Clinical trials: Myopathies
Fibromyalgia, PRESSURE PAIN THRESHOLD
The Effect of Connective Tissue Massage on Pressure Pain Threshold in Fibromyalgia
The aim of this randomized controlled study is to investigate the immediate effect of connective tissue massage (CTM) on the pressure pain threshold (PPT) in women with fibromyalgia.
- Trial name
- NCT07791134
- Testing
- Connective Tissue Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Ankara Yildirim Beyazıt University
Spasticity
Effectiveness of an Interprofessional Approach to the Treatment of Spasticity With Botulinum Toxin & Non-pharmacological Therapies
Many people with neurological conditions will experience spasticity, a nonvolitional and uncontrollable tightening and/or spasm of muscles.
- Trial name
- NCT07160699
- Testing
- Botulinum Neurotoxin Type A, Non-pharmacological therapies
- Where
- 2 sites in Switzerland, United Kingdom
- Volunteers
- 30 people
- Sponsor
- Technical University of Bern
Stroke, Spasticity
Early Injection of Botulinum Toxin on Motor Function and Gait Pattern in Stroke Patients
Spasticity, muscle weakness, abnormal gait pattern are co-morbidities commonly seen in stroke patients. They cause disabled condition of patients in activities of daily life and functional performance, and also accidental falls…
- Trial name
- NCT01817816
- Testing
- Botox_A, Botox_B
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Changhua Christian Hospital
Duchenne Muscular Dystrophy
Clinical Intramuscular Gene Transfer Trial of rAAVrh74.MCK.Micro-Dystrophin to Patients With Duchenne Muscular Dystrophy
The proposed phase I clinical trial is a pilot study to evaluate safety and biological activity of the rAAVrh74.MCK.micro-Dystrophin vector administered by an intramuscular route.
- Trial name
- NCT02376816
- Testing
- rAAVrh74.MCK.micro-Dystrophin
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Jerry R. Mendell
Musculoskeletal Pain
Signal Relief Patch in Musculoskeletal Pain
assess the efficacy of the Signal Relief patch for the management of general musculoskeletal pain
- Trial name
- NCT05288114
- Testing
- Signal Relief Patch
- Where
- 2 sites in United States
- Volunteers
- 44 people
- Sponsor
- Signal Relief
Fibromyalgia
QOL Efficacy of Adapted Physical Activity for Patients With Fibromyalgia
Fibromyalgia affects at least 4% of the population. This chronic painful pathology is a source of social exclusion with a major impact on professional activity; To our knowledge, no study has demonstrated with sufficient evidence…
- Trial name
- NCT03640806
- Testing
- PHYSICAL ACTIVITY
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Primary Fibromyalgia
A Randomized Trial of Oral Iron Therapy in Fibromyalgia
Fibromyalgia (FM) is a disorder with chronic widespread musculoskeletal pain for which no alternative cause can be identified. The condition is often accompanied by other features such as fatigue, stiffness, cold intolerance…
- Trial name
- NCT01820052
- Testing
- Oral Iron
- Where
- India
- Volunteers
- 120 people
- Sponsor
- Sanjay Gandhi Postgraduate Institute of Medical Sciences
Musculoskeletal Pain, Neuropathic Pain
Virtual Reality (VR) Self-Hypnosis Software
This single-site study of self-hypnosis software using an off-the-shelf virtual reality (VR) device (OculusGo™) to determine the software's safety, usability, and preliminary efficacy in pain relief for HIV-associated chronic…
- Conditions
- Musculoskeletal Pain, Neuropathic Pain, Neuralgia
- Trial name
- NCT06398847
- Testing
- Virtual Reality headset
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Myotonic Dystrophy Type 1, Urinary Incontinence
Pelvic Floor Muscle Training for Women with Myotonic Dystrophy
Myotonic dystrophy type 1 (DM1) is a neuromuscular disease characterized by multisystem manifestations. DM1 can affect the urinary system through the impact of the pelvic floor muscles (PFM).
- Trial name
- NCT06316778
- Testing
- Pelvic floor muscle training
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Université de Sherbrooke
Contracture of Muscle, Thigh, Muscle Rigidity
Differents Intensities of Passive Stretching on ROM, Neuromuscular and Performance in Soccer Players: A Blinded RCT
Intensity is a "qualitative" variable of a muscle stretching protocol, which is very little studied due to its inherent characteristic of the individual being stretched.
- Conditions
- Contracture of Muscle, Thigh, Muscle Rigidity, Strain of Hamstring Muscle (Disorder)
- Trial name
- NCT03150563
- Testing
- Passive static stretch
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio Grande do Norte
Sleep Apnea, Obstructive, Hypertension
Epidemiology and Intervention of Obstructive Sleep Apnea Based on Community
This observational study in a real-world community was designed to perform epidemiological investigation and assess effect of CPAP intervention of obstructive sleep apnea.
- Conditions
- Sleep Apnea, Obstructive, Hypertension, Obesity, Diabetes
- Trial name
- NCT03280914
- Testing
- Auto-CPAP
- Where
- China
- Volunteers
- 103 people
- Sponsor
- Guangdong Provincial People's Hospital
Fibromyalgia
The Clinical Effect of Low-Intensity Electromagnetic Field Neurostimulation in Fibromyalgia Syndrome Patients
The purpose of this study is to determine whether persons treated with a low-intensity, noninvasive form of cortical electrical stimulation experience a reduction in symptoms of fibromyalgia different than persons receiving a…
- Trial name
- NCT01180244
- Testing
- Noninvasive cortical electrical stimulation
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- McLaren Regional Medical Center
Duchenne Muscular Dystrophy
Phase I/II Study of PRO044 in Duchenne Muscular Dystrophy (DMD)
The purpose of this study is to see whether PRO044 is safe and effective to use as medication for DMD patients with a mutation around location 44 in the DNA for the dystrophin protein.
- Trial name
- NCT01037309
- Testing
- PRO044 SC, PRO044 IV
- Where
- 4 sites in Belgium, Italy and 2 more
- Volunteers
- 18 people
- Sponsor
- BioMarin Pharmaceutical
Lateral Epicondylitis, Rotator Cuff Syndrome
PLT and Steroid in Lateral Epicondylopathy and Supraspinatus Calcific Tendinopathy
PLT vs. steroid vs. PLT + steroid, which treatment is most effective in lateral epicondylitis (or tennis elbow) and supraspinatus calcific tendinitis.
- Trial name
- NCT05648032
- Testing
- lyophilized platelet (30ng) and triamcinolone acetonide 10mg, lyophilized platelet (30ng), triamcinolone acetonide 10mg
- Where
- Taiwan
- Volunteers
- 180 people
- Sponsor
- National Taiwan University Hospital
Duchenne's Muscular Dystrophy (DMD)
L-citrulline and Metformin in Duchenne's Muscular Dystrophy
The purpose of the study is to show that the intake of L-citrulline and metformin improves muscle function and delay of progression in patients with Duchenne's muscular dystrophy.
- Trial name
- NCT01995032
- Testing
- 750 mg metformin and 7.5 g L-citrulline daily p.o.
- Where
- Switzerland
- Volunteers
- 47 people
- Sponsor
- University Hospital, Basel, Switzerland
Myotonic Dystrophy
A Study to Investigate the Safety, Tolerability, and Efficacy of SAR446268, an Adeno-associated Viral Vector-mediated Gene Therapy in Participants Aged 10 to 55 Years of Age With Non-congenital Myotonic Dystrophy Type 1
This is a Phase 1/Phase 2 open-label single arm, multicenter, and multinational study with SAR446268 for treatment of male and female participants 10 to 55 years old with non-congenital myotonic dystrophy (DM) type 1 (DM1).
- Trial name
- BrAAVe (NCT06844214)
- Testing
- SAR446268
- Where
- 10 sites in United States, Argentina and 4 more
- Volunteers
- 32 people
- Sponsor
- Sanofi
Stroke, Ischemic, Stroke Hemorrhagic
Radial Extracorporeal Shock Wave Therapy and Visual Feedback Balance Training on Lower Limb Post-Stroke Spasticity, Trunk Performance and Balance:
This study assess the relationship between lower limb spasticity and trunk movements during static and dynamic balance in post-stroke patients who also underwent conventional physical therapy, visual feedback balance training and…
- Conditions
- Stroke, Ischemic, Stroke Hemorrhagic, Spasticity as Sequela of Stroke, Spastic Gait
- Trial name
- NCT05196633
- Testing
- radial extracorporeal shock wave therapy
- Where
- Romania
- Volunteers
- 23 people
- Sponsor
- Carol Davila University of Medicine and Pharmacy
Acne, Bites
Implementation of a Minor Ailment Service in Community Pharmacy Practice
Self-care and self-medication are commonly the treatments of choice for the management of minor ailments. Minor ailments can be treated through community pharmacy using a Minor Ailment Service (MAS).
- Conditions
- Acne, Bites, Burns, Cold
- Trial name
- INDICA+PRO (NCT05247333)
- Testing
- Minor ailment service
- Where
- Spain
- Volunteers
- 20,987 people
- Sponsor
- Universidad de Granada
Muscle Cramps in Amyotrophic Lateral Sclerosis
Mexiletine for the Treatment of Muscle Cramps in ALS
The purpose of this study is to determine if mexiletine is effective for the treatment of muscle cramps in Amyotrophic Lateral Sclerosis (ALS).
- Trial name
- NCT01811355
- Testing
- Mexiletine
- Where
- 6 sites in United States
- Volunteers
- 23 people
- Sponsor
- Bjorn Oskarsson, MD
Rhabdomyolysis
Rhabdomyolysis and Robot-assisted Radical Prostatectomy
In patients undergoing robot-assisted radical prostatectomy (RARP), pneumoperitoneum, intraoperative fluid restriction and prolonged Trendelenburg position may cause rhabdomyolysis (RM) due to hypoperfusion in gluteal muscles and…
- Trial name
- NCT02671604
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Umraniye Education and Research Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.