Clinical trials: Mycobacterium Avium Complex
Orthopedic Disorders
The Different Analgesic Potency of Volatile Anesthetics at Equi-MAC
The aim of this clinical trial is to evaluate the difference of analgesic potency of sevoflurane and desflurane at equi-minimum alveolar concentration using a surgical pleth index.
- Trial name
- NCT02609802
- Testing
- Sevoflurane, Desflurane
- Where
- South Korea
- Volunteers
- 77 people
- Sponsor
- Kangbuk Samsung Hospital
Obesity
Comparative Effectiveness of Intubating Devices in the Morbidly Obese
This prospective, randomized study will compare the effectiveness of 4 different airway intubating devices which are most commonly used.
- Trial name
- NCT01114945
- Testing
- McGrath, GlideScope, Direct Macintosh Laryngoscopy
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- Cedars-Sinai Medical Center
Tracheal Intubation
McGrath Mac VideoLaryngoscope vs the Macintosh Laryngoscope
Videolaryngoscopes become widely used. The aim of this study is to compare McGrath Mac videolaryngoscope to conventional MacIntosh laryngoscope in patients without known risk of difficult of mask ventilation and of tracheal…
- Trial name
- MGM-Eval (NCT02292901)
- Testing
- Macintosh laryngoscope, McGrath Mac videolaryngoscope
- Where
- 2 sites in France
- Volunteers
- 158 people
- Sponsor
- Hopital Foch
Intubation
C-MAC Video Stylet vs. Video Endoscope
The purpose of the study is to compare first attempt success rates and time until intubation to establish the learning curves of the participating anaesthesiologists with two different intubation strategies: (Karl Storz C-MAC VS…
- Trial name
- NCT03749837
- Testing
- C- MAC VS, Video Endoscope
- Where
- 3 sites in Canada, Spain and 1 more
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Mycobacterium Avium Complex Pulmonary Disease
A Prospective, Multicenter, Single-arm MAC-PD Cohort: a NTM-NET and ESGMYC Collaborative Study
To gain insight in the effectiveness of, adherence and adjustments to guideline-based three-drug antimycobacterial therapy in patients with Mycobacterium avium complex pulmonary disease (MAC-PD) during the first 6 months of…
- Trial name
- MAC-PD cohort (NCT05906316)
- Where
- 11 sites in United States, Belgium and 8 more
- Volunteers
- 100 people
- Sponsor
- Radboud University Medical Center
Gynecologic Cancers, Breast Cancer
Virtual Mindful After Cancer (MAC) Intervention to Promote Sexual Health for Breast and Gynecologic Cancer Survivors
The goal of this study is to plan for a large scale evaluation of a program called Mindful After Cancer, or MAC. The MAC Program provides training in mindfulness, educational material about sexual health after cancer, and support…
- Trial name
- MAC (NCT07055854)
- Testing
- Mindful After Cancer Program
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- Oregon State University
Mycobacterium Avium Complex, Mycobacterium Avium-Intracellulare Infection
Drug Exposure and Minimum Inhibitory Concentration in the Treatment of MAC Lung Disease
The incidence and prevalence of nontuberculous mycobacteria (NTM) infections have gradually increased over the years worldwide (1-3).
- Conditions
- Mycobacterium Avium Complex, Mycobacterium Avium-Intracellulare Infection, Gram-Positive Bacterial Infections, Mycobacterium Infections
- Trial name
- NCT05824988
- Testing
- Drug exposure
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
Morbid Obesity
Interaction Between Head/Neck Position and C-MAC Blade Geometry on Videolaryngoscopic Intubation in Morbidly Obese Patients: A Randomized Controlled Trial
This study aims to explore the effect of head/neck position (sniffing vs ramped) and C-MAC blade geometry (MAC vs D-blade) on intubation in morbidly obese patients. The patients will be randomized into 4 groups: 1.
- Trial name
- C-MAC (NCT07636746)
- Testing
- Sniffing position and using MAC blade., Ramped position and MAC Blade, videolaryngoscopy
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Ain Shams University
Unexpected Difficult Airway
Airway Management Study to Evaluate the C-MAC Video Laryngoscope as an Alternative to the Direct Laryngoscopy
The purpose of this study is to evaluate the C-MAC video laryngoscope in difficult airway situations.
- Trial name
- NCT01122433
- Testing
- Endotracheal intubation using the C-MAC video laryngoscope
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Johannes Gutenberg University Mainz
Non-Tuberculous Mycobacterial Pneumonia, Cystic Fibrosis
A Pilot Study to Assess the Effect of Intermittent iNO on the Treatment of NTM Lung Infection in CF and Non-CF Patients
The purpose of this open-label, multicenter, non-randomized, pilot study is to assess the safety of high dose intermittent iNO for treatment of NTM infection in CF and non-CF patients.
- Conditions
- Non-Tuberculous Mycobacterial Pneumonia, Cystic Fibrosis, Mycobacterial Pneumonia, Mycobacterium Abscessus Infection
- Trial name
- NCT04685720
- Testing
- LungFit
- Where
- Australia
- Volunteers
- 15 people
- Sponsor
- Beyond Air Inc.
Anesthesia
MAC Bipsectral Index Below 50 for Chronic Opioid User
The purpose of this study is to find difference in Minimum Alveolar Concentration(MAC) for maintaining Bispectral Index (BIS) below 50 between chronic opioid users and opioid naive patients.
- Trial name
- NCT02582437
- Testing
- History for opioid use
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Cancer Center, Korea
Mycobacterium Avium Complex, Nontuberculous Mycobacterium Infection
Comparison of Two- Versus Three-antibiotic Therapy for Pulmonary Mycobacterium Avium Complex Disease
NTM therapy consists of a multi-drug macrolide based regimen for 18-24 months. Treated patients frequently experience debilitating side effects, and many patients delay the start of antibiotic treatment due to these risks.
- Trial name
- MAC2v3 (NCT03672630)
- Testing
- Azithromycin, Ethambutol, Rifampin
- Where
- 26 sites in United States, Canada
- Volunteers
- 474 people
- Sponsor
- Kevin Winthrop
Mycobacterium Avium-Intracellulare Infection, HIV Infections
A Double-Blind Randomized Clinical Trial of a Rifabutin Regimen in the Treatment of Mycobacterium-Avium Complex (MAC) Bacteremia in Patients With AIDS
To determine if a drug regimen containing rifabutin will eradicate or decrease the numbers of Mycobacterium avium complex (MAC) organisms in blood, improve the symptoms associated with MAC infection, and increase survival in…
- Trial name
- NCT00001995
- Testing
- Rifabutin
- Where
- 22 sites in United States
- Volunteers
- 200 people
- Sponsor
- Pharmacia
Mycobacterium Avium-intracellulare Infection, HIV Infections
The Safety and Effectiveness of Clarithromycin and Rifabutin Used Alone or in Combination to Prevent Mycobacterium Avium Complex (MAC) or Disseminated MAC Disease in HIV-Infected Patients
To compare the efficacy and safety of clarithromycin alone versus rifabutin alone versus the two drugs in combination for the prevention or delay of Mycobacterium avium Complex (MAC) bacteremia or disseminated MAC disease.
- Trial name
- NCT00001030
- Testing
- Clarithromycin, Rifabutin
- Where
- 42 sites in United States, Tanzania
- Volunteers
- 1,100 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Mycobacterium Avium-intracellulare Infection, HIV Infections
A Comparison of Three Drug Combinations Containing Clarithromycin in the Treatment of Mycobacterium Avium Complex (MAC) Disease in Patients With AIDS
To compare the efficacy and safety of clarithromycin combined with rifabutin, ethambutol, or both in the treatment of disseminated Mycobacterium avium Complex (MAC) disease in persons with AIDS, including individuals who have or…
- Trial name
- NCT00001058
- Testing
- Indinavir sulfate, Ritonavir, Ethambutol hydrochloride
- Where
- 34 sites in United States, Tanzania
- Volunteers
- 246 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Hepatitis B
Immunologic Response of Hepatitis B Vaccine
This study aims to evaluate the immunologic response to the two hepatitis B virus (HBV) vaccination booster strategies in previously vaccinated HIV-infected adults at Maharaj Nakorn Chiang Mai Hospital.
- Trial name
- NCT03219203
- Testing
- Hepatitis B vaccine
- Where
- Thailand
- Volunteers
- 80 people
- Sponsor
- Chiang Mai University
Intubation; Difficult or Failed, Sore-throat
Intubation with Different Angled Intubation Tubes Using C-macr D Blade Videolaringoscope;
In this study we compared post-operative sore throat, ease and time of intubation, hoarseness, subglottic damage and hemodynamic changes to orotracheal intubation using three different intubation stylets with C-MAC R…
- Conditions
- Intubation; Difficult or Failed, Sore-throat, Hoarseness
- Trial name
- NCT06011967
- Testing
- Intubation using C-MAC D blade videolariyngoscope
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Consciousness, Level Depressed, Intraoperative Awareness
Awareness During Blended Anaesthesia
the aim of this study was to estimate the relations between Bispectral Index values and explicit or implicit memory or dreams during two different minimal alveolar concentration (MAC) of sevoflurane in patients undergoing blended…
- Trial name
- NCT01800578
- Testing
- monitor for depth of hypnosis
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- Germano De Cosmo
Nontuberculous Mycobacterial Infections
Effectiveness of Rifabutin in the Treatment of Mycobacterium Avium Complex
Treatment of adults with chronic Mycobacterium avium-intracellulare complex lung infections who have failed or are intolerant of rifampin.
- Trial name
- NCT03164291
- Testing
- Rifabutin
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- The University of Texas Health Science Center at Tyler
Classical Hodgkin Lymphoma
CD30 CAR T-cells Post AutoHSCT for Poor-risk Hodgkin Lymphoma
Patients with poor risk classical Hodgkin Lymphoma (cHL) will undergo myeloablative chemotherapy (MAC) with autologous stem cell transplantation (AutoHSCT) and subsequently receive autologous CD30+ CAR T-cells.
- Trial name
- NCT06617286
- Testing
- CD30 CAR T-cell
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- New York Medical College