Clinical trials: Myopia
Myopia Progression
Prospective Research on the Intervention of Myoless2.0 Effectiveness (PRIME) in Pediatric Population
The Goal of the study is to evaluate the rate of myopia progression with open ring myopia control spectacle lens designs compared to a commercial peripheral plus myopia control spectacle lens (CML) in European children with…
- Trial name
- PRIME (NCT07394556)
- Testing
- myopia control lens
- Where
- 3 sites in Portugal, Spain and 1 more
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Indizen Optical Technologies, S.L.U.
Myopia, Hyperopia
Corneal Epithelial Thickness Mapping by Anterior Segment Optical Coherence Tomography in Patients With Refractive Errors
This study evaluates corneal epithelial thickness using anterior segment optical coherence tomography (AS-OCT) in patients with refractive errors.
- Conditions
- Myopia, Hyperopia, Astigmatism, Emmetropia
- Trial name
- NCT07647146
- Where
- Egypt
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Sohag University
Nearsightedness
Measuring the Peripheral Optical Quality of The Eye
The goal of the study is to quantify wavefront aberration profiles of the eye with and without contact lens across the visual field. This will enable us to investigate the impact of the aberration on retinal image quality.
- Trial name
- NCT03479827
- Testing
- Monofocal Contact Lens, Bifocal Contact Lens
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Myopia
Evaluating the Performance of Precision1 Daily Disposable Contact Lens in a Group of Heavy Digital Device Users
The purpose of this study is to evaluate the performance of Precision1 DD CLs with regard to subjective symptoms (dryness, comfort, vision), lens fit and time to haze in CL wearers who identify themselves as heavy digital devices…
- Trial name
- PUG (NCT04201639)
- Testing
- Verofilcon A contact lenses
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Myopia
Soft Contact Lens Fitting With Different Sagittal Height
To evaluate whether there is a difference in subjective and objective fit of soft lenses with different sagittal height
- Trial name
- NCT05962528
- Testing
- Soft lens
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Myopia
Effect of Axial Length of the Globe on Retinal Nerve Fibre Thickness
the goal of this obsrevational study is to learn about retinal nerve fibres and if their numbers changed with axial length of the globe or not.
- Trial name
- NCT05716776
- Testing
- Optical coherence tomography (OCT)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sohag University
Presbyopia, Refractive Errors
Evaluation of the Safety and Effectiveness of Aceclidine (LNZ101) and Aceclidine + Brimonidine (LNZ100) in the Treatment of Presbyopia
To evaluate the safety and effectiveness of Aceclidine/Brimonidine (LNZ101) compared with Aceclidine (LNZ100) and vehicle in the treatment of Presbyopia.
- Conditions
- Presbyopia, Refractive Errors, Eye Diseases
- Trial name
- NCT05431543
- Testing
- Aceclidine+Brimonidine combination ophthalmic solution, Aceclidine ophthalmic solution, Vehicle proprietary ophthalmic solution
- Where
- 5 sites in United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- LENZ Therapeutics, Inc
Myopia
Visual Outcomes and Contrast Sensitivity After Myopic LASIK
Evaluate visual outcomes and contrast sensitivity for subjects undergoing bilateral myopic LASIK procedure using the 200 kHz WaveLight® FS200 Femtosecond Laser and the WaveLight® Allegretto Wave® Eye-Q Laser.
- Trial name
- NCT01746589
- Testing
- bilateral myopic LASIK
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Daniel S. Durrie, MD
Dark Focus of Accommodation
Night Myopia and Dark Focus of Accommodation
Shifts in accommodation at decreasing luminance levels are considered as principle cause for night myopia. Previous studies with laser optometers quantified the dark focus of accommodation up to 3 D.
- Trial name
- NCT03358550
- Testing
- Accommodation Measurement
- Where
- Germany
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Applied Sciences Jena
Low Vision, Age Related Macular Degeneration
Early Feasibility Study Using IOPCL MAG to Improve Near Vision in ARMD Subjects
This early feasibility study aims to improve near vision in subjects 55 years or older who have a clinical diagnosis of Age-Related Macular Degeneration.
- Trial name
- NCT04984590
- Testing
- IOPCL AMD MAG
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- OnPoint Vision Inc
Myopia
Comparative Study of the Wearing Satisfaction of Two Soft Contact Lens Designs.
To evaluate the wearing satisfaction of a new design of the PureVision soft contact lenses.
- Trial name
- NCT00768885
- Testing
- PureVision 1, PureVision 2
- Where
- Japan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Myopia, Hyperopia
Clinical Investigation of the Vision-R800 Device.
Randomized, bilateral, cross-over dispensing study of a standard and VR800 refraction and associated spectacle lenses.
- Conditions
- Myopia, Hyperopia, Astigmatism, Presbyopia
- Trial name
- NCT04208750
- Testing
- Vision R-800 Phoropter, Standard Phoropter
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Pete Kollbaum, OD, PhD
Myopia, Astigmatism
Wavefront-guided LASIK Surgery Compared to Ray Tracing-Guided LASIK Surgery
We are enrolling participants aged 22 and older to have LASIK surgery in both eyes. We will perform wavefront-guided LASIK in one eye and ray tracing-guided LASIK in the fellow eye of each participant.
- Trial name
- NCT07078799
- Testing
- LASIK
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Stanford University
Myopia, Progressive
Management of Myopia in University Students Using Dual Focus Soft Contact Lenses
The purpose of the study is to quantify the effectiveness of Coopervision MiSight contact lenses in slowing the rate of myopia progression in university students.
- Trial name
- MoMUS (NCT05955638)
- Testing
- MiSight contact lenses, Proclear contact lenses
- Where
- 2 sites in United Kingdom
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Bradford
Myopia
Safety and Effectiveness of Wavefront-Guided LASIK Corrections of Myopic Refractive Errors
The purpose of this clinical trial is to demonstrate that wavefront-guided LASIK is safe and effective for the correction of myopic refractive errors.
- Trial name
- NCT01663363
- Testing
- LASIK correction of myopic refractive errors
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Refraction Error, Myopia
The MORE Study: Manifest vs. Online Refraction Evaluation
The assessment of the refractive state of the eye is a fundamental and important part of ophthalmic and optometric clinical practice.
- Conditions
- Refraction Error, Myopia, Astigmatism
- Trial name
- MORE (NCT03313921)
- Testing
- Online Manifest Refraction
- Where
- Netherlands
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Myopia
Daily Low-level Red Light and 0.01% Low-dose Atropine for Myopia Prevention
To compare the preventive effects of daily low-level red-light and 0.01% low-dose atropine eye drops on myopia.
- Trial name
- NCT06727019
- Testing
- low-level red-light, Atropine (0.01%)
- Where
- China
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Myopia
Screening for Hyperopic Reserve in Kindergarten
Screening for hyperopic reserve among senior kindergarten children is an important population-based eye health measure. Hyperopic reserve refers to physiological hyperopia in young children, which acts as a natural buffer against…
- Trial name
- NCT07851532
- Where
- China
- Volunteers
- 134,000 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Presbyopia, Near Vision
Phase 3 Safety Study of LNZ100 and LNZ101 for the Treatment of Presbyopia Subjects
Safety Study of the Long-Term Safety of LNZ100 \& LNZ101 in Presbyopic Subjects
- Conditions
- Presbyopia, Near Vision, Refractive Error, Eye Diseases
- Trial name
- NCT05753189
- Testing
- Aceclidine+Brimonidine combination ophthalmic solution, Aceclidine ophthalmic solution, Vehicle
- Where
- 40 sites in United States
- Volunteers
- 362 people, healthy volunteers welcome
- Sponsor
- LENZ Therapeutics, Inc
Myopia
Electronic Spectacles Versus Low Dose Atropine in Young Myopes
This is a bilateral, dispensing, masked, randomized clinical trial. Myopic children will be randomly assigned to one of the following: (1) Investigational clinical prototype (CP1) device without atropine, (2) Investigational CP1…
- Trial name
- NCT06034379
- Testing
- eSpectacle Clinical prototype (CP1) device, 0.01% atropine
- Where
- Taiwan
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Kubota Vision Inc.