Clinical trials: Myopia, Moderate
Myopia
Study on the Effect of Mitomycin C 0.02% on the Corneal Endothelial After Photorefractive Keratectomy in Moderate Myopia
In this study 126 eyes in 63 patients with moderate bilateral myopia and astigmatism between -3 and -5 (SE difference between two eyes should not be more than 0.75 and the residual corneal thickness>350 μ ) were entered in the…
- Trial name
- NCT00999973
- Testing
- Mitomycin C 0.02%
- Where
- Iran
- Sponsor
- Shahid Beheshti University of Medical Sciences
MODERATE AND HIGH MYOPIA
A Comparison of Photorefractive Keratectomy (PRK), PRK With Mitomycin-C and Laser Subepithelial Keratomileusis (LASEK) in the Treatment of Moderate and High Myopia
The purpose of this study is to assess whether there is a significant difference in visual outcomes or corneal haze after surface ablation for moderate and high myopia in active duty service members treated with PRK, Mitomycin-C…
- Trial name
- NCT00415077
- Testing
- PRK, MMC PRK, LASEK
- Where
- United States
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Medical Center
Myopia
A Singapore Study to Assess How Neurovision Improve the Vision of Adults With Low to Moderate Myopia
To evaluate the efficacy of NeuroVision NVC vision correction technology to improve the vision of subjects with Low and Moderate Myopia in Asian eyes in Singapore
- Trial name
- NCT00348075
- Testing
- Neurovision
- Where
- Singapore
- Sponsor
- Singapore National Eye Centre
Refractive Error
The Evolutionary Model of Mild-to-moderate Myopia in China
Myopia has emerged as a major health issue in east Asia, because of its increasingly high prevalence in the past few decades (now 80-90% in school-leavers), and because of the sight-threatening pathologies associated with high…
- Trial name
- NCT02667509
- Where
- China
- Volunteers
- 852,441 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Myopia
Study of the MEL 80 Excimer Laser Using LASIK in the Treatment of Moderate to High Myopia
The purpose of this study is to determine whether the MEL 80 Excimer Laser is effective in the treatment of moderate to high myopia (nearsightedness), when used as part of the Laser In Situ Keratomileusis (LASIK) procedure.
- Trial name
- NCT00762541
- Testing
- MEL 80 Treatment of High Myopia
- Where
- 5 sites in United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec, Inc.
Must be PRK Candidate
Safety and Efficacy of Lotemax Versus FML in Subjects Undergoing PRK for the Correction of Mild to Moderate Myopia, 3- Month Follow-up Study
STUDY OBJECTIVE: To evaluate and compare the safety and efficacy of (corneal Wound Healing and Intraocular Pressure) Fluorometholone and Loteprednol after photorefractive keratectomy (PRK) surgery.
- Trial name
- NCT02974387
- Testing
- Fluorometholone(FML), Loteprednol (Lotemax)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Dr Salouti Eye Research Center
Myopia
Efficacy of LASIK Versus PRK in Asians With Mild and Moderate Myopia
Laser in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK) are currently the 2 main refractive surgeries to correct myopia which are being performed worldwide, with more patients preferring LASIK to PRK because of…
- Trial name
- NCT00348049
- Testing
- Laser in Situ Keratomileusis (LASIK), Photorefractive Keratectomy (PRK)
- Where
- Singapore
- Sponsor
- Singapore National Eye Centre
Myopia
An Evaluation of Outcomes Following Wavefront Optimized or Wavefront Guided Lasik Procedure in Low to Moderate Myopic Patients
To compare post-surgical outcomes in patients who have undergone Wavefront Guided LASIK (iLASIK platform) compared with patients who have undergone Wavefront Optimized LASIK (Wavelight Allegretto 400 Hz platform).
- Trial name
- NCT01173198
- Testing
- WAVEFRONT Optimized LASIK, WAVEFRONT GUIDED LASIK
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Innovative Medical
Myopia
the Correlation Between Visual Quality After SMILE and LASEK in Patients With Moderate to Low Myopia
1. Study the changes in subjective visual quality, contrast sensitivity, and total ocular aberrations of patients with low-to-moderate myopia after SMILE and LASEK surgeries at different age groups; 2.
- Trial name
- SMILE LASEK (NCT07260786)
- Where
- China
- Volunteers
- 100 people
- Sponsor
- yuhao shao
Lasik in Myopia
Visumax Femtolasik Versus Moria M2 Microkeratome in Myopia
this is an interventional prospective clinical study which was conducted to evaluate the efficacy, safety, predictability, ocular aberrations, and flap thickness predictability of Visumax femtosecond laser (FSL) compared to Moria…
- Trial name
- NCT03193411
- Testing
- Visumax femtosecond laser, Moria M2 microkeratome (MK)
- Volunteers
- 30 people
- Sponsor
- Dar Al Shifa Hospital
Myopia
Initial Evaluation of Photorefractive Keratectomy in U.S. Army Personnel
The objective of this study is to conduct a prospective clinical trial to evaluate the safety and efficacy fo the VISX Excimer Laser system for the treatment of naturally occurring low to moderate myopia, with or without low…
- Trial name
- NCT00413673
- Testing
- PRK
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Medical Center
Conventional LASIK, Femto-LASIK and PRK in Low and Moderate Myopia
Changes of Higher-Order Aberrations After Different Types of LASIK in Myopia
This prospective comparative interventional study will enroll patients with low and moderate myopia who seek laser vision correction at Sohag Center for LASIK and Corneal Surgeries, Sohag, Egypt.
- Trial name
- NCT06860061
- Testing
- Laser refractive surgery
- Volunteers
- 60 people
- Sponsor
- Sohag University
Corneal re-Epithelialization
A Study to Assess the Safety, Tolerability and Effect of Nexagon™ Applied to the Eye After PRK Laser Eye Surgery for Nearsightedness
Phase 1 randomized, prospective, double-masked, vehicle-controlled, dose-escalation study to evaluate the safety, tolerability and clinical effect of Nexagon™ in subjects following bilateral PRK for the correction of mild to…
- Trial name
- NCT00654550
- Testing
- Nexagon™ or Nexagon™ vehicle
- Where
- New Zealand
- Volunteers
- 24 people
- Sponsor
- OcuNexus Therapeutics, Inc.
Myopia, Myopia, Moderate
Software Refraction With Mobilerone Versus Retinoscopy
Software refraction in the mobilerone for myopia and astigmatism is a novel medical device for myopia adults and elder children with or without astigmatism.
- Conditions
- Myopia, Myopia, Moderate, Astigmatism
- Trial name
- SRMR (NCT06059521)
- Testing
- Software refraction with Eye Test Technology in a mobilerone, Retinoscopy
- Where
- 3 sites in China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Beijing Airdoc Technology Co., Ltd.
Moderate or Severe Vision Impairment, Both Eyes
The Effectiveness of Portable Electronic Vision Enhancement Systems (p-EVES) for Near Vision in Visual Impairment
Over 1 million people in the UK suffer from untreatable visual impairment, many of them elderly. The major complaint of visually impaired people is their inability to carry out simple tasks, especially those involving reading.
- Trial name
- p-EVES (NCT01701700)
- Testing
- portable electronic magnifier, optical aids
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Manchester University NHS Foundation Trust
Myopia
Atropine (0.02%, 0.04%) Combined With Defocus DIMS for Moderate and High Myopia Control
To evaluate the effectiveness and safety of DIMS, low concentration atropine eye drops,and atropine combined with DIMS in controlling axial length and refraction in children with moderate to high myopia.
- Trial name
- atropine (NCT06523504)
- Testing
- DIMS, The 0.02% ATP Group, The 0.04% ATP Group
- Where
- China
- Volunteers
- 410 people
- Sponsor
- Ruihua Wei
Myopia
A Study Assessing the Efficacy and Safety of DE-127 Ophthalmic Solution in Subjects With Mild or Moderate Myopia (APPLE)
To investigate the safety and efficacy of three concentrations of DE-127 ophthalmic solution when compared to Placebo in subjects diagnosed with mild or moderate myopia. To investigate the dose response of DE-127.
- Trial name
- NCT03329638
- Testing
- DE-127 Ophthalmic Solution low dose, DE-127 Ophthalmic Solution medium dose, DE-127 Ophthalmic Solution high dose
- Where
- Singapore
- Volunteers
- 99 people
- Sponsor
- Santen Pharmaceutical Co., Ltd.
Myopia, Moderate, Myopic Astigmatism
A Prospective, Randomized Clinical Study of Two Phakic Toric Implantable Lenses
Primary Objective: To compare the efficacy and the residual refractive error of EYECRYLTM Phakic toric versus Visian® Toric ICL in moderate to high myopic patient with co-existing astigmatism.
- Conditions
- Myopia, Moderate, Myopic Astigmatism, Myopia, Degenerative
- Trial name
- NCT06839898
- Testing
- EYECRYLTM Phakic Toric Intraocular Lens Treatment Arm, Visian® Toric ICL Treatment Arm
- Where
- 4 sites in Germany, India
- Volunteers
- 172 people
- Sponsor
- Biotech Healthcare Holding Gmbh
Myopia, Moderate
To Compare the Clinical Outcomes of FemtoLASIK and ICL Implantation in Treating Moderate Myopia Focusing on Refractive Stability, Contrast Sensitivity and High Order Aberrations.
Compare the clinical outcomes of FemtoLASIK and ICL implantation in treating moderate myopia.
- Trial name
- NCT07291986
- Testing
- FemtoLASIK, ICL implantation
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Walid Osama Abdel Rahman Nour El Din
Refractive Error, Myopia
Silicone Hydrogel Contact Lenses on Low Astigmatism in Japan
This study seeks to evaluate the clinical performance of a recently released contact lens designed to correct astigmatism to an established contact lens that has historically been used in these patients.
- Conditions
- Refractive Error, Myopia, Astigmatism
- Trial name
- NCT00639353
- Testing
- senofilcon A toric soft contact lens, senofilcon A sphere soft contact lens
- Where
- 10 sites in Japan
- Volunteers
- 102 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.