Clinical trials: NIRS
Myofascial Pelvic Pain
NIRS for the Diagnosis of Myofascial Pelvic Pain
Myofascial Pelvic Pain (MPP) is an often-misdiagnosed condition affecting up to 26% of women during their lives and imposing enormous costs on national health care systems.
- Trial name
- NCT07181447
- Testing
- Pelvic Floor Muscle Assessment by Near-Infrared Spectroscopy
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Extremely Premature Newborn (Born Before 32 Weeks' Gestation)
Description of Changes in NIRS as a Function of Ductus Arteriosus Status in Very Premature Babies Born Before 32 WG at the DIJON University Hospital
Monitoring patent ductus arteriosus is currently performed using echocardiography, an operator-dependent examination which requires holding the child on their back and which is potentially time-consuming.
- Trial name
- CAPNIRS (NCT06153771)
- Testing
- Collection of brain and kidney NIRS measurements, echocardiography
- Where
- France
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Adverse Effect, Cerebral Perfusion
Investigation Of The Effects Of Unilateral And Bilateral Spinal Anesthesia On Cerebral Blood Flow
Spinal anesthesia is a widely used method in anesthesia practice. Unilateral spinal block refers to a neuroaxial technique that induces motor and sensory blockade on the surgical side.
- Trial name
- NCT06871449
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nuh Naci Yazgan University
Stroke
Novel Brain Signal Feedback Paradigm to Enhance Motor Learning After Stroke
Stroke (795,000/year in the US and 30 million existing stroke survivors in the world) damages brain neural structures that control coordinated upper limb movement.
- Trial name
- NCT02856035
- Testing
- Neural feedback plus FES and motor training
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Healthy, Ageing
Can Cocoa Flavanols Protect Endothelial Function During Prolonged Sitting in Healthy Older Adults?
Sitting time is high in older adults and has been shown to temporarily impair endothelial function and blood pressure. Flavanols, plant-derived compounds, acutely enhance endothelial function and reduce Blood pressure in older…
- Trial name
- NCT07265869
- Testing
- High-flavanol cocoa powder, Low-flavanol cocoa powder
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Parkinson Disease
Comparison of Different Non-invasive Electrical Stimulation Protocols to Facilitate Rehabilitation in Parkinson's Disease Subjects With Postural Instability and Gait Disorders
The trial will include 51 adult participants with Parkinson's disease and postural instability and gait disorders (PD-PIGD) and 20 age- and sex-matched healthy controls.
- Trial name
- NCT06868160
- Testing
- Rehabilitation, tDCS, tsDCS (first cycle)
- Where
- Italy
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Stroke, Hemiparesis;Poststroke/CVA
Muscle Oxygenation and Spasticity in Hemiparetic Stroke Patients
Conditions such as hemiparesis, sensory and motor impairment, perceptual impairment, cognitive impairment, aphasia, and dysphagia may be observed after stroke.
- Conditions
- Stroke, Hemiparesis;Poststroke/CVA, Spasticity as Sequela of Stroke
- Trial name
- NCT06362954
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ankara Medipol University
Chronic Obstructive Pulmonary Disease
Difference in the Metabolic Characteristics of COPD Patients and Healthy Adults
Although some important progresses were made in the field of the meridian research, no breakthroughs have been achieved. Besides,there are some problems in meridian researches.
- Trial name
- NCT04046666
- Testing
- Functional near infrared spectroscopy, Moxibustion
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Zhejiang Chinese Medical University
Magnetic Resonance Imaging
Development of MRI Protocols and Associated Explorations (EEG, NIRS) in Healthy Volunteers
The main objective of the studies that will be carried out on volunteer patients who have given their consent will be the development and optimization of the sequence parameters or the design of the stimulation paradigms in order…
- Trial name
- MAP-VS (NCT03152539)
- Testing
- MRI, EEG, NIRS
- Where
- France
- Volunteers
- 733 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Breast Carcinoma, Kidney Carcinoma
Functional Near-Infrared Spectroscopy and Virtual Reality Relaxation Programs for Pain Management in Patients With Cancer
This study aims to develop objective tools for assessing perceived pain severity in cancer patients and survivors, evaluate the sustained effectiveness of non-pharmacological interventions such as virtual reality in reducing pain…
- Conditions
- Breast Carcinoma, Kidney Carcinoma, Carcinoma
- Trial name
- NCT06456411
- Testing
- Functional Near-Infrared Spectroscopy, Questionnaire Administration, Virtual Technology Intervention
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Microcirculatory Status, Spectroscopic Analysis
Near-Infrared Spectroscopy Measurements in Chronic Obstructive Pulmonary Disease
Participants were selected based on three groups: healthy, chronic obstructive pulmonary disease, and chronic renal disease. NIRS was used to measure tissue oxygenation on the thenar region of the right hand.
- Conditions
- Microcirculatory Status, Spectroscopic Analysis, COPD, Renal Failure
- Trial name
- NIRS (NCT06976762)
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Cerebral Desaturation, Cerebral Ischemia
Assessment of Cerebral Blood Flow Asymmetry in Cardiac Surgery Patients Undergoing Hypothermic Circulatory Arrest
Cerebral oxygen desaturation during cardiac surgery measured using near infrared spectroscopy (NIRS) derived cerebral oximetry has been associated with significant postoperative morbidity.
- Trial name
- COASTLINE (NCT03215589)
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Healthy
Evaluation of the Impact of Laterality on Cerebral Activation During a Motor Task of the Upper Limb in Healthy Subjects
The aim of this study is to investigate the differences in brain activation in healthy subjects during motor tasks, depending on the laterality of the subject, the laterality of the task and the complexity of the task.
- Trial name
- Lateralinirs (NCT05428917)
- Testing
- Simple task, complex task
- Where
- France
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Régional d'Orléans
Ischemic Stroke, Acute, Post-stroke Anxiety
Benson Relaxation for Anxiety, Depression, and Insomnia After Stroke
Stroke is a leading cause of disability worldwide. Many patients experience anxiety, depression, and sleep disturbances in the early recovery phase, which can slow rehabilitation.
- Conditions
- Ischemic Stroke, Acute, Post-stroke Anxiety, Post-stroke Depression, Sleep
- Trial name
- BRT-Stroke (NCT07731282)
- Testing
- Benson Relaxation Technique, Structured Health Education
- Where
- 2 sites in China
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Changchun University of Traditional Chinese Medicine
Lower Urinary Tract Symptoms, Overactive Bladder
Uro-NIRS Clinical Study
The purpose of this experiment is to confirm the results of previous testing of Urodynamix's Uro-NIRS device. Together Urodynamix and Laborie have created a device that includes standard Laborie medical equipment and the…
- Trial name
- Uro-NIRS (NCT00706407)
- Testing
- Fully integrated Uro-NIRS:UDS
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Stroke
fNIRS for Monitoring Cortical Activity in Stroke Recovery
This clinical trial aims to investigate the mechanisms of brain reorganization underlying motor recovery following end-effector (EE) and exoskeleton (Exo) robot-assisted hand training in individuals with stroke.
- Trial name
- NCT07623512
- Testing
- Robot-assisted therapy (EE or EXO system) and functional training
- Where
- Taiwan
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Acute Compartment Syndrome
Use of Near Infrared Spectroscopy to Detect Muscle Perfusion in the Lower Extremity of Uninjured Subjects
Acute compartment syndrome (ACS) is a complication of lower leg trauma that occurs when the pressure inside the leg due to swelling exceeds the body's ability to provide blood to the muscle of the leg.
- Trial name
- NCT01284023
- Testing
- Shaving
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- J&M Shuler
Cerebral Oxygen Desaturation, Post-operative Delirium
Cerebral Oxygenation in Total Hip Arthroplasty Patients
We plan to investigate the relationship between hypotensive epidural anesthesia for hip arthroplasty and cerebral oxygen saturation.
- Trial name
- THANIRS (NCT02325154)
- Testing
- Cerebral Oximeter
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Hearing Loss
Use of Functional Near-infrared Spectroscopy to Investigate Role of Human Auditory Cortex Plasticity and Multi-sensory Integration on Cochlear Implant Performance After Single-sided Deafness
The timing of brain changes that may influence hearing rehabilitation within human A1 after single-sided deafness (SSD) is not known. The goal is to determine when A1 neural plasticity occurs following SSD onset.
- Trial name
- NCT03713554
- Testing
- FNIRS Observational
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Michigan
Primary Progressive Aphasia(PPA)
Targeted Transcranial Magnetic Stimulation to Improve Language and Speech in Patients With Primary Progressive Aphasia
This is a monocenter randomized controlled clinical trial with cross-over arm - assessor blinded. The aims is investigating the effects of the speech language therapy (SLT) alone vs SLT + non-invasive brain stimulation (STIM)…
- Trial name
- NCT06921265
- Testing
- Training with Speech Language Therapy, Standard rTMS, Targeted rTMS
- Where
- Italy
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele