring surgery, performed after ablative tumour surgery or trauma.
- Conditions
- Sarcoma, Muscle Tumor, Muscle Loss
- Trial name
- NCT04911972
- Testing
- Functional muscle transfer
- Where
- United Kingdom
- Volunteers
- 27 people
- Sponsor
- NHS Greater Glasgow and Clyde
Non-specific Chronic Back Pain
Eye Movement Desensitization and Reprocessing (EMDR) in Non-specific Chronic Back Pain
The study explores the feasibility of Eye-Movement-Desensitization and Reprocessing (EMDR) in non-specific chronic back pain.
- Trial name
- LOGIN - EMDR (NCT01850875)
- Testing
- Eye-Movement-Desensitization-Reprocessing
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University Hospital Heidelberg
Musculoskeletal Pain, Musculoskeletal Injury
A New Experimental Model of Transient and Short-lasting Muscle Pain in Humans Based on Diathermy
This study evaluates the use of short-wave diathermy (SWD) as an novel experimental model to induce transient and intensity-controlled muscle pain by heating muscle tissue.
- Trial name
- NCT03573219
- Testing
- Short-wave diathermy
- Where
- Argentina
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- National Council of Scientific and Technical Research, Argentina
Rhabdomyolysis, Acute Kidney Failure
Plasma Neutrophil Gelatinase Associated Lipocalin Levels During Emergency Management of Rhabdomyolysis
This research project consists of a prospective diagnostic study conducted on patients with clinical suspicion of rhabdomyolysis admitted to the emergency rooms of the University Hospitals of Nimes, Montpellier, Paris, Nice and…
- Trial name
- NCT01544231
- Testing
- Plasma NGAL level
- Where
- 5 sites in France
- Volunteers
- 197 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Patellar Dislocation, Anatomic Abnormality
The Influence of Anatomic Deformities on the Clinical Efficacy in the Patients With Patellar Dislocation
All the data of patients with patellar dislocation will be collected to evaluate the anatomic deformities. The data includes X-ray, CT, MRI examinations, medical records, and physical examination information.
- Conditions
- Patellar Dislocation, Anatomic Abnormality, Trochlear Dysplasia, Femoral Anteversion
- Trial name
- NCT05243134
- Testing
- Collect the clinical data
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Peking University Third Hospital
Acromioclavicular Joint Dislocation
Tightrope Fixation of Acromioclavicular Joint Dislocation - a Prospective Series
Several surgical techniques are used for the treatment of acute acromioclavicular joint dislocations. The investigators investigate a new method using arthroscopic repair using the Tightrope fixation device.
- Trial name
- NCT01274884
- Testing
- Tightrope fixation
- Where
- Norway
- Volunteers
- 25 people
- Sponsor
- Sykehuset Asker og Baerum
Lumbar Spinal Stenosis, Carpal Tunnel Syndrome (CTS)
124I-Evuzamitide PET/CT Imaging In Patients With Lumbar Spinal Stenosis and Carpal Tunnel Syndrome
This clinical trial will use the amyloid-binding radiotracer, 124I-evuzamitide, to potentially detect amyloid, in the heart and elsewhere, in patients who have a history of lumbar spinal stenosis and/or carpal tunnel syndrome.
- Conditions
- Lumbar Spinal Stenosis, Carpal Tunnel Syndrome (CTS), Cardiac Amyloidosis
- Trial name
- NCT06907849
- Testing
- 124I-evuzamitide
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Tennessee Graduate School of Medicine
Spinal Cord Injuries
Feasibility Study for the Use of Low-magnitude, High Frequency Mechanical Stimulation of Bone in Persons With Spinal Cord Injury (SCI)
In persons with SCI, because of inherent considerations, the use of mechanical stimulation has not been studied to determine improvement in bone mass.
- Trial name
- NCT00882843
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Musculoskeletal Disorder
R2P Field Test of the EMS LiftKit: Validating Usability, Usefulness, Desirability, and Effects on Musculoskeletal Injuries in EMS Providers
The long-term goal of our research program is to reduce the high incidence of musculoskeletal injury associated with person-handling tasks performed by EMS providers/responders (NORA Public Safety Industry Sector).
- Trial name
- NCT05551143
- Testing
- LiftKit
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Transcutaneous Electric Nerve Stimulation, Chronic Low-back Pain
High Frequency RF Current Effects on Muscle Pain and Function
The purpose of this study is to examine the acute and chronic effects of high frequency electrical current transfer (frequently called "TECAR") on pain and functional movement in individuals with a musculoskeletal injury or pain.
- Conditions
- Transcutaneous Electric Nerve Stimulation, Chronic Low-back Pain, Hamstring Injury, Muscle; Injury, Quadriceps (Thigh)
- Trial name
- NCT05345015
- Testing
- Radiofrequency Energy Transfer, Transcutaneous Nerve Stimulation
- Where
- 2 sites in Greece
- Volunteers
- 200 people
- Sponsor
- Aristotle University Of Thessaloniki
Musculoskeletal Diseases, Median Nerve Disease
The Relationship Between Ultrasonographic Findings and Sleep Quality in Carpal Tunnel Syndrome
The aim of our study is to determine the relationship between disease severity and sleep quality in CTS patients and to compare the findings with healthy controls.
- Conditions
- Musculoskeletal Diseases, Median Nerve Disease, Carpal Tunnel Syndrome, Ultrasound
- Trial name
- NCT05742776
- Testing
- Assessment of Sleep Quality
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
Spinal Cord Injury, Paraplegia
Effects of Functional Electrical Stimulation on Spasticity, Quadriceps Muscle Strength and Functional Mobility in Individuals With Paraplegia
Spinal cord injury (SCI)-related paraplegia is a complex neurological condition characterized by motor impairment, increased spasticity, and significant functional limitations in daily activities.
- Conditions
- Spinal Cord Injury, Paraplegia, Spasticity, Neurorehabilitation
- Trial name
- FES-PAR-RCT (NCT07583576)
- Testing
- Conventional Neurorehabilitation, Functional Electrical Stimulation (FES) of Quadriceps Muscle
- Sponsor
- Istanbul Medipol University Hospital
Limbs Arthrosis, Non Arthrosic Limbs Arthralgia
Association of Transcutaneous Electrical Nerve Stimulation and Hypnosis
At Saint-Antoine's hospital, in CETD a multidisciplinary team takes care of patients with chronic pain. Free-drug techniques are available to reduce their consumption of analgesics.
- Conditions
- Limbs Arthrosis, Non Arthrosic Limbs Arthralgia, Chronic Lomboradiculalgia, Chronic Back Pain
- Trial name
- HYPTENS (NCT01944150)
- Testing
- Transcutaneous electrical nerve stimulation, Transcutaneous electrical nerve stimulation and hypnosis
- Where
- France
- Volunteers
- 72 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Low Back Pain, Musculoskeletal Injury
Does Self-efficacy Predict Outcomes Among U.S. Military Academy Cadets During Initial Entry Training?
Background: Lower back injuries are a common occurrence in athletes, sports programs, and in the military (Bengtsson, 2018; Lovalekar, 2021).
- Trial name
- NCT05453110
- Testing
- Deadlift Form Education
- Where
- United States
- Volunteers
- 903 people, healthy volunteers welcome
- Sponsor
- Keller Army Community Hospital