Clinical trials: Nasal Surgery
Stage III Sinonasal Squamous Cell Carcinoma AJCC v6 and v7, Stage IVA Sinonasal Squamous Cell Carcinoma AJCC v7
Chemotherapy Before Surgery and Radiation Therapy or Surgery and Radiation Therapy Alone in Treating Patients With Nasal and Paranasal Sinus Cancer That Can Be Removed by Surgery
This phase II trial studies how well chemotherapy before surgery and radiation therapy works compared to surgery and radiation therapy alone in treating patients with nasal and paranasal sinus cancer that can be removed by…
- Trial name
- NCT03493425
- Testing
- Carboplatin, Cisplatin, Docetaxel
- Where
- 154 sites in United States
- Volunteers
- 82 people
- Sponsor
- ECOG-ACRIN Cancer Research Group
Colonoscopy, Positive-Pressure Respiration
Comparison of High-flow Oxygen With or Without Nasal Positive Airway Pressure (PAP) During Propofol Sedation for Colonoscopy in an Ambulatory Surgical Center
The primary objective of the prospective study is to compare the incidence, duration, and severity of oxygen desaturation in high-risk patients randomized to nasal mask with nasal positive airway pressure (PAP) or standard care…
- Trial name
- NCT05754255
- Testing
- Nasal Cannula, Nasal Positive Airway Pressure System
- Where
- United States
- Sponsor
- Indiana University
Sinusitis
Hot Saline Irrigation Study
Many methods have been used to reduce bleeding during sinus surgery (FESS) in order to allow for the best surgical view and to reduce risk while in surgery.
- Trial name
- HSI (NCT01717274)
- Testing
- Hot saline irrigation
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- St. Paul's Hospital, Canada
Transanal Endoscopic Surgical Procedures, Residual Volume
The Effects of Pharyngeal Packing on the Postoperative Gastric Fluid Volume in Patients Undergoing Functional Endoscopic Nasal Surgery
In this study, the aim is to investigate the effects of Pharyngeal Packing on the perioperative gastric volume in patients undergoing FESS, by ultrasound assessment
- Conditions
- Transanal Endoscopic Surgical Procedures, Residual Volume, Gastric, Ultrasound
- Trial name
- NCT06957275
- Testing
- Nasal packing
- Where
- Egypt
- Volunteers
- 116 people
- Sponsor
- Kasr El Aini Hospital
Minimal Invasive Surgery, Colon Surgery
The Anorectal Function and QoL of Patients Receiving Transrectal NOSE Via Rigid TAMIS Platform in Minimal Invasive Colon Surgery
The primary objective of this study is to prospectively determine and precisely estimate the incidence of Internal Anal Sphincter (IAS) Injury at 12 months following colectomy with Transrectal NOSE.
- Trial name
- NCT07653607
- Testing
- Pre-op and post-op anorectal function and quality of life evaluation
- Volunteers
- 57 people
- Sponsor
- Chang Gung Memorial Hospital
Emergence Agitation, Nasal Surgery
Emergence Agitation
The impact of sugammadex on agitation upon emergence following adult nasal surgeries is an issue which needs to be studied that links anesthetic management with postoperative recovery.
- Trial name
- Sugamadex (NCT07253428)
- Testing
- Neostigmine + Atropine, Sugamadex
- Where
- Saudi Arabia
- Volunteers
- 486 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Sinusitis
Triamcinolone Packing Following Endoscopic Sinus Surgery
Endoscopic sinus surgery (ESS) is a well-established treatment strategy for medically refractory chronic rhinosinusitis. Middle meatus spacers are currently used following ESS to prevent scarring, synechiae formation, and middle…
- Trial name
- NCT04841343
- Testing
- Triamcinolone
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of California, Los Angeles
Pain, Postoperative
Nicotine Administration and Post-operative Opioid Use With Bariatric Surgery
This prospective, randomized, double-blind study will enroll nonsmoking female subjects undergoing laparoscopic bariatric surgery under general anesthesia.
- Trial name
- NCT01194089
- Testing
- Nasal Nicotine Spray, Nasal Normal Saline Spray
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Toby Weingarten
Emergence Agitation
Comparison of Emergence Agitation Between Remimazolam With Flumazenil and Propofol-based Total Intravenous Anesthesia in Patients Undergoing Nasal Surgery
Participants will be randomly assigned to receive general anesthesia with either remimazolaml-based total intravenous anesthesia reversed with flumazenil or propofol-based total intravenous anesthesia.
- Trial name
- NCT07265050
- Testing
- Remimazolam with Flumazenil, Propofol
- Volunteers
- 204 people
- Sponsor
- Seoul National University Hospital
Postoperative Delirium
Dexmedetomidine in Reducing Incidence of Emergence Agitation After Nasal Surgery
Various pharmacological interventions have been attempted previously to prevent postoperative EA with variable results. These include use of opioids, propofol, midazolam, ketamine, magnesium and alpha-2 agonists like clonidine…
- Trial name
- NCT05634148
- Testing
- Dexmedetomidine
- Where
- Saudi Arabia
- Volunteers
- 42 people
- Sponsor
- Security Forces Hospital
Congenital Heart Disease, Oral Aversion
Nasal vs. Oral Intubation for Neonates Requiring Cardiac Surgery
Often, infants struggle to feed orally after surgery for congenital heart disease and may require supplemental feeding interventions at discharge.
- Trial name
- NCT05378685
- Testing
- Endotracheal intubation
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Virginia
Bleeding
Nasal Desmopressin Versus Oral Bisoprolol for Controlling Bleeding During Endoscopic Sinus Surgery
Functional endoscopic sinus surgery (FESS) is well established for treatment of chronic rhinosinusitis and nasal polyps. Masking of the surgical field can lead to severe complication as tissue injury, increase post-operative…
- Trial name
- NCT05430048
- Testing
- nasal Desmopressin
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Zagazig University
Chronic Rhinosinusitis, Rhinosinusitis
Xylitol for Chronic Sinusitis
The purpose of this investigation is to conduct a randomized controlled trial within a subgroup of difficult-to-treat patients with CRS, evaluating the use of topical xylitol treatment concurrently with topical…
- Conditions
- Chronic Rhinosinusitis, Rhinosinusitis, Sinusitis, Drain Sinus
- Trial name
- NCT03229551
- Testing
- Xylitol, Saline
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Ochsner Health System
Head and Neck Cancer, Pain
Acupuncture or Standard Therapy in Treating Pain and Dysfunction in Patients Who Have Undergone Neck Surgery for Head and Neck Cancer
RATIONALE: Acupuncture may help relieve pain and dysfunction caused by cancer surgery. It is not yet known whether acupuncture is more effective than standard therapy in treating pain and dysfunction in patients who have…
- Trial name
- NCT00090337
- Testing
- acupuncture therapy, standard follow-up care
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Chronic Rhinosinusitis
Povidone-Iodine Nasal Irrigation After Surgery for Chronic Rhinosinusitis
This prospective randomized controlled trial evaluates the effectiveness and safety of different nasal irrigation solutions for postoperative care after endoscopic sinus surgery in patients with chronic rhinosinusitis.
- Trial name
- NCT07470242
- Testing
- Normal Saline Nasal Irrigation, Acetylcysteine (Mucomyst) Nasal Irrigation, Povidone-Iodine Nasal Irrigation
- Where
- South Korea
- Volunteers
- 48 people
- Sponsor
- Pusan National University Hospital
Deviation Septum Nasal
A Comparison of Esmolol and Remifentanil to Reduce Blood Loss
In this prospective randomized study we aimed to compare the effects of esmolol and remifentanil on intraoperative bleeding surgical field conditions in nasal surgery
- Trial name
- NCT01752959
- Testing
- Remifentanil, Esmolol
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Diskapi Teaching and Research Hospital
Nasal Surgery, Snoring
Nasal Surgery in Snoring and Obstructive Sleep Apnea
This study aimed to evaluate the effect of isolated nasal surgery on sleep-disordered breathing, particularly apnea-hypopnea index (AHI) and snoring index (SI), Apnea index (AI) and minimal arterial oxygen saturation (MAO2) in…
- Conditions
- Nasal Surgery, Snoring, Obstructive Sleep Apnea
- Trial name
- NCT07622745
- Testing
- Septoplasty with partial inferior turbinectomy, Nasal polypectomy, Partial inferior turbinectomy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Al-Azhar University
PONV
Risk Factors for Postoperative Nausea and Vomiting After Nasal Surgery Under General Anesthesia
The goal of this observational study is to learn how often postoperative nausea and vomiting occur in adults undergoing nasal surgery under general anesthesia and to identify factors associated with these events.
- Trial name
- N-PONV (NCT07749079)
- Volunteers
- 1,000 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Allergic Asthma, Allergic Rhinitis
Efficacy of Face Mask in Reducing Respiratory Allergic Symptoms in Birch-allergic Subjects in ALYATEC Exposure Chamber
There is no clinical evidence that face masks are efficient in birch pollen-induced asthma. As the use of face masks has become widespread worldwide to limit the spread of SARS-CoV-2, this study aims to demonstrate the clinical…
- Trial name
- NCT06267261
- Testing
- KOLMI® surgical face mask (OP-Air)
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Alyatec
Laryngologic Surgical Procedures
Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) and Short Laryngologic Surgery
The purpose of this study is to investigate whether selected, short laryngologic surgical procedures can be safely and potentially more effectively performed without the use of endotracheal tube or jet ventilation, under…
- Trial name
- NCT03091179
- Testing
- THRIVE, Endotracheal tube
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Stanford University