Clinical trials: Nasal Surgery
Postoperative Pulmonary Atelectasis, Surgery
Prophylactic nCPAP in the PACU Following Elective Laparotomy for Bowel Surgery
The purpose of this study is to determine whether prophylactic nasal continuous positive airway pressure (nCPAP) in the post-anaesthesia care unit (PACU) improves post-operative pulmonary function following elective bowel…
- Trial name
- NCT02077842
- Testing
- Nasal Continuous Positive Airway Pressure, Low Flow Oxygen
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Saskatchewan
Sleep Apnea, Obstructive Sleep Apnea
Effect on Sleep of Surgical Treatment of Severe Nasal Obstruction
The aim of the study is to evaluate the effect of nasal desobstruction surgery (septoplasty, septorhinoplasty or total ethmoidectomy) on sleep quality, assessed by the variation of the Wake after sleep onset (WASO), in patients…
- Conditions
- Sleep Apnea, Obstructive Sleep Apnea, Nasal Obstruction
- Trial name
- SOMNOSE (NCT05582070)
- Testing
- actigraphy
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Bordeaux
Computed Tomography-guided Nasotracheal Intubation, The Space Where the Tube Will be Passed in the Internal Nasal Valve Region
Computed Tomography-Guided Nasotracheal Intubation Procedure
Background: Nasotracheal intubation can lead to severe complications like epistaxis with excessive bleeding. The advancement difficulty of the tube faced during nasal intubation is one of the fundamental causes of this condition.
- Trial name
- NCT05525754
- Testing
- computed tomography-guided nasotracheal intubation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Nasal Obstruction, Turbinate Surgery
Turbinate Volume Reduction Under Local Anesthesia: Randomized Clinical Trial; Our Experience
The purpose of this trial is to know which method is better in delivering radiofrequency waves for hypertrophied turbinates: coblation or RavoR technique? Researchers will compare both techniques in randomized blinded manner…
- Trial name
- NCT06612450
- Testing
- turbinate surgery
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Kafrelsheikh University
Skin Cancer, Non-Melanoma, Skin Cancer Melanoma
Interpolated Flap Study
The primary purpose of this study is to address the limited knowledge regarding patient well- being and nasal function after interpolated flap repair of post-Mohs surgical defects on the nose.
- Conditions
- Skin Cancer, Non-Melanoma, Skin Cancer Melanoma, Mohs Micrographic Surgery
- Trial name
- NCT04164550
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- University of Pennsylvania
Pancreatic Fistula, Pancreaticoduodenectomy
Effect of Trans-Nasal Afferent Loop Decompression on Post-Pancreaticoduodenectomy Pancreatic Fistula
Postoperative pancreatic fistula (POPF) is a major complication and an important cause of mortality after pancreaticoduodenectomy (PD).
- Conditions
- Pancreatic Fistula, Pancreaticoduodenectomy, Complication of Surgical Procedure
- Trial name
- NCT04989868
- Testing
- Trans-Nasal Afferent Loop Decompression, Without Trans-Nasal Afferent Loop Decompression
- Where
- China
- Volunteers
- 299 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Diagnostic, Procedures and Surgeries on or Through Accessible Mucous Membranes
Topical Application of Cocaine HCl 4% and 10% on Safety and Efficacy in Local (Topical) Anesthesia
This study aims to evaluate topical application of Cocaine HCl 4% and 10% on safety and efficacy in local (topical) anesthesia for diagnostic procedures and surgeries on or through accessible mucous membranes of the nasal…
- Conditions
- Diagnostic, Procedures and Surgeries on or Through Accessible Mucous Membranes, of the Nasal Cavities
- Trial name
- NCT01746940
- Testing
- Cocaine HCl 4% Topical Solution, Cocaine HCl 10% Topical Solution
- Where
- 2 sites in United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Lannett Company, Inc.
Stage III Sinonasal Squamous Cell Carcinoma AJCC v6 and v7, Stage IVA Sinonasal Squamous Cell Carcinoma AJCC v7
Chemotherapy Before Surgery and Radiation Therapy or Surgery and Radiation Therapy Alone in Treating Patients With Nasal and Paranasal Sinus Cancer That Can Be Removed by Surgery
This phase II trial studies how well chemotherapy before surgery and radiation therapy works compared to surgery and radiation therapy alone in treating patients with nasal and paranasal sinus cancer that can be removed by…
- Trial name
- NCT03493425
- Testing
- Carboplatin, Cisplatin, Docetaxel
- Where
- 154 sites in United States
- Volunteers
- 82 people
- Sponsor
- ECOG-ACRIN Cancer Research Group
Chronic Rhinosinusitis (CRS) With and Without Nasal Polyps
Paclitaxel-Coated Balloon Treatment of Chronic Rhinosinusitis
This is a prospective, multicenter, randomized, controlled, double-blind clinical trial enrolling 300 adult subjects with chronic rhinosinusitis (CRS) with and without nasal polyps (CRSwNP and CRSsNP) indicated for endoscopic…
- Trial name
- RESTORE-2 RCT (NCT07290140)
- Testing
- Airiver ESSpand DCB, ESS
- Where
- 10 sites in United States
- Volunteers
- 300 people
- Sponsor
- Airiver Medical, Inc.
Colorectal Cancer
Robotic Versus Laparoscopy NOSE for Stage I-III Left-sided Colon Cancer
In this project, the investigator aims to provide the level 1 evidence for the comparison of robotic versus laparoscopic NOSE for the surgery of stage I-III colorectal cancer.
- Trial name
- NCT05970133
- Testing
- Colectomy with NOSE procedure
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- National Taiwan University Hospital
Sore-throat, Nasopharyngeal Pack
Effect of Oropharyngeal Pack Soaked in Ketamine or Magnesium Sulphate on Post Operative Sore Throat After Nasal Surgery
The aim of this study is to compare the effect of ketamine or magnesium sulphate soaked throat pack on the incidence and severity of post operative sore throat as a primary outcome, post operative nausea and vomiting as a…
- Conditions
- Sore-throat, Nasopharyngeal Pack, Nasal Surgery, Nausea and Vomiting, Postoperative
- Trial name
- NCT05714540
- Testing
- Ketamine Hydrochloride ,Magnesium sulphate and saline 0.9%
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Rhinosinusitis
Early Versus Late Surgical Wait Times
The sinus surgical wait list in British Columbia continues to grow. The current wait list is beyond what is acceptable by the province's standard; however, this is not likely to improve given the budget constraints of the health…
- Trial name
- NCT02636790
- Testing
- Surgery wait time
- Where
- 2 sites in Canada
- Volunteers
- 20 people
- Sponsor
- University of British Columbia
Postoperative Sore Throat
Efficacy of K-Y Jelly in Prevention of Postoperative Sore Throat After Nasal Surgery
Postoperative sore throat (POST) is a fairly common side effect of general anesthesia which is caused by the mucosal injury and nerve compression associated with tracheal intubation or laryngeal mask airway device insertion.
- Trial name
- NCT05436743
- Testing
- K-Y Jelly, Topical Gel soaked packs, Water soaked packs
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Alaa Gamal
ULTRASOUND-GUIDED PERCUTANEOUS VERSUS TRANS-NASAL PTERYGOPALATINE FOSSA BLOCK IN ENDOSCOPIC TRANS-SPHENOIDAL PITUITARY GLAND SURGERY
Sphenopalatine Ganglion Block in Endoscopic Transphenoidal Pituitary Gland Surgery
The primary aim of this study is to compare the effect of bilateral US guided percutaneous PPFB versus transnasal approach on intraoperative anaesthetic requirements (guided by entropy) in patients undergoing endoscopic…
- Trial name
- NCT06836583
- Testing
- trans-nasal pterygopalatine Fossa block, US-guided infrazygomatic percutaneous pterygopalatine Fossa block
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Donia Hany Saad
Paranasal Sinus Neoplasms
Chemoradiotherapy Followed by Surgery for Advanced Paranasal Sinus Cancer
The purpose of this study is to determine the efficacy of concurrent chemotherapy and radiotherapy pre-operatively in patients with advanced paranasal sinus cancer.
- Trial name
- NCT00347256
- Testing
- cisplatin, targeted radiation therapy, tumor resection
- Volunteers
- 60 people
- Sponsor
- University of Tennessee
Heart Rate, Blood Pressure
Effect of Local Anesthetic on Hemodynamic Measures During Nasal Surgery
1% Lidocaine with 1:100,000 to 1:200,000 of epinephrine is routinely injected into the nasal mucosa during nasal surgery to reduce patient blood loss and improve the surgical field and visibility.
- Conditions
- Heart Rate, Blood Pressure, Blood Loss During Surgery, Surgical Field
- Trial name
- NCT01701960
- Where
- United States
- Sponsor
- Loma Linda University
Esophageal Cancer
The Efficacy of Postoperative Application of HFNC at Acute Phase for Minimally Invasive Esophagectomy Surgery Patients
This is a prospective study that uses the treatment guideline of our chest surgery ICU. Investigators recruited 90 patients who underwent MIE in the National Taiwan University Hospital.
- Trial name
- NCT03816748
- Testing
- High flow nasal cannula, HFNC
- Where
- Taiwan
- Volunteers
- 69 people
- Sponsor
- National Taiwan University Hospital
Nasal Obstruction
Evaluation of the Reliability of AAR as an Independent Tool for Surgical Indication in Nasal Obstruction
Nasal obstruction (NO) affects ~30% of the population and is a very common reason for consultation in otorhinolaryngology (ORL).
- Trial name
- RHINOVE (NCT07379775)
- Testing
- preoperative rhinomanometry
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Deviation Septum Nasal
A Comparison of Esmolol and Remifentanil to Reduce Blood Loss
In this prospective randomized study we aimed to compare the effects of esmolol and remifentanil on intraoperative bleeding surgical field conditions in nasal surgery
- Trial name
- NCT01752959
- Testing
- Remifentanil, Esmolol
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Diskapi Teaching and Research Hospital
Head and Neck Cancer, Pain
Acupuncture or Standard Therapy in Treating Pain and Dysfunction in Patients Who Have Undergone Neck Surgery for Head and Neck Cancer
RATIONALE: Acupuncture may help relieve pain and dysfunction caused by cancer surgery. It is not yet known whether acupuncture is more effective than standard therapy in treating pain and dysfunction in patients who have…
- Trial name
- NCT00090337
- Testing
- acupuncture therapy, standard follow-up care
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Memorial Sloan Kettering Cancer Center