Clinical trials: NIRS
Healthy Elderly
Innovative Hand Rehabilitation System With Synchronized Contralateral Haptic Feedback
Previous studies have found that graded motor imagery (GMI) training can provide continuous activation of the cerebral cortex compared to traditional rehabilitation therapy.
- Trial name
- NCT07077460
- Testing
- TIPr, Mirror Visual Feedback Device, Mirror Visual Feedback Device(Blocked mirror)
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Healthy
Evaluation of the Impact of Laterality on Brain Activation During a Virtual Mirror Therapy Task in Healthy Subjects
The aim of this study is to investigate the differences in brain activation in healthy subjects during virtual mirror therapy tasks, depending on the laterality of the task.
- Trial name
- LARTHEMIRS (NCT05793762)
- Testing
- Left virtual mirror therapy task, Right virtual mirror therapy task
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Régional d'Orléans
Heart Defects, Congenital
Congenital Heart Defects and NIRS
Congenital Heart Defects and NIRS
- Trial name
- NCT03411512
- Where
- Slovenia
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Petja Fister, MD, PhD
Oxygen Deficiency
Validation of Next Generation Cerebral and Tissue Oximeter
This is a validation study of a near-infrared spectroscopy (NIRS) device designed to measure the cerebral tissue oxygen saturation.
- Trial name
- NCT03128372
- Testing
- Desaturation
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Mental Fatigue, Near Infrared Spectroscopy
The Effect of Mental Fatigue on the Cerebral Oxygenation During Endurance Exercise
The experiment will consist of 3 consecutive trials performed in a sound-insulated climate chamber (20°C and 40% RH) at the VUB. Participants will be asked to return 3 successive weeks.
- Conditions
- Mental Fatigue, Near Infrared Spectroscopy, NIRS, Condition
- Trial name
- NCT05355493
- Testing
- Time to Exhaustion cycling test, Go/NoGo task
- Where
- Belgium
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Preterm Birth, Oxygen Toxicity
Fetal Haemoglobin and Cerebral and Peripheral Oxygenation.
The aim of this study is to investigate the relationship between cerebral and peripheral oxygenation and oxygen extraction, as measured by NIRS (near-infrared spectroscopy ), and the FHbF (fraction of fetal hemoglobin) and…
- Conditions
- Preterm Birth, Oxygen Toxicity, Fetal Hemoglobin
- Trial name
- HbFIN (NCT04802629)
- Testing
- Near-infrared spectroscopy
- Where
- Austria
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Acute Compartment Syndrome
Ability of Near Infrared Spectroscopy to Isolate Compartments of the Extremity
Near infrared spectroscopy (NIRS) provides a non-invasive means of continuously monitoring tissue oxygenation, which may be useful for diagnosis of acute compartment syndrome (ACS).
- Trial name
- NCT01283451
- Testing
- Muscle contraction
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- J&M Shuler
Iron, Cerebral Blood Flow
16 Weeks' Dietary Supplementation With Iron and Iron + Vitamin C on Cerebral Blood Flow and Energy Expenditure in Women of Reproductive Age
Iron deficiency is the most prevalent nutritional deficiency worldwide with one in four estimated to be affected by iron deficiency anaemia.
- Conditions
- Iron, Cerebral Blood Flow, Energy Metabolism, Cognitive Function
- Trial name
- NCT04477018
- Testing
- Iron bis-glycinate chelate and vitamin C, Iron bis-glycinate chelate
- Where
- United Kingdom
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Healthy
Evaluation of the Impact of Laterality on Cerebral Activation During a Motor Task of the Upper Limb in Healthy Subjects
The aim of this study is to investigate the differences in brain activation in healthy subjects during motor tasks, depending on the laterality of the subject, the laterality of the task and the complexity of the task.
- Trial name
- Lateralinirs (NCT05428917)
- Testing
- Simple task, complex task
- Where
- France
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Régional d'Orléans
Hypoxia, Exercise
Physiological Characteristics of High Altitude Climbers
Climbing at high altitude and tolerating hypoxic environment require specific physiological adaptations. Large intersubjects differences exist regarding the ability to adapt to high altitude and hypoxia.
- Conditions
- Hypoxia, Exercise, Sport Performance
- Trial name
- ALTIPERF (NCT02880150)
- Testing
- Stress test
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Tissue Oxygenation Measurement
OxyPrem Validation Study
The precision of the novel diagnostic near-infrared spectroscopy (NIRS) device for the measurement of tissue oxygenation and hemoglobin concentration (OxyPrem) is assessed by repeated measurements.
- Trial name
- NCT04860401
- Testing
- Measurement of tissue oxygenation with novel diagnostic near-infrared spectroscopy device (OxyPrem) (no clinical decisions based on oxygenation levels)
- Where
- Switzerland
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Hans Ulrich Bucher
Healthy Volunteers, Working Memory Task
Non-invasive Optical Low-frequency Oscillation Study of the Prefrontal Cortex Based on fNIRS
The investigators aimed to investigate the effects of different cognitive load tasks (1-back, 2-back, 3-back) on low-frequency oscillations (LFOs) in the prefrontal cortex of healthy young individuals, analyze the relationship…
- Conditions
- Healthy Volunteers, Working Memory Task, Cognition
- Trial name
- NCT07759648
- Testing
- N-back Visual working memory task
- Where
- China
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College
Healthy
Impact of Dietary Flavanols on Microvascular Function in Young Females During Mental Stress
The aim of this project is to examine whether flavonoids, which are small molecules naturally present in cocoa, as well as fruits and vegetables such as berries, tea, citrus fruits, apple (typically responsible for giving these…
- Trial name
- NCT07864545
- Testing
- High-flavanol cocoa powder, Low-flavanol cocoa powder
- Where
- United Kingdom
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Microcirculatory Status, Spectroscopic Analysis
Near-Infrared Spectroscopy Measurements in Chronic Obstructive Pulmonary Disease
Participants were selected based on three groups: healthy, chronic obstructive pulmonary disease, and chronic renal disease. NIRS was used to measure tissue oxygenation on the thenar region of the right hand.
- Conditions
- Microcirculatory Status, Spectroscopic Analysis, COPD, Renal Failure
- Trial name
- NIRS (NCT06976762)
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Neonatal Opioid Withdrawal, Neonatal Opioid Withdrawal Syndrome
Cerebral Physiology of NOWS
This study will use a new device to measure blood flow and oxygen levels in the brains of newborn infants who have had exposure to opioid medications in the womb, compared to newborns who have not had any exposure.
- Conditions
- Neonatal Opioid Withdrawal, Neonatal Opioid Withdrawal Syndrome, Opioid Use Disorder, Intrauterine Exposure
- Trial name
- NIRS for NOWS (NCT07610746)
- Testing
- FD-NIRS and DCS
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Indiana University
Cerebral Oxygenation, Peripheric Oxygenation
The Measurement Of Cerebral Oxygenisation With NIRS Method İn Polycythaemic Infants Might Add A Criterion To Indicate PPET?
Near infrared spectrophotometry (NIRS) offers the possibility of noninvasive and continuous bedside investigation of cerebral , renal, mesenteric and peripheric oxygenation and hemodynamics, and changes in newborn period.The aim…
- Conditions
- Cerebral Oxygenation, Peripheric Oxygenation, Polycythaemic Infants
- Trial name
- NCT01255618
- Testing
- INVOS 5100
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Healthy Male and Female Subjects, Healthy Volunteer Study
Near-InfraRed Spectroscopy of Auricular Stimulation
This is a single-visit non-invasive study of healthy volunteer subjects. Brain activity will be measured with infra-red light sensors attached to a cap worn on the head, while both ears are gently stimulated with plastic…
- Trial name
- NIRAS (NCT06825364)
- Testing
- auricular stimulation
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Syncope
Multi-Site Near Infrared Spectroscopy (NIRS) Monitoring of Children During Tilt Table Testing
PURPOSE OF THE STUDY This study will explore the use of multi-site NIRS monitoring during tilt table testing, combining somatic and cerebral saturations data with hemodynamic data to establish the non-invasive assessment of…
- Trial name
- NIRS & Tilt (NCT00659464)
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Symptoms of Anxiety
Transcranial Photobiomodulation in Anxiety Disorders
The investigators have previously shown that safe, non-invasive methods of brain stimulation such as the administration of transcranial infrared light can result in improvements to cognition and emotion.
- Trial name
- NCT07133893
- Testing
- Attention bias assessment and modification, Transcranial photobiomodulation
- Where
- United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Francisco Gonzalez-Lima, PhD
Transcutaneous Nerve Stimulation
Effect of Transcutaneous Nerve Stimulation on Primary Motor Cortex to Modulate Cortical Excitability and Hemodynamic Response During Implicit Motor Learning: A TMS and NIRS Study
Noninvasive brain stimulation was recently gradually be emphasized. The electrical current applied on scalp can effective modulate cortical excitability.
- Trial name
- NCT02115841
- Testing
- "Enraf-Nonius" Muscle stimulator
- Where
- Taiwan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Chang Gung University