Clinical trials: Musculoskeletal Symptom
Knee Osteoarthritis
Ambulatory Continuous Adductor Canal Block to Facilitate Same Day Discharge Following Total Knee Arthroplasty: A Pilot Study
Patients scheduled to undergo total knee arthroplasty will receive motor sparing knee blocks with continuous adductor canal block along with multimodal analgesia started pre-operatively and continued into the postoperative…
- Trial name
- NCT02228759
- Testing
- Adductor canal block
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Mental Health Issue, Musculoskeletal Pain
CLIMB: Climbers' Longitudinal Attitudes to Injuries, Mental Health and Body Image
Eating disorders (ED) are serious mental illnesses with high mortality rates and significant impact on an individual's quality of life.
- Conditions
- Mental Health Issue, Musculoskeletal Pain, Eating Disorders, Relative Energy Deficiency in Sport
- Trial name
- NCT05587270
- Testing
- Web based surveys, DXA
- Where
- Sweden
- Volunteers
- 366 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Spinal Cord Injuries, Spasticity, Muscle
Transcutaneous Spinal Stimulation for Lower Limb Spasticity in Spinal Cord Injury
Spasticity develops months after spinal cord injury (SCI) and persists over time. It presents as a mixture of tonic features, namely increased muscle tone (hypertonia) and phasic features, such as hyperactive reflexes…
- Trial name
- NCT05457205
- Testing
- Electrical neuromodulation
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- University of Mississippi Medical Center
Hip Osteoarthritis, Knee Osteoarthritis
Fit-Joints: Getting Fit for Hip or Knee Replacement
Osteoarthritis leads to reduced independence and quality of life. Total hip replacement is a successful and cost-effective surgical intervention to relieve pain and improve functioning in patients with osteoarthritis.
- Trial name
- Fit-Joints (NCT02885337)
- Testing
- Multi-Modal Frailty Intervention, Usual Care
- Where
- 2 sites in Canada
- Volunteers
- 41 people
- Sponsor
- McMaster University
Myelopathy Cervical, Kyphosis Post Surgical
Comparison Between C3-6 Laminoplasty and C3 Laminectomy With Cervical Laminoplasty
Investigators performed a prospective randomized controlled trial for comparing postoperative clinical and radiological outcomes between C3 laminectomy with laminoplasty and C3-6 laminoplasty.
- Conditions
- Myelopathy Cervical, Kyphosis Post Surgical, Neck Pain, Ossification of Posterior Longitudinal Ligament
- Trial name
- NCT05006495
- Testing
- C3 laminectomy, C3 laminoplasty
- Where
- South Korea
- Volunteers
- 126 people
- Sponsor
- Seoul National University Hospital
Chronic Kidney Disease, End Stage Renal Disease
Klotho Gene Polymorphism in Dialyzed Patients With Hyperphosphatemia
Patients with chronic kidney disease (CKD) and those with end-stage renal disease (ESRD) undergoing renal replacement therapies show elevated serum phosphate levels which predispose them to cardiovascular calcifications and high…
- Conditions
- Chronic Kidney Disease, End Stage Renal Disease, Hyperphosphatemia, Renal Osteodystrophy
- Trial name
- NCT00374712
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Musculoskeletal Pain
Students' Lifestyle Behaviour and Later Health Care Utilization Due to Musculoskeletal Pain
This study aims to assess whether there is an association between students' lifestyle behaviour, in terms of physical activity level, sleep duration, smoking status, alcohol consumption and use of cannabis and other illegal…
- Trial name
- NCT06157112
- Testing
- Lifestyle behaviour (exposure in a observational study)
- Where
- Norway
- Volunteers
- 50,054 people, healthy volunteers welcome
- Sponsor
- Oslo Metropolitan University
Thymidine Kinase 2 Deficiency
An Open-Label Study of Continuation Treatment With Combination Pyrimidine Nucleosides in Patients With TK2 Deficiency
This is a Phase 2 prospective open-label treatment study of the safety and efficacy of doxecitine and doxribtimine in study participants with thymidine kinase 2 (TK2) deficiency who participated in the retrospective study…
- Trial name
- Continuation (NCT03845712)
- Testing
- doxecitine and doxribtimine
- Where
- 8 sites in United States, Israel and 1 more
- Volunteers
- 47 people
- Sponsor
- UCB BIOSCIENCES, Inc.
Musculoskeletal Inflammation, Exercise-Induced Muscle Damage
A Clinical Trial to Evaluate the Effects of Peptide Gummies on Markers of Inflammation, Physical Performance, and Recovery
This study will evaluate the effects of Parlay Recover peptide gummies (containing Body Protection Compound BPC-157) on markers of inflammation, physical performance, and recovery in physically active adults.
- Conditions
- Musculoskeletal Inflammation, Exercise-Induced Muscle Damage, Post-Exercise Recovery, Musculoskeletal Pain
- Trial name
- NCT07752381
- Testing
- Parlay Recover Peptide Gummies
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Parlay Wellness
Lower Back Pain
A Study to Evaluate Two Formulations of Carisoprodol in Subjects With Musculoskeletal Spasm of the Lower Back
The purpose of this study is to determine if two sustained released formulations of carisoprodol are more effective than placebo.
- Trial name
- NCT00671502
- Testing
- Carisoprodol SR
- Where
- 68 sites in United States
- Volunteers
- 840 people
- Sponsor
- Meda Pharmaceuticals
Adhesive Capsulitis
Effects of Scapular Mobilization on Shoulder Proprioception and Pain in Patients With Adhesive Capsulitis
Adhesive capsulitis is a common musculoskeletal condition. Painful gradual loss of both active and passive gleno-humeral motion resulting from progressive fibrosis and ultimate contracture of the gleno-humeral joint…
- Trial name
- NCT06387537
- Testing
- Conventional physical therapy, Scapular mobilization.
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Foundation University Islamabad
Shoulder Pain, Rotator Cuff Tendinitis
Effects of Externally Focused Shoulder Stabilization Exercises on Individuals With Rotator Cuff Tendinopathy
This study aims to evaluate the effectiveness of externally focused shoulder stabilization exercises on range of motion, pain, handgrip strength, and proprioception in patients with rotator cuff tendinopathy.
- Trial name
- NCT06702319
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Izmir Democracy University
Lumbar Herniated Disc
Evaluation of Minimally Invasive Microdiscectomy Versus Conventional Open Microdiscectomy For Lumbar Herniated Disc
Overall Objective: To evaluate pain and functional status of patients undergoing surgical correction for lumbar herniated disc, pre- and post-surgery, using subjective (VAS, Oswestry, PSQI, Patient Expectation), as well as…
- Trial name
- NCT00927056
- Testing
- Microdiscectomy
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Manitoba
Type 2 Diabetes, Neuropathy, Painful
Methylglyoxal Evaluation in Humans
The investigators will test the hypothesis that patients with low back pain associated with lumbar disc aberrancy will have elevated MGO-protein levels circulating in the blood that are comparable to patients with painful…
- Conditions
- Type 2 Diabetes, Neuropathy, Painful, Chronic Low-back Pain, Lumbar Disc Herniation
- Trial name
- MEH (NCT05350553)
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Osteo Arthritis Knee, Osteoarthritis
MRgFUS in the Treatment of Osteoarthritic Knee Pain
A double-blind placebo-controlled randomized clinical trial to evaluate the efficacy of magnetic resonance-guided focused ultrasound surgery (MRgFUS) in the treatment of pain caused by knee osteoarthritis (OA)
- Conditions
- Osteo Arthritis Knee, Osteoarthritis, Osteoarthritis, Knee
- Trial name
- NCT03453372
- Testing
- MRgFUS Treatment
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Istituto Ortopedico Rizzoli
TMJ Pain
Arthrocentesis Followed by Prolotherapy
we will do tmj joint lavage and followed by dextrose injection
- Trial name
- NCT04212975
- Testing
- joint lavage with dextrose
- Volunteers
- 60 people
- Sponsor
- Cairo University
Osteoporosis, Osteopenia
Does Treatment of Hypovitaminosis D Increase Calcium Absorption?
The purpose is to perform a one-year study designed to assess whether treatment of hypovitaminosis D increases intestinal absorption of calcium, subsequent retention of calcium within bone, decreases bone turnover, and favorably…
- Conditions
- Osteoporosis, Osteopenia, Vitamin D Deficiency, Hypoparathyroidism
- Trial name
- NCT00581828
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Neuralgia, Osteoarthritis of the Knee
Nerve Burial for Preventing Neuralgia After Total Knee Arthroplasty
This is a randomized study investigating whether identification, ligation, and burial of superficial branches of the saphenous nerve crossing the surgical field during total knee arthroplasty reduces the rate of post-operative…
- Trial name
- NCT02885467
- Testing
- Total knee arthroplasty with Saphenous nerve burial, Standard total knee arthroplasty
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Medstar Health Research Institute
Musculoskeletal Diseases, Depression
Physical Activity Levels and Musculoskeletal Health Among Health Science Academicians at Istanbul Aydin University
This study aims to investigate the relationship between physical activity levels and posture, sleep quality, depression, and musculoskeletal system problems among academic staff working in the health sciences field at Istanbul…
- Conditions
- Musculoskeletal Diseases, Depression, Sleep Wake Disorders, Posture
- Trial name
- PA-ACAD-IAU (NCT07445100)
- Testing
- Observational Data Collection
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Arthralgia
Evaluation of the Frequency of Occurrence of Joint Pain With Bevacizumab in Patients With Ovarian, Colorectal or Bronchopulmonary Cancer
Self-administered questionnaire survey to determine the presence or absence of joint pain during bevacizumab treatment for lung, ovarian, colorectal cancers.
- Trial name
- BEVARTHRALGIA2 (NCT03455907)
- Where
- 2 sites in France
- Volunteers
- 71 people
- Sponsor
- University Hospital, Lille
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