Clinical trials: Musculoskeletal Symptom
Temporomandibular Joint and Muscle Disorder
An Implementation and Biobehavioral Study of Temporomandibular Joint and Muscle Disorder (TMJMD)
With the great economic costs and traditionally poor outcomes among chronic temporomandibular joint and muscle disorder (TMJMD) patients, it has become important to treat patients in the acute state, in order to prevent these…
- Trial name
- NCT00952900
- Testing
- Biobehavioral, Active Coping/Attention Intervention
- Where
- United States
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
Jaw Deformity, Facial Asymmetry
Computational Modeling for Prediction of Acoustic Changes in Vowel Production Due to Orthognathic Surgery
A computational model of human sound production based on high quality anatomic measurements and physical laws of sound propagation cannot be accomplished without a comprehensive data set including both 3D-images of the speaker's…
- Trial name
- PUMA (NCT01887977)
- Testing
- MRI examination
- Where
- Finland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Cerebral Palsy, Spasticity
Spinal Cord Stimulation for Children With Cerebral Palsy
The goal of this clinical trial is to help understand spinal cord excitability in children with cerebral palsy compared to neurologically typical children.
- Trial name
- NCT07516067
- Testing
- Transcutaneous Spinal Cord Stimulation (tSCS)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Martin Piazza
Neck Pain, Musculoskeletal Diseases
Exercise Intervention for Employees of the University of Bern
As part of a Swiss National Science Foundation SNSF project (On-site multi-component intervention to improve productivity and reduce the economic and personal burden of neck pain in Swiss Office-Workers, NEXpro = Neck EXercises…
- Conditions
- Neck Pain, Musculoskeletal Diseases, Occupational Health, Efficiency
- Trial name
- WeMoveVirtual (NCT05676528)
- Testing
- Exercise intervention
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Bern
Osteoporosis
Nitrates and Bone Turnover; Nitrates and Bone Turnover Bisphosphonate Sub-Study
Purpose: NABT: To compare five widely available nitrate formulations: (1) 15 of nitroglycerin (NTG) ointment, (2) 0.3 mg and (3) 0.6 mg of sublingual NTG, (4) 20 mg of isosorbide mononitrate (an oral tablet), and (5) 160 mg of…
- Trial name
- NABT;NABT-B (NCT01387672)
- Testing
- Nitrates (NABT Main trial)
- Where
- Canada
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Muscle Loss, Disuse Atrophy
Preventing Bed-rest Induced Muscle Loss in the Elderly
Episodes of inactivity due to hospitalisation, as short as 5 days, are associated with rapid muscle and strength loss in the elderly.
- Conditions
- Muscle Loss, Disuse Atrophy, Protein Metabolism, Prehabilitation
- Trial name
- NCT04422665
- Testing
- Resistance exercise
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Odontogenic Cysts, Keratocysts of the Jaw
Decompression of Odontogenic Cysts
The aim of this case-control study is to evaluate the effects of decompression of cystic jaw lesions by means of comparing pre- and post-decompression histologic findings.
- Conditions
- Odontogenic Cysts, Keratocysts of the Jaw, Cysts Dental, Pathology
- Trial name
- NCT06536907
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Spinal Stenosis Lumbar, Lumbar Disc Herniation
Cortical Bone Trajectory Screws vs. Traditional Pedicle Screws Fixation
Transforaminal lumbar interbody fusion (TLIF) had been favorable for effectively decrease pain and disability in specific spinal disorders; however, there has been concern regarding pedicle screw placement during TLIF surgery.
- Conditions
- Spinal Stenosis Lumbar, Lumbar Disc Herniation, Intervertebral Disc Degeneration
- Trial name
- NCT03105167
- Testing
- cortical bone trajectory screws, pedicle screws
- Where
- China
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Chronic Pain, Pain, Musculoskeletal
Physical Therapy Integrated With Mindfulness for Patients With Chronic Pain and Opioid Treatment
This study will use multiple methods to assess the feasibility of conducting a fully powered multisite clinical trial to test the effectiveness of integrating mindfulness-based interventions into physical therapy for patients…
- Conditions
- Chronic Pain, Pain, Musculoskeletal, Opioid Use, Physical Therapy
- Trial name
- PT-IN-MIND (NCT05875207)
- Testing
- Mindfulness based practice, Control/Standard Physical Therapy
- Where
- 2 sites in United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- University of Utah
De Quervain Syndrome
Mobilization With Movement Versus Soft Tissue Mobilization in Patients With De Quervain Tenosynovitis
this study will investigate the effects of mobilization with movement in addition to soft tissue mobilization on pain and range of motion in patients suffering from De Quervain Tenosynovitis.
- Trial name
- NCT05356624
- Testing
- Mulligan Mobilization, Soft Tissue Mobilization
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Stroke, Muscle Tone Abnormalities
Stroke and Assessment of Muscle Tone
Spasticity is defined as a state of increased muscle tone, which evokes an increased resistance to a passive and fast stretching of the muscle.
- Conditions
- Stroke, Muscle Tone Abnormalities, Pain, Muscle Spasticity
- Trial name
- NCT03814460
- Testing
- Assessment of Tone, Pain and Thickness
- Where
- 2 sites in Spain
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Seville
Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1
Baby Detect : Genomic Newborn Screening
Newborn screening (NBS) is a global initiative of systematic testing at birth to identify babies with pre-defined severe but treatable conditions.
- Conditions
- Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1, Phosphoglucomutase 1 Deficiency, Maturity Onset Diabetes of the Young
- Trial name
- BabyDetect (NCT05687474)
- Where
- Belgium
- Volunteers
- 6,824 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Liege
Diaphragm Injury, Muscle Weakness
Electromyography for Diaphragm Effort
Mechanical ventilation may be necessary to save the life of a patient due to an accident, pneumonia or surgery. The ventilator then temporarily takes over the function of the respiratory muscles.
- Conditions
- Diaphragm Injury, Muscle Weakness, Weaning Failure, Physiological Stress
- Trial name
- Edi2Pdi (NCT03580720)
- Testing
- Inspiratory threshold loading protocol
- Where
- Netherlands
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Statin-related Muscle Pain, Muscle Aches
7 Tesla MRI Study in Patients With Statin Related Muscle Complaints
Roughly 5-10% of statin-treated patients report muscle pain, aches, weakness, cramps, stiffness, or "heaviness" - typically occurring symmetrically in the legs.
- Conditions
- Statin-related Muscle Pain, Muscle Aches, Muscle Weakness, Muscle Cramp
- Trial name
- NCT04575090
- Testing
- Simvastatin
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Low Back Pain
The Efficacy of A Smartphone Application in Treating Non-Specific Low Back Pain
Evaluating the efficacy of a newly developed self-monitored mobile application in reducing office workers low back pain.
- Trial name
- NCT03994458
- Testing
- Smartphone Full version application, Samartphone limited version application
- Where
- Jordan
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Chronic Pain, Chronic Pain Syndrome
Outcomes Mandate National Integration With Cannabis as Medicine
This will be a multistate, multicenter clinical study to determine the efficacy and safety of medical cannabis for a wide variety of chronic medical conditions.
- Conditions
- Chronic Pain, Chronic Pain Syndrome, Chronic Pain Due to Injury, Chronic Pain Due to Trauma
- Trial name
- OMNI-Can (NCT03944447)
- Testing
- Cannabis, Medical, RYAH-Medtech Inhaler
- Where
- 17 sites in United States
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- OMNI Medical Services, LLC
Pain
MuscleCare™ Pain Relief Therapy vs. Voltaren® in the Relief of Trapezius Trigger Point Musculoskeletal Pain.
To determine the difference in efficacy of an all natural topical analgesic (MuscleCare) to a product containing the non-steroidal anti-inflammatory drug diclofenac (Voltaren) on trapezius trigger point pain.
- Trial name
- NCT03939884
- Testing
- MuscleCare Topical Product, Voltaren Topical, Nivea, Topical Cream
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Musculoskeletal Diseases or Conditions, Musculoskeletal Pain
Stress and Musculoskeletal Health in Employees
This study aims to evaluate potential correlation of stress as estimated by certain biological markers, namely saliva cortisol, Heart rate variability (HRV), Electromyography (EMG) with musculoskeletal system health status, and…
- Conditions
- Musculoskeletal Diseases or Conditions, Musculoskeletal Pain, Musculoskeletal Health, Stress
- Trial name
- MUStress (NCT06488547)
- Testing
- Diaphragmatic breathing (DF), Progressive Muscle Relaxation (PMR)
- Where
- 2 sites in Greece
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Covid19
Musculoskeletal Pain in Patients With Covid-19 Who Have Hospital Care
Worldwide, the COVID-19 pandemic continues to grow. Although COVID-19 mainly affects the lungs and internal organs, musculoskeletal injury from this disease was reported with the presentation of marked elevation in creatine…
- Trial name
- Covid19-Pain (NCT04632355)
- Testing
- Interview
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Pain, Opiate
Intensive Cryotherapy in the Emergency Department for Acute Musculoskeletal Injuries
Acute musculoskeletal (MSK) injuries, including strains, sprains or contusions, are a common reason patients seek emergency care. Pain control is an essential component of treatment.
- Conditions
- Pain, Opiate, Emergency
- Trial name
- NCT02720315
- Testing
- Intensive cryotherapy
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Stanford University
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