Clinical trials: Myoma
Uterine Fibroids
Mifepristone to Treat Uterine Fibroids
Objectives: to evaluate the efficacy, safety and quality of life by using 2.5 and mifepristone 5 mg daily doses to treat uterine fibroids over 3 months with a 9 months follow-up period.
- Trial name
- NCT01786226
- Testing
- Oral administration of mifepristone 2.5 mg daily for three months, Oral administration of mifepristone 5 mg daily for three months
- Where
- Cuba
- Volunteers
- 220 people
- Sponsor
- Mediterranea Medica S. L.
Leiomyoma, Uterine, Leiomyoma
Prescription of Letrozole for Uterine Myoma
The PLUM Study is a randomized, double-blinded, 2-arm, parallel-group, placebo-controlled trial is designed to compare the efficacy of letrozole versus placebo on leiomyoma-related symptoms and quality of life as well as…
- Conditions
- Leiomyoma, Uterine, Leiomyoma, Fibroid, Fibroid Uterus
- Trial name
- PLUM (NCT06143631)
- Testing
- Letrozole 2.5mg
- Where
- 5 sites in United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Myoma, Adenomyosis
To Compare to 2-channel and Multiple-channel Single Port Laparoscopic-assisted Vaginal Hysterectomy
The main objective of this trial is to assess the efficacy and safety of single port-access laparoscopic-assisted vaginal hysterectomy.
- Trial name
- NCT01564602
- Testing
- comparison multiple channel port laparoscopic surgery
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Uterine Leiomyoma, Uterine Fibroid
ABSOLUTELY: A Temporary Uterine Blood Supply Occlusion for Laparoscopic Myomectomy in Patients With UTErine LeiomYoma
A phase 3 multicenter unblinded randomized controlled trial comparing the temporary uterine blood supply occlusion with conventional approach during laparoscopic myomectomy in patients with uterine leiomyoma.
- Conditions
- Uterine Leiomyoma, Uterine Fibroid, Leiomyoma, Uterine, Myoma;Uterus
- Trial name
- NCT04519593
- Testing
- Laparoscopic myomectomy with prior temporary uterine blood supply occlusion, Conventional laparoscopic myomectomy
- Where
- Russia
- Volunteers
- 120 people
- Sponsor
- Mother and Child Clinic Saint-Petersburg
Myoma;Uterus, Vitamin D Deficiency
Vitamin D Levels And Myoma Uteri
Women with at least one uterine leiomyoma and polycystic ovary syndrome over 10 mm and women with normal ultrasonographic findings were included in the study.
- Conditions
- Myoma;Uterus, Vitamin D Deficiency, Polycystic Ovary
- Trial name
- NCT03871868
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Uterine Myomas
PGL4001 Versus Placebo in Uterine Myomas
This trial will assess the efficacy and safety of PGL4001 with concomitant iron administration versus placebo with concomitant iron administration, over a 3-month period for the pre-operative treatment of pre-menopausal women…
- Trial name
- PEARLI (NCT00755755)
- Testing
- PGL4001 (ulipristal) and iron
- Where
- 38 sites in Czechia, Hungary and 4 more
- Volunteers
- 241 people
- Sponsor
- PregLem SA
Myoma;Uterus
Intraoperative Carbetocin to Decrease Blood Loss During Hysteroscopic Myomectomy
Submucous myomas represent one of the main indications of operative hysteroscopy. Since 1976 when Neuwirth and Amin reported the first five cases of excision of submucous myomas , several techniques have been developed in order…
- Trial name
- NCT04482959
- Testing
- Carbetocin, Sodium chloride 0.9%
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University Hospital
Cervical Cancer, Ovarian Cancer
Clinical Database and Biobank of Patients With Gynecologic Neoplasms
The database and biobank establishment started in 1997 in our institute. However, the sample size was too small with respect to our clinical and fundamental scientific research's requirement.
- Conditions
- Cervical Cancer, Ovarian Cancer, Endometrial Cancer, Choriocarcinoma
- Trial name
- NCT01267851
- Where
- China
- Volunteers
- 1,600,000 people, healthy volunteers welcome
- Sponsor
- Huazhong University of Science and Technology
Myoma;Uterus, Myomectomy; Surgical Blood Loss
Prevention of HEMOrhagic Risk in Upper MYOmeCTomy by Use of Misoprostol.
In France, uterine fibroids or leiomyomas are the most common benign tumour in women of childbearing age. In 30% of cases, fibroids are symptomatic (menorrhagia, anaemia, pain), in which case surgical management is indicated.
- Trial name
- HEMOMYOC (NCT06882824)
- Testing
- myomectomy with misoprostol
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Clermont-Ferrand
Myoma;Uterus
Transverse vs Longitudinal Incision in Myomectomy
The Aim of the study is to compare between transverse and longitudinal uterine incision in abdominal myomectomy regarding intraoperative blood loss.
- Trial name
- NCT03009812
- Testing
- Longitudinal uterine incision, Transverse uterine incision
- Volunteers
- 52 people
- Sponsor
- Ain Shams University
Uterine Myoma, Uterine Adenomyosis
Single Incision Laparoscopic Surgery (SILS) Versus Conventional Laparoscopic Hysterectomy
Multi-center prospective randomized trial of single port laparoscopic surgery (SILS) versus conventional 3-4 ports laparoscopic hysterectomy.
- Trial name
- NCT01483417
- Testing
- Single incision Laparoscopic hysterectomy, Conventional laparoscopic hysterectomy
- Where
- 8 sites in South Korea
- Volunteers
- 240 people
- Sponsor
- Samsung Medical Center
Fibroid Uterus
Temporary Artery Clipping for Robotically-assisted Myomectomy, a Multicentric Randomized Controlled Trial
This study aims to investigate the efficacy of temporary clipping of the uterine artery and utero-ovarian ligament during robotically assisted myomectomy (RAM) for uterine fibroids.
- Trial name
- TACROM (NCT06269809)
- Testing
- Temporary clipping of the uterine arteries and the utero-ovarian ligmants., No temporary clipping of the uterine arteries and the utero-ovarian ligmants.
- Where
- 4 sites in Belgium, France and 1 more
- Volunteers
- 82 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Uterine Myomas
Vasopressin Versus Epinephrine in Myomectomy
Uterine myomas (fibroids or leiomyomas) are the most common benign tumor of the female genital tract and the leading indication for hysterectomy.
- Trial name
- NCT01861015
- Testing
- Epinephrine, Vasopressin
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- CHA University
Myoma of Uterus, Colon Cancer
Anxiety Before Non-cardiac Surgery in Adults
Adult patients undergoing elective non-cardiac surgery were enrolled. Anxiety before the operation was evaluated by The State Anxiety Inventory (S-AI).
- Conditions
- Myoma of Uterus, Colon Cancer, Gastric Carcinoma, Prostate Cancer
- Trial name
- NCT05596188
- Where
- China
- Volunteers
- 424 people
- Sponsor
- RenJi Hospital
Uterine Leiomyoma
High Intensity Focused Ultrasound in Uterine Myoma
Aim to evaluate the efficacy of safety of newly developed, high intensity focused ultrasound device in women with symptomatic uterine leiomyoma
- Trial name
- NCT03328260
- Testing
- HIFU
- Where
- South Korea
- Volunteers
- 34 people
- Sponsor
- Seoul National University Hospital
Myoma;Uterus, Blood Loss
the Effect of Misoprostol on Intra-operative Blood Loss During Myomectomy Operation
assess the effect of using misoprostol in abdominal myomectomy operations on blood loss, duration of the operation and possible operative complications.
- Trial name
- NCT03483142
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- ahmed nagy shaker ramadan
Rate of Complete Resection in a Unique Surgical Time
Comparison of Two Bipolar Resector in Less Than 3cm Myoma Resection
Hysteroscopic resection of type 0, 1 or 2 myoma is frequent. The more frequent resector used for myoma resection is 26Fr hysteroscope.
- Trial name
- DIAPER (NCT03402516)
- Testing
- 18.5 resector, 26Fr resector
- Where
- France
- Volunteers
- 308 people
- Sponsor
- Bicetre Hospital
Myoma;Uterus, Surgery
Myomectomy Operation and Fundus Incision, Energy Modalities and Methods of Extraction
Myomectomy operation due to myoma uteri is an operation that can cause serious blood loss. For some anatomical reasons, fundal myomas were removed, while a group of investigators recommended the initiation of a longitudinal…
- Trial name
- NCT03901404
- Testing
- Myomectomy Operation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
UTERINE MYOMAS
Assessment of the Manageability and Safety of ADBLOCK Adhesion Barrier System in Laparoscopic Gynaecological Surgery
Adhesions are the most frequent complication of abdominopelvic surgery. They are internal scar tissues which form as a result of surgery which may abnormally join together what were once separate tissues and organs.
- Trial name
- ADBEE (NCT01745432)
- Testing
- ADBLOCK
- Where
- 3 sites in Germany
- Volunteers
- 30 people
- Sponsor
- Terumo Europe N.V.
Endometrial Cancer, Endometrial Diseases
Virtual Reality's Role in See&Treat Hysteroscopy
The aim of the study is to evaluate the feasibility and effectiveness of virtual reality technology in outpatient hysteroscopy to improve pain and anxiety management and spread the diffusion of see \& treat philosophy.
- Conditions
- Endometrial Cancer, Endometrial Diseases, Myoma;Uterus, Endometrial Hyperplasia
- Trial name
- NCT06524934
- Testing
- Use of virtual reality during the hysteroscopic procedure
- Where
- Italy
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Federico II University