Clinical trials: Natural Orifice Transluminal Endoscopic Surgery
Uterine Diseases
Hysterectomy by Transabdominal Laparoscopy or NOTES
Objective: To randomly compare hysterectomy by vaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) versus laparoscopy uterus in women with benign gynecological pathology.
- Trial name
- HALON (NCT02631837)
- Testing
- vNOTES hysterectomy, LSC hysterectomy
- Where
- Belgium
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Imelda Hospital, Bonheiden
Vaginal Prolapse
0050-19-RMB CTIL - VNOTES Compared to VH for Vaginal Apex Prolapse
VNOTES (Transvaginal natural orifice transluminal endoscopic surgery) is a relatively new surgery for Hysterectomy and Uterosacral ligament suspension to treat Vaginal prolapse.
- Trial name
- NCT04078802
- Testing
- VNOTES/VH
- Volunteers
- 60 people
- Sponsor
- Rambam Health Care Campus
Abnormal Uterine Bleeding, Unspecified, Benign Gynecological Disease
The Learning Curve of a Gynecology and Obstetrics Resident Performing Vaginal Natural Orifice Transluminal Endoscopic Surgery (V-NOTES) Hysterectomy in a University Hospital
This prospective observational study aims to evaluate the learning curve of obstetrics and gynecology residents performing Vaginal Natural Orifice Transluminal Endoscopic Surgery (V-NOTES) hysterectomy in a university hospital…
- Conditions
- Abnormal Uterine Bleeding, Unspecified, Benign Gynecological Disease, Adenomyosis of Uterus, Uterine Leiomyomas
- Trial name
- LC of V-NOTES (NCT07465822)
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people
- Sponsor
- Cukurova University
Endometrial Adenocarcinoma, Endometrial Cancer
Comparison of Sentinel Lymph Node Applications in Endometrial Cancer Cases Performed With Vaginal Natural Orifice Transluminal Endoscopic Surgery (V-NOTES) and Conventional Laparoscopy
Endometrial cancer is a common cancer in women, and surgery is usually the first step in treatment. During surgery, doctors often check nearby lymph nodes to see if the cancer has spread.
- Trial name
- V-COSMOS (NCT07583329)
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Cukurova University
Pelvic Organ Prolapse
Laparoscopic Sacropexy and Vaginal Natural Orifice Transluminal Endoscopic Surgery Shull Suspension Comparison Trial
This is a prospective, randomized multicenter study whose objective is to compare two surgical techniques routinely used at our center for the correction of pelvic organ prolapse (laparoscopic cervicosacropexis versus…
- Trial name
- V-PULSE (NCT05856201)
- Testing
- Laparoscopic cervicosacropexy, Shull technique via V-NOTES
- Volunteers
- 90 people
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana
Salpingectomy
vNOTES Salpingo-oophorectomy or Bilateral Salpingectomy Compared With Laparoscopic.
Objective: To compare the vNOTES approach versus conventional laparoscopic approach used in elective Salpingo-oophorectomy surgery for benign disease or bilateral salpingectomy for sterilization.
- Trial name
- NCT05228938
- Testing
- VNOTES, laparoscopic
- Where
- Israel
- Volunteers
- 1 people
- Sponsor
- HaEmek Medical Center, Israel
Natural Orifice Endoscopic Surgery, Disease, Adnexal
Notes Adnexectomy for Benign Pathology Compared to Laparoscopic Excision
Objective: To compare vNOTES (vaginal Natural Orifice Transluminal Endoscopic Surgery) and established laparoscopic removal of benign adnexal masses Study design: Randomized controlled/single…
- Conditions
- Natural Orifice Endoscopic Surgery, Disease, Adnexal, Laparoscopic Surgery
- Trial name
- NOTABLE (NCT02630329)
- Testing
- vNOTES adnexectomy, Laparoscopic adnexectomy
- Where
- Belgium
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Imelda Hospital, Bonheiden
Rectal Neoplasms, Rectal Cancer Patients
Optimization and Standardization of Single-Port Robotic Transanal Minimally Invasive Surgery for Rectal Tumor Excision
Title Case Summary: "This study evaluates the safety, feasibility, and short-term clinical outcomes of a new surgical approach called Single-Port (SP) Robotic Transanal Minimally Invasive Surgery (SPR TAMIS) for treating rectal…
- Conditions
- Rectal Neoplasms, Rectal Cancer Patients, Rectal Benign Lesions
- Trial name
- NCT07522294
- Testing
- da Vinci SP Surgical System
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- Jeng-Fu You
Cervical Cancer, Endometrial Cancer，Endometrial Lesion & Adnexal Lesion，Ectopic Pregnancy & Infertility，Pelvic Obstructive Disorder & Genital Tract Deformity
Clinical Application of Laparo-endoscopic Single-site Surgery and Natural Orifice Transluminal Endoscopic in Gynecology
The GLESS registry is a prospective multi-center observational registry. Data from the time of patient admission, operation, discharge, and follow-up will be collected for this registry.
- Trial name
- GLESS (NCT04096872)
- Where
- China
- Volunteers
- 9,000 people
- Sponsor
- Peking Union Medical College Hospital
Abdominal Adhesions
Natural Orifice Transgastric Endoscopic (NOTES) Transgastric Diagnostic Peritoneoscopy With Laparoscopic Assistance
The study will document being able to successfully perform transgastric diagnostic peritoneoscopy (laparoscopic visualization) using a small collection of study surgical tools.
- Trial name
- NOTES (NCT00962650)
- Testing
- Transgastric diagnostic peritoneoscopy with laparoscopic assistance
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Ethicon Endo-Surgery
Obese, Surgery
Does BMI Influence Pain Follow vNOTE Surgery
Overweight and obesity are increasing dramatically worldwide and contribute substantially to the burden of morbidity and mortality.
- Conditions
- Obese, Surgery, Pain, Postoperative
- Trial name
- BMIVNOTES (NCT05230407)
- Testing
- Visual analog scale (VAS) assesment of pain
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Ectopic Pregnancy
Comparison of vNOTES and Laparoscopic Salpingectomy in the Surgical Treatment of Ectopic Pregnancy
This study compares vNOTES salpingectomy and laparoscopic salpingectomy in the treatment of ectopic pregnancy, focusing on outcomes such as operative time, postoperative pain, and recovery.
- Trial name
- vNOTES (NCT07057115)
- Testing
- vNOTES Salpingectomy Group., Laparoscopic Salpingectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Leiomyoma, Uterine, Benign Gynecological Disease
Deep Neuromuscular Blockade and a Low-Residue Diet for the Surgical Field in vNOTES Hysterectomy
vNOTES (vaginal natural orifice transluminal endoscopic surgery) hysterectomy is performed entirely through the vagina, with no abdominal incision.
- Conditions
- Leiomyoma, Uterine, Benign Gynecological Disease, Abnormal Uterine Bleeding (AUB), Uterine Prolapse
- Trial name
- vNOTES_NMBDIET (NCT07730970)
- Testing
- Deep Neuromuscular Blockade (NMB), Standard (moderate) neuromuscular blockade, Preoperative low-residue diet
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Surgery, Gynecologic Disease
Study Evaluating the Success Rate of Outpatient Management of the Total Benign Hysterectomy by Transvaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) Compared to Each of the Two Laparoscopic Routes (Conventional and Robot-assisted).
Benign total hysterectomy is one of the most commonly performed gynecological surgery. Conventionally performed by a classical surgical approach, it is now provided routinely and for several years by laparoscopy and more recently…
- Trial name
- HYSTERAMBU (NCT06471049)
- Testing
- Benign Hysterectomy
- Where
- France
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Elsan
Calculus of Gallbladder With or Without Cholecystitis, Laparoscopic Cholecystectomy
Needlescopic Versus Transvaginal/Transumbilical Cholecystectomy
Laparoscopic surgery has become the golden standard for the removal of the gallbladder. Recently, developments have been made so that operations can be performed through a natural orifice instead of the abdominal wall, thus…
- Trial name
- NATCH (NCT01685775)
- Testing
- Transvaginal/transumbilical, Needlescopic with 3 trocars
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University of Witten/Herdecke
Enlarged Uterus, Adenomyosis
Comparing the Efficacy of TU-LESS and vNOTES for Hysterectomy of Enlarged Uterus
Enlarged uterus is frequently encountered in clinical practice, and its incidence due to conditions such as adenomyosis, uterine fibroids, and other gynecological disorders has steadily increased over the years statistically.
- Conditions
- Enlarged Uterus, Adenomyosis, Uterine Fibroids (UF)
- Trial name
- NCT06663553
- Testing
- TU-LESS, vNOTES
- Where
- China
- Volunteers
- 210 people
- Sponsor
- West China Second University Hospital
Sterility, Female
Patient-centered Outcomes After Permanent Female Sterilization Procedure(POPS Trial)
The purpose of this study is to compare and capture key elements of the patient experience, quality of recovery, preferences and satisfaction after laparoscopic salpingectomy done via 3 different routes.
- Trial name
- POPS (NCT05518175)
- Testing
- Traditional laparoscopy, Single site laparoscopy, V-Notes surgery
- Where
- United States
- Volunteers
- 255 people
- Sponsor
- The University of Texas Health Science Center, Houston
Achalasia, Dysphagia
Efficacy & Safety of Submucosal Endoscopic Myotomy With Mucosal Flap (SEMF) in the Treatment of Patients With Achalasia
The purpose of this study is to learn about the safety and usefulness of a procedure called endoscopic submucosal myotomy, which is a new technique in the treatment of achalasia.
- Trial name
- NCT01438398
- Testing
- Submucosal endoscopic myotomy with mucosal flap technique, Submucosal Endoscopic Mucosal Flap (SEMF) technique
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Winthrop University Hospital
Colorectal Cancer
Natural Orifice Transluminal Endoscopic Surgery for Colorectal Cancer
The purpose of this study is to assess different hybrid natural orifice transluminal endoscopic surgery techniques in management of colorectal cancer as regard: feasibility of the technique, short term oncologic outcome and…
- Trial name
- NOTES (NCT02549456)
- Testing
- natural orifice specimen extraction, Laparoendoscopic resection
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Laparoscopy-assisted Surgery, Total Laparoscopic Surgery With no Incision (Natural Orifice Transluminal Endoscopic Surgery, NOSES)
The Comparison Between Traditional Laparoscopy-assisted Surgery and NOSES in Radical Resection of Colorectal Cancer
This study is to compare the short-term and long-term outcomes of traditional laparoscopy-assisted surgery and total laparoscopic surgery with no incision (natural orifice transluminal endoscopic surgery, NOSES) for colorectal…
- Trial name
- NCT03470142
- Testing
- traditional laparoscopy-assisted surgery, total laparoscopic surgery with no incision (natural orifice transluminal endoscopic surgery, NOSES)
- Where
- China
- Volunteers
- 158 people
- Sponsor
- Dong Yang