Clinical trials: Myopathy
Myofascial Temporomandibular Disorder, Bruxism, Sleep
Factors Affecting Patients With Myofascial Temporomandibular Disorders
The aim of the study was to assess and compare the relationship between jaw function, neck disability, sleep quality, fatigue, and headache in patients with myofascial Temporomandibular Disorder (TMD) with Sleep Bruxism (SB) and…
- Conditions
- Myofascial Temporomandibular Disorder, Bruxism, Sleep, Sleep Disturbance, Jaw Spasm
- Trial name
- NCT04842136
- Testing
- Scales and indexes
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Shoulder Pain Back Pain Postpartum Period, Back Pain
Effects of Body Mechanics Training on Shoulder-Back Pain and Breastfeeding Ergonomics in Breastfeeding Mothers
The research will be conducted as a randomized controlled trial and mothers in the intervention group will receive training on posture correction,breastfeeding positions, and shoulder and back muscle strengthening movements.
- Conditions
- Shoulder Pain Back Pain Postpartum Period, Back Pain, Postpartum Period
- Trial name
- RCT (NCT07104227)
- Testing
- body mechanics training, to inform
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Ege University
Dupuytren's Disease
Evaluation of Xiaflex: Trial of Effectivenss iN Dupuytren's
This is a prospective, multi-centre, pragmatic randomized controlled trial to compare both the clinical effectiveness and cost-effectiveness of collagenase injections (CI) versus limited palmar fasciectomy (LPF) to determine if…
- Trial name
- EXTEND (NCT02725528)
- Testing
- collagenase injection, limited palmar fasciectomy
- Where
- 10 sites in Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- McMaster University
Cerebral Palsy, Spasticity
Spinal Cord Stimulation for Children With Cerebral Palsy
The goal of this clinical trial is to help understand spinal cord excitability in children with cerebral palsy compared to neurologically typical children.
- Trial name
- NCT07516067
- Testing
- Transcutaneous Spinal Cord Stimulation (tSCS)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Martin Piazza
Intensive Care (ICU) Myopathy
Biomechanical Properties in Intensive Care Unit (ICU) Survivors 12-month After Discharge
Intensive care unit (ICU) admission is associated with muscle weakness and ICU survivors report persevering limitation of physical capacity for years after discharge.
- Trial name
- NCT01364714
- Where
- Denmark
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Duchene Muscular Dystrophy, Becker Muscular Dystrophy
Multiparametric Ultrafast Ultrasound Biomarkers for Duchenne and Becker Muscular Dystrophies
The purpose of this research study is to determine the potential of a multiparametric ultrasound approach to non-invasively monitor disease progression and to serve as an objective outcome measure for future clinical trials in…
- Trial name
- INNOVAN (NCT07378553)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Neck Pain, Extracorporeal Shock Waves Therapy
Effect of Extracorporeal Shockwave Therapy Before Postural Correction Exercise in Adults With Forward Head Posture
Currently, as digital leisure activities increase, more time is spent at home. According to these social trends, it is necessary to establish a program that can safely and effectively perform exercise at home.Therefore, this…
- Conditions
- Neck Pain, Extracorporeal Shock Waves Therapy, Exercise Program
- Trial name
- NCT05855772
- Testing
- Extracorporeal shock waves, Posture Correction Exercise Program
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Sahmyook University
Mitochondrial Myopathies, Mitochondrial Diseases
Mitochondrial Dysfunctions Driving Insulin Resistance
The overarching aim of this observational study is to characterize muscle mitochondrial defects in individuals harboring pathogenic mitochondrial DNA (mtDNA) mutations associated with an insulin-resistant phenotype.
- Conditions
- Mitochondrial Myopathies, Mitochondrial Diseases, Mitochondrial Disorders
- Trial name
- MITO-DYS-IR (NCT06080581)
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Fibromyalgia
Efficacy of Amygdala Retraining With Mindfulness (ART+MF) vs Compassion Therapy (CT) for the Treatment of Patients With Fibromyalgia
Amygdala Retraining Treatment (ART) is a new and promising therapy for patients with Chronic Fatigue Syndrome (CFS) and Fibromyalgia (FM), however, randomized controlled trials (RCT) are scarce.
- Trial name
- NCT02454244
- Testing
- ART with Mindfulness, Mindfulness Compassion, Relaxation
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital Miguel Servet
Proteomics, Exercise
Dynamic Proteomics and Integrated Rates of Muscle Protein Synthesis During an Acute Period of Loading and Unloading
Skeletal muscle plays several different roles in the promotion and maintenance of health and well-being. The loss of muscle mass that occurs with aging, chronic muscle wasting diseases, and physical inactivity puts people at an…
- Conditions
- Proteomics, Exercise, Atrophy, Disuse, Hypertrophy
- Trial name
- HYPAT (NCT04514744)
- Testing
- Knee bracing, Unilateral Resistance Exercise Training
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- McMaster University
Spinal Muscular Atrophy, Duchenne Muscular Dystrophy
Public AttitudesTowards SMA and DMD Awareness, Newborn and Carrier Screening and Physiotherapy Practices
The addition of SMA and DMD muscle diseases to newborn screening and premarital carrier screening has been controversial. In this study, researchers aim to measure the awareness level of SMA and DMD muscle diseases of individuals…
- Conditions
- Spinal Muscular Atrophy, Duchenne Muscular Dystrophy, Healthy Individuals
- Trial name
- NCT05110885
- Testing
- Questionnaire
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Tendinopathy, Jumper's Knee
A Study of the Effect of Time-of-day of Training on Chronic Patellar Tendinopathy
The study is a 12-week human study where 60 participants with chronic patellar tendinopathy (more than 3 months symptoms duration) are randomised to undergo 12 weeks of targeted resistance exercise either in the morning or in the…
- Trial name
- TENDOTIME (NCT06217432)
- Testing
- Resistance training for knee extensors
- Where
- Denmark
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Muscle Weakness, Muscle Atrophy
Effect of Neuromuscular Electrical Stimulation Combined With Blood Flow Restriction on Muscular and Cardiovascular Function
Neuromuscular electrical stimulation (NMES) has recently been combined with blood flow restriction (BFR) in controlled trials and has shown increased muscular strength and size compared with NMES and BFR on their own.
- Trial name
- NCT03662555
- Testing
- Neuromuscular electrical stimulation
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- St. Mary's University, Twickenham
Muscle Disorder, Trigger Point Pain, Myofascial
Electromyographic´s Differences Between Dry Needling in Tonic or Phasic Skeletal Muscle Fibers.
The aim of this study is to compare the surface electromyography (EGM) changes between dry needling in the upper trapezius, is a prevalence tonic fiber or lower trapezius is a prevalence phasic fiber.
- Trial name
- NCT03813485
- Testing
- Dry Needling in upper trapezius, Dry Needling in lower trapezius
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universidad Francisco de Vitoria
Reactive Airways Dysfunction Syndrome (Disorder), Muscle Weakness
Efficacy of Inspiratory Muscle Training on Elite Swimmers
This study is a randomized controlled trial on the efficacy of inspiratory muscle training on swimming performance, airway dysfunction and perceived breathlessness in elite swimmers.
- Conditions
- Reactive Airways Dysfunction Syndrome (Disorder), Muscle Weakness, Dyspnea
- Trial name
- PEAK (NCT03062735)
- Testing
- Inspiratory Muscle Training
- Where
- Portugal
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Stroke, Spasticity, Muscle
Analysis of the Correlation Between Ultrasound Imaging and Functional Parameters in the Medial Gastrocnemius Muscle in Post-stroke Patients With Spasticity in the Lower Limb
The goal of this observational study is to understand the impact of spasticity on muscle changes and functional performance in stroke patients with lower limb spasticity in comparison to non-stroke individuals.
- Trial name
- US-function (NCT06411587)
- Testing
- Ultrasound imaging and functional assessment
- Where
- Spain
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Cervical Myofascial Pain Syndrome, Chronic Neck Pain
Type D Personality, and Stigma in Myofascial Pain Syndrome
Cervical myofascial pain syndrome is a chronic musculoskeletal condition characterized by the presence of sensitive trigger points and taut muscle bands, resulting in localized or referred pain, muscle stiffness, and limited…
- Conditions
- Cervical Myofascial Pain Syndrome, Chronic Neck Pain, Type D Personality, Psychological Distress
- Trial name
- NCT07292155
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Gulseren Demir Karakilic
Trigger Finger
Percutaneous Release vs Steroid Injection for Trigger Finger
Trigger fingers (TF) is the common cause of pain and disturbed function of hand. Many studies show that percutaneous release of A1 pulley has better outcome than the steroid injection.
- Trial name
- NCT05383040
- Testing
- Percutaneous release
- Where
- Nepal
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Armed Police Force Hospital, Nepal
Fibromyalgia
Effect of Low-impact Aerobic Exercise and Music Therapy in Fibromyalgia
The idea of this study is the combination of these two techniques (low-impact aerobic exercise through functional movements and music therapy) that have proven to be effective separately.
- Trial name
- EffMusFibro (NCT02516761)
- Testing
- Low-impact aerobic exercise combined with music therapy, Low-impact aerobic exercise, Control group
- Where
- Spain
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Critical Illness Polyneuromyopathy
Reference Values for Compound Muscle Action Potential Amplitude Obtained by Direct Muscle Stimulation
Direct muscle stimulation (DMS) method is one of the electrodiagnostic methods used in the diagnosis of critical illness myopathy (CIM) and critical illness neuropathy (CIN).
- Trial name
- NCT04227548
- Testing
- needle electromyography
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Adana City Training and Research Hospital
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