Clinical trials: NETs
Malaria, Mosquito Repellent
Effect of a Combined Use of Mosquito Repellent and Insecticide Treated Net on Malaria in Ethiopia
The combined use of a mosquito repellent and long lasting insecticidal nets (LLINs) by household members would result in a 40% reduction in malaria prevalence compared with households that only use LLINs.
- Conditions
- Malaria, Mosquito Repellent, Long Lasting Insecticidal Nets
- Trial name
- NCT01160809
- Testing
- Mosquito repellent
- Where
- Ethiopia
- Volunteers
- 6,082 people, healthy volunteers welcome
- Sponsor
- Malaria Consortium, Ethiopia
Malaria
Evaluation of Insecticide Treated Nets and Wall Liners for the Prevention of Malaria
The purpose of this study is to determine whether insecticide treated wall liners, in combination with insecticide treated nets, reduce the incidence of malaria infections compared to insecticide treated nets alone.
- Trial name
- MTC-ITWL (NCT01043796)
- Testing
- Insecticide treated nets and wall liners, Insecticide treated nets alone
- Where
- Kenya
- Volunteers
- 1,730 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Malaria, Anemia
Efficacy of Two Dual Active Ingredient Long Lasting Insecticidal Nets for Control of Malaria Transmitted by Pyrethroid Resistant Vectors in Benin
The massive scale-up of Long Lasting Insecticidal Nets (LLIN) has led to a major reduction in malaria burden (up to 50%) in many sub-Saharan African countries.
- Trial name
- NNP (NCT03931473)
- Testing
- Bed nets
- Where
- Benin
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Malaria
Impact of School-based Delivery of Long Lasting Insecticide Nets
Insecticide-treated nets (ITNs), and more recently long lasting insecticide nets (LLINs), have been shown to effectively protect those groups most biologically vulnerable to the burden of malaria across Africa.
- Trial name
- NCT00878397
- Testing
- School-based delivery of long lasting insecticide nets
- Where
- Kenya
- Volunteers
- 5,113 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Heated Tobacco Products, Microcirculation
Cardiovascular Effects of Heated Tobacco Products (HTP)
This is a human randomized controlled cross-over study where the effects of heated tobacco products (HTP) on vascular function, microcirculation and thrombosis is assessed.
- Conditions
- Heated Tobacco Products, Microcirculation, Thrombosis, Vascular Function
- Trial name
- ISMOKE (NCT04550026)
- Testing
- HTP inhalation
- Where
- Sweden
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Necrotizing Enterocolitis (NEC)
NETs: Protection or Harm in Neonatal Inflammation or Infection
This is a prospective in vitro cell biology study of polymorphonuclear leukocyte (PMN) protein synthesis in response to PAF. PMNs from cord blood of premature human infants at risk for NEC (birth weight between 501 - 1500 grams)…
- Trial name
- NCT00747851
- Where
- United States
- Volunteers
- 388 people, healthy volunteers welcome
- Sponsor
- University of Utah
Gastroenteropancreatic Neuroendocrine Tumors
Study For Evaluating The Value Of A Multi Biomarker Approach In Metastatic GEP NETs
This exploratory study aims to evaluate the diagnostic, prognostic and response predictive value of a multi biomarker strategy in patients with Gastroenteropancreatic Neuroendocrine Tumors (GEP NETs) originating from the midgut…
- Trial name
- EXPLAIN (NCT02630654)
- Testing
- This is a non-interventional study. Patients will be treated with any intervention deemed appropriate by the patient's physician.
- Where
- 25 sites in Denmark, Estonia and 5 more
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- Ipsen
Malaria
Repellents as Added Control Measure to Long Lasting Insecticidal Nets
The scaling up of Long Lasting Insecticidal Nets (LLIN) and the expansion of Indoor Residual Spraying (IRS) has contributed to a significant decrease of malaria worldwide.
- Trial name
- MalaResT (NCT01663831)
- Testing
- Mosquito topical repellent
- Where
- Cambodia
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Institute of Tropical Medicine, Belgium
ARDS
The Evaluation of NETs, Caspase-1 and Cytokines in ARDS Patients
1. enrollment criteria and clinical data collection: follow the principles of medical ethics, the development of inclusion and exclusion criteria, select 90 cases of ARDS patients, in the active treatment at the same time…
- Trial name
- NCT03227107
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Xiangya Hospital of Central South University
Malaria
Net Transition Initiative: Efficacy of Two Next-generation Nets for Control of Malaria in Cote d'Ivoire
The investigator plan to conduct a three-arm cluster-randomized control trial which compares two next generation of long-lasting Insecticidal Nets (LLINs); Veeralin®LLIN (PBO-py LLIN), Interceptor G2 (chlorfenapyr-py LLIN) to a…
- Trial name
- NCT05796193
- Testing
- Alpha-cypermethrin and PBO LLIN, Alpha-cypermethrin and Clorfenapyr LLIN, Alpha-cypermethrin only LLIN
- Where
- Côte d’Ivoire
- Volunteers
- 1,650 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Neuroendocrine Tumors
Diagnosis and Staging of Neuroendocrine Tumors (NETs) Utilizing 68Ga-DOTATOC PET/CT Scan
The primary goal of the analysis is to estimate the diagnostic accuracy of Gallium 68 (68Ga) -DOTATOC PET/CT for detecting neuroendocrine tumors (NETs) compared to conventional imaging techniques such as Magnetic Resonance…
- Trial name
- NCT03136328
- Testing
- 68Ga-DOTATOC
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Malaria, Anemia
Uganda Housing Modification Study
To explore housing modification as a malaria control intervention, and to assess the degree to which it may offer protection in moderate to high malaria endemicity settings, we propose a two-phase study evaluating epidemiological…
- Trial name
- UHMS (NCT04622241)
- Testing
- Eave Tubes, Eave Ribbons, Full House Screening
- Where
- Uganda
- Volunteers
- 2,422 people, healthy volunteers welcome
- Sponsor
- Infectious Diseases Research Collaboration, Uganda
Malaria, Anaemia
Efficacy of Three Novel Bi-treated Long Lasting Insecticidal Nets
The massive scale-up of Long Lasting Insecticidal Nets (LLIN) has led to a major reduction in malaria burden (up to 50%) in many sub-Saharan African countries.
- Trial name
- NCT03554616
- Testing
- Chlorfenapyr LLIN, pyriproxyfen LLIN, Piperonyl butoxide LLIN
- Where
- Tanzania
- Volunteers
- 4,200 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine