Clinical trials: Musculoskeletal System
Flat Feet, Flexible Flatfoot
Effect of Insole Added to Exercise in Patients With Bilateral Flexible Flatfoot
Pesplanus, commonly known as 'flatfoot,' is a common pathomechanical condition characterized by a lowered medial longitudinal arch (MLA) and exaggerated pronation.
- Conditions
- Flat Feet, Flexible Flatfoot, Balance; Distorted, Muscle Weakness
- Trial name
- NCT05056298
- Testing
- Custom made insole, Strengthening exercises of extrinsic foot muscles, Strengthening exercises of intrinsic foot muscles
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Horus University
Enthesopathy
Comparation of Ultrasonic Imaging of Enthesopathy in Patients With Psoriatic Arthritis and Psoriasis
Psoriatic arthritis(PsA) and psoriasis(Ps) are two systemic inflammatory diseases linked with rash of psoriasis, but there's still great controversy regarding the exact relationship between them.
- Trial name
- NCT02962271
- Testing
- Musculoskeletal Ultrasound
- Where
- China
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Knee Injuries, Knee Osteoarthritis
Walking Gait Biomechanics Following Knee Joint Effusion
The purpose of this study is to determine the sensitivity of a wearable sensor to detect changes in knee joint loading using an experimental knee joint effusion as a model for a common clinical physiological alteration in joint…
- Trial name
- NCT03805464
- Testing
- Knee Joint Effusion
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Duke University
Cervical Spondylosis
The Effect of Kinesio Taping With Cervical Spondylosis
The investigators aimed to evaluate the effect of kinesio tape application on the sense of proprioception in patients with cervical spondylosis.This research aims to determine the relationship between the sense of cervical…
- Trial name
- NCT05313763
- Testing
- conventional physical therapy, Active Kinesiotaping
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Osteoarthritis, Knee
MRI Markers of Cartilage Damage in Knee With Osteoarthritis
The objectives of this study are: to identify and develop techniques to minimize precision errors in magnetic resonance imaging (MRI) evaluation of knee cartilage, and to determine if results from newly-identified MRI techniques…
- Trial name
- NCT00820430
- Testing
- Magnetic Resonance Imaging
- Where
- 5 sites in United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- American College of Radiology
Osteoarthritis
Efficacy and Safety of Cortex Eucommiae (CE: Eucommia Ulmoides Oliver Extract) in Subjects With Mild Osteoarthritis
The purpose of this clinical trial is to evaluate the efficacy and safety of Cortex Eucommiae (CE: Eucommia ulmoides Oliver extract) in subjects with mild osteoarthritis (OA).
- Trial name
- NCT03744611
- Testing
- CE
- Where
- 3 sites in South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Jaseng Medical Foundation
Osteoporosis
HDDO-1614 Intervention Trial
Randomized, Open-label, Single-dose, 3-period, 6-sequence, 3-way crossover Study
- Trial name
- NCT03234244
- Testing
- Bazedoxifene 20 mg, Cholecalciferol, Bazedoxifene 20mg and Cholecalciferol
- Where
- South Korea
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Hyundai Pharmaceutical Co., LTD.
Osteoporosis
Study to Evaluate and Compare the Bioequivalence of Two Abaloparatide-sMTS Treatments in Healthy Women.
A study to evaluate the bioequivalence of abaloparatide between 2 abaloparatide-sMTS treatments 300 μg treatments applied to the thigh for 5 minutes.
- Trial name
- NCT04936984
- Testing
- abaloparatide-sMTS (Patheon), abaloparatide-sMTS (Kindeva)
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Radius Health, Inc.
Temporomandibular Disorders (TMD)
Acupuncture for Painful Temporomandibular Disorder
Temporomandibular disorder (TMD) is a common musculoskeletal pain condition affecting the jaw, and acupuncture is often used for treatment, though its neurological mechanisms are unclear.
- Trial name
- NCT06738667
- Testing
- Acupuncture
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Beijing Hospital of Traditional Chinese Medicine
Aging, Musculoskeletal Diseases
Effects of a Very Low Carbohydrate Ketogenic Diet or Mediterranean Diet on Markers of Musculoskeletal Health in Older Adults
Preclinical data indicate that very low carbohydrate ketogenic diets (KD) may prevent progression of age-related sarcopenia (skeletal muscle decline) but also may disturb bone metabolism.
- Trial name
- NCT06203392
- Testing
- Very low carbohydrate ketogenic diet, Mediterranean diet
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Florida
Muscle Soreness
Investigating the Effects of Different Soft Tissue Mobilizations on Delayed Onset Muscle Soreness
Delayed onset muscle soreness (DOMS) is associated with the initiation of a new physical activity or a sudden increase in exercise volume and intensity.
- Trial name
- NCT04248764
- Testing
- Foam roller application, Massage application
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Puncture, Surgical Gloves
The Effect of Using Double Gloves on Perforation in Orthopedic Surgery
Aim: This study aimed to investigate the effect of using double gloves on perforation in orthopedic surgery. Materials and Method: The randomized controlled experimental study was conducted between 30.11.2021 and 31.03.2022 in…
- Conditions
- Puncture, Surgical Gloves, Orthopedic Disorder
- Trial name
- NCT05928663
- Testing
- double surgical gloves, single surgical gloves
- Where
- Turkey (Türkiye)
- Volunteers
- 1,170 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
Rheumatoid Arthritis
Investigate the Safety, Tolerability and Pharmacokinetics of FBL-MTX
This is a prospective, single-center, randomized, double-blind, placebo-controlled, single-ascending dose (SAD) phase 1 study to evaluate the safety, tolerability and pharmacokinetics of FBL-MTX in healthy male and female…
- Trial name
- FolSmart (NCT05117593)
- Testing
- FBL-MTX
- Where
- Portugal
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- SOLFARCOS - Pharmaceutical and Cosmetic Solutions Ltd
Pain, Postoperative, Lumbar Disc Herniation
Su Jok Application in After Lumbar Disc Surgery
Surgical treatment is applied in 15% of individuals diagnosed with lumbar disc herniation. In this study, it was aimed to determine the effect of Su Jok application, which is one of the non-drug methods, in reducing or completely…
- Conditions
- Pain, Postoperative, Lumbar Disc Herniation, Surgery, Nurse's Role
- Trial name
- NCT05711706
- Testing
- Su Jok Application
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Niran Çoban
Effusion Joint
Ultrasound Guided Versus Landmark Guided Small & Medium Joint Arthrocentesis
Arthrocentesis is the removal of synovial fluid for analysis of pathologic processes. Small \& medium joint arthrocentesis will be defined as the following joints: elbow, wrist, finger, ankle and toe.
- Trial name
- NCT03327584
- Testing
- Arthrocentesis
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Temple University
Tooth Loss, Edentulous Jaw
Molecular Content of Peri-implant Sulcus During Wound Healing and Osseointegration Following Drilling and Piezosurgery
This study aims to evaluate the levels of cytokines, chemokines and growth factors in peri-implant sulcular fluid (PISF) during healing and osseointegration at osteotomy sites prepared either with piezosurgery (PS) or drills (D).
- Trial name
- NCT03538184
- Testing
- Piezosurgery, Drill
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Ege University
Bruxism, Temporomandibular Joint Disorders
Aspects Associated With Obstructive Sleep Apnea, Bruxism and Orofacial Pain
This study evaluated the influence of the sleep bruxism (SB), awake bruxism (AB) and obstructive sleep apnea syndrome (OSAS) on the signs and symptoms of temporomandibular disorders (TMD).
- Conditions
- Bruxism, Temporomandibular Joint Disorders, Obstructive Sleep Apnea Syndrome
- Trial name
- NCT03766464
- Testing
- Evaluation of TMD and pain sensitivity, Evaluation of SB, Evaluation of AB
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Bone Loss
Artificial Intelligence-Enhanced Three-Dimensional Reconstruction of Ridge Deficiencies
n the current study, AI-assisted 3D ridge augmentation of combined vertical and horizontal deficient ridges utilizing allogenic dentin block versus allogenic dentin shell graft will be assessed.
- Trial name
- NCT06693921
- Testing
- AI/guided block graft, AI/guided shell graft
- Where
- 2 sites in Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Leg Cramps, Nocturnal, Poor Sleep Quality
Weighted Blanket in Pregnancy
Pregnancy is frequently accompanied by sleep disturbances, musculoskeletal discomfort, anxiety, and stress, which may negatively affect maternal well-being and daily functioning.
- Conditions
- Leg Cramps, Nocturnal, Poor Sleep Quality, Pregnancy, Anxiety
- Trial name
- Weighted (NCT07309016)
- Testing
- Weighted Blanket
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Jaw, Edentulous
Study of Neodent Implantable Devices of GM Zygomatic Line
GM Zygomatic implant is intended to be surgically placed in the posterior region of the maxilla and zygoma. It is indicated for multiple prostheses in case of severe resorption in the maxilla and total edentulism (situations in…
- Trial name
- NCT04328116
- Testing
- Dental Implants
- Where
- Brazil
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Neodent
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