Clinical trials: Mycobacterium Avium Complex
Intubated Patients, Percutaneous Tracheostomy
C-MAC Videolaryngoscopy Versus Direct Laryngoscopy for Percutaneous Tracheostomy
When preparing an ICU patient for percutaneous dilational tracheostomy, correct positioning of the endotracheal tube is important. During the procedure, it is possible to puncture the cuff.
- Trial name
- VIDLARTRAQ (NCT05416489)
- Testing
- C-MAC videolayngoscopy technique, Laryngoscopy technique
- Where
- 2 sites in Spain
- Volunteers
- 90 people
- Sponsor
- Hospital Clinico Universitario de Santiago
Mycobacterium Avium-Intracellulare Infection, HIV Infections
A Study of Viracept in AIDS Patients With Mycobacterium Avium Complex Disease (MAC)
The purpose of this study is to see if it is safe and effective to give Viracept to AIDS patients who are being treated for MAC.
- Trial name
- NCT00002170
- Testing
- Nelfinavir mesylate
- Where
- 5 sites in United States
- Sponsor
- Agouron Pharmaceuticals
Mycobacterium Avium Complex, Non-tuberculous Mycobacterium Pulmonary Disease
Safety, Tolerability, Pharmacokinetics and Efficacy of SPR720 for the Treatment of Patients With Mycobacterium Avium Complex (MAC) Pulmonary Disease
To evaluate the pharmacokinetics (PK) of SPR719, the active moiety, generated from the orally (po) administered SPR720 prodrug in a patient population with nontuberculous mycobacteria pulmonary disease (NTM-PD)
- Trial name
- NCT04553406
- Testing
- SPR720, Open-label Standard of Care
- Where
- 9 sites in United States
- Volunteers
- 2 people
- Sponsor
- Spero Therapeutics
Nontuberculous Mycobacterial Lung Disease, Nontuberculous Mycobacterium Infection
Hypertonic Saline for MAC
The MAC-HS study is a testing whether hypertonic saline helps improve symptoms and clearance of mycobacteria in patients with M. avium complex lung infections.
- Trial name
- NCT04921943
- Testing
- Hypertonic saline, Azithromycin, Ethambutol
- Where
- 3 sites in United States, Canada
- Volunteers
- 50 people
- Sponsor
- Oregon Health and Science University
Mycobacterium Avium-intracellulare Infection, HIV Infections
A Phase II Safety and Efficacy Study of Clarithromycin in the Treatment of Disseminated M. Avium Complex (MAC) Infections in Patients With AIDS
This study is designed to evaluate the efficacy and safety of clarithromycin given orally at 1 of 3 doses to treat disseminated Mycobacterium avium complex infections (MAC) in patients with AIDS.
- Trial name
- NCT00000644
- Testing
- Clarithromycin
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Videolaryngoscopy, Double Lumen Tube
Comparison Of Videolaryngoscopes In Double Lumen Tube
Along with the technological advances in medicine, videolaryngoscope is the most commonly preferred technique for intubation with double lumen tube.
- Conditions
- Videolaryngoscopy, Double Lumen Tube, One-lung Ventilation
- Trial name
- D&Xblade (NCT03826706)
- Testing
- C-MAC Videolaryngoscope D blade, McGrath MAC Videolaryngoscope X3 blade
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Inonu University
Pulmonary MAC, Energy Metabolism
Energy Metabolism for the Patients With Pulmonary Mycobacterium Avium Complex
We aim to examine energy metabolism in patients with pulmonary MAC and clarify the causes of emaciation. We will also investigate the following: the relation between energy metabolism and degree of pulmonary MAC progression…
- Conditions
- Pulmonary MAC, Energy Metabolism, Emaciation
- Trial name
- NCT03550820
- Where
- Japan
- Volunteers
- 105 people
- Sponsor
- National Hospital Organization Minami Kyoto Hospital
HIV Test and Treat
Study to Evaluate the Feasibility of Community-based Test and Treat Strategies Among Men Who Have Sex With Men and Transgender Women to Increase the Uptake of HIV Testing and Treatment Services in Thailand
HIV counseling and testing, risk reduction counseling, provision of condoms and lubricants Same-day result HIV testing along with pre-test and post-test counseling, including risk reduction counseling, will be provided according…
- Trial name
- NCT02383602
- Where
- Thailand
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Thai Red Cross AIDS Research Centre
Thoracic
Macintosh Versus GlideScope Versus C-MAC for Double Lumen Endotracheal Intubation
The double lumen endotracheal tube (DLT) is the most widely-used device for single lung ventilation in current thoracic anesthesia practice.
- Trial name
- NCT05091281
- Testing
- Intubation of the double lumen tube by Macintoch laryngoscope, Intubation of the double lumen tube by Glidescope videolaryngoscope, Intubation of the double lumen tube by C-MAC®(D) videolaryngoscope
- Where
- Egypt
- Volunteers
- 105 people
- Sponsor
- Tanta University
HIV Infections
Study of How Indinavir (an Anti-HIV Drug) and Rifabutin (a Drug Used to Treat MAC, an HIV-Associated Disease) Interact in HIV-Positive and HIV-Negative Adults
The purpose of this study is to evaluate the safety of giving indinavir and rifabutin at the same time (simultaneously) vs 4 hours apart (staggered) to HIV-positive and HIV-negative adults.
- Trial name
- NCT00000877
- Testing
- Indinavir sulfate, Rifabutin
- Where
- 8 sites in United States
- Volunteers
- 31 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Nontuberculous Mycobacteria, Mycobacterium Avium Complex
Clarithromycin for the Treatment of Infections Caused by Nontuberculous Mycobacteria (NTM)
Use of oral clarithromycin for treatment of chronic lung disease due to Mycobacterium avium-intracellulare and other non-tuberculous Mycobacteria
- Trial name
- NCT00600769
- Testing
- Clarithromycin
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- The University of Texas Health Science Center at Tyler
Intubation Complication
Evaluation of Hemodynamic Response to Laryngoscopy and Endotracheal Intubation Using Conventional Laryngoscope Versus C-MAC Video Laryngoscope in Patients Undergoing Elective Coronary Artery Bypass Grafting (CABG) Surgery
This study is being done to compare hemodynamic response upon endotracheal intubation using either conventional laryngoscopy with Macintosh blade versus C-Mac video laryngoscope in patients undergoing elective coronary artery…
- Trial name
- NCT04433884
- Testing
- Endotracheal intubation using a laryngoscope
- Where
- Pakistan
- Volunteers
- 86 people
- Sponsor
- Aga Khan University
Attention Control, Healthy Volunteers
Attentional Control
The project is dedicated to understanding the integration within the brain of signals of different natures that contribute to attentional control.
- Trial name
- MACBRAIN (NCT03872999)
- Testing
- Functional brain imaging without any contrast agent
- Where
- France
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Mycobacterium Avium Complex
Clofazimine in the Treatment of Pulmonary Mycobacterium Avium Complex (MAC)
The purpose of this study is to evaluate the clinical effectiveness and safety of clofazimine when used to treat Mycobacteria avium complex (MAC) lung disease. Funding Source - FDA OOPD
- Trial name
- NCT02968212
- Testing
- Clofazimine, sugar pill
- Where
- 6 sites in United States
- Volunteers
- 102 people
- Sponsor
- Oregon Health and Science University
Mycobacterium Avium-intracellulare Infection, HIV Infections
The Safety and Effectiveness of Clarithromycin Plus Zidovudine or Dideoxyinosine in the Treatment of Mycobacterium Avium Complex (MAC) Infections in Children With AIDS
To evaluate three doses of clarithromycin in children with AIDS and Mycobacterium avium complex (MAC) infection who are receiving concurrent antiretroviral therapy.
- Trial name
- NCT00000971
- Testing
- Clarithromycin, Zidovudine, Didanosine
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Abbott
Nasal Intubation
Nasal Intubation Using King Vision Video Laryngoscopy
This study was designed to determine the comparison between the King Vision video laryngoscope 、 McGrath MAC video laryngoscope and Macintosh laryngoscope for nasotracheal intubation.Patients were divided into 3 groups of 30…
- Trial name
- NCT03126344
- Testing
- King Vision video laryngoscope, McGrath MAC video laryngoscope, Macintosh laryngoscope
- Where
- China
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Intubation; Difficult, Cervical Spine Injury
Head Motion in Pediatric Patients Endotracheally Intubated With Video Laryngoscopy Versus Direct Laryngoscopy
The purpose of this study is to evaluate if intubation with video laryngoscopy (VL) will result in less head motion and therefore less cervical motion when compared with direct laryngoscopy (DL).
- Trial name
- NCT02405390
- Testing
- Video Laryngoscopy, Direct Laryngoscopy, Storz C-Mac® laryngoscope
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Nicklaus Children's Hospital f/k/a Miami Children's Hospital
Mitral Annular Calcification, Mitral Valve Disease
MitrAl Valve Calcium aSsEssmEnt With TrueVue Trans-illumination 3D Rendering.
The study of calcifications involving the mitral valve is extremely important for the planning of both surgical and percutaneous procedures.
- Trial name
- MAC-SEE (NCT07612553)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Centro Cardiologico Monzino
Cardiac Arrest, Intubation, Endotracheal
Pediatric Endotracheal Intubation
We hypothesized that the McGrath MAC EMS is beneficial for intubation of pediatric manikins while performing CPR. In the current study, we compared effectiveness of the McGrath MAC EMS and MIL laryngoscopes in child resuscitation…
- Trial name
- EMS (NCT02291653)
- Testing
- McGrath, MIL
- Where
- Poland
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- International Institute of Rescue Research and Education
Hypoxemia, Obstructive Sleep Apnea
The Prediction Model of Hypoxemia for Safe Bronchoscopy
The purpose of this study is to develop the hypoxemia prediction model during fiberoptic bronchoscopy under MAC(monitored anesthesia care) anesthesia.
- Trial name
- NCT01370993
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Seoul National University Bundang Hospital