Clinical trials: Nasal Reconstruction
Paranasal Sinus Diseases, Nasal Diseases
Design of an Augmented Reality System by Integration of CT Scan or MRI Data With Endoscopic Images for Video-assisted Endonasal Endoscopic Surgery
The gold standard surgical treatment for benign nasosinus pathologies is endoscopic surgery. This surgery has experienced considerable growth over the last 30 years.
- Conditions
- Paranasal Sinus Diseases, Nasal Diseases, Lacrimal Apparatus Diseases
- Trial name
- NORA (NCT04968561)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Clermont-Ferrand
Alveolar Cleft Operated on an Alveolar Bone Graft
Alveolar Bone Graft Cortical Nasal Floor
Alveolar bone graft is one of the main step of the surgical care of the patients who are suffering from cleft lip and palate. They are usually performed before the lateral incisor eruption, at about 5 years old and using…
- Trial name
- NCT03883373
- Testing
- alveolar bone graft with cancellous bone and a cortical block, alveolar bone graft with cancellous bone only
- Where
- France
- Volunteers
- 302 people
- Sponsor
- University Hospital, Montpellier
FESS Operation
Intratracheal Dexmedetomidine Versus Lidocaine for Smooth Tracheal Extubation
compare the efficacy of intratracheal dexmedetomidine versus intratracheal lidocaine in achieving smooth tracheal extubation in patients undergoing Functional Endoscopic Sinus surgery and reconstructive nasal surgeries under…
- Trial name
- NCT07504497
- Testing
- dexmedetomidine Lidocaine Saline
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Younes Ahmed Younes
Nasal Valve Compromise
Nasal Dilator Strips for Rhinoplasty
In this study, the study team will investigate the validity and role of nasal dilator strips (NDS), a novel method to determine the site of nasal valve compromise (NVC), in the pre-operative evaluation.
- Trial name
- NCT02787421
- Testing
- Breathe-Rite Nasal Dilator Strip
- Where
- United States
- Sponsor
- Emory University
Head and Neck Cancer, Pain, Musculoskeletal
Continous Popliteal Block for Microvascular Free Flap Reconstruction in Ear, Nose and Throat Surgery
The aim of the study is to assess the effects of a continuous popliteal block on postoperative pain and recovery after major ear, nose and throat surgery with microvascular free flap reconstruction using a fibula graft.
- Trial name
- NCT03607227
- Testing
- Levobupivacaine, Saline Solution
- Where
- Sweden
- Volunteers
- 24 people
- Sponsor
- Region Skane
Arhinia
Nasal Reconstruction Using a Customized 3D-printed Nasal Stent for Congenital Arhinia
A 7-year-old arhinia patient receives nasal reconstruction with nasal cavity reconstruction and is aided with the application of a 3D-printed nasal stent to prevent nasal cavity constriction.
- Trial name
- NCT02559050
- Testing
- Customized 3D-printed nasal stent
- Volunteers
- 1 people
- Sponsor
- Seoul St. Mary's Hospital
Maxillary Sinus Neoplasms
Temporalis Myofascial Flap Effectiveness
This research is conducted as trial to improve lifestyle of patients with cranio-maxillofacial defects following major insults like trauma or tumor resection in form of speech problems or dysphagia by usage temporalis myofascial…
- Trial name
- NCT05298969
- Testing
- Temporalis Myofascial flap
- Where
- Egypt
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Assiut University
Carcinoma
Nasal Reconstruction FACE-Q : French Validation of the Nasal Reconstruction FACE-Q Questionnaire for Reconstruction/Rehabilitation Following Nasal Skin Cancer
This study aims to validate a French version of the Nasal Reconstruction FACE-Q questionnaire for patients who have undergone nasal reconstruction or prosthetic rehabilitation after surgery for nasal skin cancer.
- Trial name
- NCT07257094
- Testing
- operated patients, Control
- Where
- 9 sites in France
- Volunteers
- 346 people
- Sponsor
- Hôpital NOVO
Ear Deformities, Acquired, Ear; Deformity, Congenital
Evaluation of the Auryzon Devices in the Optimization of Ear and Nose Reconstruction Procedures
This study evaluates the efficacy of the AuryzoN devices in the ear and nose reconstruction surgeries, both in terms of operative time and overall quality of reconstruction.
- Conditions
- Ear Deformities, Acquired, Ear; Deformity, Congenital, Microtia, Nose Deformity
- Trial name
- NCT03624608
- Testing
- AuryzoN Family of Devices
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Reconstrata, LLC
Surgical Wound
Reconstruction Flaps for Nasal Surgical Wounds RCT
The purpose of this study is to determine whether there is a significant difference in aesthetic and functional outcomes between nasalis sling flaps and lobed flaps of nasal tip wounds requiring reconstruction.
- Trial name
- NCT04729231
- Testing
- Nasalis Sling Flap, Lobed Transposition Flap
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwestern University
Nasal Septum Perforation
Nasal Septal Flap for Donor Site Reconstruction
The purpose of this study is to demonstrate the utility of porcine small intestinal submucosa (SIS) as a graft material that may aid in the natural healing process of freshly exposed bone and cartilage in the nasal cavity.
- Trial name
- NCT03159624
- Testing
- Biodesign™ SIS graft, Doyle silastic sheet
- Volunteers
- 47 people
- Sponsor
- University of Alabama at Birmingham
Alveolar Cleft
Reconstruction of Nasal Floor for Three-dimensional Repair of Alveolar Cleft
reconstruction of alveolar cleft with autogenous bone after elevation of mucoperiosteal flap and suturing of nasal floor and palatal flap
- Trial name
- NCT06294522
- Testing
- reconstruction of alveolar cleft
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Tanta University
Septoplasty, Rhinoseptoplasty
Study of the Biomechanical and Histological Properties of Septal, Auricular, and Costal Cartilage in the Context of Optimizing Total Nasal Reconstruction
The purpose of the study is to understand the biomechanical properties of septal cartilage as well as the cartilages used in nasal reconstruction and to identify them histologically.
- Conditions
- Septoplasty, Rhinoseptoplasty, Rib Grafting, Otoplasty
- Trial name
- Biom-CARTHIS (NCT07717138)
- Testing
- Analysis of the biomechanical properties of septal cartilage as well as the cartilages used in nasal reconstruction and their histological identification.
- Where
- France
- Volunteers
- 33 people
- Sponsor
- Hôpital NOVO
Plastic Surgery Procedures
Non-surgical Rhinoplasty After Nasal Skin Cancer Reconstruction: Enhancing Aesthetic Outcomes
Reconstruction of the nasal pyramid after skin cancer is a complex surgery, often involving multiple stages. For some patients, the final result may be considered insufficient, affecting their quality of life and leading to…
- Trial name
- NCT07094620
- Testing
- Non-surgical rhinoplasty
- Where
- France
- Volunteers
- 6 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Skin Carcinoma
Tissue Engineered Nasal Cartilage for Reconstruction of the Alar Lobule
The purpose of this study is to investigate the safety and feasibility of implanting an engineered cartilage graft, obtained by culturing expanded autologous nasal chondrocytes within a collagen type I/III membrane, in the alar…
- Trial name
- NCT01242618
- Testing
- engineered nasal cartilage graft
- Where
- Switzerland
- Volunteers
- 5 people
- Sponsor
- University Hospital, Basel, Switzerland
Nasal Surgical Procedures, Regenerative Medicine
Regenerative Medicine Approach to Nasal Reconstruction
The purpose of this study is to gather information on the safety and effectiveness and compare nasal reconstruction standard planning versus 3D preoperative scanning/printing/planning.
- Trial name
- NCT05273060
- Testing
- 3D Nasal Reconstruction Planning
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Nose Cancer, Rhinectomy
Functional and Aesthetic Comparison of Surgical Nasal Reconstruction Versus Nasal Prosthesis (Epithesis) After Total or Subtotal Nasal Amputation
CERNAS is a prospective, multicenter, non-interventional study comparing the functional and aesthetic outcomes of two rehabilitation strategies after total or subtotal nasal amputation: surgical reconstruction (primarily…
- Trial name
- CERNAS (NCT07674030)
- Testing
- SCHNOS score
- Where
- 4 sites in France
- Volunteers
- 20 people
- Sponsor
- Hôpital NOVO
Nasal Septum
Bone Substitute in the Multi Traumatized Nasal Septum Reconstruction
The aim of this project is to evaluate the safety and efficacy of the biomaterial made of HAP/TCP (BCP, Kasios®), in septoplasties of multi traumatized human nose.
- Trial name
- NASEPT (NCT01234415)
- Testing
- Rhinoplasty
- Where
- 3 sites in France
- Volunteers
- 26 people
- Sponsor
- University Hospital, Bordeaux
Postoperative Bleeding, Skin Cancer Face
Tranexamic Acid in Nasal Mohs Reconstruction
This study will be a prospective randomized control trial to evaluate the effects of subcutaneously administered TXA among patients undergoing nasal Mohs reconstruction with local flaps at VUMC.
- Trial name
- NCT06057675
- Testing
- Treatment (tranexamic acid and 1% lidocaine with 1:100,000 epinephrine), Control (1% lidocaine with 1:100,000 epinephrine)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Nasal Valve Collapse, Nose Enhancement
Cartilage Remodeling Using Low-Temperature Radiofrequency for Nasal Airway Reconstruction
The goal of this study is to evaluate the efficacy of using the Vivaer low-temperature radio-frequency (LTRF) device to reshape ex-vivo human nasal or auricular cartilage for use in cosmetic and functional septorhinoplasty.
- Trial name
- NCT07032675
- Testing
- Low-temperature radio-frequency reshaping of autologous cartilage nasal and/or auricular cartilage
- Where
- 6 sites in United States
- Volunteers
- 20 people
- Sponsor
- Indiana University