Clinical trials: Mycobacterium Avium Complex
Mycobacterium Avium-Intracellulare Infection, HIV Infections
Placebo-Controlled Trial of Safety and Efficacy of Thalidomide in Patients With Infections Due to Mycobacterium and/or HIV
To demonstrate, in patients with tubercular or nontubercular mycobacterium infections with or without HIV infection, the safety of thalidomide use as judged by symptoms, physical exam, and studies of microbiologic, immunologic…
- Conditions
- Mycobacterium Avium-Intracellulare Infection, HIV Infections, Tuberculosis, Mycobacterium Infection
- Trial name
- NCT00002104
- Testing
- Thalidomide
- Where
- 2 sites in United States
- Sponsor
- Aaron Diamond AIDS Research Center
Mycobacterium Infections, Nontuberculous
Validation of Patient Reported Outcome Measures in Participants With Nontuberculous Mycobacterial Lung Infection Caused by Mycobacterium Avium Complex
The primary objective of this study is to generate evidence demonstrating the domain specification (via modern psychometric methods), reliability, validity, and responsiveness (within-subject meaningful change) of the…
- Trial name
- ARISE (NCT04677543)
- Testing
- ALIS, Azithromycin, Ethambutol
- Where
- 62 sites in United States, Argentina and 10 more
- Volunteers
- 99 people
- Sponsor
- Insmed Incorporated
Mycobacterium Infections, Nontuberculous
Study to Evaluate ALIS (Amikacin Liposome Inhalation Suspension) in Participants With Nontuberculous Mycobacterial Lung Infection Caused by Mycobacterium Avium Complex
The main objective of this study is to evaluate the efficacy of ALIS (amikacin liposome inhalation suspension) + background regimen (azithromycin [AZI] + ethambutol [ETH]) compared to the ELC (empty liposome control) + background…
- Trial name
- ENCORE (NCT04677569)
- Testing
- ALIS, Azithromycin, Ethambutol
- Where
- 258 sites in United States, Argentina and 21 more
- Volunteers
- 425 people
- Sponsor
- Insmed Incorporated
Endotracheal intübation
Glottic Opening Percentage (POGO) With Miller and McGrath MAC Videoingoscopes
The aim of this study is to compare the percentage of glottic opening (POGO) with Miller and McGrath MAC Videoingoscopes compared to the direct epiglottis lifting method.
- Trial name
- NCT05820542
- Testing
- miller laryngoscope, McGrath MAC videolaryngoscope
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Zonguldak Bulent Ecevit University
Difficult Intubation, Morbid Obesity
A Comparison of McGrath MAC Versus C-MAC Videolaryngoscopes in Morbidly Obese Patients
Along with the technological advances in medicine, videolaryngoscope is the most commonly preferred technique for intubation of expected difficult airway management such as morbidly obese patients.
- Conditions
- Difficult Intubation, Morbid Obesity, Videolaryngoscopy
- Trial name
- mcgrath&cmac (NCT03657927)
- Testing
- C-MAC videolaryngoscope, McGrath MAC videolaryngoscope
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Inonu University
Laparoscopic Cholecystectomy
Dexmedetomidine Reduces Sevoflurane MAC-BAR During Pneumoperitoneum
This clinical trial aims to learn the impact of dexmedetomidine on the minimum alveolar concentration blunting the adrenergic response (MAC-BAR) of sevoflurane to carbon dioxide pneumoperitoneum in patients undergoing…
- Trial name
- NCT06575179
- Testing
- Dexmedetomidine low-dose, normal Saline, Dexmedetomidine high-dose
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Fujian Provincial Hospital
Tuberculous Meningitis
Xpert MTB/RIF Assay for Diagnosis of Tuberculous Meningitis (TBM) in Maharaj Nakorn Chiang Mai Hospital
Early diagnosis and appropriate treatment of tuberculous meningitis (TBM) are crucial steps to reduce morbidity and mortality. The WHO recommended to use Xpert MTB/RIF assay to diagnose pulmonary TB, pediatrics TB, extra…
- Trial name
- NCT05781646
- Testing
- Xpert MTB/RIF
- Volunteers
- 62 people
- Sponsor
- Chiang Mai University
Assessment, Difficult Airway Intubation
Preoperative Assessment of Difficult Laryngoscopy Using Different Videolaryngoscopes
preoperative assessment of difficult airways are the subject of debate. Now, measuring the thyromental distance or evaluating the mallampati score, mandible protrusion or body mass index still not 100% specifically say anything.
- Conditions
- Assessment, Difficult Airway Intubation, Preoperative
- Trial name
- NCT03999866
- Testing
- airtraq, mcgrath mac x-blade, storz c-mac
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people
- Sponsor
- Kocaeli University
Autoimmune Liver Diseases, Immunological Mechanisms
The MAI-FOIE Cohort
The MAI-FOIE cohort will be a French multicenter cohort with the development of a biobank including patients with autoimmune, metabolic and medicated liver diseases
- Trial name
- NCT07594990
- Where
- 13 sites in France
- Volunteers
- 800 people
- Sponsor
- Nantes University Hospital
Anesthesia
Does McGRATH® MAC Videolaryngoscope Decrease the Number of People Required to Perform Intubation During Anesthesia ?
The main objective of this study is to compare the proportion of tracheal intubations for which more than one person is necessary when using the McGRATH® MAC videolaryngoscope.
- Trial name
- MGM3 (NCT02926144)
- Testing
- Laryngoscope with video, Laryngoscope without video
- Where
- 4 sites in France
- Volunteers
- 300 people
- Sponsor
- Hopital Foch
Tuberculosis, Non-tuberculous Mycobacterial Diseases (Including MAC Disease)
Safety And Efficacy Of Rifabutin In Patients For Non-HIV Patients
The objective of this surveillance is to collect information about 1) adverse drug reaction not expected from the LPD (unknown adverse drug reaction), 2) the incidence of adverse drug reactions in this surveillance, and 3)factors…
- Trial name
- NCT00810407
- Testing
- rifabutin
- Volunteers
- 628 people
- Sponsor
- Pfizer
Lumbar Spinal Stenosis
Study Comparing Local/ MAC Anesthesia in Lumbar Decompression
Explore efficacy, complications, and other factors associated with anaesthetic choice- To evaluate the efficacy of local + MAC as an alternative anesthetic to general anesthesia and to analyze patients' outcomes and experiences.
- Trial name
- NCT04992572
- Testing
- Propofol Injection, Lidocaine Hydrochloride, Injectable
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Stanford University
Anti-Bacterial Agents
Carbapenems De-escalation as Antimicrobial Stewardship
Early de-escalation of carbapenems can reduce unnecessary use of carbaepenems compared with late de-escalation without compromised clinical outcomes
- Trial name
- NCT03114358
- Testing
- Early Carbapenem de-escalation
- Volunteers
- 104 people
- Sponsor
- Chiang Mai University
Nontuberculous Mycobacterial Pulmonary Disease (NTM-PD)
A Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of SPR720 as Compared With Placebo for the Treatment of Participants With Mycobacterium Avium Complex (MAC) Pulmonary Disease
The purpose of the study is to evaluate 1. The microbiological response and clinical efficacy of SPR720 compared with placebo in participants with nontuberculous mycobacteria pulmonary disease (NTM-PD). 2.
- Trial name
- NCT05496374
- Testing
- SPR720 500 mg, SPR720 1000 mg
- Where
- 28 sites in United States
- Volunteers
- 25 people
- Sponsor
- Spero Therapeutics
HIV Infection, HIV-1 Infection
A Drug Interaction Study Investigating the Effect of Rifabutin on the Pharmacokinetics of Maraviroc
Healthy volunteers are being recruited for this pharmacokinetics study. The objective is to characterize the pharmacokinetic properties of maraviroc alone and when administered with rifabutin and to assess rifabutin and…
- Conditions
- HIV Infection, HIV-1 Infection, Mycobacterium Avium Complex (MAC)
- Trial name
- RIFAMARA (NCT01894776)
- Testing
- Rifabutin, Maraviroc
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Intubation, Airway
A Comparison of the C-mac and Bonfils Intubation Fibrescope
The study aims to determine the better device to facilitate intubation in patients with a limited neck movement and small mouth opening.
- Trial name
- NCT02210338
- Testing
- Karl Storz C-MAC, Bonfils Intubation Fibrescope
- Where
- Singapore
- Volunteers
- 64 people
- Sponsor
- Singapore General Hospital
Mycobacterium Avium-intracellular Infection, HIV Infections
The Safety and Effectiveness of Clarithromycin in the Prevention of Mycobacterium Avium Complex (MAC) Infection in HIV-Infected Patients
To determine whether clarithromycin is safe and effective in preventing disseminated Mycobacterium avium Complex in HIV-infected patients with CD4 counts <= 100 cells/mm3.
- Trial name
- NCT00002336
- Testing
- Clarithromycin
- Where
- 22 sites in United States
- Sponsor
- Abbott
Mycobacterium Avium Complex Pulmonary Disease
Prevention of Recurrence With Cordyceps Sinensis in Mycobacterium Avium Complex Pulmonary Disease
The goal of this clinical trial is to learn if cordyceps sinesis capsule (Bailiing Capsule) works to prevent the recurrence of microbiologically cured mycobacterium avium complex pulmonary disease in adults.
- Trial name
- NCT07174076
- Testing
- cordyceps sinesis capsule
- Where
- 6 sites in China
- Volunteers
- 300 people
- Sponsor
- Bin Cao
Intubation, Nociceptive Pain
NoL, HR and MABP Responses to Tracheal Intubation Performed With MAC Blade Versus Glidescope
Prospective, randomized and controlled who will be conducted in Maisonneuve-Rosemont hospital and whose objectives are: To observe if the alterations of the NoL index and the standard monitoring (Mean Arterial Blood Pressure and…
- Conditions
- Intubation, Nociceptive Pain, Anesthesia, Laryngoscopy
- Trial name
- NoLint (NCT03277872)
- Testing
- Laryngoscopy with GlideScope (GVL) Blade, Laryngoscopy with MacIntosh (MAC) Blade
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Critical Illness
C-MAC Videolaryngoscope for Insertion of a Transesophageal Echocardiography Probe in ICU Patients
Transesophageal echocardiography (TEE) is commonly used in operating room (cardiac surgery), as well as in other critical care settings.
- Trial name
- VIDLARECO (NCT04980976)
- Testing
- Blind insertion technique, C-MAC videolaryngoscope insertion technique
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Hospital Clinico Universitario de Santiago