Clinical trials: Myocardial Infarction
Cancer, Myocardial Infarction
NORVIT and WENBIT - Long-term Follow-up
Two large homocysteine-lowering B-vitamin intervention trials have been performed in Norway during the period 1998 to 2005, NORVIT and WENBIT.
- Conditions
- Cancer, Myocardial Infarction, Cerebrovascular Stroke
- Trial name
- NORVITWENBIT (NCT00671346)
- Where
- 2 sites in Norway
- Volunteers
- 6,839 people
- Sponsor
- Haukeland University Hospital
Myocardial Infarction
Which Therapy for Acute Heart Attacks? (The WEST Study)
In the setting of acute myocardial infarction (heart attacks), the principle objective of the WEST Study is to compare the impact on clinical outcomes of 3 different treatment strategies.
- Trial name
- NCT00121446
- Testing
- tenecteplase, enoxaparin, clopidogrel
- Where
- 16 sites in Canada
- Volunteers
- 300 people
- Sponsor
- University of Alberta
Non STEMI, Unstable Angina
Safety and Efficacy of CMX-2043 for Protection of the Heart and Kidneys in Subjects Undergoing Coronary Angiography
The objective of this study is to evaluate CMX-2043 for prevention of renal and cardiac injury associated with coronary angiography in patients with acute coronary syndrome (ACS), but excluding ST-elevation myocardial infarction…
- Trial name
- CARIN (NCT02103959)
- Testing
- CMX-2043
- Volunteers
- 361 people
- Sponsor
- Ischemix, LLC
Myocardial Infarction
Research on Infarction With Open Arteries Using OCT and CMR
The purpose of this study is to determine the prevalence of plaque disruption and to assess the composition of disrupted plaques in patients with myocardial infarction (MI) and non-obstructive coronary artery disease (CAD) using…
- Trial name
- RIO (NCT02270359)
- Testing
- OCT, CMR, contrast agent, Gadolinium
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- NYU Langone Health
Coronary Disease, Myocardial Infarction
Chronical Illness-related Limitations of the Ability to Cope With Rising Temperatures, Third Wave
The CLIMATE-III Observational Study examines to what extent chronically ill patients experience adverse health effects because of heat and whether the patients' specific health behavior, somatosensory amplification, risk and…
- Conditions
- Coronary Disease, Myocardial Infarction, Heart Failure, Arrhythmias, Cardiac
- Trial name
- CLIMATE-III (NCT06890208)
- Testing
- No intervention
- Where
- Germany
- Volunteers
- 176 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
STEMI, Acute Myocardial Infarction
Antiplatelets and Intramyocardial Hemorrhage in STEMI: Incidence and Outcomes
The MIRON-PLATELET study is a retrospective, observational multi-center analysis assessing the impact of different antiplatelet therapies on hemorrhagic myocardial infarction (HMI) incidence and outcomes in STEMI patients.
- Trial name
- MIRON-PLATELET (NCT06851325)
- Where
- United States
- Volunteers
- 6,180 people
- Sponsor
- Rohan Dharmakumar
Coronary Artery Disease
the Change of CEM and the Prognosis of Coronary Artery Disease in Real Clinical Practice
The purpose of this study is to investigate the change of total cholesterol content of erythrocyte membranes (CEM) in patients with coronary artery disease treated with secondary prevention drugs, and the correlation with the…
- Trial name
- CCEMPCAD (NCT03473860)
- Volunteers
- 200 people
- Sponsor
- Lu'an Municipal Hospital
Cardiogenic Shock, Malignant Arrhythmias
The Caribbean Registry of Extracorporeal Membrane Oxygenation (ECMO) From the University Hospital in Martinique
The project's main goal is to collect baseline clinical and procedural data as well as to assess clinical outcomes for all patients undergoing VV, VA or VAV ECMO implantation in the French West Indies and Guiana.
- Conditions
- Cardiogenic Shock, Malignant Arrhythmias, Ischemic or Valvular Heart Failure, Drepanocytosis and Thoracic Syndrome
- Trial name
- NCT07351435
- Volunteers
- 1,200 people
- Sponsor
- University of Genova
Acute ST Segment Elevation Myocardial Infarction
Performance of Bioresorbable Scaffold in Primary Percutaneous Intervention of ST Elevation Myocardial Infarct
Patients presenting with acute ST elevation myocardial infarct urgently need revascularization. Standard of care is establishing bloodflow through the coronary vessels using thrombus aspiration catheter, and securing the result…
- Trial name
- BVS in STEMI (NCT02067091)
- Testing
- stent implant in a coronary artery
- Where
- 2 sites in Denmark, Norway
- Volunteers
- 120 people
- Sponsor
- Haukeland University Hospital
Acute Heart Failure, Decompensated Heart Failure
Characterisation of phenotYpes in aCute Heart faiLure patiEnts
An observational cohort study to evaluate the benefit of functional parameters, radiomics and blood biomarkers to predict the outcome of patients with acute heart failure.
- Conditions
- Acute Heart Failure, Decompensated Heart Failure, Cardiogenic Shock
- Trial name
- CYCLE (NCT07508891)
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Circulatory Shock, Sepsis
Shock and Acute Conditions OutcOmes Platform
In-hospital mortality of patients admitted in the intensive care unit (ICU) for circulatory shock remains high (between 20 and 40%).
- Conditions
- Circulatory Shock, Sepsis, Cardiogenic Shock, Major Trauma
- Trial name
- ShockCO-OP (NCT06376318)
- Testing
- Inotrope, Mechanical circulatory support, anti-bodies
- Where
- Canada
- Volunteers
- 1,000 people
- Sponsor
- Saint-Louis Hospital, Paris, France
Chronic Total Occlusion of Coronary Artery
A Prospective, First in Man Study to Evaluate the Safety and Performance of the NovaCross™ Micro-catheter
This is a prospective, non-randomized, first-in-man investigational study, to assess the safety and technical feasibility, deployment and withdrawal characteristics of the NovaCross™ micro-catheter during an interventional…
- Trial name
- NCT01978860
- Testing
- NovaCross, CTO
- Where
- Israel
- Volunteers
- 2 people
- Sponsor
- Chanan Schneider
Ischemic Heart Disease (IHD), Myocardial Infarction (MI)
CMR Prognostic Markers in Ischemic Heart Disease
Ischemic heart disease (IHD) remains a leading cause of morbidity and mortality worldwide. Accurate risk stratification is essential for guiding clinical management and improving long-term outcomes in patients with ischemic…
- Trial name
- NCT07351825
- Testing
- Cardiac Magnetic Resonance Imaging
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Acute Myocardial Infarction
Everolimus Stent in Myocardial Infarction
Randomized trial to test the efficacy and safety of newer Drug Eluting Stent generation in patient with acute myocardial infarction treated with primary percutaneous coronary intervention (PCI)
- Trial name
- RaCES-MI (NCT01684982)
- Testing
- everolimus eluting stent, sirolimus eluting stent
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- San Giuseppe Moscati Hospital
Integrated Assessment, Immune-Inflammatory
Integrated Assessment of Immune-Inflammatory and Metabolic Biomarkers for Prediction of Coronary No-Reflow Following Primary PCI in STEMI Patients
This study aims to evaluate the combined predictive value of immune-inflammatory and metabolic biomarkers for coronary no-reflow following primary percutaneous coronary intervention (PCI) in patients with ST-segment elevation…
- Conditions
- Integrated Assessment, Immune-Inflammatory, Metabolic Biomarkers, Coronary No-Reflow
- Trial name
- NCT07890168
- Testing
- Assessment of immune-inflammatory and metabolic biomarkers
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Sohag University
Non-ST Segment Elevation Myocardial Infarction, Unstable Angina Pectoris
Intensive Statin Treatment in Chinese Coronary Artery Disease Patients Undergoing PCI
This randomized, open label, controlled, parallel group study is designed to test whether 2-day high dose atorvastatin administration before PCI and 30-day continuous intensive atorvastatin treatment is superior to usual care, in…
- Conditions
- Non-ST Segment Elevation Myocardial Infarction, Unstable Angina Pectoris, Stable Angina Pectoris
- Trial name
- ISCAP (NCT01293097)
- Testing
- Atorvastatin, Statin
- Where
- China
- Volunteers
- 2,884 people
- Sponsor
- Peking University First Hospital
Stable Angina, Unstable Angina
International Collaboration of Comprehensive Physiologic Assessment
The current study evaluated prognostic implication of comprehensive physiologic assessment using fractional flow reserve, coronary flow reserve (CFR) and index of microcirculatory resistance (IMR).
- Conditions
- Stable Angina, Unstable Angina, Non-ST Elevation Myocardial Infarction, ST-segment Elevation Myocardial Infarction
- Trial name
- NCT03690713
- Testing
- Fractional flow reserve, coronary flow reserve, and index of microcirculatory resistance
- Where
- 4 sites in Japan, South Korea and 1 more
- Volunteers
- 1,397 people
- Sponsor
- Seoul National University Hospital
Acute Myocardial Infarction
Hemorrhagic Myocardial Infarction Detection by Post-reperfusion Troponin Kinetics
Pilot trial to determine diagnostic efficacy of post-reperfusion troponin kinetics in detection of hemorrhagic myocardial infarction
- Trial name
- MIRON-TROP (NCT05872308)
- Where
- 2 sites in United States, India
- Volunteers
- 227 people
- Sponsor
- Rohan Dharmakumar
Acute Myocardial Infarction
Effects of Percutaneous Coronary Intervention in Patients With Cardiac Arrest After Acute Myocardial Infarction: a 2-Year Study
The purpose of this study is To assess percutaneous coronary intervention 's effect on short- and long- term outcomes, and complication incidence in resuscitated victims of cardiac arrest after acute myocardial infarction
- Trial name
- NCT02576691
- Testing
- percutaneous coronary intervention
- Volunteers
- 2,363 people
- Sponsor
- Yuanli Lei
Non-ST Elevation Myocardial Infarction, Acute Coronary Syndrome
Cardiac MRI Prior to Invasive Coronary Angiography in Patients With Suspected Non-ST-Elevation Myocardial Infarction
Patients with a suspected myocardial infarction are subdivided into ST-elevation and non-ST-elevation myocardial infarctions (STEMI and NSTEMI, respectively) using ECG.
- Trial name
- KaPSICA-CMR (NCT06566625)
- Testing
- Cardiac MRI (CMR) examination
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Region Stockholm