Clinical trials: Musculoskeletal Pain Disorder
Lateral Epicondylitis
Comparison of Muscle Energy Technique and Oscillating Energy Manual Therapy in Chronic Lateral Epicondylitis
Lateral epicondylitis (LE) is a painful musculoskeletal condition caused by overuse. The condition is also called tennis elbow because it affects 50% of tennis players, notably beginners learning the one-handed backhand.
- Trial name
- NCT05354167
- Testing
- muscle energy technique, oscillating manual energy therapy
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Osteoarthritis
Precision Assessment of Platelet Rich Plasma for Joint Preservation
Knee Osteoarthritis (OA) is a leading cause of premature disability in Veterans who develop knee OA at higher rates and younger ages than the population in general.
- Trial name
- NCT03460236
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- VA Office of Research and Development
Rheumatoid Arthritis
Validation of the French Version of the Health Assessment Questionnaire II (HAQ-II) for Rheumatoid Arthritis
The purpose of the study is to develop a validated French version of the HAQ-II questionnaire for rheumatoid arthritis.
- Trial name
- HAQ-II (NCT03249467)
- Where
- France
- Volunteers
- 129 people
- Sponsor
- Rennes University Hospital
Temporomandibular Disorders
Anterior Deprogrammers for Reducing Pain and Masticatory Muscles Tension
The study will be conducted in four groups of 20 patients in age of 20-30 years with complete dentition or single tooth loss in lateral regions, with masticatory muscle pain in the history or during examination and overuse and/or…
- Trial name
- Deprogrammer (NCT03180671)
- Testing
- Deprogramer Sliding Guide, Deprogrammer Dawson B-Splint, Deprogrammer Kois
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Lukasz Adamczyk
Rheumatoid Arthritis
A Study to Determine the Risk of Cancer in Rheumatoid Arthritis (RA) Patients Who Use Abatacept and Other Biologic Agents
An observational study to determine the risk of cancer associated with the use of abatacept and other biologic agents among rheumatoid arthritis patients
- Trial name
- NCT03670667
- Testing
- Non-Interventional
- Where
- United States
- Volunteers
- 1,132 people
- Sponsor
- Bristol-Myers Squibb
Inflammatory Bowel Diseases, Chronic Pain
Somatosensory Profiles in Individuals With Persistent Musculoskeletal Pain and Inflammatory Bowel Disease
This study evaluates nervous system hypersensitivity in individuals with inflammatory bowel disease (IBD) and experiences of ongoing musculoskeletal (MSK) pain.
- Conditions
- Inflammatory Bowel Diseases, Chronic Pain, Central Sensitization
- Trial name
- NCT03799471
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Craniosynostoses, Pain, Postoperative
Scalp Block Decreases Pain and Side Effects
Postoperative analgesia after corrective surgery of paediatric craniosynostosis is crucial in term of short and long-term outcomes.
- Trial name
- NCT04133467
- Testing
- scalp block
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Knee Osteoarthritis
Effect of Antigravity Treadmill in Knee Osteoarthritis (AGTreadmill)
To date, the anti-gravity treadmill, as a representative method of lower body positive pressure treadmills, has been rarely reported for knee osteoarthritis rehabilitation.
- Trial name
- AGTreadmill (NCT06347692)
- Testing
- antigravity treadmill, physical therapy exercise program
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Prince Sattam Bin Abdulaziz University
Pain, Knee Osteoarthritis
A Study to Evaluate the Efficacy and Safety of CG5503 Prolonged Release (PR) in Subjects With Moderate to Severe Chronic Pain Due to Osteoarthritis of the Knee
The purpose of this study is to evaluate whether tapentadol (CG5503) prolonged-release (PR) tablets at doses of 100-250 mg twice daily provide a better pain relief in patients with moderate to severe chronic pain due to…
- Trial name
- NCT00486811
- Testing
- Tapentadol ER (100 to 250 mg twice daily), Oxycodone CR (20 to 50 mg twice daily)
- Where
- 100 sites in Austria, Croatia and 11 more
- Volunteers
- 990 people
- Sponsor
- Grünenthal GmbH
Football Players
Effects of Windlass Versus Calcaneal Taping in Football Player With Plantar Fasciitis.
Plantar fasciitis is a prevalent ailment that affects the plantar fascia, a dense tissue strip that spans the underside of the foot, from the heel bone to the toes.
- Trial name
- NCT06637592
- Testing
- Calcaneal taping, Windlass taping
- Where
- 2 sites in Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Osteoarthritis of the Knee
A Study to Evaluate the Efficacy and Safety of X0002 Spray in Subjects With Osteoarthritis
This is a phase 2, multicenter, randomized, double blind (with dose), placebo controlled, parallel group, proof of concept, and dose range finding study to evaluate the efficacy, safety, and PK of X0002 spray in adult subjects…
- Trial name
- NCT02067611
- Testing
- X0002
- Where
- 20 sites in United States
- Volunteers
- 216 people
- Sponsor
- Lina Xu
Back Pain, Fusion of Spine, Lumbar Region
The Comparison of Postoperative Pain After Lumbar Fusion Surgery in Intravenous Patient-controlled Analgesia Between Conventional Mode and Optimizing B.I Mode With 'PAINSTOP' Equipment
The postoperative pain of lumbar fusion surgery is very severe that it is necessary to use additional analgesics as well as a patient controlled analgesia (PCA).
- Conditions
- Back Pain, Fusion of Spine, Lumbar Region, Spinal Stenosis
- Trial name
- NCT03047044
- Testing
- Optimizing basal infusion (B.I), Conventional PCA mode
- Where
- South Korea
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Shoulder Pain, Hemiplegia
Investigation of the Effectiveness of Flossing in Hemiplegic Patients With Shoulder Pain
This study aims to contribute to clinical practice by investigating the effectiveness of flossband application on range of motion, functionality, pain and sleep quality in hemiplegic patients with shoulder pain.
- Trial name
- NCT07261007
- Testing
- control, flossing
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Uskudar University
Myofascial Temporomandibular Disorder, Bruxism, Sleep
Factors Affecting Patients With Myofascial Temporomandibular Disorders
The aim of the study was to assess and compare the relationship between jaw function, neck disability, sleep quality, fatigue, and headache in patients with myofascial Temporomandibular Disorder (TMD) with Sleep Bruxism (SB) and…
- Conditions
- Myofascial Temporomandibular Disorder, Bruxism, Sleep, Sleep Disturbance, Jaw Spasm
- Trial name
- NCT04842136
- Testing
- Scales and indexes
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Rheumatic Heart Disease, Rheumatic Heart Disease in Children
Clinical Trial Phase I/IIa to Evaluate the Safety and Immunogenicity of StreptInCor
This is a Phase I/IIa, randomized, double-blind, placebo-controlled, dose-escalation clinical trial to test the candidate vaccine StreptInCor.
- Conditions
- Rheumatic Heart Disease, Rheumatic Heart Disease in Children, Vaccine Adverse Reaction, Rheumatic Diseases
- Trial name
- StreptInCorVac (NCT07078357)
- Testing
- StrepIncor
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Rheumatoid Arthritis
Filgotinib Alone and in Combination With Methotrexate (MTX) in Adults With Moderately to Severely Active Rheumatoid Arthritis Who Are Naive to MTX Therapy
The primary objective of this study is to evaluate the effects of filgotinib in combination with methotrexate (MTX) versus MTX alone in adults with active rheumatoid arthritis (RA).
- Trial name
- FINCH 3 (NCT02886728)
- Testing
- Filgotinib, MTX
- Where
- 186 sites in United States, Argentina and 29 more
- Volunteers
- 1,252 people
- Sponsor
- Gilead Sciences
Patellofemoral Pain Syndrome
Effect of Lower Back Treatment in People With Patellofemoral Pain Syndrome.
The purpose of this study is to determine if a lower back treatment would change the knee pain intensity and the level of functional activities as well as the muscle activities in people with anterior knee pain.
- Trial name
- NCT01975311
- Testing
- Lumbopelvic Manipulation, Passive lumbar spine flexion and extension
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Texas Woman's University
Myofascial Pain, Myofascial Trigger Point Pain
Investigating the Minimum Number of Needling Required to Optimize Trigger Point Injections Outcome
Myofascial pain is a common condition in which patients may experience severe chronic pain. The source of this pain is typically the soft tissue.
- Trial name
- NCT04732507
- Testing
- 1% plain lidocaine and 0.25% plain bupivacaine
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Arizona
Fibromyalgia
Combined Effects of Progressive Relaxation Exercises and Aquatic Therapy in Fibromyalgia.
Fibromyalgia, a chronic pain disorder, presents a significant challenge in healthcare due to its widespread musculoskeletal pain, tenderness, and a spectrum of associated symptoms.
- Trial name
- NCT06460636
- Testing
- progressive muscle relaxation therapy, aquatic therapy
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Hemiplegia, Shoulder Pain
Dry Needling Treatment in Hemiplegic Shoulder Pain
To evaluate the efficacy of dry needling therapy on shoulder pain and upper extremity functions in hemiplegic patients.
- Conditions
- Hemiplegia, Shoulder Pain, Myofascial Pain
- Trial name
- NCT04790071
- Testing
- Conventional physical therapy, Conventional physical therapy plus dry needling
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Kars State Hospital
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