Clinical trials: Mycobacterium Avium Complex
Memory Disorders, Neurocognitive Disorders
Creation of an Ecological Tool Assessing Episodic Memory in Geriatrics
In this study the participants can be recruited via scheduled consultation and external institutions (associations, senior club..).
- Trial name
- ECOTESTGER (NCT05668598)
- Testing
- ecological MAI test
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Lens
Pediatric, Cardiopulmonary
Pediatric Endotracheal Intubation During Resuscitation
Endotracheal intubation (ETI) is perceived as the optimal method of providing and maintaining a clear and secure airway. The 2010 European Resuscitation Council (ERC) guidelines emphasized the importance of minimal interruption…
- Trial name
- PETI (NCT02286297)
- Testing
- McGRATH® MAC, AirTraq, GlideScope
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- International Institute of Rescue Research and Education
Hoarseness of Voice, Sore-throat
A Prospective,Randomised, Open Label Study for Comparison of the Incidence and Severity of Postoperative Sore Throat (POST) Using C-MAC Video Laryngoscope and Traditional Macintosh Laryngoscope for Intubation
The aim of this study is to compare the incidence of postoperative sore throat after intubation with two different types of laryngoscopes.
- Trial name
- NCT05531617
- Testing
- Intubation
- Where
- India
- Volunteers
- 54 people
- Sponsor
- Seth Gordhandas Sunderdas Medical College
MAC Lung Disease, Treatment Refractory MAC Lung Disease
Study of Epetraborole in Patients With Treatment-refractory MAC Lung Disease
This is a pivotal Phase 2/3, double-blind, placebo-controlled study of epetraborole + OBR (Optimized Background Regimen) versus placebo + OBR in patients with treatment-refractory MAC lung disease.
- Trial name
- NCT05327803
- Testing
- Epetraborole
- Where
- 91 sites in United States, Australia and 2 more
- Volunteers
- 177 people
- Sponsor
- AN2 Therapeutics, Inc
Requiring Sedation by Sevoflurane in ICU, Adult Patients
Evaluation of Richmond Agitation Sedation Scale According to Alveolar Concentration of Sevoflurane During a Sedation With Sevoflurane in ICU Patients
Describe the Richmond Agitation Sedation Scale (RASS) values corresponding to the values of Minimum alveolar concentration of sevoflurane during sedation of patients in ICU
- Conditions
- Requiring Sedation by Sevoflurane in ICU, Adult Patients, Patients Covered by French Health Care System, Patients Who Have Given Their Consent
- Trial name
- SEVORASS (NCT02202720)
- Testing
- Sevoflurane
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Clermont-Ferrand
Anesthesia
Comparison of Effect of Equi-MAC Anesthetics on PSI
The aim of this study is to compare the patient state index values produced by equi-MAC of sevoflurane and desflurane in patients undergoing single-agent volatile anesthesia.
- Trial name
- NCT03587779
- Testing
- Sevoflurane, Desflurane
- Where
- South Korea
- Volunteers
- 74 people
- Sponsor
- Kangbuk Samsung Hospital
MAC Lung Disease, Treatment Refractory MAC Lung Disease
ICoN-1 Phase 3 Study of the Efficacy and Safety of Treatment With MNKD-101, Clofazimine Inhalation Suspension
This clinical trial is designed to compare the efficacy and safety of Clofazimine Inhalation Suspension versus placebo when added to guideline-based therapy (GBT)
- Conditions
- MAC Lung Disease, Treatment Refractory MAC Lung Disease, Mycobacterium Infections, Nontuberculous
- Trial name
- ICoN-1 (NCT06418711)
- Testing
- Clofazimine Inhalation Suspension
- Where
- 99 sites in United States, Australia and 3 more
- Volunteers
- 132 people
- Sponsor
- Mannkind Corporation
Nontuberculous Mycobacterial Lung Disease, Mycobacterium Avium Complex
Hypertonic Saline Inhalation for Mycobacterium Avium Complex Pulmonary Disease
The SALINE trial will investigate the effect of Hypertonic Saline inhalation plus best supportive care on burden of symptoms, clearance of mycobacteria and functional capacities in participants with Mycobacterium avium complex…
- Trial name
- SALINE (NCT05192057)
- Testing
- Hypertonic Saline inhalation
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Radboud University Medical Center
Mycobacterium Avium-Intracellulare Infection, HIV Infections
Evaluation of the Therapeutic Benefit of r-metHuIFN- Gamma in AIDS Patients With Disseminated Mycobacterium Avium-Intracellulare (MAI) Infection: A Multi-Centered Pilot Study
To examine the effectiveness of subcutaneous gamma interferon in reducing severity of Mycobacterium avium- intracellulare (MAI) bacillemia episodes in AIDS patients in an open-label dose-randomized multi-center pilot clinical…
- Trial name
- NCT00002037
- Testing
- Trifluridine
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Amgen
Intubation, Videolaryngoscopy
A Comparison of C-MAC Videolaryngoscopy and Direct Laryngoscopy for Nasotracheal Intubation
Nasotracheal intubation is indicated in patients undergoing oral, maxillofacial, or dental procedures. During nasal intubation with the traditional Macintosh laryngoscope, use of Magill's forceps or external laryngeal…
- Conditions
- Intubation, Videolaryngoscopy, Children
- Trial name
- NCT03908775
- Testing
- C-MAC videolaryngoscope, Direct Laryngoscope
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Inonu University
Obesity
Comparison of McCoy Laryngoscope and C-MAC D-blade Video Laryngoscope in Obese Patients
Obesity is associated with difficult intubation rate of 30%, and this study was performed to compare the use of McCoy laryngoscope and C-MAC D-blade video laryngoscope for intubation in obese patients.
- Trial name
- NCT05146531
- Testing
- McCoy laryngoscope, C-MAC D-blade video laryngoscope
- Where
- South Korea
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Eun Young Park
Anxiety, Depression
Managing Anxiety From Cancer (MAC): Testing an Intervention for Anxiety in Older Adults With Cancer and Their Caregivers
This study is being done to test the effects of Managing Anxiety from Cancer (MAC) therapy on anxiety compared to usual care, in patients and their caregivers.
- Conditions
- Anxiety, Depression, Quality of Life
- Trial name
- NCT03168971
- Testing
- Managing Anxiety from Cancer (MAC)
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Mycobacterium Avium-Intracellulare Infection, HIV Infections
A Study of Rifabutin, Used Alone or With Ethambutol in the Prevention of Mycobacterium Avium Complex (MAC) Bacteremia in Patients With AIDS
To optimize Mycobacterium avium Complex (MAC) prophylaxis in AIDS patients by measuring serum rifabutin levels and adjusting the dose accordingly.
- Trial name
- NCT00002343
- Testing
- Ethambutol hydrochloride, Rifabutin
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Pharmacia
Thyroidectomy
The Effect of Preoperative Anxiety Level on the Induction Dose of Propofol and Minimum Alveolar Concentration (MAC) Hour of Sevoflurane During Thyroidectomy
This study is to evaluate the level of anxiety, and to check the correlation of induction dose and the amount of sevoflurane to keep anesthetic depth in in female patients undergoing thyroidectomy.
- Trial name
- NCT01149239
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Yonsei University
Colorectal Cancer, Gut Microbiota
Modified MAC Diet and Gut Microbiota in CRC Patients
To explore the changes in the composition and diversity of intestinal microbiota during 3-weeks of modified MAC diet and conventional diet in stage I or low-risk stage II colorectal cancer (CRC) patients after surgery.
- Conditions
- Colorectal Cancer, Gut Microbiota, Diet Intervention
- Trial name
- NCT05039060
- Testing
- Modified MAC diet (3-weeks)
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Korea University Anam Hospital
Endobronchial Intubation, Double Lumen Tube Intubation
Hyperangulated vs Standard Videolaryngoscopy vs Direct Laryngoscopy for Double-Lumen Endobronchial Tube Intubation
This is a prospective, randomized, single-center, three-arm, open-label, low-risk medical device clinical study conducted at the Department of Anesthesiology and Reanimation, Trakya University Medical Faculty.
- Conditions
- Endobronchial Intubation, Double Lumen Tube Intubation, Thoracic Surgery, One Lung Ventillation (OLV)
- Trial name
- NCT07614529
- Testing
- C-MAC Hyperangulated D-Blade Videolaryngoscopy, C-MAC Macintosh Blade Videolaryngoscopy, Direct Macintosh Laryngoscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Trakya University
Coloboma, Anophthalmia
Pathogenesis and Genetics of Microphthalmia, Anophthalmia and Uveal Coloboma (MAC)
Background: Uveal coloboma is a condition where the eye does not form normally. It occurs early in the fetus s development during pregnancy. It can lead to different kinds of eye problems, including blindness.
- Conditions
- Coloboma, Anophthalmia, Microphthalmia
- Trial name
- NCT01778543
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- National Eye Institute (NEI)
Airway Management
Self-Assembled Modified Macintosh Videolaryngoscope Versus McGrath Macintosh (MAC®) Videolaryngoscope: Which is Better?
Videolaryngoscopy highly improves success rate for endotracheal intubation in both normal and difficult airway. However, commercially available videolaryngoscope such as McGrath MAC® can be costly. The.
- Trial name
- NCT04850976
- Testing
- Endotracheal intubation
- Where
- Indonesia
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Lung Infection
Safety and Efficacy of Inhaled Interferon Gamma-1b in Pulmonary MAC Infection
The purpose of this research study is to test the safety and effectiveness of inhaled Interferon gamma-1b (IFN-g 1b), when administered for 48 weeks and in combination with oral antibiotics which may be administered for up to 72…
- Trial name
- NCT00043355
- Testing
- interferon gamma-1b
- Volunteers
- 100 people
- Sponsor
- InterMune
Objective Vocal Cord Movement Assessment by C-Mac Videolaryngoscope Vs Airway Ultrasound in Ca Thyroid
Comparison of Two Technique for Assessment of Vocal Cord Movement by C-Mac Videolaryngoscope vs Airway Ultrasound.
This study is planned to compare C-Mac video-laryngoscope and airway ultrasound as two novel techniques (causing least discomfort to the patients) for the detection of impaired vocal-cord movement after thyroid surgery.
- Trial name
- NCT02847780
- Testing
- Active Comparator :C-Mac Videolaryngoscope, Experimental: Airway ultrasound,
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Rajiv Gandhi Cancer Institute & Research Center, India