Clinical trials: Myocardial Ischemia
Atherosclerosis of Coronary Artery, Cardiovascular Disease
Radiation Dose From Computed Tomography Before and After Implementation of a High Pitch Dual Spiral Technique
The purpose of this study is to compare the radiation exposure of a variety of chest CT examinations performed on the current state of the art CT scanners (64 slice, dual source CT scanner) with the radiation exposure for…
- Conditions
- Atherosclerosis of Coronary Artery, Cardiovascular Disease, Pulmonary Embolism, Aortic Aneurysm Without Mention of Rupture Nos
- Trial name
- FLASH (NCT01111760)
- Where
- United States
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- Michael Gallagher
Acute Myocardial Infarction, Pulmonary Embolism
Retrospective Study of Acute Chest Pain in Extremely Critical Condition for More Than Ten Years
Acute non-traumatic chest pain is a common kind of symptom in extremely critical condition, with various pathogenesis and different level of risk . Chest pain in high risk takes 1/3 of that.
- Conditions
- Acute Myocardial Infarction, Pulmonary Embolism, Aortic Dissection
- Trial name
- RESPECT (NCT02837120)
- Where
- China
- Volunteers
- 7,000 people
- Sponsor
- Qilu Hospital of Shandong University
Acute ST-segment Elevation Myocardial Infarction
EARLY Routine Catheterization After Alteplase Fibrinolysis vs. PPCI in ST-Segment-Elevation MYOcardial Infarction
The EARLY-MYO (EARLY routine catheterization after alteplase fibrinolysis vs. primary PCI in acute ST-segment elevation MYOcardial infarction) is an investigator-initiated, prospective, multicenter, randomized (1:1), open-label…
- Trial name
- EARLY-MYO (NCT01930682)
- Testing
- Alteplase, Early post-fibrinolytic catheterisation, Primary PCI
- Where
- China
- Volunteers
- 344 people
- Sponsor
- RenJi Hospital
Chronic Kidney Disease, Stable Angina
Effect of Platelet Inhibition According to Clopidogrel Dose in Patients With Chronic Kidney Disease
Impaired renal function is associated with reduced responsiveness to clopidogrel. There are no studies which have shown a means by which to overcome platelet hyporesponsiveness in patients with chronic kidney disease (CKD).
- Trial name
- CKD (NCT01328470)
- Testing
- Clopidogrel, cilostazol
- Where
- South Korea
- Volunteers
- 85 people
- Sponsor
- Kyunghee University Medical Center
Cardiovascular Diseases, Heart Diseases
Gender Response To Coronary Risk
To examine sex differences in behavioral and psychosocial variables such as occupation, Type A behavior, and hostility as they related to primary coronary risk factors.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease
- Trial name
- NCT00005224
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
STEMI, Chest Pain
Microvascular Recovery With Ultrasound in Myocardial Infarction (MRUSMI) Post PCI Trial
The investigators propose to test the effectiveness of a technique that uses a modified commercially available ultrasound system used for cardiac imaging, and a commercially available ultrasound contrast agent (microbubbles) to…
- Trial name
- MRUSMI (NCT02170103)
- Testing
- percutaneous intervention (PCI), Microbubbles, Ultrasound
- Where
- 2 sites in Brazil, Netherlands
- Volunteers
- 50 people
- Sponsor
- University of Nebraska
Cardiogenic Shock, Renal Replacement Therapy
REnal reCOVery After ECMO for Cardiogenic Shock (RECOVECMO)
This retrospective study assesses long term renal outcome in patients having suffered medical or post cardiotomy refractory cardiogenic shock requiring renal replacement therapy (RRT) concomitant with veno-arterial extracorporeal…
- Conditions
- Cardiogenic Shock, Renal Replacement Therapy, Venoarterial Extracorporeal Membrane Oxygenation
- Trial name
- RECOVECMO (NCT05788211)
- Testing
- standard of care
- Where
- France
- Volunteers
- 93 people
- Sponsor
- University Hospital, Bordeaux
Epicardial Fat Tissue
Epicardial Fat Tissue and Severity of Coronary Artery Disease in Diabetic vs Non Diabetic Patients
correlation between EFT volume measured by Cardiac MRI and the angiographic severity of coronary artery disease (Syntax Score) in diabetic vs non diabetic CAD population and detect if there is a cut off value for each group that…
- Trial name
- NCT04111198
- Testing
- Cardiac MRI
- Volunteers
- 80 people
- Sponsor
- Bakeer Mohamed Bakeer
Delirium, Ischemic Stroke
CTSN Embolic Protection Trial
This is a prospective, multi-center, randomized effectiveness trial of the CardioGard Embolic Protection Cannula in high-risk valve surgery patients.
- Conditions
- Delirium, Ischemic Stroke, Acute Kidney Injury, Heart Valve Disease
- Trial name
- EMPRO (NCT06027788)
- Testing
- CardioGard Embolic Protection Cannula, Standard Aortic Cannula
- Where
- 24 sites in United States, Canada
- Volunteers
- 842 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Myocardial Infarction, Heart Attack
Home Telemonitoring In Patients After Myocardial Infarction
This study is being done to determine if taking an electrocardiogram (ECG) by a portable device (SmartHeart) followed by a phone call will improve patient outcomes by early recognition of abnormalities and decrease emergency room…
- Trial name
- NCT04664881
- Testing
- SmartHeart Device
- Where
- United States
- Volunteers
- 195 people
- Sponsor
- Mayo Clinic
Cardiogenic Shock, Mechanical Circulatory Support
OPTIMIZE 5.5 - Optimizing Impella 5.5 Outcomes Through Advanced Data Science
The main goal of this observational, study is to develop a clinical decision support tool utilizing Impella 5.5 pump parameters to predict native heart recovery and prevent adverse events, by leveraging data science and…
- Conditions
- Cardiogenic Shock, Mechanical Circulatory Support, Cardiogenic Shock Post Myocardial Infarction
- Trial name
- OPTIMIZE (NCT07619144)
- Testing
- Micro-axial flow pump support
- Where
- Austria
- Volunteers
- 100 people
- Sponsor
- Medical University of Vienna
Coronary Artery Disease
Duration of Platelet Inhibition by Aspirin
The well established importance of regular aspirin administration stands on firm grounds, as large meta-analyses have shown this therapy to significantly reduce the risk of death.
- Trial name
- NCT00671021
- Testing
- Platelet aggregation
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Coronary Stenosis, Stent Stenosis
Culotte Versus DK-CRUSH Technique in Non-left Main Coronary Bifurcation Lesions
Randomised comparison of Culotte technique versus "Double Kissing" - Crush technique (DK-Crush) for the percutaneous treatment of de novo non-left main coronary bifurcation lesions with modern everolimus-eluting stents (DES) …
- Trial name
- BBK-3 (NCT04192760)
- Testing
- Stenting
- Where
- 13 sites in Germany
- Volunteers
- 400 people
- Sponsor
- University Heart Center Freiburg - Bad Krozingen
Coronary Arteriosclerosis, Myocardial Infarction
Impact of Daylight on Patients With Acute Myocardial Infarction
The study tests if intense light could be a potential therapy in humans after myocardial infarction by inducing Per2.
- Trial name
- NCT02490397
- Testing
- Day Light, Room Light
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Oxidative Stress, Inflammatory Stress
Melatonin Treatment and Inflammation, Oxidative Stress and Autonomic Function in Connection With Surgery
The purpose of this study is to determine whether treatment with melatonin can reduce cell damage and inflammation in connection with laparoscopic gall bladder surgery.
- Conditions
- Oxidative Stress, Inflammatory Stress, Myocardial Ischaemia
- Trial name
- NCT00311259
- Testing
- Melatonin (drug), Laktose
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Contraception, Female Contraception
A Postmarketing Study of the Risk of Venous Thromboembolism (Blood Clots), Myocardial Infarction (Heart Attacks), and Stroke Among Women Using ORTHO EVRA (Norelgestromin and Ethinyl Estradiol Contraceptive Patch) Compared With Women Who Take Oral Contraceptives for Birth Control
The purpose of the study is to use data from a health care information database to assess the risk of venous thromboembolism (blood clots), myocardial infarction (heart attacks), and stroke among women using a transdermal…
- Trial name
- NCT00377988
- Testing
- Transdermal Contraceptive System, Norgestimate-containing oral contraceptives with EE
- Volunteers
- 423 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Thrombosis, Acute Coronary Syndrome
Histopathology of the Aspirated Thrombus During Acute Myocardial Infarction
This study was initiated on the preliminary premise that a thrombus whose formation was triggered by a thrombogenic substrate, such as within an atherosclerotic plaque (Tissue factor initiated thrombus), may evolve differently…
- Trial name
- NCT01705665
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Hillel Yaffe Medical Center
Chronic Kidney Disease, Multivessel Coronary Artery Disease
Randomized Comparison of xiEnce and visioN Coronary Stents in the sAme muLtivessel Patient With Chronic kiDnEy diSease
Percutaneous coronary intervention (PCI) with bare metal stent (BMS) in patients with renal insufficiency has shown unsatisfactory results.
- Trial name
- RENAL-DES (NCT00818792)
- Testing
- Coronary stent
- Where
- 2 sites in Italy
- Volunteers
- 215 people
- Sponsor
- European Hospital
Coronary Artery Disease
Angiography-Derived FFR And IVUS for Clinical Outcomes in Patients With Coronary Artery Disease
Comparison of Angiography-derived Fractional FLow Reserve And IntraVascular Ultrasound-guided Intervention Strategy for Clinical OUtcomes in Patients with CoRonary Artery Disease
- Trial name
- FLAVOUR II (NCT04397211)
- Testing
- Angiography-derived FFR, IVUS
- Where
- 23 sites in China, South Korea
- Volunteers
- 1,872 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Coronary Artery Disease
Effect of Acute Statin Treatment in Patients Undergoing Percutaneous Coronary Intervention
The goal of this study is to determine if one dose of simvastatin will decrease the inflammatory response to coronary intervention.
- Trial name
- NCT00588471
- Testing
- Simvastatin
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Mayo Clinic
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