Clinical trials: Musculoskeletal Symptoms
Chronic Fatigue Syndrome
Cytokine Inhibition in Chronic Fatigue Syndrome Patients
Rationale: Chronic fatigue syndrome (CFS) is a medically unexplained syndrome for which no somatic or pharmacological treatment has been proven effective.
- Trial name
- CiCFS (NCT02108210)
- Testing
- Anakinra
- Where
- Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Healthy
Capsaicin-induced Muscle Pain in Humans
There is currently no specific diagnostic test for primary muscular pain. The present study investigates whether selective blockade of the suprascapular nerve can effectively abolish experimental pain arising from the…
- Trial name
- NCT02377180
- Testing
- Intramuscular capsaicin injection, Suprascapular nerve block, Local anesthetic infiltration
- Where
- Switzerland
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Osteoporosis, Sarcopenia
Effectiveness of Creatine Supplementation and Exercise on Muscle and Bone
As we age, we experience a reduction in muscle and bone which inevitably decreases strength and the ability to perform tasks of daily living such as gardening, carrying groceries, and climbing stairs.
- Trial name
- NCT01057680
- Testing
- creatine monohydrate
- Where
- 2 sites in Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Radiculopathy, Herniated Disk
Percutaneous Diskectomy SpineJet x Open Microdiskectomy in Treatment of Lumbar Radiculopathy
Approximately 300,000 patients undergo open surgical procedures to treat symptoms caused by disc herniation. Among the various surgical techniques practiced the percutaneous discectomy occupies its space since the first…
- Trial name
- PDOP_TLR (NCT01367860)
- Testing
- Open microdiscectomy, Percutaneous Diskectomy SpineJet
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Recovery Strategies After Simulated 400-meter Sprint in University Athletes
Effect of Combined Active Recovery and Foam Rolling Enhance Lactate Clearance and Reduce Muscle Soreness Following a Simulated Running Competition
This study investigates the effects of combining Active Recovery (AR) and Foam Rolling (FR) on blood lactate, heart rate, and muscle soreness in competitive 400-meter sprint athletes.
- Trial name
- ARFR (NCT07439523)
- Testing
- Active Recovery + Foam Rolling, Active Recovery Only
- Where
- Indonesia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Surabaya State University
Musculoskeletal Degeneration, Inflammation
Effects of Allopurinol on Inflammation and Ultrasonographic Changes in People With Elevated Uric Acid But no Symptoms
Hyperuricemia is a metabolic alteration defined as the presence of serum urate levels higher than 7 mg/dL. This has proven to be the maximum limit of solubility of urate in serum, any higher concentration leads to precipitation…
- Conditions
- Musculoskeletal Degeneration, Inflammation, Hyperuricemia
- Trial name
- NCT04012294
- Testing
- Allopurinol Pill
- Where
- 2 sites in Mexico
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Cardiologia Ignacio Chavez
Gout, Chronic Kidney Diseases
Anakinra vs. Steroids for the Treatment of Gout Attacks in Patients With Renal Disease (ASGARD): A Feasibility Study
The aim of this study is to determine the feasibility of running a phase III double-blind, double-dummy randomised controlled trial comparing Depo-Medrone 120mg intramuscular injection vs.
- Trial name
- ASGARD (NCT02578394)
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Mid and South Essex NHS Foundation Trust
Shoulder Pain, Shoulder Injuries
Electromyographic Analysis of Scapular Muscles During Closed Kinetic Chain Exercises
In shoulder rehabilitation, the inclusion of kinetic chain exercises is advocated in order to provide the necessary energy transfer to produce optimal force with minimal energy consumption.
- Conditions
- Shoulder Pain, Shoulder Injuries, Activation, Patient
- Trial name
- NCT06274827
- Testing
- Superficial Electromyography
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Work-Related Musculoskeletal Disorders, Musculoskeletal Disorders
Workstation Ergonomics Program at Al-Baha University
This study evaluates a workstation ergonomics program at Al-Baha University aimed at reducing work-related musculoskeletal symptoms among university employees who use computers regularly.
- Conditions
- Work-Related Musculoskeletal Disorders, Musculoskeletal Disorders, Occupational Musculoskeletal Disorders
- Trial name
- ERG-ABU (NCT07382466)
- Testing
- Workstation Ergonomics Program, Usual Practice (Control)
- Where
- Saudi Arabia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Al-Baha University
Shoulder Pain
Mobile Application Utilization for Measurement of Scapular Position
The purpose of this study is to determine the ability of a mobile clinical application to reliably and accurately track scapular motion in people with asymptomatic and symptomatic shoulders.
- Trial name
- MnMotion (NCT02773654)
- Testing
- Healthy Volunteers, Symptomatic Volunteers
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Cerebral Palsy, Spasticity
Power Wheelchair Joystick Use in Spastic Cerebral Palsy
There are over 750,000 individuals in the U.S. with Cerebral Palsy (CP). Up to 46% of adults with CP report limited mobility in their communities.
- Trial name
- NCT00337688
- Testing
- isometric joystick
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Shoulder Pain, Manual Therapy
Physiotherapist Approach to Shoulder's Diseases, Differences Between Fascial Manipulation and Standard Exercises
The study purpose is to compare the effects of Fascial Manipulation added to standard exercises protocol versus the simple exercises protocol.
- Trial name
- NCT03041727
- Testing
- Fascial Manipulation, Standard exercises protocol
- Where
- Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Bolognini di Seriate Bergamo
Back Pain, Low Back Pain
Low Back and Neck Pain in Nursing Students at The University of The West Indies
The purpose of this study is to identify the prevalence of neck and low back pain in nursing students enrolled at the University of the West Indies, Mona; to assess their knowledge, attitude and practice of good spine health and…
- Conditions
- Back Pain, Low Back Pain, Musculoskeletal Pain, Neck Pain
- Trial name
- NCT07167888
- Testing
- Clinical Control Group (Group A), Spine Exercise Program (Group B)
- Where
- Jamaica
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- The University of The West Indies
Chronic Pain, Musculoskeletal Pain
Online Pain Education in Addition to Usual Care in Chronic Pain.
The lack of pain specialists limits users' access to non-pharmacological therapeutic pain control strategies. In this context, digital health programs can reduce the inequity of access to interventions, contribute to the…
- Trial name
- NCT05302180
- Testing
- Pain neuroscience education, Usual care
- Where
- Brazil
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Universidade Cidade de Sao Paulo
Osteoarthritis, Traumatic Arthritis
Prospective Multicenter Post Approval Study of the LPS-Flex Mobile Bearing Knee
The purpose of the study is to assess the long-term performance of the NexGen LPS-Flex Mobile Bearing Knee in the treatment of patients with severe knee pain or degenerative knee disease.
- Conditions
- Osteoarthritis, Traumatic Arthritis, Avascular Necrosis of the Femoral Condyle, Moderate Varus
- Trial name
- NCT00854295
- Testing
- NexGen LPS-Flex Mobile Bearing Knee
- Where
- 3 sites in United States
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- Zimmer Biomet
Anesthesia, Pain, Postoperative
Ultrasound Guided Repositioning of a New Suture-Method Catheter for Adductor Canal Block
This is a randomized clinical trial in healthy volunteers. 12 volunteers will have suture-method catheters placed in the adductor canal of each leg using the long-axis plane and short-axis plane technique.
- Conditions
- Anesthesia, Pain, Postoperative, Pain, Pain, Joint
- Trial name
- NCT03315481
- Testing
- SAX catheter insertion, LAX catheter insertion
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Nordsjaellands Hospital
Musculoskeletal Pain
Students' Lifestyle Behaviour and Later Health Care Utilization Due to Musculoskeletal Pain
This study aims to assess whether there is an association between students' lifestyle behaviour, in terms of physical activity level, sleep duration, smoking status, alcohol consumption and use of cannabis and other illegal…
- Trial name
- NCT06157112
- Testing
- Lifestyle behaviour (exposure in a observational study)
- Where
- Norway
- Volunteers
- 50,054 people, healthy volunteers welcome
- Sponsor
- Oslo Metropolitan University
Neck Pain, Range of Motion
Comparative Effect of Neck Isometrics and Deep Cervical Flexion Exercises on Neck Pain Among Breastfeeding Females.
Neck pain is a common complaint among breastfeeding females, potentially attributed to sustained postures and muscle imbalance. Breastfeeding females experiencing neck pain, aged between 18-40 years, will be recruited through…
- Conditions
- Neck Pain, Range of Motion, Muscle Weakness, Breastfeeding
- Trial name
- NCT06877728
- Testing
- Neck isometric exercises: 3 times weekly for 6 consecutive weeks (18 sessions)
- Where
- Pakistan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Muscle Weakness
Mitochondria and Muscle Health in Elderly
The aim of this study is to characterize the relation between skeletal muscle mitochondrial metabolism and muscle health in elderly, physically compromised humans.
- Trial name
- ELMIH (NCT03666013)
- Where
- Netherlands
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Maastricht University
Subacromial Impingement Syndrome
Effects of Exercise Trainings on Pain, Function and AHD in Patients With SPS
Abnormal reduction of the AHD has been considered as one of the possible mechanisms in the aetiology of subacromial pain syndrome.
- Trial name
- NCT03494192
- Testing
- Scapula Retraction Exercise Group, Scapula Retraction +Glenohumeral Rotational Exercise Group
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
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