Clinical trials: Nasal Cannula
Critically Illness
The Efficiency of HHHFNC Between Unheated Oxygen Therapy in Difficult Weaning Patients After Extubation in RCC
The purpose of this study is to assess the efficacy of Heated Humidified High-Flow Nasal Cannula compared with noninvasive positive-pressure ventilation in the prevention of extubation failure in patients with prolonged…
- Trial name
- HHHFNC (NCT04564859)
- Testing
- Heated Humidified High-Flow Nasal Cannula
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Respiratory Insufficiency
High Flow Nasal Cannula Versus Nasal Continuous Positive Airway Pressure
The purpose of this study is to compare two common methods of providing respiratory support: nasal continuous airway pressure and high flow nasal cannula to see what effect it has on babies breathing.
- Trial name
- NCT01531465
- Testing
- Pulmonary Function Testing & esophageal pressure monitoring, Pulmonary function testing and esophageal pressure
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Compare Preoxygenation Methods in Bariatric Patients
Preoxygenation With High Flow Nasal Cannula Prolongs Normoxia Time During Induction of Anaesthesia of Bariatric Patients and is Superior to Conventional Preoxygenation With Face Mask.
To compare preoxygenation for induction of general anaesthesia with High Flow Nasal Cannula vs preoxygenation with face mask in patients undergoing bariatric surgery.
- Trial name
- NCT04965610
- Testing
- Preoxygenation with High Flow Nasal Cannula, Preoxygenation via face mask
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Staedtisches Klinikum Karlsruhe
COVID 19
Use of the Nasal Cannula During COVID-19
The objective of this investigation is to determine the incidence of the use of the low flow nasal cannula in suspected or confirmed cases with Covid-19
- Trial name
- NCT04376580
- Where
- Argentina
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tiva Group
Swallowing Disorder, Respiratory Insufficiency
The Impact of High-Flow Nasal Cannula on Swallow Function
Background: High-flow nasal cannula (HFNC) is a non-invasive heated and humidified oxygen delivery device that is capable of delivering high-flow rates.
- Trial name
- NCT03590457
- Testing
- Airvo 2; High-Flow nasal cannula system
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Apneic; Oxygenation
Apneic Oxygenation With a Nasal Cannula in the Obese and Morbidly Obese Surgical Patient
This prospective, randomized, double-blind study is intended to enroll a total of 100 patients with a BMI ≥ 40 kg/m2 and another 100 patients with a BMI ≥ 30 kg/m2 (but less than 40 kg/m2) undergoing surgery with general…
- Trial name
- NCT03671837
- Testing
- Oxygen, Air
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Healthy Volunteers
Physiological Effects of High-flow Nasal Cannula During Exercise
The high-flow nasal cannula (HFNC) has increased its evidence in patients during pulmonary rehabilitation. These studies hypothesize that the physiological effects of HFNC (positive expiratory pressure, anatomical dead space…
- Trial name
- NCT05550935
- Testing
- High-flow Nasal Cannula
- Where
- Chile
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Healthy Volunteers
Gas Composition in the Oropharynx During High-flow Oxygen Therapy Through Nasal Cannula in Healthy Volunteers
Observational, randomized studies and their meta-analyses have shown the high effectiveness of high-flow oxygen therapy through nasal cannulas, reaching 50-60% in acute hypoxemic respiratory failure.
- Trial name
- NCT06189716
- Testing
- High flow oxygen through nasal cannula
- Where
- Russia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Respiratory Failure, Re-intubation Rate
High Flow Nasal Cannula Versus Non Invasive Positive Pressure Ventilation in Reducing The Rate of Reintubation
This is study aim to compare between high flow nasal canula (HFNC) and non invasive positive pressure ventilation (NIPPV) in reducing the rate of reintubation in mechanically ventilated patient with successful weaning
- Trial name
- NCT06029699
- Testing
- high flow nasal cannula, non invasive positive pressure ventilation
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Bronchopulmonary Dysplasia, Prematurity
Impact of Extended CPAP on Bronchopulmonary Dysplasia
The purpose of this pilot study is to compare if keeping infants on CPAP (continuous positive airway pressure) support for an extended period of time until they are 32 weeks corrected gestational age or 1250 grams (approximately…
- Trial name
- NCT05547139
- Testing
- Protocolized weaning of respiratory support
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Respiratory Distress, Lung Injury
Infant Pulmonary Mechanics: High Flow Nasal Cannula Versus Nasal CPAP
This study is designed to evaluate the effect of heated humidified high flow nasal cannula (HHHFNC) as compared to noninvasive nasal continuous positive airway pressure (NCPAP) on lung function as a measure of lung injury in…
- Trial name
- NCT01939067
- Testing
- Heated Humidified High Flow Nasal Cannula, Nasal Continuous Positive Airway Pressure
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Pediatric
The Effect of Education on Nurses' Knowledge About High-flow Nasal Cannula Oxygen Therapy
This study was conducted to evaluate the oxygen therapy methods used in pediatric services and to specify the roles and responsibilities of nurses in the application of HFNC, which is one of these methods.
- Trial name
- NCT05362279
- Testing
- Training
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Hypoxemia
The Effects of Flow Settings During High Flow Nasal Cannula for Adult Hypoxemia Patients
High flow nasal cannula (HFNC) delivers oxygen at a flow which exceeds the patient's inspiratory flow demand in order to improve oxygenation.
- Trial name
- NCT03738345
- Testing
- HFNC flow
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Apnoeic Oxygenation
Positive Airway Pressure Under Apnoeic Oxygenation With Different Flow Rates in Nasal Cannula Therapy
The main objective of this explorative observational study is to investigate the pressures in infraglottic airway and the pharynx provided by THRIVE , using flows ranging from 1l/min to 80 l/min, in patients hospitalized for…
- Trial name
- PAPUA-Flow (NCT03738722)
- Testing
- Oxygen
- Where
- Switzerland
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Healthy
Evaluation of Lung Deposition of Aerosol Via HFNC in Healthy Adults
The aerosol associated with noninvasive ventilation (NIV) and high flow therapy with nasal interface have been employed in an attempt to relieve respiratory distress and optimize the deposition of drugs by inhalation.
- Trial name
- NCT02519465
- Testing
- 10l/min, 30l/min, 50l/min
- Where
- Brazil
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Respiratory Failure With Hypoxia
Clinical Comparison of Flow Regulated Nasal Oxygen Delivery System (FRNDS) Cannula and Plethysmography Belts
SUMMARY: This is a quantitative, non-inferiority study using healthy participants to compare tidal volumes at rest measured by both a standard RIP belt and a flow-regulated nasal oxygen delivery system FRNDS cannula.
- Trial name
- FRNDS (NCT06713213)
- Testing
- Flow-regulated nasal oxygen delivery system (FRNDS)
- Where
- 2 sites in United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Healthy Volunteers
Examining the Effects of Nasal High Flow Oxygen Therapy Compared to Non-invasive Ventilation in Health Volunteers
Respiratory failure is characterized by low levels of oxygen and high levels of carbon dioxide in the blood which causes difficulty breathing.
- Trial name
- NCT03902639
- Testing
- Phase 1 and 2, Phase 3
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
High Flow Nasal Cannula
Work of Breathing and Oxygen Saturation in Infants Receiving High Flow Nasal Cannula (HFNC)
The purpose of this study is to compare work of breathing on different levels of high flow respiratory support on infants born between 27 and 37 weeks gestation.
- Trial name
- NCT03529994
- Testing
- Enrollment
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Fluid Overload
Effect of High-Flow Nasal Cannula on IVC Measurements Using Point of Care Ultrasound
The size of the inferior vena cava (IVC) using point of care ultrasound is used in resuscitation of patients who are critically ill and is now being used as a standard part of resuscitation in many clinical situations.
- Trial name
- NCT05264454
- Testing
- high flow nasal cannulae
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
End-Expiratory Lung Impedance, Respiratory Rate
Asymmetrical High Flow Nasal Cannula and End-Expiratory Lung Impedance
Objective: The primary aim is to assess end-expiratory lung impedance (EELI) changes during the application of high-flow oxygen therapy using asymmetric nasal cannulae, comparing conditions with the mouth closed and open in…
- Conditions
- End-Expiratory Lung Impedance, Respiratory Rate, Diaphragm Thickness Fraction, Diaphragm Excursion
- Trial name
- EELI and AHFNC (NCT06674629)
- Testing
- High flow oxygen therapy
- Where
- Argentina
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Argentinian Intensive Care Society